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Results: 1-14 |
Results: 14
ANALYSIS OF THE MECHANISM OF ACTION OF ANTI-HUMAN INTERLEUKIN-6 AND ANTI-HUMAN INTERLEUKIN-6 RECEPTOR-NEUTRALIZING MONOCLONAL-ANTIBODIES
Authors: KALAI M MONTEROJULIAN FA BRAKENHOFF JPJ FONTAINE V DEWIT L WOLLMER A BRAILLY H CONTENT J GROTZINGER J
Citation: M. Kalai et al., ANALYSIS OF THE MECHANISM OF ACTION OF ANTI-HUMAN INTERLEUKIN-6 AND ANTI-HUMAN INTERLEUKIN-6 RECEPTOR-NEUTRALIZING MONOCLONAL-ANTIBODIES, European journal of biochemistry, 249(3), 1997, pp. 690-700
IDENTIFICATION OF SINGLE AMINO-ACID-RESIDUES OF HUMAN IL-6 INVOLVED IN RECEPTOR-BINDING AND SIGNAL INITIATION
Authors: EHLERS M GROTZINGER J FISCHER M BOS HK BRAKENHOFF JPJ ROSEJOHN S
Citation: M. Ehlers et al., IDENTIFICATION OF SINGLE AMINO-ACID-RESIDUES OF HUMAN IL-6 INVOLVED IN RECEPTOR-BINDING AND SIGNAL INITIATION, Journal of interferon & cytokine research, 16(8), 1996, pp. 569-576
PURIFICATION AND CHARACTERIZATION OF THE SOLUBLE INTERLEUKIN-6 RECEPTOR FROM HUMAN PLASMA AND IDENTIFICATION OF AN ISOFORM GENERATED THROUGH ALTERNATIVE SPLICING
Authors: KEUL R KOHNE C MULLERNEWEN G HEMMANN U MULLERESTERL W WIJDENES J BRAKENHOFF JPJ HART MHL HEINRICH PC MATERN S
Citation: R. Keul et al., PURIFICATION AND CHARACTERIZATION OF THE SOLUBLE INTERLEUKIN-6 RECEPTOR FROM HUMAN PLASMA AND IDENTIFICATION OF AN ISOFORM GENERATED THROUGH ALTERNATIVE SPLICING, Hepatology, 24(4), 1996, pp. 24-24
IDENTIFICATION OF RESIDUES IN THE PUTATIVE 5TH HELICAL REGION OF HUMAN INTERLEUKIN-6, IMPORTANT FOR ACTIVATION OF THE IL-6 SIGNAL TRANSDUCER, GP130
Authors: BRAKENHOFF JPJ BOS HK GROTZINGER J ROSEJOHN S AARDEN LA
Citation: Jpj. Brakenhoff et al., IDENTIFICATION OF RESIDUES IN THE PUTATIVE 5TH HELICAL REGION OF HUMAN INTERLEUKIN-6, IMPORTANT FOR ACTIVATION OF THE IL-6 SIGNAL TRANSDUCER, GP130, FEBS letters, 395(2-3), 1996, pp. 235-240
PURIFICATION AND CHARACTERIZATION OF THE SOLUBLE INTERLEUKIN-6 RECEPTOR FROM HUMAN PLASMA AND IDENTIFICATION OF AN ISOFORM GENERATED THROUGH ALTERNATIVE SPLICING
Authors: MULLERNEWEN G KOHNE C KEUL R HEMMANN U MULLERESTERL W WIJDENES J BRAKENHOFF JPJ HART MHL HEINRICH PC
Citation: G. Mullernewen et al., PURIFICATION AND CHARACTERIZATION OF THE SOLUBLE INTERLEUKIN-6 RECEPTOR FROM HUMAN PLASMA AND IDENTIFICATION OF AN ISOFORM GENERATED THROUGH ALTERNATIVE SPLICING, European journal of biochemistry, 236(3), 1996, pp. 837-842
FUNCTIONAL DISTINCTION OF 2 REGIONS OF HUMAN INTERLEUKIN-6 IMPORTANT FOR SIGNAL-TRANSDUCTION VIA GP130
Authors: DEHON FD TENBOEKEL E HERRMAN J CLEMENT C EHLERS M TAGA T YASUKAWA K OHSUGI Y KISHIMOTO T ROSEJOHN S WIJDENES J KASTELEIN R AARDEN LA BRAKENHOFF JPJ
Citation: Fd. Dehon et al., FUNCTIONAL DISTINCTION OF 2 REGIONS OF HUMAN INTERLEUKIN-6 IMPORTANT FOR SIGNAL-TRANSDUCTION VIA GP130, Cytokine, 7(5), 1995, pp. 398-407
COMBINING 2 MUTATIONS OF HUMAN INTERLEUKIN-6 THAT AFFECT GP130 ACTIVATION RESULTS IN A POTENT INTERLEUKIN-6 RECEPTOR ANTAGONIST ON HUMAN MYELOMA CELLS
Authors: EHLERS M DEHON FD BOS HK HORSTEN U KURAPKAT G VANDELEUR HS GROTZINGER J WOLLMER A BRAKENHOFF JPJ ROSEJOHN S
Citation: M. Ehlers et al., COMBINING 2 MUTATIONS OF HUMAN INTERLEUKIN-6 THAT AFFECT GP130 ACTIVATION RESULTS IN A POTENT INTERLEUKIN-6 RECEPTOR ANTAGONIST ON HUMAN MYELOMA CELLS, The Journal of biological chemistry, 270(14), 1995, pp. 8158-8163
LEUCINE-58 IN THE PUTATIVE 5TH HELICAL REGION OF HUMAN INTERLEUKIN (IL)-6 IS IMPORTANT FOR ACTIVATION OF THE IL-6 SIGNAL TRANSDUCER, GP130
Authors: DEHEN FD BOS HK EBELING SB GROTZINGER J KURAPKAT G ROSEJOHN S AARDEN LA BRAKENHOFF JPJ
Citation: Fd. Dehen et al., LEUCINE-58 IN THE PUTATIVE 5TH HELICAL REGION OF HUMAN INTERLEUKIN (IL)-6 IS IMPORTANT FOR ACTIVATION OF THE IL-6 SIGNAL TRANSDUCER, GP130, FEBS letters, 369(2-3), 1995, pp. 187-191
SOLUBLE HUMAN INTERLEUKIN-6 RECEPTOR - EXPRESSION IN INSECT CELLS, PURIFICATION AND CHARACTERIZATION
Authors: WEIERGRABER O HEMMANN U KUSTER A MULLERNEWEN G SCHNEIDER J ROSEJOHN S KURSCHAT P BRAKENHOFF JPJ HART MHL STABEL S HEINRICH PC
Citation: O. Weiergraber et al., SOLUBLE HUMAN INTERLEUKIN-6 RECEPTOR - EXPRESSION IN INSECT CELLS, PURIFICATION AND CHARACTERIZATION, European journal of biochemistry, 234(2), 1995, pp. 661-669
IDENTIFICATION OF 2 NOVEL REGIONS OF HUMAN IL-6 RESPONSIBLE FOR RECEPTOR-BINDING AND SIGNAL-TRANSDUCTION
Authors: EHLERS M GROTZINGER J DEHON FD MULLBERG J BRAKENHOFF JPJ LIU JW WOLLMER A ROSEJOHN S
Citation: M. Ehlers et al., IDENTIFICATION OF 2 NOVEL REGIONS OF HUMAN IL-6 RESPONSIBLE FOR RECEPTOR-BINDING AND SIGNAL-TRANSDUCTION, The Journal of immunology, 153(4), 1994, pp. 1744-1753
DEVELOPMENT OF AN INTERLEUKIN (IL)-6 RECEPTOR ANTAGONIST THAT INHIBITS IL-6-DEPENDENT GROWTH OF HUMAN MYELOMA CELLS
Authors: DEHON FD EHLERS M ROSEJOHN S EBELING SB BOS HK AARDEN LA BRAKENHOFF JPJ
Citation: Fd. Dehon et al., DEVELOPMENT OF AN INTERLEUKIN (IL)-6 RECEPTOR ANTAGONIST THAT INHIBITS IL-6-DEPENDENT GROWTH OF HUMAN MYELOMA CELLS, The Journal of experimental medicine, 180(6), 1994, pp. 2395-2400
DEVELOPMENT OF A HUMAN INTERLEUKIN-6 RECEPTOR ANTAGONIST
Authors: BRAKENHOFF JPJ DEHON FD FONTAINE V TENBOEKEL E SCHOOLTINK H ROSEJOHN S HEINRICH PC CONTENT J AARDEN LA
Citation: Jpj. Brakenhoff et al., DEVELOPMENT OF A HUMAN INTERLEUKIN-6 RECEPTOR ANTAGONIST, The Journal of biological chemistry, 269(1), 1994, pp. 86-93
PRODUCTION AND CHARACTERIZATION OF MONOCLONAL-ANTIBODIES RAISED AGAINST RECOMBINANT HUMAN GRANZYME-A AND GRANZYME-B AND SHOWING CROSS-REACTIONS WITH THE NATURAL PROTEINS
Authors: KUMMER JA KAMP AM VANKATWIJK M BRAKENHOFF JPJ RADOSEVIC K VANLEEUWEN AM BORST J VERWEIJ CL HACK CE
Citation: Ja. Kummer et al., PRODUCTION AND CHARACTERIZATION OF MONOCLONAL-ANTIBODIES RAISED AGAINST RECOMBINANT HUMAN GRANZYME-A AND GRANZYME-B AND SHOWING CROSS-REACTIONS WITH THE NATURAL PROTEINS, Journal of immunological methods, 163(1), 1993, pp. 77-83
STRUCTURE-FUNCTION ANALYSIS OF INTERLEUKIN-6 UTILIZING HUMAN MURINE CHIMERIC MOLECULES - INVOLVEMENT OF 2 SEPARATE DOMAINS IN RECEPTOR-BINDING
Authors: VANDAM M MULLBERG J SCHOOLTINK H STOYAN T BRAKENHOFF JPJ GRAEVE L HEINRICH PC ROSEJOHN S
Citation: M. Vandam et al., STRUCTURE-FUNCTION ANALYSIS OF INTERLEUKIN-6 UTILIZING HUMAN MURINE CHIMERIC MOLECULES - INVOLVEMENT OF 2 SEPARATE DOMAINS IN RECEPTOR-BINDING, The Journal of biological chemistry, 268(20), 1993, pp. 5285-5290
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