Authors:
Smaill, JB
Showalter, HDH
Zhou, HR
Bridges, AJ
McNamara, DJ
Fry, DW
Nelson, JM
Sherwood, V
Vincent, PW
Roberts, BJ
Elliott, WL
Denny, WA
Citation: Jb. Smaill et al., Tyrosine kinase inhibitors. 18. 6-substituted 4-anilinoquinazolines and 4-anilinopyrido [3,4-d]pyrimidines as soluble, irreversible inhibitors of theepidermal growth factor receptor, J MED CHEM, 44(3), 2001, pp. 429-440
Authors:
Vincent, PW
Bridges, AJ
Dykes, DJ
Fry, DW
Leopold, WR
Patmore, SJ
Roberts, BJ
Rose, S
Sherwood, V
Zhou, HR
Elliott, WL
Citation: Pw. Vincent et al., Anticancer efficacy of the irreversible EGFr tyrosine kinase inhibitor PD 0169414 against human tumor xenografts, CANC CHEMOT, 45(3), 2000, pp. 231-238
Authors:
Smaill, JB
Rewcastle, GW
Bridges, AJ
Zhou, HR
Showalter, HDH
Fry, DW
Nelson, JM
Sherwood, V
Elliott, WL
Vincent, PW
DeJohn, DE
Loo, JA
Greis, KD
Chan, OH
Reyner, EL
Lipka, E
Denny, WA
Citation: Jb. Smaill et al., Tyrosine kinase inhibitors. 17. Irreversible inhibitors of the epidermal growth factor receptor: 4-(phenylamino)quinazoline- and 4-(phenylamino)pyrido[3,2-d]-pyrimidine-6-acrylamides bearing additional solubilizing functions(vol 43, pg 1380, 2000), J MED CHEM, 43(16), 2000, pp. 3199-3199
Authors:
Ritland, SR
Gendler, SJ
Burgart, LJ
Fry, DW
Nelson, JM
Bridges, AJ
Andress, L
Karnes, WE
Citation: Sr. Ritland et al., Inhibition of epidermal growth factor receptor tyrosine kinase fails to suppress adenoma formation in Apc(Min) mice but induces duodenal injury, CANCER RES, 60(17), 2000, pp. 4678-4681
Citation: Aj. Bridges, The rationale and strategy used to develop a series of highly potent, irreversible, inhibitors of the epidermal growth factor receptor family of tyrosine kinases, CURR MED CH, 6(9), 1999, pp. 825-843
Authors:
Wilson, RB
Gluck, OS
Tesser, JRP
Rice, JC
Meyer, A
Bridges, AJ
Citation: Rb. Wilson et al., Antipolymer antibody reactivity in a subset of patients with fibromyalgia correlates with severity, J RHEUMATOL, 26(2), 1999, pp. 402-407
Authors:
Showalter, HDH
Bridges, AJ
Zhou, HR
Sercel, AD
McMichael, A
Fry, DW
Citation: Hdh. Showalter et al., Tyrosine kinase inhibitors. 16. 6,5,6-tricyclic benzothieno [3,2-d]pyrimidines and pyrimido[5,4-b]- and -[4,5-b]indoles as potent inhibitors of the epidermal growth factor receptor tyrosine kinase, J MED CHEM, 42(26), 1999, pp. 5464-5474
Authors:
Smaill, JB
Palmer, BD
Rewcastle, GW
Denny, WA
McNamara, DJ
Dobrusin, EM
Bridges, AJ
Zhou, HR
Showalter, HDH
Winters, RT
Leopold, WR
Fry, DW
Nelson, JM
Slintak, V
Elliot, WL
Roberts, BJ
Vincent, PW
Patmore, SJ
Citation: Jb. Smaill et al., Tyrosine kinase inhibitors. 15. 4-(phenylamino)quinazoline and 4-(phenylamino)pyrido[d] pyrimidine acrylamides as irreversible inhibitors of the ATP binding site of the epidermal growth factor receptor, J MED CHEM, 42(10), 1999, pp. 1803-1815