AAAAAA

   
Results: 1-20 |
Results: 20
Osmolytes as modulators of conformational changes in serpins
Authors: Chow, MKM Devlin, GL Bottomley, SP
Citation: Mkm. Chow et al., Osmolytes as modulators of conformational changes in serpins, BIOL CHEM, 382(11), 2001, pp. 1593-1599
Prevention of polymerization of M and Z alpha(1)-antitrypsin (alpha(1)-AT)with trimethylamine N-oxide - Implications for the treatment of alpha(1)-AT deficiency
Authors: Devlin, GL Parfrey, H Tew, DJ Lomas, DA Bottomley, SP
Citation: Gl. Devlin et al., Prevention of polymerization of M and Z alpha(1)-antitrypsin (alpha(1)-AT)with trimethylamine N-oxide - Implications for the treatment of alpha(1)-AT deficiency, AM J RESP C, 24(6), 2001, pp. 727-732
Complex between Peptostreptococcus magnus protein L and a human antibody reveals structural convergence in the interaction modes of Fab binding proteins
Authors: Graille, M Stura, EA Housden, NG Beckingham, JA Bottomley, SP Beale, D Taussig, MJ Sutton, BJ Gore, MG Charbonnier, JB
Citation: M. Graille et al., Complex between Peptostreptococcus magnus protein L and a human antibody reveals structural convergence in the interaction modes of Fab binding proteins, STRUCTURE, 9(8), 2001, pp. 679-687
The role of strand 1 of the C beta-sheet in the structure and function of alpha(1)-antitrypsin
Authors: Bottomley, SP Lawrenson, ID Tew, D Dai, WW Whisstock, JC Pike, RN
Citation: Sp. Bottomley et al., The role of strand 1 of the C beta-sheet in the structure and function of alpha(1)-antitrypsin, PROTEIN SCI, 10(12), 2001, pp. 2518-2524
Studies on a single immunoglobulin-binding domain of protein L from Peptostreptococcus magnus: the role of tyrosine-53 in the reaction with human IgG
Authors: Beckingham, JA Housden, NG Muir, NM Bottomley, SP Gore, MG
Citation: Ja. Beckingham et al., Studies on a single immunoglobulin-binding domain of protein L from Peptostreptococcus magnus: the role of tyrosine-53 in the reaction with human IgG, BIOCHEM J, 353, 2001, pp. 395-401
Probing the equilibrium denaturation of the serpin alpha(1)-antitrypsin with single tryptophan mutants; Evidence for structure in the urea unfolded state
Authors: Tew, DJ Bottomley, SP
Citation: Dj. Tew et Sp. Bottomley, Probing the equilibrium denaturation of the serpin alpha(1)-antitrypsin with single tryptophan mutants; Evidence for structure in the urea unfolded state, J MOL BIOL, 313(5), 2001, pp. 1161-1169
Intrinsic fluorescence changes and rapid kinetics of proteinase deformation during serpin inhibition
Authors: Tew, DJ Bottomley, SP
Citation: Dj. Tew et Sp. Bottomley, Intrinsic fluorescence changes and rapid kinetics of proteinase deformation during serpin inhibition, FEBS LETTER, 494(1-2), 2001, pp. 30-33
Structure of a serpin-enzyme complex probed by cysteine substitutions and fluorescence spectroscopy
Authors: Ludeman, JP Whisstock, JC Hopkins, PCR Le Bonniec, BF Bottomley, SP
Citation: Jp. Ludeman et al., Structure of a serpin-enzyme complex probed by cysteine substitutions and fluorescence spectroscopy, BIOPHYS J, 80(1), 2001, pp. 491-497
Cleaved antitrypsin polymers at atomic resolution
Authors: Dunstone, MA Dai, WW Whisstock, JC Rossjohn, J Pike, RN Feil, SC Le Bonniec, BF Parker, MW Bottomley, SP
Citation: Ma. Dunstone et al., Cleaved antitrypsin polymers at atomic resolution, PROTEIN SCI, 9(2), 2000, pp. 417-420
The citrate ion increases the conformational stability of alpha(1)-antitrypsin
Authors: Bottomley, SP Tew, DJ
Citation: Sp. Bottomley et Dj. Tew, The citrate ion increases the conformational stability of alpha(1)-antitrypsin, BBA-PROT ST, 1481(1), 2000, pp. 11-17
Protease-activated receptor-2 mediates proliferative responses in skeletalmyoblasts
Authors: Chinni, C de Niese, MR Jenkins, AL Pike, RN Bottomley, SP Mackie, EJ
Citation: C. Chinni et al., Protease-activated receptor-2 mediates proliferative responses in skeletalmyoblasts, J CELL SCI, 113(24), 2000, pp. 4427-4433
The inositol polyphosphate 5-phosphatases and the apurinic/apyrimidinic base excision repair endonucleases share a common mechanism for catalysis
Authors: Whisstock, JC Romero, S Gurung, R Nandurkar, H Ooms, LM Bottomley, SP Mitchell, CA
Citation: Jc. Whisstock et al., The inositol polyphosphate 5-phosphatases and the apurinic/apyrimidinic base excision repair endonucleases share a common mechanism for catalysis, J BIOL CHEM, 275(47), 2000, pp. 37055-37061
Conformational change and intermediates in the unfolding of alpha(1)-antichymotrypsin
Authors: Pearce, MC Rubin, H Bottomley, SP
Citation: Mc. Pearce et al., Conformational change and intermediates in the unfolding of alpha(1)-antichymotrypsin, J BIOL CHEM, 275(37), 2000, pp. 28513-28518
Serpins in the Caenorhabditis elegans genome
Authors: Whisstock, JC Irving, JA Bottomley, SP Pike, RN Lesk, AM
Citation: Jc. Whisstock et al., Serpins in the Caenorhabditis elegans genome, PROTEINS, 36(1), 1999, pp. 31-41
The production and characterisation of an immobilised chaperonin system
Authors: Preston, NS Baker, DJ Bottomley, SP Gore, MG
Citation: Ns. Preston et al., The production and characterisation of an immobilised chaperonin system, BBA-GEN SUB, 1426(1), 1999, pp. 99-109
Interactions between a single immunoglobulin-binding domain of protein L from Peptostreptococcus magnus and a human kappa light chain
Authors: Beckingham, JA Bottomley, SP Hinton, R Sutton, BJ Gore, MG
Citation: Ja. Beckingham et al., Interactions between a single immunoglobulin-binding domain of protein L from Peptostreptococcus magnus and a human kappa light chain, BIOCHEM J, 340, 1999, pp. 193-199
Thrombin, a survival factor for cultured myoblasts
Authors: Chinni, C de Niese, MR Tew, DJ Jenkins, AL Bottomley, SP Mackie, EJ
Citation: C. Chinni et al., Thrombin, a survival factor for cultured myoblasts, J BIOL CHEM, 274(14), 1999, pp. 9169-9174
Probing the unfolding pathway of alpha(1)-antitrypsin
Authors: James, EL Whisstock, JC Gore, MG Bottomley, SP
Citation: El. James et al., Probing the unfolding pathway of alpha(1)-antitrypsin, J BIOL CHEM, 274(14), 1999, pp. 9482-9488
The intracellular serpin proteinase inhibitor 6 is expressed in monocytes and granulocytes and is a potent inhibitor of the azurophilic granule protease, cathepsin G
Authors: Scott, FL Hirst, CE Sun, JR Bird, CH Bottomley, SP Bird, PI
Citation: Fl. Scott et al., The intracellular serpin proteinase inhibitor 6 is expressed in monocytes and granulocytes and is a potent inhibitor of the azurophilic granule protease, cathepsin G, BLOOD, 93(6), 1999, pp. 2089-2097
Protein engineering of chimeric Serpins: an investigation into effects of the serpin scaffold and reactive centre loop length
Authors: Bottomley, SP Stone, SR
Citation: Sp. Bottomley et Sr. Stone, Protein engineering of chimeric Serpins: an investigation into effects of the serpin scaffold and reactive centre loop length, PROTEIN ENG, 11(12), 1998, pp. 1243-1247
Risultati: 1-20 |