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Results: 1-17 |
Results: 17
Synthesis of anticonvulsive AMPA antagonists: 4-oxo-10-substituted-imidazo[1,2-a]indeno[1,2-e]pyrazin-2-carboxylic acid derivatives
Authors: Stutzmann, JM Bohme, GA Boireau, A Damour, D Debono, MW Genevois-Borella, A Jimonet, P Pratt, J Randle, JCR Ribeill, Y Vuilhorgne, M Mignani, S
Citation: Jm. Stutzmann et al., Synthesis of anticonvulsive AMPA antagonists: 4-oxo-10-substituted-imidazo[1,2-a]indeno[1,2-e]pyrazin-2-carboxylic acid derivatives, BIOORG MED, 11(9), 2001, pp. 1205-1210
Bioisosteres of 9-carboxymethyl-4-oxo-imidazo[1,2-a]indeno-[1,2-e]pyrazin-2-carboxylic acid derivatives. Progress towards selective, potent in vivo AMPA antagonists with longer durations of action
Authors: Jimonet, P Bohme, GA Bouquerel, J Boireau, A Damour, D Debono, MW Genevois-Borella, A Hardy, JC Hubert, P Manfre, F Nemecek, P Pratt, J Randle, JCR Ribeill, Y Stutzmann, JM Vuilhorgne, M Mignani, S
Citation: P. Jimonet et al., Bioisosteres of 9-carboxymethyl-4-oxo-imidazo[1,2-a]indeno-[1,2-e]pyrazin-2-carboxylic acid derivatives. Progress towards selective, potent in vivo AMPA antagonists with longer durations of action, BIOORG MED, 11(2), 2001, pp. 127-132
RPR 119990, a novel alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid antagonist: Synthesis, pharmacological properties, and activity in an animal model of amyotrophic lateral sclerosis
Authors: Canton, T Bohme, GA Boireau, A Bordier, F Mignani, S Jimonet, P Jahn, G Alavijeh, M Stygall, J Roberts, S Brealey, C Vuilhorgne, M Debono, MW Le Guern, S Laville, M Briet, D Roux, M Stutzmann, JM Pratt, J
Citation: T. Canton et al., RPR 119990, a novel alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid antagonist: Synthesis, pharmacological properties, and activity in an animal model of amyotrophic lateral sclerosis, J PHARM EXP, 299(1), 2001, pp. 314-322
8-Methylureido-10-amino-10-methyl-imidazo[1,2-a]indeno[1,2-e] pyrazine-4-ones: Highly in vivo potent and selective AMPA receptor antagonists
Authors: Jimonet, P Cheve, M Bohme, GA Boireau, A Damour, D Debono, MW Genevois-Borella, A Imperato, A Pratt, J Randle, JCR Ribeill, Y Stutzmann, JM Vuilhorgne, M Mignani, S
Citation: P. Jimonet et al., 8-Methylureido-10-amino-10-methyl-imidazo[1,2-a]indeno[1,2-e] pyrazine-4-ones: Highly in vivo potent and selective AMPA receptor antagonists, BIO MED CH, 8(8), 2000, pp. 2211-2217
8-Methylureido-4,5-dihyro-4-oxo-10H-imidazo[1,2-a]indeno[1,2-e]pyrazines: Highly potent in vivo AMPA antagonists
Authors: Mignani, S Bohme, GA Boireau, A Cheve, M Damour, D Debono, MW Genevois-Borella, A Imperato, A Jimonet, P Pratt, J Randle, JCR Ribeill, Y Vuilhorgne, M Stutzmann, JM
Citation: S. Mignani et al., 8-Methylureido-4,5-dihyro-4-oxo-10H-imidazo[1,2-a]indeno[1,2-e]pyrazines: Highly potent in vivo AMPA antagonists, BIOORG MED, 10(6), 2000, pp. 591-596
Synthesis and potent anticonvulsant activities of 4-oxo-imidazo[1,2-a]indeno[1,2-e]pyrazin-8-and-9-carboxylic (acetic) acid AMPA antagonists
Authors: Pratt, J Jimonet, P Bohme, GA Boireau, A Damour, D Debono, MW Genevois-Borella, A Randle, JCR Ribeill, Y Stutzmann, JM Vuilhorgne, M Mignani, S
Citation: J. Pratt et al., Synthesis and potent anticonvulsant activities of 4-oxo-imidazo[1,2-a]indeno[1,2-e]pyrazin-8-and-9-carboxylic (acetic) acid AMPA antagonists, BIOORG MED, 10(24), 2000, pp. 2749-2754
4,10-dihydro-4-oxo-4H-imidazo[1,2-a]indeno[1,2-e]pyrazin-2-carboxylic acidderivatives: Highly potent and selective AMPA receptors antagonists with in vivo activity
Authors: Stutzmann, JM Bohme, GA Boireau, A Damour, D Debono, MW Genevois-Borella, A Imperato, A Jimonet, P Pratt, J Randle, JCR Ribeill, Y Vuilhorgne, M Mignani, S
Citation: Jm. Stutzmann et al., 4,10-dihydro-4-oxo-4H-imidazo[1,2-a]indeno[1,2-e]pyrazin-2-carboxylic acidderivatives: Highly potent and selective AMPA receptors antagonists with in vivo activity, BIOORG MED, 10(10), 2000, pp. 1133-1137
Adaptive changes in the nigrostriatal pathway in response to increased 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurodegeneration in the mouse
Authors: Bezard, E Jaber, M Gonon, F Boireau, A Bloch, B Gross, CE
Citation: E. Bezard et al., Adaptive changes in the nigrostriatal pathway in response to increased 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurodegeneration in the mouse, EUR J NEURO, 12(8), 2000, pp. 2892-2900
The anti-oxidant ebselen antagonizes the release of the apoptogenic factorcytochrome c induced by Fe2+/citrate in rat liver mitochondria
Authors: Boireau, A Marechal, PA Meunier, M Dubedat, P Moussaoui, S
Citation: A. Boireau et al., The anti-oxidant ebselen antagonizes the release of the apoptogenic factorcytochrome c induced by Fe2+/citrate in rat liver mitochondria, NEUROSCI L, 289(2), 2000, pp. 95-98
Biomarker stratigraphic records over the last 150 kyears off the NW African coast at 25 degrees N
Authors: Sicre, MA Ternois, Y Paterne, M Boireau, A Beaufort, L Martinez, P Bertrand, P
Citation: Ma. Sicre et al., Biomarker stratigraphic records over the last 150 kyears off the NW African coast at 25 degrees N, ORG GEOCHEM, 31(6), 2000, pp. 577-588
The protective effect of riluzole in the MPTP model of Parkinson's diseasein mice is not due to a decrease in MPP+ accumulation
Authors: Boireau, A Dubedat, P Bordier, F Imperato, A Moussaoui, S
Citation: A. Boireau et al., The protective effect of riluzole in the MPTP model of Parkinson's diseasein mice is not due to a decrease in MPP+ accumulation, NEUROPHARM, 39(6), 2000, pp. 1016-1020
Indeno[1,2-b]pyrazin-2,3-diones: A new class of antagonists at the glycinesite of the NMDA receptor with potent in vivo activity
Authors: Jimonet, P Ribeill, Y Bohme, GA Boireau, A Cheve, M Damour, D Doble, A Genevois-Borella, A Herman, F Imperato, A Le Guern, S Manfre, F Pratt, J Randle, JCR Stutzmann, JM Mignani, S
Citation: P. Jimonet et al., Indeno[1,2-b]pyrazin-2,3-diones: A new class of antagonists at the glycinesite of the NMDA receptor with potent in vivo activity, J MED CHEM, 43(12), 2000, pp. 2371-2381
Effects of RPR 118723, a novel antagonist at the glycine site of the NMDA receptor, in vitro
Authors: Boireau, A Monterrat, C Bordier, F Meunier, M Imperato, A
Citation: A. Boireau et al., Effects of RPR 118723, a novel antagonist at the glycine site of the NMDA receptor, in vitro, EUR J PHARM, 401(2), 2000, pp. 131-135
Spiro-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one derivatives are mixed AMPAand NMDA glycine-site antagonists active in vivo.
Authors: Jimonet, P Boireau, A Cheve, M Damour, D Genevois-Borella, A Imperato, A Pratt, J Randle, JCR Ribeill, Y Stutzmann, JM Mignani, S
Citation: P. Jimonet et al., Spiro-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one derivatives are mixed AMPAand NMDA glycine-site antagonists active in vivo., BIOORG MED, 9(20), 1999, pp. 2921-2926
Synthesis and pharmacological properties of 5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one, a new competitive AMPA/KA receptor antagonist
Authors: Mignani, S Aloup, JC Barreau, M Blanchard, JC Bohme, GA Boireau, A Damour, D Debono, MW Dubroeucq, MC Genevois-Borella, A Imperato, A Jimonet, P Pratt, J Randle, JCR Reibaud, M Ribeill, Y Stutzmann, JM
Citation: S. Mignani et al., Synthesis and pharmacological properties of 5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one, a new competitive AMPA/KA receptor antagonist, DRUG DEV R, 48(3), 1999, pp. 121-129
Riluzole Series. Synthesis and in vivo "antiglutamate" activity of 6-substituted-2-benzothiazolamines and 3-substituted-2-imino-benzothiazalines
Authors: Jimonet, P Audiau, F Barreau, M Blanchard, JC Boireau, A Bour, Y Coleno, MA Doble, A Doerflinger, G Hu, CD Donat, MH Duchesne, JM Ganil, P Gueremy, C Honore, E Just, B Kerphirique, R Gontier, S Hubert, P Laduron, PM Le Blevec, J Meunier, R Miquet, JM Nemecek, C Pasquet, M Piot, O Pratt, J Rataud, J Reibaud, N Stutzmann, JM Mignani, S
Citation: P. Jimonet et al., Riluzole Series. Synthesis and in vivo "antiglutamate" activity of 6-substituted-2-benzothiazolamines and 3-substituted-2-imino-benzothiazalines, J MED CHEM, 42(15), 1999, pp. 2828-2843
Ouabain-induced increase in dopamine release from mouse striatal slices isantagonized by riluzole
Authors: Boireau, A Meunier, M Imperato, A
Citation: A. Boireau et al., Ouabain-induced increase in dopamine release from mouse striatal slices isantagonized by riluzole, J PHARM PHA, 50(11), 1998, pp. 1293-1297
Risultati: 1-17 |