Authors:
HANCOCK AA
BUCKNER SA
BRUNE ME
KATWALA S
MILICIC I
IRELAND LM
MORSE PA
KNEPPER SM
MEYER MD
CHAPPLE CR
CHESSWILLIAMS R
NOBLE AJ
WILLIAMS M
KERWIN JF
Citation: Aa. Hancock et al., PHARMACOLOGICAL CHARACTERIZATION OF A-131701, A NOVEL ALPHA(1)-ADRENOCEPTOR ANTAGONIST SELECTIVE FOR ALPHA(1A)-COMPARED AND ALPHA(1D)-COMPARED TO ALPHA(1B)-ADRENOCEPTORS, Drug development research, 44(4), 1998, pp. 140-162
Authors:
LEE JY
HANCOCK AA
WARNER RB
BRUNE ME
MEYER MD
DEBERNARDIS JF
Citation: Jy. Lee et al., CARDIOVASCULAR ACTIVITY OF A-74283, A 5-HYDROXYTRYPTAMINE(1A) AGENT, IN THE SPONTANEOUSLY HYPERTENSIVE RAT, Pharmacology, 56(1), 1998, pp. 17-29
Authors:
HANCOCK AA
BRUNE ME
WITTE DG
MARSH KC
KATWALA S
MILICIC I
IRELAND LM
CROWELL D
MEYER MD
KERWIN JF
Citation: Aa. Hancock et al., ACTIONS OF A-131701, A NOVEL, SELECTIVE ANTAGONIST FOR ALPHA-1A COMPARED WITH ALPHA-1B ADRENOCEPTORS ON INTRAURETHRAL AND BLOOD-PRESSURE RESPONSES IN CONSCIOUS DOGS AND A PHARMACODYNAMIC ASSESSMENT OF IN-VIVO PROSTATIC SELECTIVITY, The Journal of pharmacology and experimental therapeutics, 285(2), 1998, pp. 628-642
Authors:
WITTE DG
BRUNE ME
KATWALA SP
MILICIC I
KERWIN JF
HANCOCK AA
Citation: Dg. Witte et al., RELATIONSHIPS BETWEEN PHARMACOKINETICS AND BLOCKADE OF AGONIST-INDUCED PROSTATIC INTRAURETHRAL PRESSURE AND MEAN ARTERIAL-PRESSURE IN THE CONSCIOUS DOG AFTER SINGLE AND REPEATED DAILY ORAL-ADMINISTRATION OF TERAZOSIN, The Journal of pharmacology and experimental therapeutics, 282(2), 1997, pp. 891-898
Authors:
MEYER MD
ALTENBACH RJ
BASHA FZ
CARROLL WA
DRIZIN I
ELMORE SW
EHRLICH PP
LEBOLD SA
TIETJE K
SIPPY KB
WENDT MD
PLATA DJ
PLAGGE F
BUCKNER SA
BRUNE ME
HANCOCK AA
KERWIN JF
Citation: Md. Meyer et al., SYNTHESIS AND PHARMACOLOGICAL CHARACTERIZATION OF AHYDRO-1H-BENZ[E]ISOINDOL-2-YL)ETHYL]PYRIDO-[3',4' 4,5]THIENO[3,2-D]PYRIMIDINE-2,4(1H,3H)-DIONE (A-131701) - A UROSELECTIVE ALPHA(1A) ADRENOCEPTOR ANTAGONIST FOR THE SYMPTOMATIC TREATMENT OF BENIGN PROSTATIC HYPERPLASIA/, Journal of medicinal chemistry, 40(20), 1997, pp. 3141-3143
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MILICIC IP
WITTE DG
KATWALA SP
HANCOCK AA
KERWIN JF
BRUNE ME
Citation: Ip. Milicic et al., RELATIONSHIP BETWEEN PLASMA-LEVELS AND BLOCKADE OF PHENYLEPHRINE-INDUCED INCREASES IN PROSTATIC INTRAURETHRAL PRESSURE AND MEAN ARTERIAL-PRESSURE FOLLOWING ACUTE AND SUBCHRONIC TERAZOSIN DOSING IN CONSCIOUS DOGS, The FASEB journal, 10(3), 1996, pp. 1002-1002
Authors:
KATWALA SP
MILICIC IP
HANCOCK AA
KERWIN JF
BRUNE ME
Citation: Sp. Katwala et al., DIFFERENTIAL-EFFECTS OF VARIOUS ALPHA-1-ADRENOCEPTOR ANTAGONISTS ON UROGENITAL AND VASCULAR SMOOTH-MUSCLE IN-VIVO, The FASEB journal, 10(3), 1996, pp. 2455-2455
Authors:
BRUNE ME
KATWALA SP
MILICIC I
BUCKNER SA
IRELAND LM
KERWIN JF
HANCOCK AA
Citation: Me. Brune et al., EFFECTS OF SELECTIVE AND NONSELECTIVE ALPHA-1-ADRENOCEPTOR ANTAGONISTS ON INTRAURETHRAL AND ARTERIAL PRESSURES IN INTACT CONSCIOUS DOGS, Pharmacology, 53(6), 1996, pp. 356-368
Authors:
GIBBONS JA
HANCOCK AA
VITT CR
KNEPPER S
BUCKNER SA
BRUNE ME
MILICIC I
KERWIN JF
RICHTER LS
TAYLOR EW
SPEAR KL
ZUCKERMANN RN
SPELLMEYER DC
BRAECKMAN RA
MOOS WH
Citation: Ja. Gibbons et al., PHARMACOLOGICAL CHARACTERIZATION OF CHIR-2279, AN N-SUBSTITUTED GLYCINE PEPTOID WITH HIGH-AFFINITY BINDING FOR ALPHA(1)-ADRENOCEPTORS, The Journal of pharmacology and experimental therapeutics, 277(2), 1996, pp. 885-899
Authors:
HANCOCK AA
BUCKNER SA
OHEIM KW
MORSE PA
BRUNE ME
MEYER MD
WILLIAMS M
KERWIN JF
Citation: Aa. Hancock et al., A-80426, A POTENT ALPHA(2)-ADRENOCEPTOR ANTAGONIST WITH SEROTONIN UPTAKE BLOCKING ACTIVITY AND PUTATIVE ANTIDEPRESSANT-LIKE EFFECTS .1. BIOCHEMICAL PROFILE, Drug development research, 35(4), 1995, pp. 237-245
Authors:
GIARDINA WJ
BUCKNER SA
BRUNE ME
HANCOCK AA
WISMER CT
MILICIC I
RATTIN AJ
ROUX S
WETTSTEIN JG
MEYER MD
PORSOLT RD
KERWIN JF
WILLIAMS M
Citation: Wj. Giardina et al., A-80426, A POTENT AND SELECTIVE ALPHA(2)-ADRENOCEPTOR ANTAGONIST WITHSEROTONIN UPTAKE-BLOCKING ACTIVITY AND PUTATIVE ANTIDEPRESSANT-LIKE EFFECTS .2. PHARMACOLOGY PROFILE, Drug development research, 35(4), 1995, pp. 246-260
Authors:
BRUNE ME
BUCKNER SA
POLAKOWSKI J
KERWIN JF
HANCOCK AA
Citation: Me. Brune et al., PHARMACOLOGICAL ANTAGONISM OF ALPHA-ADRENERGIC AGONIST-INDUCED INCREASES IN CANINE INTRAURETHRAL PRESSURE IN-VIVO, Drug development research, 34(3), 1995, pp. 267-275
Authors:
KNEPPER SM
BUCKNER SA
BRUNE ME
DEBERNARDIS JF
MEYER MD
HANCOCK AA
Citation: Sm. Knepper et al., A-61603, A POTENT ALPHA-1-ADRENERGIC RECEPTOR AGONIST, SELECTIVE FOR THE ALPHA-1A RECEPTOR SUBTYPE, The Journal of pharmacology and experimental therapeutics, 274(1), 1995, pp. 97-103
Authors:
HANCOCK AA
BUCKNER SA
GIARDINA WJ
BRUNE ME
LEE JY
MORSE PA
OHEIM KW
STANISIC DS
WARNER RB
KERKMAN DJ
DEBERNARDIS JF
Citation: Aa. Hancock et al., PRECLINICAL PHARMACOLOGICAL ACTIONS OF (+ YDRO-5',6'-METHYLENE-DIOXY-1'-NAPHTHALENYL)METHYL] PYRROLIDINE METHANESULFONATE (ABT-200), A POTENTIAL ANTIDEPRESSANT AGENT THAT ANTAGONIZES ALPHA-2-ADRENERGIC RECEPTORS AND INHIBITS THE NEURONAL UPTAKE OF NOREPINEPHRINE/, The Journal of pharmacology and experimental therapeutics, 272(3), 1995, pp. 1160-1169
Authors:
LEE JY
WARNER RB
BRUNE ME
ADLER AL
WINN M
DE B
ZYDOWSKY TM
OPGENORTH TJ
KERKMAN DJ
DEBENARDIS JF
Citation: Jy. Lee et al., CARDIOVASCULAR EFFECTS OF ORALLY-ADMINISTERED ABBOTT-81988, AN ANGIOTENSIN-II ANTAGONIST, IN CONSCIOUS SPONTANEOUSLY HYPERTENSIVE RATS, American journal of hypertension, 7(11), 1994, pp. 975-983
Authors:
LEE JY
BUCKNER SA
BRUNE ME
WARNER RB
WINN M
DE B
ZYDOWSKY TM
OPGENORTH TJ
KERKMAN DJ
DEBERNARDIS JF
Citation: Jy. Lee et al., CHARACTERIZATION OF ANTIHYPERTENSIVE ACTIVITY OF ABBOTT-81988, A NONPEPTIDE ANGIOTENSIN-II ANTAGONIST IN THE RENAL HYPERTENSIVE RAT, The Journal of pharmacology and experimental therapeutics, 268(1), 1994, pp. 427-433
Authors:
LEE JY
BRUNE ME
WARNER RB
BUCKNER SB
WINN M
DE B
ZYDOWSKY TM
OPGENORTH TJ
KERKMAN DJ
DEBERNARDIS JF
Citation: Jy. Lee et al., ANTIHYPERTENSIVE ACTIVITY OF ABBOTT-81282, A NONPEPTIDE ANGIOTENSIN-II ANTAGONIST, IN THE RENAL HYPERTENSIVE RAT, Pharmacology, 47(3), 1993, pp. 176-187
Authors:
WINN M
DE B
ZYDOWSKY TM
ALTENBACH RJ
BASHA FZ
BOYD SA
BRUNE ME
BUCKNER SA
CROWELL D
DRIZIN I
HANCOCK AA
JAE HS
KESTER JA
LEE JY
MANTEI RA
MARSH KC
NOVOSAD EI
OHEIM KW
ROSENBERG SH
SHIOSAKI K
SORENSEN BK
SPINA K
SULLIVAN GM
TASKER AS
VONGELDERN TW
WARNER RB
OPGENORTH TJ
KERKMAN DJ
DEBERNARDIS JF
Citation: M. Winn et al., 2-(ALKYLAMINO)NICOTINIC ACID AND ANALOGS - POTENT ANGIOTENSIN-II ANTAGONISTS, Journal of medicinal chemistry, 36(18), 1993, pp. 2676-2688