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Results: 1-17 |
Results: 17
Effect of a complex environmental mixture from coal tar containing polycyclic aromatic hydrocarbons (PAH) on the tumor initiation, PAH-DNA binding and metabolic activation of carcinogenic PAH in mouse epidermis
Authors: Marston, CP Pereira, C Ferguson, J Fischer, K Hedstrom, O Dashwood, WM Baird, WM
Citation: Cp. Marston et al., Effect of a complex environmental mixture from coal tar containing polycyclic aromatic hydrocarbons (PAH) on the tumor initiation, PAH-DNA binding and metabolic activation of carcinogenic PAH in mouse epidermis, CARCINOGENE, 22(7), 2001, pp. 1077-1086
Effects of the (-)-anti-11R,12S-dihydrodiol 13S,14R-epoxide of dibenzo[a,l]pyrene on DNA adduct formation and cell cycle arrest in human diploid fibroblasts
Authors: Mahadevan, B Luch, A Seidel, A Pelling, JC Baird, WM
Citation: B. Mahadevan et al., Effects of the (-)-anti-11R,12S-dihydrodiol 13S,14R-epoxide of dibenzo[a,l]pyrene on DNA adduct formation and cell cycle arrest in human diploid fibroblasts, CARCINOGENE, 22(1), 2001, pp. 161-169
Metabolic activation of dibenzo[a,l]pyrene by cytochrome P450 enzymes to stable DNA adducts occurs exclusively through the formation of the (-)-trans-(11R,12R)-diol
Authors: Luch, A Schober, W Greim, H Doehmer, J Jacob, J Seidel, A Baird, WM
Citation: A. Luch et al., Metabolic activation of dibenzo[a,l]pyrene by cytochrome P450 enzymes to stable DNA adducts occurs exclusively through the formation of the (-)-trans-(11R,12R)-diol, POLYCYCL AR, 21(1-4), 2000, pp. 87-98
Formation of stable DNA adducts and apurinic sites upon metabolic activation of bay and fjord region polycyclic aromatic hydrocarbons in human cell cultures
Authors: Melendez-Colon, VJ Luch, A Seidel, A Baird, WM
Citation: Vj. Melendez-colon et al., Formation of stable DNA adducts and apurinic sites upon metabolic activation of bay and fjord region polycyclic aromatic hydrocarbons in human cell cultures, CHEM RES T, 13(1), 2000, pp. 10-17
Cytochrome P4501B1 mediates induction of bone marrow cytotoxicity and preleukemia cells in mice treated with 7,12-dimethylbenz[a]anthracene
Authors: Heidel, SM MacWilliams, PS Baird, WM Dashwood, WM Buters, JTM Gonzalez, FJ Larsen, MC Czuprynski, CJ Jefcoate, CR
Citation: Sm. Heidel et al., Cytochrome P4501B1 mediates induction of bone marrow cytotoxicity and preleukemia cells in mice treated with 7,12-dimethylbenz[a]anthracene, CANCER RES, 60(13), 2000, pp. 3454-3460
Methyl group-induced helicity in 1,4-dimethylbenzo[c]phenanthrene and its metabolites: Synthesis, physical, and biological properties
Authors: Lakshman, MK Kole, PL Chaturvedi, S Saugier, JH Yeh, HJC Glusker, JP Carrell, HL Katz, AK Afshar, CE Dashwood, WM Kenniston, G Baird, WM
Citation: Mk. Lakshman et al., Methyl group-induced helicity in 1,4-dimethylbenzo[c]phenanthrene and its metabolites: Synthesis, physical, and biological properties, J AM CHEM S, 122(51), 2000, pp. 12629-12636
DNA modification induced after metabolic activation of the potent carcinogen dibenzo[a,l]pyrene in V79 Chinese hamster cells stably expressing singlecytochromes P450
Authors: Luch, A Coffing, SL Seidel, A Greim, H Baird, WM Doehmer, J
Citation: A. Luch et al., DNA modification induced after metabolic activation of the potent carcinogen dibenzo[a,l]pyrene in V79 Chinese hamster cells stably expressing singlecytochromes P450, POLYCYCL AR, 16(1-4), 1999, pp. 71-78
Role of cytochrome P450 1A1 and 1B1 in metabolic activation of dibenzo[a,l]pyrene by microsomes from the human mammary carcinoma cell line MCF-7
Authors: Cai, YN Marcus, C Guengerich, FP Gelboin, HV Baird, WM
Citation: Yn. Cai et al., Role of cytochrome P450 1A1 and 1B1 in metabolic activation of dibenzo[a,l]pyrene by microsomes from the human mammary carcinoma cell line MCF-7, POLYCYCL AR, 16(1-4), 1999, pp. 109-118
Relationship of dibenzo[a,l]pyrene-DNA binding to the induction of p53, p21(WAF1) and cell cycle arrest in human cells in culture
Authors: Baird, WM Kaspin, LC Kudla, K Seidel, A Greim, H Luch, A
Citation: Wm. Baird et al., Relationship of dibenzo[a,l]pyrene-DNA binding to the induction of p53, p21(WAF1) and cell cycle arrest in human cells in culture, POLYCYCL AR, 16(1-4), 1999, pp. 119-129
DNA repair of benzo[a]pyrene diol epoxide-DNA adducts in the DHFR gene of a human embryonic kidney cell line.
Authors: Schild, LJ Smith, CA Hanawalt, PC Baird, WM
Citation: Lj. Schild et al., DNA repair of benzo[a]pyrene diol epoxide-DNA adducts in the DHFR gene of a human embryonic kidney cell line., POLYCYCL AR, 16(1-4), 1999, pp. 131-139
Metabolic activation of 4H-cyclopenta[def]chrysene in human mammary carcinoma MCF-7 cell cultures
Authors: Agarwal, R Coffing, SL Baird, WM Harvey, RG Dipple, A
Citation: R. Agarwal et al., Metabolic activation of 4H-cyclopenta[def]chrysene in human mammary carcinoma MCF-7 cell cultures, CHEM RES T, 12(5), 1999, pp. 437-441
Molecular studies on the toxifying effects by genetically engineered cytochromes P450
Authors: Doehmer, J Buters, JTM Luch, A Soballa, V Baird, WM Morisson, H Stegeman, JJ Townsend, AJ Greenlee, WF Glatt, HR Seidel, A Jacob, J Greim, H
Citation: J. Doehmer et al., Molecular studies on the toxifying effects by genetically engineered cytochromes P450, DRUG METAB, 31(2), 1999, pp. 423-435
The level of DNA modification by (+)-syn-(11S,12R,13S,14R)- and (-)-anti-(11R,12S,13S,14R)-dihydrodiol epoxides of dibenzo[a,l]pyrene determined the effect on the proteins p53 and p21(WAF1) in the human mammary carcinoma cell line MCF-7
Authors: Luch, A Kudla, K Seidel, A Doehmer, J Greim, H Baird, WM
Citation: A. Luch et al., The level of DNA modification by (+)-syn-(11S,12R,13S,14R)- and (-)-anti-(11R,12S,13S,14R)-dihydrodiol epoxides of dibenzo[a,l]pyrene determined the effect on the proteins p53 and p21(WAF1) in the human mammary carcinoma cell line MCF-7, CARCINOGENE, 20(5), 1999, pp. 859-865
Cancer initiation by polycyclic aromatic hydrocarbons results from formation of stable DNA adducts rather than apurinic sites
Authors: Melendez-Colon, VJ Luch, A Seidel, A Baird, WM
Citation: Vj. Melendez-colon et al., Cancer initiation by polycyclic aromatic hydrocarbons results from formation of stable DNA adducts rather than apurinic sites, CARCINOGENE, 20(10), 1999, pp. 1885-1891
Inhibition of dibenzo[a,l] pyrene-induced multi-organ carcinogenesis by dietary chlorophyllin in rainbow trout
Authors: Reddy, AP Harttig, U Barth, MC Baird, WM Schimerlik, M Hendricks, JD Bailey, GS
Citation: Ap. Reddy et al., Inhibition of dibenzo[a,l] pyrene-induced multi-organ carcinogenesis by dietary chlorophyllin in rainbow trout, CARCINOGENE, 20(10), 1999, pp. 1919-1926
Comparison of cytochrome P450- and peroxidase-dependent metabolic activation of the potent carcinogen dibenzo[a,l]pyrene in human cell lines: Formation of stable DNA adducts and absence of a detectable increase in apurinic sites
Authors: Melendez-Colon, VJ Luch, A Seidel, A Baird, WM
Citation: Vj. Melendez-colon et al., Comparison of cytochrome P450- and peroxidase-dependent metabolic activation of the potent carcinogen dibenzo[a,l]pyrene in human cell lines: Formation of stable DNA adducts and absence of a detectable increase in apurinic sites, CANCER RES, 59(7), 1999, pp. 1412-1416
The K-region trans-8,9-diol does not significantly contribute as an intermediate in the metabolic activation of dibenzo[a,l]pyrene to DNA-binding metabolites by human cytochrome P450 1A1 or 1B1
Authors: Luch, A Kishiyama, S Seidel, A Doehmer, J Greim, H Baird, WM
Citation: A. Luch et al., The K-region trans-8,9-diol does not significantly contribute as an intermediate in the metabolic activation of dibenzo[a,l]pyrene to DNA-binding metabolites by human cytochrome P450 1A1 or 1B1, CANCER RES, 59(18), 1999, pp. 4603-4609
Risultati: 1-17 |