Authors:
TURNER SR
STROHBACH JW
TOMMASI RA
ARISTOFF PA
JOHNSON PD
SKULNICK HI
DOLAK LA
SEEST EP
TOMICH PK
BOHANAN MJ
HORNG MM
LYNN JC
CHONG KT
HINSHAW RR
WATENPAUGH KD
JANAKIRAMAN MN
THAISRIVONGS S
Citation: Sr. Turner et al., TIPRANAVIR (PNU-140690) - A POTENT, ORALLY BIOAVAILABLE NONPEPTIDIC HIV PROTEASE INHIBITOR OF THE 5,6-DIHYDRO-4-HYDROXY-2-PYRONE SULFONAMIDE CLASS, Journal of medicinal chemistry, 41(18), 1998, pp. 3467-3476
Authors:
SKULNICK HI
JOHNSON PD
ARISTOFF PA
MORRIS JK
LOVASZ KD
HOWE WJ
WATENPAUGH KD
JANAKIRAMAN MN
ANDERSON DJ
REISCHER RJ
SCHWARTZ TM
BANITT LS
TOMICH PK
LYNN JC
HORNG MM
CHONG KT
HINSHAW RR
DOLAK LA
SEEST EP
SCHWENDE FJ
RUSH BD
HOWARD GM
TOTH LN
WILKINSON KR
KAKUK TJ
JOHNSON CW
COLE SL
ZAYA RM
ZIPP GL
POSSERT PL
DALGA RJ
ZHONG WZ
WILLIAMS MG
ROMINES KR
Citation: Hi. Skulnick et al., STRUCTURE-BASED DESIGN OF NONPEPTIDIC HIV PROTEASE INHIBITORS - THE SULFONAMIDE-SUBSTITUTED CYCLOOCTYLPYRANONES, Journal of medicinal chemistry, 40(7), 1997, pp. 1149-1164
Authors:
THAISRIVONGS S
ROMERO DL
TOMMASI RA
JANAKIRAMAN MN
STROHBACH JW
TURNER SR
BILES C
MORGE RR
JOHNSON PD
ARISTOFF PA
TOMICH PK
LYNN JC
HORNG MM
CHONG KT
HINSHAW RR
HOWE WJ
FINZEL BC
WATENPAUGH KD
Citation: S. Thaisrivongs et al., STRUCTURE-BASED DESIGN OF HIV PROTEASE INHIBITORS - 5,6-DIHYDRO-4-HYDROXY-2-PYRONES AS EFFECTIVE, NONPEPTIDIC INHIBITORS, Journal of medicinal chemistry, 39(23), 1996, pp. 4630-4642
Authors:
THAISRIVONGS S
SKULNICK HI
TURNER SR
STROHBACH JW
TOMMASI RA
JOHNSON PD
ARISTOFF PA
JUDGE TM
GAMMILL RB
MORRIS JK
ROMINES KR
CHRUSCIEL RA
HINSHAW RR
CHONG KT
TARPLEY WG
POPPE SM
SLADE DE
LYNN JC
HORNG MM
TOMICH PK
SEEST EP
DOLAK LA
HOWE WJ
HOWARD GM
SCHWENDE FJ
TOTH LN
PADBURY GE
WILSON GJ
SHIOU LH
ZIPP GL
WILKINSON KF
RUSH BD
RUWART MJ
KOEPLINGER KA
ZHAO ZY
COLE S
ZAYA RM
KAKUK TJ
JANAKIRAMAN MN
WATENPAUGH KD
Citation: S. Thaisrivongs et al., STRUCTURE-BASED DESIGN OF HIV PROTEASE INHIBITORS - SULFONAMIDE-CONTAINING 5,6-DIHYDRO-4-HYDROXY-2-PYRONES AS NONPEPTIDIC INHIBITORS, Journal of medicinal chemistry, 39(22), 1996, pp. 4349-4353
Authors:
ALTHAUS IW
CHOU KC
LEMAY RJ
FRANKS KM
DEIBEL MR
KEZDY FJ
RESNICK L
BUSSO ME
SO AG
DOWNEY KM
ROMERO DL
THOMAS RC
ARISTOFF PA
TARPLEY WG
REUSSER F
Citation: Iw. Althaus et al., THE BENZYLTHIO-PYRIMIDINE U-31,355, A POTENT INHIBITOR OF HIV-1 REVERSE-TRANSCRIPTASE, Biochemical pharmacology, 51(6), 1996, pp. 743-750
Authors:
SKULNICK HI
JOHNSON PD
HOWE WJ
TOMICH PK
CHONG KT
WATENPAUGH KD
JANAKIRAMAN MN
DOLAK LA
MCGRATH JP
LYNN JC
HORNG MM
HINSHAW RR
ZIPP GL
RUWART MJ
SCHWENDE FJ
ZHONG WZ
PADBURY GE
DALGA RJ
SHIOU LH
POSSERT PL
RUSH BD
WILKINSON KF
HOWARD GM
TOTH LN
WILLIAMS MG
KAKUK TJ
COLE SL
ZAYA RM
LOVASZ KD
MORRIS JK
ROMINES KR
THAISRIVONGS S
ARISTOFF PA
Citation: Hi. Skulnick et al., STRUCTURE-BASED DESIGN OF SULFONAMIDE-SUBSTITUTED NONPEPTIDIC HIV PROTEASE INHIBITORS, Journal of medicinal chemistry, 38(26), 1995, pp. 4968-4971
Authors:
ROMERO DL
MORGE RA
BILES C
BERRIOSPENA TN
MAY PD
PALMER JR
JOHNSON PD
SMITH HW
BUSSO M
TAN CK
VOORMAN RL
REUSSER F
ALTHAUS IW
DOWNEY KM
SO AG
RESNICK L
TARPLEY WG
ARISTOFF PA
Citation: Dl. Romero et al., DISCOVERY, SYNTHESIS, AND BIOACTIVITY OF BIS(HETEROARYL)PIPERAZINES .1. A NOVEL CLASS OF NONNUCLEOSIDE HIV-1 REVERSE-TRANSCRIPTASE INHIBITORS, Journal of medicinal chemistry, 37(7), 1994, pp. 999-1014
Authors:
ALTHAUS IW
CHOU JJ
GONZALES AJ
LEMAY RJ
DEIBEL MR
CHOU KC
KEZDY FJ
ROMERO DL
THOMAS RC
ARISTOFF PA
TARPLEY WG
REUSSER F
Citation: Iw. Althaus et al., STEADY-STATE KINETIC-STUDIES WITH THE POLYSULFONATE U-9843, AN HIV REVERSE-TRANSCRIPTASE INHIBITOR, Experientia, 50(1), 1994, pp. 23-28
Authors:
ABRAHAM I
WOLF CL
SAMPSON KE
LABORDE AL
SHELLY JA
ARISTOFF PA
SKULNICK HI
Citation: I. Abraham et al., K252A, KT5720, KT5926, AND U98017 SUPPORT PACLITAXEL (TAXOL)-DEPENDENT CELLS AND SYNERGIZE WITH PACLITAXEL, Cancer research, 54(22), 1994, pp. 5889-5894
Authors:
ALTHAUS IW
CHOU JJ
GONZALES AJ
DEIBEL MR
CHOU KC
KEZDY FJ
ROMERO DL
THOMAS RC
ARISTOFF PA
TARPLEY WG
REUSSER F
Citation: Iw. Althaus et al., KINETIC-STUDIES WITH THE NONNUCLEOSIDE HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE INHIBITOR U-90152E, Biochemical pharmacology, 47(11), 1994, pp. 2017-2028
Authors:
DUEWEKE TJ
POPPE SM
ROMERO DL
SWANEY SM
SO AG
DOWNEY KM
ALTHAUS IW
REUSSER F
BUSSO M
RESNICK L
MAYERS DI
LANE J
ARISTOFF PA
THOMAS RC
TARPLEY WG
Citation: Tj. Dueweke et al., U-90152, A POTENT INHIBITOR OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REPLICATION, Antimicrobial agents and chemotherapy, 37(5), 1993, pp. 1127-1131
Citation: Pa. Aristoff et al., SYNTHESIS AND BIOCHEMICAL EVALUATION OF THE CBI-PDE-I-DIMER, A BENZANNELATED ANALOG OF (-CC-106K THAT ALSO PRODUCES DELAYED TOXICITY IN MICE()), Journal of medicinal chemistry, 36(14), 1993, pp. 1956-1963
Authors:
ALTHAUS IW
GONZALES AJ
CHOU JJ
ROMERO DL
DEIBEL MR
CHOU KC
KEZDY FJ
RESNICK L
BUSSO ME
SO AG
DOWNEY KM
THOMAS RC
ARISTOFF PA
TARPLEY WG
REUSSER F
Citation: Iw. Althaus et al., THE QUINOLINE U-78036 IS A POTENT INHIBITOR OF HIV-1 REVERSE-TRANSCRIPTASE, The Journal of biological chemistry, 268(20), 1993, pp. 4875-4880
Authors:
ALTHAUS IW
CHOU JJ
GONZALES AJ
DEIBEL MR
CHOU KC
KEZDY FJ
ROMERO DL
PALMER JR
THOMAS RC
ARISTOFF PA
TARPLEY WG
REUSSER F
Citation: Iw. Althaus et al., KINETIC-STUDIES WITH THE NONNUCLEOSIDE HIV-1 REVERSE-TRANSCRIPTASE INHIBITOR-U-88204E, Biochemistry, 32(26), 1993, pp. 6548-6554