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Results: 1-25 |
Results: 25
Alterations in lipoxygenase and cyclooxygenase-2 catalytic activity and mRNA expression in prostate carcinoma
Authors: Shappell, SB Manning, S Boeglin, WE Guan, YF Roberts, RL Davis, L Olson, SJ Jack, GS Coffey, CS Wheeler, TM Breyer, MD Brash, AR
Citation: Sb. Shappell et al., Alterations in lipoxygenase and cyclooxygenase-2 catalytic activity and mRNA expression in prostate carcinoma, NEOPLASIA, 3(4), 2001, pp. 287-303
The origin of 15R-prostaglandins in the Caribbean coral Plexaura homomalla: Molecular cloning and expression of a novel cyclooxygenase
Authors: Valmsen, K Jarving, I Boeglin, WE Varvas, K Koljak, R Pehk, T Brash, AR Samel, N
Citation: K. Valmsen et al., The origin of 15R-prostaglandins in the Caribbean coral Plexaura homomalla: Molecular cloning and expression of a novel cyclooxygenase, P NAS US, 98(14), 2001, pp. 7700-7705
15-lipoxygenase-2 expression in benign and neoplastic sebaceous glands andother cutaneous adnexa
Authors: Shappell, SB Keeney, DS Zhang, J Page, R Olson, SJ Brash, AR
Citation: Sb. Shappell et al., 15-lipoxygenase-2 expression in benign and neoplastic sebaceous glands andother cutaneous adnexa, J INVES DER, 117(1), 2001, pp. 36-43
Arachidonic acid as a bioactive molecule
Authors: Brash, AR
Citation: Ar. Brash, Arachidonic acid as a bioactive molecule, J CLIN INV, 107(11), 2001, pp. 1339-1345
Two distinct pathways of formation of 4-hydroxynonenal. Mechanisms of non-enzymatic transformation of the 9- and 13-hydroperoxides of linoleic acid to 4-hydroxyalkenals. (vol 276, pg 20831, 2001)
Authors: Schneider, C Tallman, KA Porter, NA Brash, AR
Citation: C. Schneider et al., Two distinct pathways of formation of 4-hydroxynonenal. Mechanisms of non-enzymatic transformation of the 9- and 13-hydroperoxides of linoleic acid to 4-hydroxyalkenals. (vol 276, pg 20831, 2001), J BIOL CHEM, 276(34), 2001, pp. 32392-32392
Two distinct pathways of formation of 4-hydroxynonenal - Mechanisms of nonenzymatic transformation of the 9-and 13-hydroperoxides of linoleic acid to4-hydroxyalkenals
Authors: Schneider, C Tallman, KA Porter, NA Brash, AR
Citation: C. Schneider et al., Two distinct pathways of formation of 4-hydroxynonenal - Mechanisms of nonenzymatic transformation of the 9-and 13-hydroperoxides of linoleic acid to4-hydroxyalkenals, J BIOL CHEM, 276(24), 2001, pp. 20831-20838
The basis of prostaglandin synthesis in coral - Molecular cloning and expression of a cyclooxygenase from the Arctic soft coral Gersemia fruticosa
Authors: Koljak, R Jarving, I Kurg, R Boeglin, WE Varvas, K Valmsen, K Ustav, M Brash, AR Samel, N
Citation: R. Koljak et al., The basis of prostaglandin synthesis in coral - Molecular cloning and expression of a cyclooxygenase from the Arctic soft coral Gersemia fruticosa, J BIOL CHEM, 276(10), 2001, pp. 7033-7040
15S-hydroxyeicosatetraenoic acid activates peroxisome proliferator-activated receptor gamma and inhibits proliferation in PC3 prostate carcinoma cells
Authors: Shappell, SB Gupta, RA Manning, S Whitehead, R Boeglin, WE Schneider, C Case, T Price, J Jack, GS Wheeler, TM Matusik, RJ Brash, AR DuBois, RN
Citation: Sb. Shappell et al., 15S-hydroxyeicosatetraenoic acid activates peroxisome proliferator-activated receptor gamma and inhibits proliferation in PC3 prostate carcinoma cells, CANCER RES, 61(2), 2001, pp. 497-503
Characterization of the coral allene oxide synthase active site with UV-visible absorption, magnetic circular dichroism, and electron paramagnetic resonance spectroscopy: Evidence for tyrosinate ligation to the ferric enzymeheme iron
Authors: Abraham, BD Sono, M Boutaud, O Shriner, A Dawson, JH Brash, AR Gaffney, BJ
Citation: Bd. Abraham et al., Characterization of the coral allene oxide synthase active site with UV-visible absorption, magnetic circular dichroism, and electron paramagnetic resonance spectroscopy: Evidence for tyrosinate ligation to the ferric enzymeheme iron, BIOCHEM, 40(7), 2001, pp. 2251-2259
Site-directed mutagenesis studies on a putative fifth iron ligand of mouse8S-lipoxygenase: Retention of catalytic activity on mutation of serine-558to asparagine, histidine, or alanine
Authors: Jisaka, M Boeglin, WE Kim, RB Brash, AR
Citation: M. Jisaka et al., Site-directed mutagenesis studies on a putative fifth iron ligand of mouse8S-lipoxygenase: Retention of catalytic activity on mutation of serine-558to asparagine, histidine, or alanine, ARCH BIOCH, 386(2), 2001, pp. 136-142
Detection and cellular localization of 12R-lipoxygenase in human tonsils
Authors: Schneider, C Keeney, DS Boeglin, WE Brash, AR
Citation: C. Schneider et al., Detection and cellular localization of 12R-lipoxygenase in human tonsils, ARCH BIOCH, 386(2), 2001, pp. 268-274
Biogenesis of volatile aldehydes from fatty acid hydroperoxides: Molecularcloning of a hydroperoxide lyase (CYP74C) with specificity for both the 9-and 13-hydroperoxides of linoleic and linolenic acids
Authors: Tijet, N Schneider, C Muller, BL Brash, AR
Citation: N. Tijet et al., Biogenesis of volatile aldehydes from fatty acid hydroperoxides: Molecularcloning of a hydroperoxide lyase (CYP74C) with specificity for both the 9-and 13-hydroperoxides of linoleic and linolenic acids, ARCH BIOCH, 386(2), 2001, pp. 281-289
8S-lipoxygenase products activate peroxisome proliferator-activated receptor alpha and induce differentiation in murine keratinocytes
Authors: Muga, SJ Thuillier, P Pavone, A Rundhaug, JE Boeglin, WE Jisaka, M Brash, AR Fischer, SM
Citation: Sj. Muga et al., 8S-lipoxygenase products activate peroxisome proliferator-activated receptor alpha and induce differentiation in murine keratinocytes, CELL GROWTH, 11(8), 2000, pp. 447-454
Reduced 15-lipoxygenase-2 immunostaining in prostate adenocarcinoma: Correlation with grade and expression in high-grade prostatic intraepithelial neoplasia
Authors: Jack, GS Brash, AR Olson, SJ Manning, S Coffey, CS Smith, JA Shappell, SB
Citation: Gs. Jack et al., Reduced 15-lipoxygenase-2 immunostaining in prostate adenocarcinoma: Correlation with grade and expression in high-grade prostatic intraepithelial neoplasia, HUMAN PATH, 31(9), 2000, pp. 1146-1154
Autoxidation of methyl linoleate: Identification of the bis-allylic 11-hydroperoxide
Authors: Brash, AR
Citation: Ar. Brash, Autoxidation of methyl linoleate: Identification of the bis-allylic 11-hydroperoxide, LIPIDS, 35(9), 2000, pp. 947-952
Purification, molecular cloning, and expression of the gene encoding fattyacid 13-hydroperoxide lyase from guava fruit (Psidium guajava)
Authors: Tijet, N Waspi, U Gaskin, DJH Hunziker, P Muller, BL Vulfson, EN Slusarenko, A Brash, AR Whitehead, IM
Citation: N. Tijet et al., Purification, molecular cloning, and expression of the gene encoding fattyacid 13-hydroperoxide lyase from guava fruit (Psidium guajava), LIPIDS, 35(7), 2000, pp. 709-720
Stereospecificity of hydrogen abstraction in the conversion of arachidonicacid to 15R-HETE by aspirin-treated cyclooxygenase-2 - Implications for the alignment of substrate in the active site
Authors: Schneider, C Brash, AR
Citation: C. Schneider et Ar. Brash, Stereospecificity of hydrogen abstraction in the conversion of arachidonicacid to 15R-HETE by aspirin-treated cyclooxygenase-2 - Implications for the alignment of substrate in the active site, J BIOL CHEM, 275(7), 2000, pp. 4743-4746
Identification of amino acid determinants of the positional specificity ofmouse 8S-lipoxygenase and human 15S-lipoxygenase-2
Authors: Jisaka, M Kim, RB Boeglin, WE Brash, AR
Citation: M. Jisaka et al., Identification of amino acid determinants of the positional specificity ofmouse 8S-lipoxygenase and human 15S-lipoxygenase-2, J BIOL CHEM, 275(2), 2000, pp. 1287-1293
Enantiomeric separation of hydroxy eicosanoids by chiral column chromatography: Effect of the alcohol modifier
Authors: Schneider, C Boeglin, WE Brash, AR
Citation: C. Schneider et al., Enantiomeric separation of hydroxy eicosanoids by chiral column chromatography: Effect of the alcohol modifier, ANALYT BIOC, 287(1), 2000, pp. 186-189
Synthesis and applications of stereospecifically H-3-labeled arachidonic acids as mechanistic probes for lipoxygenase and cyclooxygenase catalysis
Authors: Schneider, C Boeglin, WE Lai, S Cha, JK Brash, AR
Citation: C. Schneider et al., Synthesis and applications of stereospecifically H-3-labeled arachidonic acids as mechanistic probes for lipoxygenase and cyclooxygenase catalysis, ANALYT BIOC, 284(1), 2000, pp. 125-135
Purification and catalytic activities of the two domains of the allene oxide synthase-lipoxygenase fusion protein of the coral Plexaura homomalla
Authors: Boutaud, O Brash, AR
Citation: O. Boutaud et Ar. Brash, Purification and catalytic activities of the two domains of the allene oxide synthase-lipoxygenase fusion protein of the coral Plexaura homomalla, J BIOL CHEM, 274(47), 1999, pp. 33764-33770
Lipoxygenases: Occurrence, functions, catalysis, and acquisition of substrate
Authors: Brash, AR
Citation: Ar. Brash, Lipoxygenases: Occurrence, functions, catalysis, and acquisition of substrate, J BIOL CHEM, 274(34), 1999, pp. 23679-23682
Evidence of a cyclooxygenase-related prostaglandin synthesis in coral - The allene oxide pathway is not involved in prostaglandin biosynthesis
Authors: Varvas, K Jarving, I Koljak, R Valmsen, K Brash, AR Samel, N
Citation: K. Varvas et al., Evidence of a cyclooxygenase-related prostaglandin synthesis in coral - The allene oxide pathway is not involved in prostaglandin biosynthesis, J BIOL CHEM, 274(15), 1999, pp. 9923-9929
15-lipoxygenase-2 (15-LOX-2) is expressed in benign prostatic epithelium and reduced in prostate adenocarcinoma
Authors: Shappell, SB Boeglin, WE Olson, SJ Kasper, S Brash, AR
Citation: Sb. Shappell et al., 15-lipoxygenase-2 (15-LOX-2) is expressed in benign prostatic epithelium and reduced in prostate adenocarcinoma, AM J PATH, 155(1), 1999, pp. 235-245
Mechanism of the rearrangement of vinyl allene oxide to 2-cyclopenten-1-one
Authors: Hess, BA Smentek, L Brash, AR Cha, JK
Citation: Ba. Hess et al., Mechanism of the rearrangement of vinyl allene oxide to 2-cyclopenten-1-one, J AM CHEM S, 121(23), 1999, pp. 5603-5604
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