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Results: 1-25 | 26-27
Results: 1-25/27
The suppressors of cytokine signalling (SOCS)
Authors: Kile, BT Alexander, WS
Citation: Bt. Kile et Ws. Alexander, The suppressors of cytokine signalling (SOCS), CELL MOL L, 58(11), 2001, pp. 1627-1635
Negative regulators of cytokine signaling
Authors: Kile, BT Nicola, NA Alexander, WS
Citation: Bt. Kile et al., Negative regulators of cytokine signaling, INT J HEMAT, 73(3), 2001, pp. 292-298
SOCS1 deficiency results in accelerated mammary gland development and rescues lactation in prolactin receptor-deficient mice
Authors: Lindeman, GJ Wittlin, S Lada, H Naylor, MJ Santamaria, M Zhang, JG Starr, R Hilton, DJ Alexander, WS Ormandy, CJ Visvader, J
Citation: Gj. Lindeman et al., SOCS1 deficiency results in accelerated mammary gland development and rescues lactation in prolactin receptor-deficient mice, GENE DEV, 15(13), 2001, pp. 1631-1636
The multi-organ origin of interleukin-5 in the mouse
Authors: Ryan, PJ Willson, T Alexander, WS Di Rago, L Mifsud, S Metcalf, D
Citation: Pj. Ryan et al., The multi-organ origin of interleukin-5 in the mouse, LEUKEMIA, 15(8), 2001, pp. 1248-1255
Thrombopoietin signaling is required for in vivo expansion of IL-11-responsive hematopoietic progenitor cells in the steady state
Authors: Scott, CL Robb, L Nandurkar, HH Mansfield, R Alexander, WS Begley, CG
Citation: Cl. Scott et al., Thrombopoietin signaling is required for in vivo expansion of IL-11-responsive hematopoietic progenitor cells in the steady state, EXP HEMATOL, 29(2), 2001, pp. 138-145
Functional analysis of Asb-1 using genetic modification in mice
Authors: Kile, BT Metcalf, D Mifsud, S DiRago, L Nicola, NA Hilton, DJ Alexander, WS
Citation: Bt. Kile et al., Functional analysis of Asb-1 using genetic modification in mice, MOL CELL B, 21(18), 2001, pp. 6189-6197
The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo
Authors: Zhang, JG Metcalf, D Rakar, S Asimakis, M Greenhalgh, CJ Willson, TA Starr, R Nicholson, SE Carter, W Alexander, WS Hilton, DJ Nicola, NA
Citation: Jg. Zhang et al., The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo, P NAS US, 98(23), 2001, pp. 13261-13265
Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3
Authors: Roberts, AW Robb, L Rakar, S Hartley, L Cluse, L Nicola, NA Metcalf, D Hilton, DJ Alexander, WS
Citation: Aw. Roberts et al., Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3, P NAS US, 98(16), 2001, pp. 9324-9329
Production of colony-stimulating factors and IL-5 by organs from three types of mice with inflammatory disease due to loss of the suppressor of cytokine signaling-1
Authors: Metcalf, D Alexander, WS Ryan, PJ Mifsud, S Di Rago, L
Citation: D. Metcalf et al., Production of colony-stimulating factors and IL-5 by organs from three types of mice with inflammatory disease due to loss of the suppressor of cytokine signaling-1, J IMMUNOL, 167(8), 2001, pp. 4661-4667
Defective gp130-mediated signal transducer and activator of transcription (STAT) signaling results in degenerative joint disease, gastrointestinal ulceration, and failure of uterine implantation
Authors: Ernst, M Inglese, M Waring, P Campbell, IK Bao, SS Clay, FJ Alexander, WS Wicks, IP Tarlinton, DM Novak, U Heath, JK Dunn, AR
Citation: M. Ernst et al., Defective gp130-mediated signal transducer and activator of transcription (STAT) signaling results in degenerative joint disease, gastrointestinal ulceration, and failure of uterine implantation, J EXP MED, 194(2), 2001, pp. 189-203
Suppressor of cytokine signaling-1 attenuates the duration of interferon gamma signal transduction in vitro and in vivo
Authors: Brysha, M Zhang, JG Bertolino, P Corbin, JE Alexander, WS Nicola, NA Hilton, DJ Starr, R
Citation: M. Brysha et al., Suppressor of cytokine signaling-1 attenuates the duration of interferon gamma signal transduction in vitro and in vivo, J BIOL CHEM, 276(25), 2001, pp. 22086-22089
Neutralization of interferon-gamma in neonatal SOCS1(-/-) mice prevents fatty degeneration of the liver but not subsequent fatal inflammatory disease
Authors: Bullen, DVR Darwiche, R Metcalf, D Handman, E Alexander, WS
Citation: Dvr. Bullen et al., Neutralization of interferon-gamma in neonatal SOCS1(-/-) mice prevents fatty degeneration of the liver but not subsequent fatal inflammatory disease, IMMUNOLOGY, 104(1), 2001, pp. 92-98
Cloning and characterization of the genes encoding the ankyrin repeat and SOCS box-containing proteins Asb-1, Asb-2, Asb-3 and Asb-4
Authors: Kile, BT Viney, EM Willson, TA Brodnicki, TC Cancilla, MR Herlihy, AS Croker, BA Baca, M Nicola, NA Hilton, DJ Alexander, WS
Citation: Bt. Kile et al., Cloning and characterization of the genes encoding the ankyrin repeat and SOCS box-containing proteins Asb-1, Asb-2, Asb-3 and Asb-4, GENE, 258(1-2), 2000, pp. 31-41
Granulocyte-macrophage colony-stimulating factor is not responsible for residual thrombopoiesis in mpl null mice
Authors: Scott, CL Robb, L Mansfield, R Alexander, WS Begley, CG
Citation: Cl. Scott et al., Granulocyte-macrophage colony-stimulating factor is not responsible for residual thrombopoiesis in mpl null mice, EXP HEMATOL, 28(9), 2000, pp. 1001-1007
Gigantism in mice lacking suppressor of cytokine signalling-2
Authors: Metcalf, D Greenhalgh, CJ Viney, E Willson, TA Starr, R Nicola, NA Hilton, DJ Alexander, WS
Citation: D. Metcalf et al., Gigantism in mice lacking suppressor of cytokine signalling-2, NATURE, 405(6790), 2000, pp. 1069-1073
The development of fatal myocarditis and polymyositis in mice heterozygousfor IFN-gamma and lacking the SOCS-1 gene
Authors: Metcalf, D Di Rago, L Mifsud, S Hartley, L Alexander, WS
Citation: D. Metcalf et al., The development of fatal myocarditis and polymyositis in mice heterozygousfor IFN-gamma and lacking the SOCS-1 gene, P NAS US, 97(16), 2000, pp. 9174-9179
The residual megakaryocyte and platelet production in c-Mpl-deficient miceis not dependent on the actions of interleukin-6, interleukin-11, or leukemia inhibitory factor
Authors: Gainsford, T Nandurkar, H Metcalf, D Robb, L Begley, CG Alexander, WS
Citation: T. Gainsford et al., The residual megakaryocyte and platelet production in c-Mpl-deficient miceis not dependent on the actions of interleukin-6, interleukin-11, or leukemia inhibitory factor, BLOOD, 95(2), 2000, pp. 528-534
Thrombopoietin and the c-Mpl receptor: insights from gene targeting
Authors: Alexander, WS
Citation: Ws. Alexander, Thrombopoietin and the c-Mpl receptor: insights from gene targeting, INT J BIO C, 31(10), 1999, pp. 1027-1035
Suckling defect in mice lacking the soluble haemopoietin receptor NR6
Authors: Alexander, WS Rakar, S Robb, L Farley, A Willson, TA Zhang, JG Hartley, L Kikuchi, Y Kojima, T Nomura, H Hasegawa, M Maeda, M Fabri, L Jachno, K Nash, A Metcalf, D Nicola, NA Hilton, DJ
Citation: Ws. Alexander et al., Suckling defect in mice lacking the soluble haemopoietin receptor NR6, CURR BIOL, 9(11), 1999, pp. 605-608
Thrombopoietin
Authors: Alexander, WS
Citation: Ws. Alexander, Thrombopoietin, GROW FACTOR, 17(1), 1999, pp. 13-24
Aberrant hematopoiesis in mice with inactivation of the gene encoding SOCS-1
Authors: Metcalf, D Alexander, WS Elefanty, AG Nicola, NA Hilton, DJ Starr, R Mifsud, S Di Rago, L
Citation: D. Metcalf et al., Aberrant hematopoiesis in mice with inactivation of the gene encoding SOCS-1, LEUKEMIA, 13(6), 1999, pp. 926-934
Suppressors of cytokine signaling (SOCS): negative regulators of signal transduction
Authors: Alexander, WS Starr, R Metcalf, D Nicholson, SE Farley, A Elefanty, AG Brysha, M Kile, BT Richardson, R Baca, M Zhang, JG Willson, TA Viney, EM Sprigg, NS Rakar, S Corbin, J Mifsud, S DiRago, L Cary, D Nicola, NA Hilton, DJ
Citation: Ws. Alexander et al., Suppressors of cytokine signaling (SOCS): negative regulators of signal transduction, J LEUK BIOL, 66(4), 1999, pp. 588-592
Mutational analyses of the SOCS proteins suggest a dual domain requirementbut distinct mechanisms for inhibition of LIF and IL-6 signal transduction
Authors: Nicholson, SE Willson, TA Farley, A Starr, R Zhang, JG Baca, M Alexander, WS Metcalf, D Hilton, DJ Nicola, NA
Citation: Se. Nicholson et al., Mutational analyses of the SOCS proteins suggest a dual domain requirementbut distinct mechanisms for inhibition of LIF and IL-6 signal transduction, EMBO J, 18(2), 1999, pp. 375-385
SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine
Authors: Alexander, WS Starr, R Fenner, JE Scott, GL Handman, E Sprigg, NS Corbin, JE Cornish, AL Darwiche, R Owczarek, CM Kay, TWH Nicola, NA Hertzog, PJ Metcalf, D Hilton, DJ
Citation: Ws. Alexander et al., SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine, CELL, 98(5), 1999, pp. 597-608
The conserved SOCS box motif in suppressors of cytokine signaling binds toelongins B and C and may couple bound proteins to proteasomal degradation
Authors: Zhang, JG Farley, A Nicholson, SE Willson, TA Zugaro, LM Simpson, RJ Moritz, RL Cary, D Richardson, R Hausmann, G Kile, BJ Kent, SBH Alexander, WS Metcalf, D Hilton, DJ Nicola, NA Baca, M
Citation: Jg. Zhang et al., The conserved SOCS box motif in suppressors of cytokine signaling binds toelongins B and C and may couple bound proteins to proteasomal degradation, P NAS US, 96(5), 1999, pp. 2071-2076
Risultati: 1-25 | 26-27