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Results: 1-10 |
Results: 10
Synthesis and analysis of polyethylene glycol linked P-glycoprotein-specific homodimers based on (-)-stipiamide
Authors: Andrus, MB Turner, TM Updegraff, EP Sauna, ZE Ambudkar, SV
Citation: Mb. Andrus et al., Synthesis and analysis of polyethylene glycol linked P-glycoprotein-specific homodimers based on (-)-stipiamide, TETRAHEDR L, 42(23), 2001, pp. 3819-3822
Evidence for the vectorial nature of drug (substrate)-stimulated ATP hydrolysis by human P-glycoprotein
Authors: Sauna, ZE Smith, MM Muller, M Ambudkar, SV
Citation: Ze. Sauna et al., Evidence for the vectorial nature of drug (substrate)-stimulated ATP hydrolysis by human P-glycoprotein, J BIOL CHEM, 276(36), 2001, pp. 33301-33304
Functionally similar vanadate-induced 8-azidoadenosine 5 '-[alpha-P-32]diphosphate-trapped transition state intermediates of human P-glycoprotein aregenerated in the absence and presence of ATP hydrolysis
Authors: Sauna, ZE Smith, MM Muller, M Ambudkar, SV
Citation: Ze. Sauna et al., Functionally similar vanadate-induced 8-azidoadenosine 5 '-[alpha-P-32]diphosphate-trapped transition state intermediates of human P-glycoprotein aregenerated in the absence and presence of ATP hydrolysis, J BIOL CHEM, 276(24), 2001, pp. 21199-21208
Characterization of the catalytic cycle of ATP hydrolysis by human P-glycoprotein - The two ATP hydrolysis events in a single catalytic cycle are kinetically similar but affect different functional outcomes
Authors: Sauna, ZE Ambudkar, SV
Citation: Ze. Sauna et Sv. Ambudkar, Characterization of the catalytic cycle of ATP hydrolysis by human P-glycoprotein - The two ATP hydrolysis events in a single catalytic cycle are kinetically similar but affect different functional outcomes, J BIOL CHEM, 276(15), 2001, pp. 11653-11661
Correlation between steady-state ATP hydrolysis and vanadate-induced ADP trapping in human P-glycoprotein - Evidence for ADP release as the rate-limiting step in the catalytic cycle and its modulation by substrates
Authors: Kerr, KM Sauna, ZE Ambudkar, SV
Citation: Km. Kerr et al., Correlation between steady-state ATP hydrolysis and vanadate-induced ADP trapping in human P-glycoprotein - Evidence for ADP release as the rate-limiting step in the catalytic cycle and its modulation by substrates, J BIOL CHEM, 276(12), 2001, pp. 8657-8664
Synthesis and preliminary analysis of a P-glycoprotein-specific [H-3]-benzophenone photoaffinity label based on (-)-stipiamide
Authors: Andrus, MB Turner, TM Sauna, ZE Ambudkar, SV
Citation: Mb. Andrus et al., Synthesis and preliminary analysis of a P-glycoprotein-specific [H-3]-benzophenone photoaffinity label based on (-)-stipiamide, BIOORG MED, 10(20), 2000, pp. 2275-2278
Evidence for a requirement for ATP hydrolysis at two distinct steps duringa single turnover of the catalytic cycle of human P-glycoprotein
Authors: Sauna, ZE Ambudkar, SV
Citation: Ze. Sauna et Sv. Ambudkar, Evidence for a requirement for ATP hydrolysis at two distinct steps duringa single turnover of the catalytic cycle of human P-glycoprotein, P NAS US, 97(6), 2000, pp. 2515-2520
The synthesis and evaluation of a solution phase indexed combinatorial library of non-natural polyenes for reversal of p-glycoprotein mediated multidrug resistance
Authors: Andrus, MB Turner, TM Sauna, ZE Ambudkar, SV
Citation: Mb. Andrus et al., The synthesis and evaluation of a solution phase indexed combinatorial library of non-natural polyenes for reversal of p-glycoprotein mediated multidrug resistance, J ORG CHEM, 65(16), 2000, pp. 4973-4983
Functional characterization of glycosylation-deficient human P-glycoprotein using a vaccinia virus expression system
Authors: Gribar, JJ Ramachandra, M Hrycyna, CA Dey, S Ambudkar, SV
Citation: Jj. Gribar et al., Functional characterization of glycosylation-deficient human P-glycoprotein using a vaccinia virus expression system, J MEMBR BIO, 173(3), 2000, pp. 203-214
Biochemical, cellular, and pharmacological aspects of the multidrug transporter
Authors: Ambudkar, SV Dey, S Hrycyna, CA Ramachandra, M Pastan, I Gottesman, MM
Citation: Sv. Ambudkar et al., Biochemical, cellular, and pharmacological aspects of the multidrug transporter, ANN R PHARM, 39, 1999, pp. 361-398
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