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Results: 1-12 |
Results: 12
Structure-function aspects and inhibitor design of type 5 17 beta-hydroxysteroid dehydrogenase (AKR1C3)
Authors: Penning, TM Burczynski, ME Jez, JM Lin, HK Ma, HC Moore, M Ratnam, K Palackal, N
Citation: Tm. Penning et al., Structure-function aspects and inhibitor design of type 5 17 beta-hydroxysteroid dehydrogenase (AKR1C3), MOL C ENDOC, 171(1-2), 2001, pp. 137-149
Cytochrome P450 induction in rat hepatocytes assessed by quantitative real-time reverse-transcription polymerase chain reaction and the RNA invasive cleavage assay
Authors: Burczynski, ME McMillian, M Parker, JB Bryant, S Leone, A Grant, ER Thorne, JM Zhong, Z Zivin, RA Johnson, MD
Citation: Me. Burczynski et al., Cytochrome P450 induction in rat hepatocytes assessed by quantitative real-time reverse-transcription polymerase chain reaction and the RNA invasive cleavage assay, DRUG META D, 29(9), 2001, pp. 1243-1250
The reactive oxygen species- and Michael acceptor-inducible human aldo-keto reductase AKR1C1 reduces the alpha,beta-unsaturated aldehyde 4-hydroacy-2-nonenal to 1,4-dihydroxy-2-nonene
Authors: Burczynski, ME Sridhar, GR Palackal, NT Penning, TM
Citation: Me. Burczynski et al., The reactive oxygen species- and Michael acceptor-inducible human aldo-keto reductase AKR1C1 reduces the alpha,beta-unsaturated aldehyde 4-hydroacy-2-nonenal to 1,4-dihydroxy-2-nonene, J BIOL CHEM, 276(4), 2001, pp. 2890-2897
Metabolic activation of polycyclic aromatic hydrocarbon trans-dihydrodiolsby ubiquitously expressed aldehyde reductase (AKR1A1)
Authors: Palackal, NT Burczynski, ME Harvey, RG Penning, TM
Citation: Nt. Palackal et al., Metabolic activation of polycyclic aromatic hydrocarbon trans-dihydrodiolsby ubiquitously expressed aldehyde reductase (AKR1A1), CHEM-BIO IN, 130(1-3), 2001, pp. 815-824
The ubiquitous aldehyde reductase (AKR1A1) oxidizes proximate carcinogen trans-dihydrodiols to o-quinones: Potential role in polycyclic aromatic hydrocarbon activation
Authors: Palackal, NT Burczynski, ME Harvey, RG Penning, TM
Citation: Nt. Palackal et al., The ubiquitous aldehyde reductase (AKR1A1) oxidizes proximate carcinogen trans-dihydrodiols to o-quinones: Potential role in polycyclic aromatic hydrocarbon activation, BIOCHEM, 40(36), 2001, pp. 10901-10910
Toxicogenomics-based discrimination of toxic mechanism in HepG2 human hepatoma cells
Authors: Burczynski, ME McMillian, M Ciervo, J Li, L Parker, JB Dunn, RT Hicken, S Farr, S Johnson, MD
Citation: Me. Burczynski et al., Toxicogenomics-based discrimination of toxic mechanism in HepG2 human hepatoma cells, TOXICOL SCI, 58(2), 2000, pp. 399-415
Human 3 alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of thealdo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sexhormones
Authors: Penning, TM Burczynski, ME Jez, JM Hung, CF Lin, HK Ma, HC Moore, M Palackal, N Ratnam, K
Citation: Tm. Penning et al., Human 3 alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of thealdo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sexhormones, BIOCHEM J, 351, 2000, pp. 67-77
Genotoxic polycyclic aromatic hydrocarbon ortho-quinones generated by aldo-keto reductases induce CYP1A1 via nuclear translocation of the aryl hydrocarbon receptor
Authors: Burczynski, ME Penning, TM
Citation: Me. Burczynski et Tm. Penning, Genotoxic polycyclic aromatic hydrocarbon ortho-quinones generated by aldo-keto reductases induce CYP1A1 via nuclear translocation of the aryl hydrocarbon receptor, CANCER RES, 60(4), 2000, pp. 908-915
Polycyclic aromatic hydrocarbon trans-dihydrodiol specificity of four recombinant human dihydrodiol dehydrogenase isoforms
Authors: Burczynski, ME Palackal, NT Harvey, RG Penning, TM
Citation: Me. Burczynski et al., Polycyclic aromatic hydrocarbon trans-dihydrodiol specificity of four recombinant human dihydrodiol dehydrogenase isoforms, POLYCYCL AR, 16(1-4), 1999, pp. 205-214
Dihydrodiol dehydrogenases and polycyclic aromatic hydrocarbon activation:Generation of reactive and redox active o-quinones
Authors: Penning, TM Burczynski, ME Hung, CF McCoull, KD Palackal, NT Tsuruda, LS
Citation: Tm. Penning et al., Dihydrodiol dehydrogenases and polycyclic aromatic hydrocarbon activation:Generation of reactive and redox active o-quinones, CHEM RES T, 12(1), 1999, pp. 1-18
Isoform-specific induction of a human aldo-keto reductase by polycyclic aromatic hydrocarbons (PAHs), electrophiles, and oxidative stress: Implications for the alternative pathway of PAH activation catalyzed by human dihydrodiol dehydrogenase
Authors: Burczynski, ME Lin, HK Penning, TM
Citation: Me. Burczynski et al., Isoform-specific induction of a human aldo-keto reductase by polycyclic aromatic hydrocarbons (PAHs), electrophiles, and oxidative stress: Implications for the alternative pathway of PAH activation catalyzed by human dihydrodiol dehydrogenase, CANCER RES, 59(3), 1999, pp. 607-614
Expression and characterization of four recombinant human dihydrodiol dehydrogenase isoforms: Oxidation of trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene to the activated o-quinone metabolite benzo[a]pyrene-7,8-dione (vol 37,pg 6781, 1998)
Authors: Burczynski, ME Harvey, RG Penning, TM
Citation: Me. Burczynski et al., Expression and characterization of four recombinant human dihydrodiol dehydrogenase isoforms: Oxidation of trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene to the activated o-quinone metabolite benzo[a]pyrene-7,8-dione (vol 37,pg 6781, 1998), BIOCHEM, 38(32), 1999, pp. 10626-10626
Risultati: 1-12 |