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Results: 1-11 |
Results: 11
Design and synthesis of a series of (2R)-N-4-hydroxy-2-(3-hydroxybenzyl)-N-1-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]butanediamide derivatives as potent, selective, and orally bioavailable aggrecanase inhibitors
Authors: Yao, WQ Wasserman, ZR Chao, M Reddy, G Shi, E Liu, RQ Covington, MB Arner, EC Pratta, MA Tortorella, M Magolda, RL Newton, R Qian, MX Ribadeneira, MD Christ, D Wexler, RR Decicco, CP
Citation: Wq. Yao et al., Design and synthesis of a series of (2R)-N-4-hydroxy-2-(3-hydroxybenzyl)-N-1-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]butanediamide derivatives as potent, selective, and orally bioavailable aggrecanase inhibitors, J MED CHEM, 44(21), 2001, pp. 3347-3350
Host metalloproteinases in Lyme arthritis
Authors: Hu, LT Eskildsen, MA Masgala, C Steere, AC Arner, EC Pratta, MA Grodzinsky, AJ Loening, A Perides, G
Citation: Lt. Hu et al., Host metalloproteinases in Lyme arthritis, ARTH RHEUM, 44(6), 2001, pp. 1401-1410
Age-related changes in aggrecan glycosylation affect cleavage by aggrecanase
Authors: Pratta, MA Tortorella, MD Arner, EC
Citation: Ma. Pratta et al., Age-related changes in aggrecan glycosylation affect cleavage by aggrecanase, J BIOL CHEM, 275(50), 2000, pp. 39096-39102
Brain-enriched hyaluronan binding (BEHAB)/brevican cleavage in a glioma cell line is mediated by a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) family member
Authors: Matthews, RT Gary, SC Zerillo, C Pratta, M Solomon, K Arner, EC Hockfield, S
Citation: Rt. Matthews et al., Brain-enriched hyaluronan binding (BEHAB)/brevican cleavage in a glioma cell line is mediated by a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) family member, J BIOL CHEM, 275(30), 2000, pp. 22695-22703
Chondrocyte extracellular matrix synthesis and turnover are influenced by static compression in a new alginate disk culture system
Authors: Ragan, PM Chin, VI Hung, HHK Masuda, K Thonar, EJMA Arner, EC Grodzinsky, AJ Sandy, JD
Citation: Pm. Ragan et al., Chondrocyte extracellular matrix synthesis and turnover are influenced by static compression in a new alginate disk culture system, ARCH BIOCH, 383(2), 2000, pp. 256-264
Macrocyclic hydroxamate inhibitors of matrix metalloproteinases and TNF-alpha production
Authors: Cherney, RJ Wang, L Meyer, DT Xue, CB Arner, EC Copeland, RA Covington, MB Hardman, KD Wasserman, ZR Jaffee, BD Decicco, CP
Citation: Rj. Cherney et al., Macrocyclic hydroxamate inhibitors of matrix metalloproteinases and TNF-alpha production, BIOORG MED, 9(9), 1999, pp. 1279-1284
P-1, P-2 '-linked macrocyclic amine derivatives as matrix metalloproteinase inhibitors
Authors: Duan, JJW Chen, LH Xue, CB Wasserman, ZR Hardman, KD Covington, MB Copeland, RR Arner, EC Decicco, CP
Citation: Jjw. Duan et al., P-1, P-2 '-linked macrocyclic amine derivatives as matrix metalloproteinase inhibitors, BIOORG MED, 9(10), 1999, pp. 1453-1458
Purification and cloning of aggrecanase-1: A member of the ADAMTS family of proteins
Authors: Tortorella, MD Burn, TC Pratta, MA Abbaszade, I Hollis, JM Liu, R Rosenfeld, SA Copeland, RA Decicco, CP Wynn, R Rockwell, A Yang, F Duke, JL Solomon, K George, H Bruckner, R Nagase, H Itoh, Y Ellis, DM Ross, H Wiswall, BH Murphy, K Hillman, MC Hollis, GF Newton, RC Magolda, RL Trzaskos, JM Arner, EC
Citation: Md. Tortorella et al., Purification and cloning of aggrecanase-1: A member of the ADAMTS family of proteins, SCIENCE, 284(5420), 1999, pp. 1664-1666
Recombinant human aggrecan G1-G2 exhibits native binding properties and substrate specificity for matrix metalloproteinases and aggrecanase
Authors: Mercuri, FA Doege, KJ Arner, EC Pratta, MA Last, K Fosang, AJ
Citation: Fa. Mercuri et al., Recombinant human aggrecan G1-G2 exhibits native binding properties and substrate specificity for matrix metalloproteinases and aggrecanase, J BIOL CHEM, 274(45), 1999, pp. 32387-32395
Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family
Authors: Abbaszade, I Liu, RQ Yang, F Rosenfeld, SA Ross, OH Link, JR Ellis, DM Tortorella, MD Pratta, MA Hollis, JM Wynn, R Duke, JL George, HJ Hillman, MC Murphy, K Wiswall, BH Copeland, RA Decicco, CP Bruckner, R Nagase, H Itoh, Y Newton, RC Magolda, RL Trzaskos, JM Hollis, GF Arner, EC Burn, TC
Citation: I. Abbaszade et al., Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family, J BIOL CHEM, 274(33), 1999, pp. 23443-23450
Generation and characterization of aggrecanase - A soluble, cartilage-derived aggrecan-degrading activity
Authors: Arner, EC Pratta, MA Trzaskos, JM Decicco, CP Tortorella, MD
Citation: Ec. Arner et al., Generation and characterization of aggrecanase - A soluble, cartilage-derived aggrecan-degrading activity, J BIOL CHEM, 274(10), 1999, pp. 6594-6601
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