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Results: 1-23 |
Results: 23
A RAPID IN-VITRO ASSAY FOR EVALUATION OF METABOLISM-DEPENDENT CYTOTOXICITY OF ANTIEPILEPTIC DRUGS ON ISOLATED HUMAN-LYMPHOCYTES
Authors: TABATABAEI AR THIES RL FARRELL K ABBOTT FS
Citation: Ar. Tabatabaei et al., A RAPID IN-VITRO ASSAY FOR EVALUATION OF METABOLISM-DEPENDENT CYTOTOXICITY OF ANTIEPILEPTIC DRUGS ON ISOLATED HUMAN-LYMPHOCYTES, Fundamental and applied toxicology, 37(2), 1997, pp. 181-189
A COMPARATIVE INVESTIGATION OF 2-PROPYL-4-PENTENOIC ACID (4-ENE VPA) AND ITS ALPHA-FLUORINATED ANALOG - PHASE-II METABOLISM AND PHARMACOKINETICS
Authors: TANG W ABBOTT FS
Citation: W. Tang et Fs. Abbott, A COMPARATIVE INVESTIGATION OF 2-PROPYL-4-PENTENOIC ACID (4-ENE VPA) AND ITS ALPHA-FLUORINATED ANALOG - PHASE-II METABOLISM AND PHARMACOKINETICS, Drug metabolism and disposition, 25(2), 1997, pp. 219-227
TIME-COURSE OF ALPHA-FLUORINATED VALPROIC ACID IN MOUSE-BRAIN AND SERUM AND ITS EFFECT ON SYNAPTOSOMAL GAMMA-AMINOBUTYRIC-ACID LEVELS IN COMPARISON TO VALPROIC ACID
Authors: TANG W PALATY J ABBOTT FS
Citation: W. Tang et al., TIME-COURSE OF ALPHA-FLUORINATED VALPROIC ACID IN MOUSE-BRAIN AND SERUM AND ITS EFFECT ON SYNAPTOSOMAL GAMMA-AMINOBUTYRIC-ACID LEVELS IN COMPARISON TO VALPROIC ACID, The Journal of pharmacology and experimental therapeutics, 282(3), 1997, pp. 1163-1172
CHARACTERIZATION OF THIOL-CONJUGATED METABOLITES OF 2-PROPYLPENT-4-ENOIC ACID (4-ENE VPA), A TOXIC METABOLITE OF VALPROIC ACID, BY ELECTROSPRAY TANDEM MASS-SPECTROMETRY
Authors: TANG W ABBOTT FS
Citation: W. Tang et Fs. Abbott, CHARACTERIZATION OF THIOL-CONJUGATED METABOLITES OF 2-PROPYLPENT-4-ENOIC ACID (4-ENE VPA), A TOXIC METABOLITE OF VALPROIC ACID, BY ELECTROSPRAY TANDEM MASS-SPECTROMETRY, Journal of mass spectrometry., 31(8), 1996, pp. 926-936
BIOACTIVATION OF A TOXIC METABOLITE OF VALPROIC ACID, (E)-2-PROPYL-2,4-PENTADIENOIC ACID, VIA GLUCURONIDATION - LC MS/MS CHARACTERIZATION OF THE GSH-GLUCURONIDE DICONJUGATES/
Authors: TANG W ABBOTT FS
Citation: W. Tang et Fs. Abbott, BIOACTIVATION OF A TOXIC METABOLITE OF VALPROIC ACID, (E)-2-PROPYL-2,4-PENTADIENOIC ACID, VIA GLUCURONIDATION - LC MS/MS CHARACTERIZATION OF THE GSH-GLUCURONIDE DICONJUGATES/, Chemical research in toxicology, 9(2), 1996, pp. 517-526
CYTOTOXICITY OF UNSATURATED METABOLITES OF VALPROIC ACID AND PROTECTION BY VITAMIN-C AND VITAMIN-E IN GLUTATHIONE-DEPLETED RAT HEPATOCYTES
Authors: JURIMAROMET M ABBOTT FS TANG W HUANG HS WHITEHOUSE LW
Citation: M. Jurimaromet et al., CYTOTOXICITY OF UNSATURATED METABOLITES OF VALPROIC ACID AND PROTECTION BY VITAMIN-C AND VITAMIN-E IN GLUTATHIONE-DEPLETED RAT HEPATOCYTES, Toxicology, 112(1), 1996, pp. 69-85
COMPARATIVE EFFECTS OF CARBAMAZEPINE AND CARBAMAZEPINE-10,11-EPOXIDE ON HEPATIC CYTOCHROMES-P450 IN THE RAT
Authors: PANESAR SK BANDIERA SM ABBOTT FS
Citation: Sk. Panesar et al., COMPARATIVE EFFECTS OF CARBAMAZEPINE AND CARBAMAZEPINE-10,11-EPOXIDE ON HEPATIC CYTOCHROMES-P450 IN THE RAT, Drug metabolism and disposition, 24(6), 1996, pp. 619-627
CONJUGATION OF GLUTATHIONE WITH A TOXIC METABOLITE OF VALPROIC ACID, (E)-2-PROPYL-2,4-PENTADIENOIC ACID, CATALYZED BY RAT HEPATIC GLUTATHIONE-S-TRANSFERASES
Authors: TANG W BOREL AG ABBOTT FS
Citation: W. Tang et al., CONJUGATION OF GLUTATHIONE WITH A TOXIC METABOLITE OF VALPROIC ACID, (E)-2-PROPYL-2,4-PENTADIENOIC ACID, CATALYZED BY RAT HEPATIC GLUTATHIONE-S-TRANSFERASES, Drug metabolism and disposition, 24(4), 1996, pp. 436-446
BINDING OF A VALPROATE METABOLITE TO THE TRIFUNCTIONAL PROTEIN OF FATTY-ACID OXIDATION
Authors: BALDWIN GS ABBOTT FS NAU H
Citation: Gs. Baldwin et al., BINDING OF A VALPROATE METABOLITE TO THE TRIFUNCTIONAL PROTEIN OF FATTY-ACID OXIDATION, FEBS letters, 384(1), 1996, pp. 58-60
DETERMINATION OF VALPROIC ACID AND ITS METABOLITES USING GAS-CHROMATOGRAPHY WITH MASS-SELECTIVE DETECTION - APPLICATION TO SERUM AND URINE SAMPLES FROM SHEEP
Authors: YU DC GORDON JD ZHENG JJ PANESAR SK RIGGS KW RURAK DW ABBOTT FS
Citation: Dc. Yu et al., DETERMINATION OF VALPROIC ACID AND ITS METABOLITES USING GAS-CHROMATOGRAPHY WITH MASS-SELECTIVE DETECTION - APPLICATION TO SERUM AND URINE SAMPLES FROM SHEEP, Journal of chromatography B. Biomedical applications, 666(2), 1995, pp. 269-281
SIMULTANEOUS ANALYSIS OF DIPHENYLMETHOXYACETIC ACID, A METABOLITE OF DIPHENHYDRAMINE, AND ITS DEUTERIUM-LABELED STABLE-ISOTOPE ANALOG IN OVINE PLASMA AND URINE
Authors: TONN GR ABBOTT FS RURAK DW AXELSON JE
Citation: Gr. Tonn et al., SIMULTANEOUS ANALYSIS OF DIPHENYLMETHOXYACETIC ACID, A METABOLITE OF DIPHENHYDRAMINE, AND ITS DEUTERIUM-LABELED STABLE-ISOTOPE ANALOG IN OVINE PLASMA AND URINE, Journal of chromatography B. Biomedical applications, 663(1), 1995, pp. 67-81
CHARACTERIZATION OF NOVEL ISOCYANATE-DERIVED METABOLITES OF THE FORMAMIDE N-FORMYLAMPHETAMINE WITH THE COMBINED USE OF ELECTROSPRAY MASS-SPECTROMETRY AND STABLE-ISOTOPE METHODOLOGY
Authors: BOREL AG ABBOTT FS
Citation: Ag. Borel et Fs. Abbott, CHARACTERIZATION OF NOVEL ISOCYANATE-DERIVED METABOLITES OF THE FORMAMIDE N-FORMYLAMPHETAMINE WITH THE COMBINED USE OF ELECTROSPRAY MASS-SPECTROMETRY AND STABLE-ISOTOPE METHODOLOGY, Chemical research in toxicology, 8(6), 1995, pp. 891-899
FLUORINATED ANALOGS AS MECHANISTIC PROBES IN VALPROIC ACID HEPATOTOXICITY - HEPATIC MICROVESICULAR STEATOSIS AND GLUTATHIONE STATUS
Authors: TANG W BOREL AG FUJIMIYA T ABBOTT FS
Citation: W. Tang et al., FLUORINATED ANALOGS AS MECHANISTIC PROBES IN VALPROIC ACID HEPATOTOXICITY - HEPATIC MICROVESICULAR STEATOSIS AND GLUTATHIONE STATUS, Chemical research in toxicology, 8(5), 1995, pp. 671-682
THE PHARMACOKINETICS OF VALPROIC ACID IN PREGNANT SHEEP AFTER MATERNAL AND FETAL INTRAVENOUS BOLUS ADMINISTRATION
Authors: GORDON JD RIGGS KW RURAK DW KWAN E HALL C ABBOTT FS
Citation: Jd. Gordon et al., THE PHARMACOKINETICS OF VALPROIC ACID IN PREGNANT SHEEP AFTER MATERNAL AND FETAL INTRAVENOUS BOLUS ADMINISTRATION, Drug metabolism and disposition, 23(12), 1995, pp. 1383-1389
STRUCTURE-ACTIVITY-RELATIONSHIPS OF UNSATURATED ANALOGS OF VALPROIC ACID
Authors: PALATY J ABBOTT FS
Citation: J. Palaty et Fs. Abbott, STRUCTURE-ACTIVITY-RELATIONSHIPS OF UNSATURATED ANALOGS OF VALPROIC ACID, Journal of medicinal chemistry, 38(17), 1995, pp. 3398-3406
RAPID ASSAY FOR GAMMA-AMINOBUTYRIC-ACID IN MOUSE-BRAIN SYNAPTOSOMES USING GAS-CHROMATOGRAPHY MASS-SPECTROMETRY
Authors: PALATY J BURTON R ABBOTT FS
Citation: J. Palaty et al., RAPID ASSAY FOR GAMMA-AMINOBUTYRIC-ACID IN MOUSE-BRAIN SYNAPTOSOMES USING GAS-CHROMATOGRAPHY MASS-SPECTROMETRY, Journal of chromatography B. Biomedical applications, 662(1), 1994, pp. 85-90
DETERMINATION OF METOCLOPRAMIDE AND 2 OF ITS METABOLITES USING A SENSITIVE AND SELECTIVE GAS-CHROMATOGRAPHIC MASS-SPECTROMETRIC ASSAY
Authors: RIGGS KW SZEITZ A RURAK DW MUTLIB AE ABBOTT FS AXELSON JE
Citation: Kw. Riggs et al., DETERMINATION OF METOCLOPRAMIDE AND 2 OF ITS METABOLITES USING A SENSITIVE AND SELECTIVE GAS-CHROMATOGRAPHIC MASS-SPECTROMETRIC ASSAY, Journal of chromatography B. Biomedical applications, 660(2), 1994, pp. 315-325
DETERMINATION OF METOCLOPRAMIDE AND 2 OF ITS METABOLITES USING A SENSITIVE AND SELECTIVE GAS-CHROMATOGRAPHIC MASS-SPECTROMETRIC ASSAY
Authors: RIGGS KW SZEITZ A RURAK DW MUTLIB AE ABBOTT FS AXELSON JE
Citation: Kw. Riggs et al., DETERMINATION OF METOCLOPRAMIDE AND 2 OF ITS METABOLITES USING A SENSITIVE AND SELECTIVE GAS-CHROMATOGRAPHIC MASS-SPECTROMETRIC ASSAY, Journal of chromatography B. Biomedical applications, 660(2), 1994, pp. 315-325
SIMULTANEOUS ANALYSIS OF DIPHENHYDRAMINE AND A STABLE-ISOTOPE ANALOG (H-2(10) DIPHENHYDRAMINE USING CAPILLARY GAS-CHROMATOGRAPHY WITH MASS-SELECTIVE DETECTION IN BIOLOGICAL-FLUIDS FROM CHRONICALLY INSTRUMENTEDPREGNANT EWES
Authors: TONN GR MUTLIB A ABBOTT FS RURAK DW AXELSON JE
Citation: Gr. Tonn et al., SIMULTANEOUS ANALYSIS OF DIPHENHYDRAMINE AND A STABLE-ISOTOPE ANALOG (H-2(10) DIPHENHYDRAMINE USING CAPILLARY GAS-CHROMATOGRAPHY WITH MASS-SELECTIVE DETECTION IN BIOLOGICAL-FLUIDS FROM CHRONICALLY INSTRUMENTEDPREGNANT EWES, Biological mass spectrometry, 22(11), 1993, pp. 633-642
SENSITIVE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC METHOD FOR DIRECT SEPARATION OF LABETALOL STEREOISOMERS IN BIOLOGICAL-FLUIDS USING AN ALPHA-1-ACID GLYCOPROTEIN STATIONARY-PHASE
Authors: DOROUDIAN A YELESWARAM K RURAK DW ABBOTT FS AXELSON JE
Citation: A. Doroudian et al., SENSITIVE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC METHOD FOR DIRECT SEPARATION OF LABETALOL STEREOISOMERS IN BIOLOGICAL-FLUIDS USING AN ALPHA-1-ACID GLYCOPROTEIN STATIONARY-PHASE, Journal of chromatography. Biomedical applications, 619(1), 1993, pp. 79-86
IDENTIFICATION OF CARBAMOYLATED THIOL CONJUGATES AS METABOLITES OF THE ANTINEOPLASTIC 1-(2-CHLOROETHYL)-3-CYCLOHEXYL-1-NITROSOUREA, IN RATSAND HUMANS
Authors: BOREL AG ABBOTT FS
Citation: Ag. Borel et Fs. Abbott, IDENTIFICATION OF CARBAMOYLATED THIOL CONJUGATES AS METABOLITES OF THE ANTINEOPLASTIC 1-(2-CHLOROETHYL)-3-CYCLOHEXYL-1-NITROSOUREA, IN RATSAND HUMANS, Drug metabolism and disposition, 21(5), 1993, pp. 889-901
METABOLIC PROFILING OF CLOBAZAM, A 1,5-BENZODIAZEPINE, IN RATS
Authors: BOREL AG ABBOTT FS
Citation: Ag. Borel et Fs. Abbott, METABOLIC PROFILING OF CLOBAZAM, A 1,5-BENZODIAZEPINE, IN RATS, Drug metabolism and disposition, 21(3), 1993, pp. 415-427
TRANSPLACENTAL AND NONPLACENTAL CLEARANCES, METABOLISM AND PHARMACODYNAMICS OF LABETALOL IN THE FETAL LAMB AFTER DIRECT INTRAVENOUS ADMINISTRATION
Authors: YELESWARAM K RURAK DW KWAN E HALL C DOROUDIAN A WRIGHT MR ABBOTT FS AXELSON JE
Citation: K. Yeleswaram et al., TRANSPLACENTAL AND NONPLACENTAL CLEARANCES, METABOLISM AND PHARMACODYNAMICS OF LABETALOL IN THE FETAL LAMB AFTER DIRECT INTRAVENOUS ADMINISTRATION, The Journal of pharmacology and experimental therapeutics, 267(1), 1993, pp. 425-431
Risultati: 1-23 |