Authors:
BREWSTER M
LEWIS EJ
WILSON KL
GREENHAM AK
BOTTOMLEY KMK
Citation: M. Brewster et al., RO-32-3555, AN ORALLY-ACTIVE COLLAGENASE SELECTIVE INHIBITOR, PREVENTS STRUCTURAL DAMAGE IN THE STR ORT MOUSE MODEL OF OSTEOARTHRITIS/, Arthritis and rheumatism, 41(9), 1998, pp. 1639-1644
Authors:
BROADHURST MJ
BROWN PA
LAWTON G
BALLANTYNE N
BORKAKOTI N
BOTTOMLEY KMK
COOPER MI
EATHERTON AJ
KILFORD IR
MALSHER PJ
NIXON JS
LEWIS EJ
SUTTON BM
JOHNSON WH
Citation: Mj. Broadhurst et al., DESIGN AND SYNTHESIS OF THE CARTILAGE PROTECTIVE AGENT (CPA, RO32-3555), Bioorganic & medicinal chemistry letters, 7(17), 1997, pp. 2299-2302
Authors:
LEWIS EJ
BISHOP J
BOTTOMLEY KMK
BRADSHAW D
BREWSTER M
BROADHURST MJ
BROWN PA
BUDD JM
ELLIOTT L
GREENHAM AK
JOHNSON WH
NIXON JS
ROSE F
SUTTON B
WILSON K
Citation: Ej. Lewis et al., RO-32-3555, AN ORALLY-ACTIVE COLLAGENASE INHIBITOR, PREVENTS CARTILAGE BREAKDOWN IN-VITRO AND IN-VIVO, British Journal of Pharmacology, 121(3), 1997, pp. 540-546
Authors:
HILL PA
DOCHERTY AJP
BOTTOMLEY KMK
OCONNELL JP
MORPHY JR
REYNOLDS JJ
MEIKLE MC
Citation: Pa. Hill et al., INHIBITION OF BONE-RESORPTION IN-VITRO BY SELECTIVE INHIBITORS OF GELATINASE AND COLLAGENASE, Biochemical journal, 308, 1995, pp. 167-175