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Authors: Huitema, ADR Mathot, RAA Tibben, MM Rodenhuis, S Beijnen, JH
Citation: Adr. Huitema et al., A mechanism-based pharmacokinetic model for the cytochrome P450 drug-drug interaction between cyclophosphamide and thioTEPA and the autoinduction of cyclophosphamide, J PHARMA PH, 28(3), 2001, pp. 211-230

Authors: Veldkamp, AI van Heeswijk, RPG Mulder, JW Meenhorst, PL Schreij, G van der Geest, S Lange, JMA Beijnen, JH Hoetelmans, RMW
Citation: Ai. Veldkamp et al., Steady-state pharmacokinetics of twice-daily dosing of saquinavir plus ritonavir in HIV-1-infected individuals, J ACQ IMM D, 27(4), 2001, pp. 344-349

Authors: Schoemaker, NE Frigerio, E Fraier, D Schellens, JHM Rosing, H Jansen, S Beijnen, JH
Citation: Ne. Schoemaker et al., High-performance liquid chromatographic analysis for the determination of a novel polymer-bound camptothecin derivative (MAG-camptothecin) and free camptothecin in human plasma, J CHROMAT B, 763(1-2), 2001, pp. 173-183

Authors: Bardelmeijer, HA Ouwehand, M Beijnen, JH Schellens, JHM van Tellingen, O
Citation: Ha. Bardelmeijer et al., Determination of cyclosporin A in human and mouse plasma by reversed-phasehigh-performance liquid chromatography, J CHROMAT B, 763(1-2), 2001, pp. 201-206

Authors: Kemper, EM Jansen, B Brouwer, KR Schellens, JHM Beijnen, JH van Tellingen, O
Citation: Em. Kemper et al., Bioanalysis and preliminary pharmacokinetics of the acridonecarboxamide derivative GF120918 in plasma of mice and humans by ion-pairing reversed-phase high-performance liquid chromatography with fluorescence detection, J CHROMAT B, 759(1), 2001, pp. 135-143

Authors: Huitema, ADR Reinders, C Tibben, MM Rodenhuis, S Beijnen, JH
Citation: Adr. Huitema et al., Sensitive gas chromatographic determination of the cyclophosphamide metabolite 2-dechloroethylcyclophosphamide in human plasma, J CHROMAT B, 757(2), 2001, pp. 349-357

Authors: Waterval, JCM Bloks, JC Sparidans, RW Beijnen, JH Rodriguez-Campos, IM Bult, A Lingeman, H Underberg, WJM
Citation: Jcm. Waterval et al., Degradation kinetics of aplidine, a new marine antitumoural cyclic peptide, in aqueous solution, J CHROMAT B, 754(1), 2001, pp. 161-168

Authors: Sparidans, RW Hoetelmans, RMW Beijnen, JH
Citation: Rw. Sparidans et al., Liquid chromatographic assay for simultaneous determination of abacavir and mycophenolic acid in human plasma using dual spectrophotometric detection, J CHROMAT B, 750(1), 2001, pp. 155-161

Authors: Malingre, MM Rosing, H Koopman, FJ Schellens, JHM Beijnen, JH
Citation: Mm. Malingre et al., Performance of the analytical assays of paclitaxel, docetaxel, and cyclosporin a in a routine hospital laboratory setting, J LIQ CHR R, 24(17), 2001, pp. 2697-2717

Authors: Maliepaard, M van Gastelen, MA Tohgo, A Hausheer, FH van Waardenburg, RCAM de Jong, LA Pluim, D Beijnen, JH Schellens, JHM
Citation: M. Maliepaard et al., Circumvention of breast cancer resistance protein (BCRP)-mediated resistance to camptothecins in vitro using non-substrate drugs or the BCRP inhibitor GF120918, CLIN CANC R, 7(4), 2001, pp. 935-941

Authors: Witkamp, AJ de Bree, E Kaag, MM Boot, H Beijnen, JH van Slooten, GW van Coevorden, F Zoetmulder, FAN
Citation: Aj. Witkamp et al., Extensive cytoreductive surgery followed by intra-operative hyperthermic intraperitoneal chemotherapy with mitomycin-C in patients with peritoneal carcinomatosis of colorectal origin, EUR J CANC, 37(8), 2001, pp. 979-984

Authors: Sparidans, RW Rosing, H Hillebrand, MJX Lopez-Lazaro, L Jimeno, JM Manzanares, I van Kesteren, C Cvitkovic, E van Oosterom, AT Schellens, JHM Beijnen, JH
Citation: Rw. Sparidans et al., Search for metabolites of ecteinascidin 743, a novel, marine-derived, anti-cancer agent, in man, ANTI-CANC D, 12(8), 2001, pp. 653-666

Authors: Sparidans, RW Stokvis, E Jimeno, JM Lopez-Lazaro, L Schellens, JHM Beijnen, JH
Citation: Rw. Sparidans et al., Chemical and enzymatic stability of a cyclic depsipeptide, the novel, marine-derived, anti-cancer agent kahalalide F, ANTI-CANC D, 12(7), 2001, pp. 575-582

Authors: Malingre, MM Huinink, WWT Duchin, K Schellens, JHM Beijnen, JH
Citation: Mm. Malingre et al., Pharmacokinetics of oral cyclosporin A when co-administered to enhance theoral absorption of paclitaxel, ANTI-CANC D, 12(7), 2001, pp. 591-593

Authors: van Maanen, MJ Huitema, ADR Rodenhuis, S Beijnen, JH
Citation: Mj. Van Maanen et al., Urinary excretion of thioTEPA and its metabolites in patients treated withhigh-dose cyclophosphamide, thioTEPA and carboplatin, ANTI-CANC D, 12(6), 2001, pp. 519-524

Authors: Terwogt, JMM Huinink, WWT Schellens, JHM Schot, M Mandjes, IAM Zurlo, MG Rocchetti, M Rosing, H Koopman, FJ Beijnen, JH
Citation: Jmm. Terwogt et al., Phase I clinical and pharmacokinetic study of PNU166945, a novel water-soluble polymer-conjugated prodrug of paclitaxel, ANTI-CANC D, 12(4), 2001, pp. 315-323

Authors: Malingre, MM Beijnen, JH Rosing, H Koopman, FJ van Tellingen, O Duchin, K Huinink, WWT Swart, M Lieverst, J Schellens, JHM
Citation: Mm. Malingre et al., The effect of different doses of cyclosporin A on the systemic exposure oforally administered paclitaxel, ANTI-CANC D, 12(4), 2001, pp. 351-358

Authors: Crul, M de Klerk, GJ Beijnen, JH Schellens, JHM
Citation: M. Crul et al., Ras biochemistry and farnesyl transferase inhibitors: a literature survey, ANTI-CANC D, 12(3), 2001, pp. 163-184

Authors: Crul, M van den Bongard, HJGD Tibben, MM van Tellingen, O Sava, G Schellens, JHM Beijnen, JH
Citation: M. Crul et al., Validated method for the determination of the novel organo-ruthenium anticancer drug NAMI-A in human biological fluids by Zeeman atomic absorption spectrometry, FRESEN J AN, 369(5), 2001, pp. 442-445

Authors: van Putten, JWG Kerbush, T Smit, EF van Rijswijk, R Beijnen, JH Sleijfer, DT Groen, HJM
Citation: Jwg. Van Putten et al., Dose-finding and pharmacological study of ifosfamide in combination with paclitaxel and carboplatin in resistant small-cell lung cancer, ANN ONCOL, 12(6), 2001, pp. 787-792

Authors: Malingre, MM Richel, DJ Beijnen, JH Rosing, H Koopman, FJ Huinink, WWTB Schot, ME Schellens, JHM
Citation: Mm. Malingre et al., Coadministration of cyclosporine strongly enhances the oral bioavailability of docetaxel, J CL ONCOL, 19(4), 2001, pp. 1160-1166

Authors: Nuijen, B Bouma, M Talsma, H Manada, C Jimeno, JM Lopez-Lazaro, L Bult, A Beijnen, JH
Citation: B. Nuijen et al., Development of a lyophilized parenteral pharmaceutical formulation of the investigational polypeptide marine anticancer agent kahalalide F, DRUG DEV IN, 27(8), 2001, pp. 767-780

Authors: Kerbusch, T vanPutten, JWG Groen, HJM Huitema, ADR Mathot, RAA Beijnen, JH
Citation: T. Kerbusch et al., Population pharmacokinetics of ifosfamide and its 2-and 3-dechloroethylated and 4-hydroxylated metabolites in resistant small-cell lung cancer patients, CANC CHEMOT, 48(1), 2001, pp. 53-61

Authors: van den Bongard, HJGD Mathot, RAA Boogerd, W Schornagel, JH Soesan, M Schellens, JHM Beijnen, JH
Citation: Hjgd. Van Den Bongard et al., Successful rescue with leucovorin and thymidine in a patient with high-dose methotrexate induced acute renal failure, CANC CHEMOT, 47(6), 2001, pp. 537-540

Authors: Malingre, MM Beijnen, JH Rosing, H Koopman, FJ van Tellingen, O Duchin, K Huinink, WWT Swart, M Lieverst, J Schellens, JHM
Citation: Mm. Malingre et al., A phase I and pharmacokinetic study of bi-daily dosing of oral paclitaxel in combination with cyclosporin A, CANC CHEMOT, 47(4), 2001, pp. 347-354
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