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Results: 1-18 |
Results: 18
Design and synthesis of a multivalent homing device for targeting to murine CD22
Authors: Sliedregt, LAJM van Rossenberg, SMW Autar, R Valentijn, ARPM van der Marel, GA van Boom, JH Piperi, C van der Merwe, PA Kuiper, J van Berkel, TJC Biessen, EAL
Citation: Lajm. Sliedregt et al., Design and synthesis of a multivalent homing device for targeting to murine CD22, BIO MED CH, 9(1), 2001, pp. 85-97
Attenuation of atherogenesis by systemic and local adenovirus-mediated gene transfer of interleukin-10 in LDLr - /- Mice
Authors: von der Thusen, JH Kuiper, J Fekkes, ML de Vos, P van Berkel, TJC Biessen, EAL
Citation: Jh. Von Der Thusen et al., Attenuation of atherogenesis by systemic and local adenovirus-mediated gene transfer of interleukin-10 in LDLr - /- Mice, FASEB J, 15(12), 2001, pp. NIL_19-NIL_37
Recombinant lipoproteins: lipoprotein-like lipid particles for drug targeting
Authors: Rensen, PCN de Vrueh, RLA Kuiper, J Bijsterbosch, MK Biessen, EAL van Berkel, TJC
Citation: Pcn. Rensen et al., Recombinant lipoproteins: lipoprotein-like lipid particles for drug targeting, ADV DRUG DE, 47(2-3), 2001, pp. 251-276
Carrier-mediated delivery improves the efficacy of 9-(2-phosphonylmethoxyethyl)adenine against hepatitis B virus
Authors: Bijsterbosch, MK Ying, CX De Vrueh, RLA De Clercq, E Biessen, EAL Neyts, J Van Berkel, TJC
Citation: Mk. Bijsterbosch et al., Carrier-mediated delivery improves the efficacy of 9-(2-phosphonylmethoxyethyl)adenine against hepatitis B virus, MOLEC PHARM, 60(3), 2001, pp. 521-527
Determination of the upper size limit for uptake and processing of ligandsby the asialoglycoprotein receptor on hepatocytes in vitro and in vivo
Authors: Rensen, PCN Sliedregt, LAJM Ferns, A Kieviet, E van Rossenberg, SMW van Leeuwen, SH van Berkel, TJC Biessen, EAL
Citation: Pcn. Rensen et al., Determination of the upper size limit for uptake and processing of ligandsby the asialoglycoprotein receptor on hepatocytes in vitro and in vivo, J BIOL CHEM, 276(40), 2001, pp. 37577-37584
A structure-function study of ligand recognition by CD22 beta
Authors: van Rossenberg, SMW Sliedregt, LAJM Autar, R Piperi, C Van der Merwe, AP van Berkel, TJC Kuiper, J Biessen, EAL
Citation: Smw. Van Rossenberg et al., A structure-function study of ligand recognition by CD22 beta, J BIOL CHEM, 276(16), 2001, pp. 12967-12973
Induction of rapid atherogenesis by perivascular carotid collar placement in apolipoprotein E-deficient and low-density lipoprotein receptor-deficient mice
Authors: von der Thusen, JH van Berkel, TJC Biessen, EAL
Citation: Jh. Von Der Thusen et al., Induction of rapid atherogenesis by perivascular carotid collar placement in apolipoprotein E-deficient and low-density lipoprotein receptor-deficient mice, CIRCULATION, 103(8), 2001, pp. 1164-1170
Delivery of cholesteryl-conjugated phosphorothioate oligodeoxynucleotides to Kupffer cells by lactosylated low-density lipoprotein
Authors: Bijsterbosch, MK Manoharan, M Dorland, R Waarlo, IHE Biessen, EAL van Berkel, TJC
Citation: Mk. Bijsterbosch et al., Delivery of cholesteryl-conjugated phosphorothioate oligodeoxynucleotides to Kupffer cells by lactosylated low-density lipoprotein, BIOCH PHARM, 62(5), 2001, pp. 627-633
Novel hepatotrophic prodrugs of the antiviral nucleoside 9-(2-phosphonylmethoxyethyl)adenine with improved pharmacokinetics and antiviral activity
Authors: Biessen, EAL Valentijn, ARPM De Vrueh, RLA Van de Bilt, E Sliedregt, LAJM Prince, P Bijsterbosch, MK Van Boom, JH Van der Marel, GA Abrahams, PJ Van Berkel, TJC
Citation: Eal. Biessen et al., Novel hepatotrophic prodrugs of the antiviral nucleoside 9-(2-phosphonylmethoxyethyl)adenine with improved pharmacokinetics and antiviral activity, FASEB J, 14(12), 2000, pp. 1784-1792
Modulation of plasma protein binding and in vivo liver cell uptake of phosphorothioate oligodeoxynucleotides by cholesterol conjugation
Authors: Bijsterbosch, MK Rump, ET De Vrueh, RLA Dorland, R van Veghel, R Tivel, KL Biessen, EAL van Berkel, TJC Manoharan, M
Citation: Mk. Bijsterbosch et al., Modulation of plasma protein binding and in vivo liver cell uptake of phosphorothioate oligodeoxynucleotides by cholesterol conjugation, NUCL ACID R, 28(14), 2000, pp. 2717-2725
Targeted delivery of antisense oligonucleotides to parenchymal liver cellsin vivo
Authors: Biessen, EAL Vietsch, H Rump, ET Fluiter, K Bijsterbosch, MK van Berkel, TJC
Citation: Eal. Biessen et al., Targeted delivery of antisense oligonucleotides to parenchymal liver cellsin vivo, METH ENZYM, 314, 2000, pp. 324-342
Carrier-mediated delivery of 9-(2-phosphonylmethoxyethyl)adenine to parenchymal liver cells: a novel therapeutic approach for hepatitis B
Authors: de Vrueh, RLA Rump, ET van de Bilt, E van Veghel, R Balzarini, J Biessen, EAL van Berkel, TJC Bijsterbosch, MK
Citation: Rla. De Vrueh et al., Carrier-mediated delivery of 9-(2-phosphonylmethoxyethyl)adenine to parenchymal liver cells: a novel therapeutic approach for hepatitis B, ANTIM AG CH, 44(3), 2000, pp. 477-483
Apolipoprotein E is resistant to intracellular degradation in vitro and invivo - Evidence for retroendocytosis
Authors: Rensen, PCN Jong, MC van Vark, LC van der Boom, H Hendriks, WL van Berkel, TJC Biessen, EAL Havekes, LM
Citation: Pcn. Rensen et al., Apolipoprotein E is resistant to intracellular degradation in vitro and invivo - Evidence for retroendocytosis, J BIOL CHEM, 275(12), 2000, pp. 8564-8571
alpha 3-Galactosylated glycoproteins can bind to the hepaticasialoglycoprotein receptor
Authors: Joziasse, DH Lee, RT Lee, YC Biessen, EAL Schiphorst, WECM Koeleman, CAM van den Eijnden, DH
Citation: Dh. Joziasse et al., alpha 3-Galactosylated glycoproteins can bind to the hepaticasialoglycoprotein receptor, EUR J BIOCH, 267(21), 2000, pp. 6501-6508
Modification of the plasma clearance and liver uptake of steroid ester-conjugated oligodeoxynucleotides by association with (lactosylated) low-density lipoprotein
Authors: Rump, ET de Vrueh, RLA Manoharan, M Waarlo, IHE van Veghel, R Biessen, EAL van Berkel, TJC Bijsterbosch, MK
Citation: Et. Rump et al., Modification of the plasma clearance and liver uptake of steroid ester-conjugated oligodeoxynucleotides by association with (lactosylated) low-density lipoprotein, BIOCH PHARM, 59(11), 2000, pp. 1407-1416
Synthesis of a lipophilic prodrug of 9-(2-phosphonylmethoxyethyl)adenine (PMEA) and its incorporation into a hepatocyte-specific lipidic carrier
Authors: de Vrueh, RLA Rump, ET Sliedregt, LAJM Biessen, EAL van Berkel, TJC Bijsterbosch, MK
Citation: Rla. De Vrueh et al., Synthesis of a lipophilic prodrug of 9-(2-phosphonylmethoxyethyl)adenine (PMEA) and its incorporation into a hepatocyte-specific lipidic carrier, PHARM RES, 16(8), 1999, pp. 1179-1185
Targeted delivery of oligodeoxynucleotides to parenchymal liver cells in vivo
Authors: Biessen, EAL Vietsch, H Rump, ET Fluiter, K Kuiper, J Bijsterbosch, MK Van Berkel, TJC
Citation: Eal. Biessen et al., Targeted delivery of oligodeoxynucleotides to parenchymal liver cells in vivo, BIOCHEM J, 340, 1999, pp. 783-792
Design and synthesis of novel amphiphilic dendritic galactosides for selective targeting of liposomes to the hepatic asialoglycoprotein receptor
Authors: Sliedregt, LAJM Rensen, PCN Rump, ET van Santbrink, PJ Bijsterbosch, MK Valentijn, ARPM van der Marel, GA van Boom, JH van Berkel, TJC Biessen, EAL
Citation: Lajm. Sliedregt et al., Design and synthesis of novel amphiphilic dendritic galactosides for selective targeting of liposomes to the hepatic asialoglycoprotein receptor, J MED CHEM, 42(4), 1999, pp. 609-618
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