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Results: 16
In vitro high throughput screening of compounds for favorable metabolic properties in drug discovery
Authors:
Masimirembwa, CM
Thompson, R
Andersson, TB
Citation: Cm. Masimirembwa et al., In vitro high throughput screening of compounds for favorable metabolic properties in drug discovery, COMB CHEM H, 4(3), 2001, pp. 245-263
Authors:
Sadar, MD
Andersson, TB
Citation: Md. Sadar et Tb. Andersson, Regulation of cytochrome P450 in a primary culture of rainbow trout hepatocytes, IN VITRO-AN, 37(3), 2001, pp. 180-184
Authors:
Blom, S
Forlin, L
Andersson, TB
Citation: S. Blom et al., Characterisation of head kidney and liver microsomal 17-hydroxyprogesterone 21-hydroxylase activity in rainbow trout (Oncorhynchus mykiss) and the lack of regulatory effects of ACTH, FISH PHYS B, 24(1), 2001, pp. 1-8
Authors:
Andersson, TB
Sjoberg, H
Hoffmann, KJ
Boobis, AR
Watts, P
Edwards, RJ
Lake, BG
Price, RJ
Renwick, AB
Gomez-Lechon, MJ
Castell, JV
Ingelman-Sundberg, M
Hidestrand, M
Goldfarb, PS
Lewis, DFV
Corcos, L
Guillouzo, A
Taavitsainen, P
Pelkonen, O
Citation: Tb. Andersson et al., An assessment of human liver-derived in vitro systems to predict the in vivo metabolism and clearance of almokalant, DRUG META D, 29(5), 2001, pp. 712-720
Authors:
Afzelius, L
Zamora, I
Ridderstrom, M
Andersson, TB
Karlen, A
Masimirembwa, CM
Citation: L. Afzelius et al., Competitive CYP2C9 inhibitors: Enzyme inhibition studies, protein homologymodeling, and three-dimensional quantitative structure-activity relationship analysis, MOLEC PHARM, 59(4), 2001, pp. 909-919
Authors:
Ridderstrom, M
Zamora, I
Fjellstrom, O
Andersson, TB
Citation: M. Ridderstrom et al., Analysis of selective regions in the active sites of human cytochromes P450, 2CS, 2C9, 2C18, and 2C19 homology models using GRID/CPCA, J MED CHEM, 44(24), 2001, pp. 4072-4081
Authors:
Westlind, A
Malmebo, S
Johansson, I
Otter, C
Andersson, TB
Ingelman-Sundberg, M
Oscarson, M
Citation: A. Westlind et al., Cloning and tissue distribution of a novel human cytochrome P450 of the CYP3A subfamily, CYP3A43, BIOC BIOP R, 281(5), 2001, pp. 1349-1355
Authors:
Neuhoff, S
Langguth, P
Dressler, C
Andersson, TB
Regardh, CG
Spahn-Langguth, H
Citation: S. Neuhoff et al., Affinities at the verapamil binding site of MDR1-encoded P-glycoprotein: drugs and analogs, stereoisomers and metabolites, INT J CL PH, 38(4), 2000, pp. 168-179
Authors:
Blom, S
Andersson, TB
Forlin, L
Citation: S. Blom et al., Effects of food deprivation and handling stress on head kidney 17 alpha-hydroxyprogesterone 21-hydroxylase activity, plasma cortisol and the activities of liver detoxification enzymes in rainbow trout, AQUAT TOX, 48(2-3), 2000, pp. 265-274
Authors:
Abelo, A
Andersson, TB
Antonsson, M
Naudot, AK
Skanberg, I
Weidolf, L
Citation: A. Abelo et al., Stereoselective metabolism of omeprazole by human cytochrome P450 enzymes, DRUG META D, 28(8), 2000, pp. 966-972
Authors:
Abelo, A
Andersson, TB
Bredberg, U
Skanberg, I
Weidolf, L
Citation: A. Abelo et al., Stereoselective metabolism by human liver CYP enzymes of a substituted benzimidazole, DRUG META D, 28(1), 2000, pp. 58-64
Authors:
Pesonen, M
Korkalainen, M
Laitinen, JT
Andersson, TB
Vakkuri, O
Citation: M. Pesonen et al., 2,3,7,8-tetrachlorodibenzo-p-dioxin alters melatonin metabolism in fish hepatocytes, CHEM-BIO IN, 126(3), 2000, pp. 227-240
Authors:
Pesonen, M
Andersson, TB
Sorri, V
Korkalainen, M
Citation: M. Pesonen et al., Biochemical and ultrastructural changes in the liver of Baltic salmon sac fry suffering from high mortality (M74), ENV TOX CH, 18(5), 1999, pp. 1007-1013
Authors:
Masimirembwa, CM
Otter, C
Berg, M
Jonsson, M
Leidvik, B
Jonsson, E
Johansson, T
Backman, A
Edlund, A
Andersson, TB
Citation: Cm. Masimirembwa et al., Heterologous expression and kinetic characterization of human cytochromes P-450: Validation of a pharmaceutical tool for drug metabolism research, DRUG META D, 27(10), 1999, pp. 1117-1122
Authors:
Doppenschmitt, S
Langguth, P
Regardh, CG
Andersson, TB
Hilgendorf, C
Spahn-Langguth, H
Citation: S. Doppenschmitt et al., Characterization of binding properties to human P-glycoprotein: Development of a [H-3]verapamil radioligand-binding assay, J PHARM EXP, 288(1), 1999, pp. 348-357
Authors:
Westlind, A
Lofberg, L
Tindberg, N
Andersson, TB
Ingelman-Sundberg, M
Citation: A. Westlind et al., Interindividual differences in hepatic expression of CYP3A4: Relationship to genetic polymorphism in the 5 '-upstream regulatory region, BIOC BIOP R, 259(1), 1999, pp. 201-205
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