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Results: 1-13 |
Results: 13
Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA : DNA
Authors: Sarafianos, SG Das, K Tantillo, C Clark, AD Ding, J Whitcomb, JM Boyer, PL Hughes, SH Arnold, E
Citation: Sg. Sarafianos et al., Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA : DNA, EMBO J, 20(6), 2001, pp. 1449-1461
The basic loop of the RNase H domain of MLV RT is important both for RNaseH and for polymerase activity
Authors: Boyer, PL Gao, HQ Frank, P Clark, PK Hughes, SH
Citation: Pl. Boyer et al., The basic loop of the RNase H domain of MLV RT is important both for RNaseH and for polymerase activity, VIROLOGY, 282(1), 2001, pp. 206-213
Cross-linking of the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase to template-primer
Authors: Peletskaya, EN Boyer, PL Kogon, AA Clark, P Kroth, H Sayer, JM Jerina, DM Hughes, SH
Citation: En. Peletskaya et al., Cross-linking of the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase to template-primer, J VIROLOGY, 75(19), 2001, pp. 9435-9445
YADD mutants of human immunodeficiency virus type 1 and Moloney murine leukemia virus reverse transcriptase are resistant to lamivudine triphosphate (3TCTP) in vitro
Authors: Boyer, PL Gao, HQ Clark, PK Sarafianos, SG Arnold, E Hughes, SH
Citation: Pl. Boyer et al., YADD mutants of human immunodeficiency virus type 1 and Moloney murine leukemia virus reverse transcriptase are resistant to lamivudine triphosphate (3TCTP) in vitro, J VIROLOGY, 75(14), 2001, pp. 6321-6328
Replication of phenotypically mixed human immunodeficiency virus type 1 virions containing catalytically active and catalytically inactive reverse transcriptase
Authors: Julias, JG Ferris, AL Boyer, PL Hughes, SH
Citation: Jg. Julias et al., Replication of phenotypically mixed human immunodeficiency virus type 1 virions containing catalytically active and catalytically inactive reverse transcriptase, J VIROLOGY, 75(14), 2001, pp. 6537-6546
Selective excision of AZTMP by drug-resistant human immunodeficiency virusreverse transcriptase
Authors: Boyer, PL Sarafianos, SG Arnold, E Hughes, SH
Citation: Pl. Boyer et al., Selective excision of AZTMP by drug-resistant human immunodeficiency virusreverse transcriptase, J VIROLOGY, 75(10), 2001, pp. 4832-4842
The Lys103Asn mutation of HIV-1 RT: A novel mechanism of drug resistance
Authors: Hsiou, Y Ding, JP Das, K Clark, AD Boyer, PL Lewi, P Janssen, PAJ Kleim, JP Rosner, M Hughes, SH Arnold, E
Citation: Y. Hsiou et al., The Lys103Asn mutation of HIV-1 RT: A novel mechanism of drug resistance, J MOL BIOL, 309(2), 2001, pp. 437-445
Analysis of mutations at positions 115 and 116 in the dNTP binding site ofHIV-1 reverse transcriptase
Authors: Boyer, PL Sarafianos, SG Arnold, E Hughes, SH
Citation: Pl. Boyer et al., Analysis of mutations at positions 115 and 116 in the dNTP binding site ofHIV-1 reverse transcriptase, P NAS US, 97(7), 2000, pp. 3056-3061
Effects of amino acid substitutions at position 115 on the fidelity of human immunodeficiency virus type 1 reverse transcriptase
Authors: Boyer, PL Hughes, SH
Citation: Pl. Boyer et Sh. Hughes, Effects of amino acid substitutions at position 115 on the fidelity of human immunodeficiency virus type 1 reverse transcriptase, J VIROLOGY, 74(14), 2000, pp. 6494-6500
The role of steric hindrance in 3TC resistance of human immunodeficiency virus type-1 reverse transcriptase
Authors: Gao, HQ Boyer, PL Sarafianos, SG Arnold, E Hughes, SH
Citation: Hq. Gao et al., The role of steric hindrance in 3TC resistance of human immunodeficiency virus type-1 reverse transcriptase, J MOL BIOL, 300(2), 2000, pp. 403-418
Touching the heart of HIV-1 drug resistance: the fingers close down on thedNTP at the polymerase active site
Authors: Sarafianos, SG Das, K Ding, JP Boyer, PL Hughes, SH Arnold, E
Citation: Sg. Sarafianos et al., Touching the heart of HIV-1 drug resistance: the fingers close down on thedNTP at the polymerase active site, CHEM BIOL, 6(5), 1999, pp. R137-R146
Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves sterichindrance with beta-branched amino acids
Authors: Sarafianos, SG Das, K Clark, AD Ding, JP Boyer, PL Hughes, SH Arnold, E
Citation: Sg. Sarafianos et al., Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves sterichindrance with beta-branched amino acids, P NAS US, 96(18), 1999, pp. 10027-10032
Analysis of amino insertion mutations in the fingers subdomain of HIV-1 reverse transcriptase
Authors: Boyer, PL Lisziewicz, J Lori, F Hughes, SH
Citation: Pl. Boyer et al., Analysis of amino insertion mutations in the fingers subdomain of HIV-1 reverse transcriptase, J MOL BIOL, 286(4), 1999, pp. 995-1008
Risultati: 1-13 |