Authors:
OLMSTED RA
SLADE DE
KOPTA LA
POPPE SM
POEL TJ
NEWPORT SW
RANK KB
BILES C
MORGE RA
DUEWEKE TJ
YAGI Y
ROMERO DL
THOMAS RC
SHARMA SK
TARPLEY WG
Citation: Ra. Olmsted et al., (ALKYLAMINO)PIPERIDINE BIS(HETEROARYL)PIPERIZINE ANALOGS ARE POTENT, BROAD-SPECTRUM NONNUCLEOSIDE REVERSE-TRANSCRIPTASE INHIBITORS OF DRUG-RESISTANT ISOLATES OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 (HIV-1) AND SELECT FOR DRUG-RESISTANT VARIANTS OF HIV-1(IIIB) WITH REDUCED REPLICATION PHENOTYPES, Journal of virology, 70(6), 1996, pp. 3698-3705
Authors:
GENIN MJ
POEL TJ
YAGI Y
BILES C
ALTHAUS I
KEISER BJ
KOPTA LA
FRIIS JM
REUSSER F
ADAMS WJ
OLMSTED RA
VOORMAN RL
THOMAS RC
ROMERO DL
Citation: Mj. Genin et al., SYNTHESIS AND BIOACTIVITY OF NOVEL BIS (HETEROARYL)PIPERAZINE (BHAP) REVERSE-TRANSCRIPTASE INHIBITORS - STRUCTURE-ACTIVITY-RELATIONSHIPS AND INCREASED METABOLIC STABILITY OF NOVEL SUBSTITUTED PYRIDINE ANALOGS, Journal of medicinal chemistry, 39(26), 1996, pp. 5267-5275
Authors:
THAISRIVONGS S
ROMERO DL
TOMMASI RA
JANAKIRAMAN MN
STROHBACH JW
TURNER SR
BILES C
MORGE RR
JOHNSON PD
ARISTOFF PA
TOMICH PK
LYNN JC
HORNG MM
CHONG KT
HINSHAW RR
HOWE WJ
FINZEL BC
WATENPAUGH KD
Citation: S. Thaisrivongs et al., STRUCTURE-BASED DESIGN OF HIV PROTEASE INHIBITORS - 5,6-DIHYDRO-4-HYDROXY-2-PYRONES AS EFFECTIVE, NONPEPTIDIC INHIBITORS, Journal of medicinal chemistry, 39(23), 1996, pp. 4630-4642
Authors:
ROMERO DL
OLMSTED RA
POEL TJ
MORGE RA
BILES C
KEISER BJ
KOPTA LA
FRIIS JM
HOSLEY JD
STEFANSKI KJ
WISHKA DG
EVANS DB
MORRIS J
STEHLE RG
SHARMA SK
YAGI Y
VOORMAN RL
ADAMS WJ
TARPLEY WG
THOMAS RC
Citation: Dl. Romero et al., TARGETING DELAVIRDINE ATEVIRDINE RESISTANT HIV-1 - IDENTIFICATION OF (ALKYLAMINO)PIPERIDINE-CONTAINING BIS(HETEROARYL)PIPERAZINES AS BROAD-SPECTRUM HIV-1 REVERSE-TRANSCRIPTASE INHIBITORS/, Journal of medicinal chemistry, 39(19), 1996, pp. 3769-3789
Authors:
ROMERO DL
MORGE RA
BILES C
BERRIOSPENA TN
MAY PD
PALMER JR
JOHNSON PD
SMITH HW
BUSSO M
TAN CK
VOORMAN RL
REUSSER F
ALTHAUS IW
DOWNEY KM
SO AG
RESNICK L
TARPLEY WG
ARISTOFF PA
Citation: Dl. Romero et al., DISCOVERY, SYNTHESIS, AND BIOACTIVITY OF BIS(HETEROARYL)PIPERAZINES .1. A NOVEL CLASS OF NONNUCLEOSIDE HIV-1 REVERSE-TRANSCRIPTASE INHIBITORS, Journal of medicinal chemistry, 37(7), 1994, pp. 999-1014
Authors:
ROMERO DL
MORGE RA
GENIN MJ
BILES C
BUSSO M
RESNICK L
ALTHAUS IW
REUSSER F
THOMAS RC
TARPLEY WG
Citation: Dl. Romero et al., BIS(HETEROARYL)PIPERAZINE (BHAP) REVERSE-TRANSCRIPTASE INHIBITORS - STRUCTURE-ACTIVITY-RELATIONSHIPS OF NOVEL SUBSTITUTED INDOLE ANALOGS AND THE IDENTIFICATION OF ]-4-[3-[(1-METHYLETHYL)AMINO]-PYRIDINYL]PIPERAZINE MONOMETHANESULFONATE (U-90152S), A 2ND-GENERATION CLINICAL CANDIDATE, Journal of medicinal chemistry, 36(10), 1993, pp. 1505-1508