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Results: 1-25/43
Authors:
Shibata, D
Aaltonen, LA
Citation: D. Shibata et La. Aaltonen, Genetic predisposition and somatic diversification in tumor development and progression, ADV CANC R, 80, 2001, pp. 83-114
Authors:
Launonen, V
Vierimaa, O
Kiuru, M
Isola, J
Roth, S
Pukkala, E
Sistonen, P
Herva, R
Aaltonen, LA
Citation: V. Launonen et al., Inherited susceptibility to uterine leiomyomas and venal cell cancer, P NAS US, 98(6), 2001, pp. 3387-3392
Authors:
Lassus, H
Laitinen, MPE
Anttonen, M
Heikinheimo, M
Aaltonen, LA
Ritvos, O
Butzow, R
Citation: H. Lassus et al., Comparison of serous and mucinous ovarian carcinomas: Distinct pattern of allelic loss at distal 8p and expression of transcription factor GATA-4, LAB INV, 81(4), 2001, pp. 517-526
Authors:
Aaltonen, LM
Chen, RW
Roth, S
Makitie, AA
Rihkanen, H
Vaheri, A
Aaltonen, LA
Citation: Lm. Aaltonen et al., Role of TP53 P72R polymorphism in human papillomavirus associated premalignant laryngeal neoplasm, J MED GENET, 38(5), 2001, pp. 327-327
Authors:
Avizienyte, E
Launonen, V
Salovaara, R
Kiviluoto, T
Aaltonen, LA
Citation: E. Avizienyte et al., E-cadherin is not frequently mutated in hereditary gastric cancer, J MED GENET, 38(1), 2001, pp. 49-52
Authors:
Nakagawa, H
Nuovo, GJ
Zervos, EE
Martin, EW
Salovaara, R
Aaltonen, LA
de la Chapelle, A
Citation: H. Nakagawa et al., Age-related hypermethylation of the 5 ' region of MLH1 in normal colonic mucosa is associated with microsatellite-unstable colorectal cancer development, CANCER RES, 61(19), 2001, pp. 6991-6995
Authors:
Vahteristo, P
Tamminen, A
Karvinen, P
Eerola, H
Eklund, C
Aaltonen, LA
Blomqvist, C
Aittomaki, K
Nevanlinna, H
Citation: P. Vahteristo et al., p53, CHK2, and CHK1 genes in Finnish families with Li-Fraumeni syndrome: Further evidence of CHK2 in inherited cancer predisposition, CANCER RES, 61(15), 2001, pp. 5718-5722
Authors:
Vilkki, S
Tsao, JL
Loukola, A
Poyhonen, P
Vierimaa, O
Herva, R
Aaltonen, LA
Shibata, D
Citation: S. Vilkki et al., Extensive somatic microsatellite mutations in normal human tissue, CANCER RES, 61(11), 2001, pp. 4541-4544
Authors:
Loukola, A
Eklin, K
Laiho, P
Salovaara, R
Kristo, P
Jarvinen, H
Mecklin, JP
Launonen, V
Aaltonen, LA
Citation: A. Loukola et al., Microsatellite marker analysis in screening for hereditary nonpolyposis colorectal cancer (HNPCC), CANCER RES, 61(11), 2001, pp. 4545-4549
Authors:
Woodford-Richens, KL
Halford, S
Rowan, A
Bevan, S
Aaltonen, LA
Hasan, H
Bicknell, D
Bodmer, WF
Houlston, RS
Tomlinson, IPM
Citation: Kl. Woodford-richens et al., CDX2 mutations do not account for juvenile polyposis or Peutz-Jeghers syndrome and occur infrequently in sporadic colorectal cancers, BR J CANC, 84(10), 2001, pp. 1314-1316
Authors:
Woodford-Richens, KL
Rowan, AJ
Poulsom, R
Bevan, S
Salovaara, R
Aaltonen, LA
Houlston, RS
Wright, NA
Tomlinson, IPM
Citation: Kl. Woodford-richens et al., Comprehensive analysis of SMAD4 mutations and protein expression in juvenile polyposis - Evidence for a distinct genetic pathway and polyp morphologyin SMAD4 mutation carriers, AM J PATH, 159(4), 2001, pp. 1293-1300
Authors:
Kiuru, M
Launonen, V
Hietala, M
Aittomaki, K
Vierimaa, O
Salovaara, R
Arola, J
Pukkala, E
Sistonen, P
Herva, R
Aaltonen, LA
Citation: M. Kiuru et al., Familial cutaneous leiomyomatosis is a two-hit condition associated with renal cell cancer of characteristic histopathology, AM J PATH, 159(3), 2001, pp. 825-829
Authors:
Lassus, H
Salovaara, R
Aaltonen, LA
Butzow, R
Citation: H. Lassus et al., Allelic analysis of serous ovarian carcinoma reveals two putative tumor suppressor loci at 18q22-q23 distal to SMAD4, SMAD2, and DCC, AM J PATH, 159(1), 2001, pp. 35-42
Authors:
Zhou, XP
Woodford-Richens, K
Lehtonen, R
Kurose, K
Aldred, M
Hampel, H
Launonen, V
Virta, S
Pilarski, R
Salovaara, R
Bodmer, WF
Conrad, BA
Dunlop, M
Hodgson, SV
Iwama, T
Jarvinen, H
Kellokumpu, I
Kim, JC
Leggett, B
Markie, D
Mecklin, JP
Neale, K
Phillips, R
Piris, J
Rozen, P
Houlston, RS
Aaltonen, LA
Tomlinson, IPM
Eng, C
Citation: Xp. Zhou et al., Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes, AM J HU GEN, 69(4), 2001, pp. 704-711
Authors:
Aaltonen, LA
Citation: La. Aaltonen, Hereditary intestinal cancer, SEM CANC B, 10(4), 2000, pp. 289-298
Authors:
Esteller, M
Avizienyte, E
Corn, PG
Lothe, RA
Baylin, SB
Aaltonen, LA
Herman, JG
Citation: M. Esteller et al., Epigenetic inactivation of LKB1 in primary tumors associated with the Peutz-Jeghers syndrome, ONCOGENE, 19(1), 2000, pp. 164-168
Authors:
Salovaara,"de la Chapelle, A
Aaltonen, LA
Citation: A. Salovaara,"de La Chapelle et La. Aaltonen, Population-based molecular detection of hereditary nonpolyposis colorectalcancer (vol 18, pg 2193, 2000), J CL ONCOL, 18(19), 2000, pp. 3456-3456
Authors:
Salovaara, R
Loukola, A
Kristo, P
Kaariainen, H
Ahtola, H
Eskelinen, M
Harkonen, N
Julkunen, R
Kangas, E
Ojala, S
Tulikoura, J
Valkamo, E
Jarvinen, H
Mecklin, JP
Aaltonen, LA
de la Chapelle, A
Citation: R. Salovaara et al., Population-based molecular detection of hereditary nonpolyposis colorectalcancer, J CL ONCOL, 18(11), 2000, pp. 2193-2200
Authors:
Tsao, JL
Yatabe, Y
Salovaara, R
Jarvinen, HJ
Mecklin, JP
Aaltonen, LA
Tavare, S
Shibata, D
Citation: Jl. Tsao et al., Genetic reconstruction of individual colorectal tumor histories, P NAS US, 97(3), 2000, pp. 1236-1241
Authors:
Wheeler, JMD
Loukola, A
Aaltonen, LA
Mortensen, NJM
Bodmer, WF
Citation: Jmd. Wheeler et al., The role of hypermethylation of the hMLH1 promoter region in HNPCC versus MSI plus sporadic colorectal cancers, J MED GENET, 37(8), 2000, pp. 588-592
Authors:
Roth, S
Johansson, M
Loukola, A
Peltomaki, P
Jarvinen, H
Mecklin, JP
Aaltonen, LA
Citation: S. Roth et al., Mutation analysis of SMAD2, SMAD3, and SMAD4 genes in hereditary non-polyposis colorectal cancer, J MED GENET, 37(4), 2000, pp. 298-300
Authors:
Hemminki, A
Mecklin, JP
Jarvinen, H
Aaltonen, LA
Joensuu, H
Citation: A. Hemminki et al., Microsatellite instability is a favorable prognostic indicator in patientswith colorectal cancer receiving chemotherapy, GASTROENTY, 119(4), 2000, pp. 921-928
Authors:
Jarvinen, HJ
Aarnio, M
Mustonen, H
Aktan-Collan, K
Aaltonen, LA
Peltomaki, P
de la Chapelle, A
Mecklin, JP
Citation: Hj. Jarvinen et al., Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer, GASTROENTY, 118(5), 2000, pp. 829-834
Authors:
Launonen, V
Avizienyte, E
Loukola, A
Laiho, P
Salovaara, R
Jarvinen, H
Mecklin, JP
Oku, A
Shimane, M
Kim, HC
Kim, JC
Nezu, J
Aaltonen, LA
Citation: V. Launonen et al., No evidence of Peutz-Jeghers syndrome gene LKB1 involvement in left-sided colorectal carcinomas, CANCER RES, 60(3), 2000, pp. 546-548
Authors:
Roth, S
Laiho, P
Salovaara, R
Launonen, V
Aaltonen, LA
Citation: S. Roth et al., No SMAD4 hypermethylation in colorectal cancer, BR J CANC, 83(8), 2000, pp. 1015-1019