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Results: 1-14 |
Results: 14
Targeting of human Tmolt(4) leukemic type IIIMP dehydrogenase by cyclic imide related derivatives
Authors: Hall, IH Barnes, BJ Ward, ES Wheaton, JR Shaffer, KA Cho, SE Warren, AE
Citation: Ih. Hall et al., Targeting of human Tmolt(4) leukemic type IIIMP dehydrogenase by cyclic imide related derivatives, ARCH PHARM, 334(7), 2001, pp. 229-234
Tmolt(4) leukemic type II isoform of IMP dehydrogenase as a target for 1,2,4-triazolidine-3,5-diones, 1-(1-(3-methylphenyl)ethylidineamino)-4,4-diethyl-3,5-azetidinediones, 3,5-isoxazolidinediones, and 4,4-disubstituted-3,5-pyrazolidinediones
Authors: Hall, IH Barnes, BJ Ward, ES Wheaton, JR Warren, AE Izydore, RA
Citation: Ih. Hall et al., Tmolt(4) leukemic type II isoform of IMP dehydrogenase as a target for 1,2,4-triazolidine-3,5-diones, 1-(1-(3-methylphenyl)ethylidineamino)-4,4-diethyl-3,5-azetidinediones, 3,5-isoxazolidinediones, and 4,4-disubstituted-3,5-pyrazolidinediones, ARCH PHARM, 334(4), 2001, pp. 109-116
Analysis of the in vitro inhibition of murine and human tumor cell growth by pyrazole derivatives and a substituted azabicyclo[3.1.0] hexane-2,4-dione
Authors: Barnes, BJ Izydore, RA Hall, IH
Citation: Bj. Barnes et al., Analysis of the in vitro inhibition of murine and human tumor cell growth by pyrazole derivatives and a substituted azabicyclo[3.1.0] hexane-2,4-dione, ANTICANC R, 21(4A), 2001, pp. 2313-2321
Cytotoxicity and mode of action of 1-(1-cyclohexenyl) and 1-unsubstituted 3,5-pyrazolidinediones in human molt(4) T cell leukemia
Authors: Barnes, BJ Izydore, RA Hall, IH
Citation: Bj. Barnes et al., Cytotoxicity and mode of action of 1-(1-cyclohexenyl) and 1-unsubstituted 3,5-pyrazolidinediones in human molt(4) T cell leukemia, ANTICANC R, 21(3B), 2001, pp. 1857-1868
Cytotoxicity of 2-aldo- and 2-ketopyridine-N(4)-substituted thiosemicarbazones and mode of action in human Tmolt(4) cells
Authors: Hall, IH Barnes, BJ Rowell, JE Shaffer, KA Cho, SE West, DX Stark, AM
Citation: Ih. Hall et al., Cytotoxicity of 2-aldo- and 2-ketopyridine-N(4)-substituted thiosemicarbazones and mode of action in human Tmolt(4) cells, PHARMAZIE, 56(8), 2001, pp. 648-653
Specific inhibition of Type II inosine monophosphate dehydrogenase activity of Tmolt(4) T cell human leukaemia cells by 3-methoxy and di-benzohydroxamic acids, maleic hydrazide and malonic acids
Authors: Hall, IH Barnes, BJ Ward, ES Wheaton, JR Izydore, RA
Citation: Ih. Hall et al., Specific inhibition of Type II inosine monophosphate dehydrogenase activity of Tmolt(4) T cell human leukaemia cells by 3-methoxy and di-benzohydroxamic acids, maleic hydrazide and malonic acids, J PHARM PHA, 53(5), 2001, pp. 749-755
Induction of Tmolt(4) leukemia cell death by 3,3-disubstituted-6,6-pentamethylene-1,5-diazabicyclo[3.1.0]hexane-2,4-diones: Specificity for type II inosine 5 '-monophosphate dehydrogenase
Authors: Barnes, BJ Izydore, RA Eakin, AE Hall, IH
Citation: Bj. Barnes et al., Induction of Tmolt(4) leukemia cell death by 3,3-disubstituted-6,6-pentamethylene-1,5-diazabicyclo[3.1.0]hexane-2,4-diones: Specificity for type II inosine 5 '-monophosphate dehydrogenase, J PHARM EXP, 298(2), 2001, pp. 790-796
Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes
Authors: Barnes, BJ Moore, PA Pitha, PM
Citation: Bj. Barnes et al., Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes, J BIOL CHEM, 276(26), 2001, pp. 23382-23390
Mechanism of action of the antitumor agents 6-benzoyl-3,3-disubstituted-1,5-diazabicyclo[3.1.0]hexane-2,4-diones: Potent inhibitors of human type II inosine 5 '-monophosphate dehydrogenase
Authors: Barnes, BJ Izydore, RA Eakin, AE Hall, IH
Citation: Bj. Barnes et al., Mechanism of action of the antitumor agents 6-benzoyl-3,3-disubstituted-1,5-diazabicyclo[3.1.0]hexane-2,4-diones: Potent inhibitors of human type II inosine 5 '-monophosphate dehydrogenase, INT J CANC, 94(2), 2001, pp. 275-281
Implications of selective type IIIMP dehydrogenase (IMPDH) inhibition by the 6-ethoxycarbonyl-3,3-disubstituted-1,5-diazabicyclo[3.1.0]hexane-2,4-diones on tumor cell death
Authors: Barnes, BJ Eakin, AE Izydore, RA Hall, IH
Citation: Bj. Barnes et al., Implications of selective type IIIMP dehydrogenase (IMPDH) inhibition by the 6-ethoxycarbonyl-3,3-disubstituted-1,5-diazabicyclo[3.1.0]hexane-2,4-diones on tumor cell death, BIOCH PHARM, 62(1), 2001, pp. 91-100
The cytotoxicity of trifluoromethyl boron derivatives and mode of action in human Tmolt(3) T leukemic cells
Authors: Hall, IH Henry, JR Peaty, NJ Barnes, BJ Pawelke, G
Citation: Ih. Hall et al., The cytotoxicity of trifluoromethyl boron derivatives and mode of action in human Tmolt(3) T leukemic cells, APPL ORGAN, 14(2), 2000, pp. 86-97
Cytotoxicity of tantalum(V) and niobium(V) small carborane complexes and mode of action in P388 lymphocytic leukemia cells
Authors: Hall, IH Tolmie, CE Barnes, BJ Curtis, MA Russell, JM Finn, MG Grimes, RN
Citation: Ih. Hall et al., Cytotoxicity of tantalum(V) and niobium(V) small carborane complexes and mode of action in P388 lymphocytic leukemia cells, APPL ORGAN, 14(2), 2000, pp. 108-118
Cytotoxicity of rhenium(I) alkoxo and hydroxo carbonyl complexes in murineand human tumor cells
Authors: Yan, YK Cho, SE Shaffer, KA Rowell, JE Barnes, BJ Hall, IH
Citation: Yk. Yan et al., Cytotoxicity of rhenium(I) alkoxo and hydroxo carbonyl complexes in murineand human tumor cells, PHARMAZIE, 55(4), 2000, pp. 307-313
Selective inhibition of human molt-4 leukemia type II inosine 5 '-monophosphate dehydrogenase by the 1,5-diazabicyclo[3.1.0]hexane-2,4-diones
Authors: Barnes, BJ Eakin, AE Izydore, RA Hall, IH
Citation: Bj. Barnes et al., Selective inhibition of human molt-4 leukemia type II inosine 5 '-monophosphate dehydrogenase by the 1,5-diazabicyclo[3.1.0]hexane-2,4-diones, BIOCHEM, 39(45), 2000, pp. 13641-13650
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