Authors:
Trotter, BW
Quigley, AG
Lumma, WC
Sisko, JT
Walsh, ES
Hamann, CS
Robinson, RG
Bhimnathwala, H
Kolodin, DG
Zheng, W
Buser, CA
Huber, HE
Lobell, RB
Kohl, NE
Williams, TM
Graham, SL
Dinsmore, CJ
Citation: Bw. Trotter et al., 2-Arylindole-3-acetamides: FPP-competitive inhibitors of farnesyl protein transferase, BIOORG MED, 11(7), 2001, pp. 865-869
Authors:
Beshore, DC
Bell, IM
Dinsmore, CJ
Homnick, CF
Culberson, JC
Robinson, RG
Fernandes, C
Walsh, ES
Abrams, MT
Bhimnathwala, HG
Davide, JP
Ellis-Hutchings, MS
Huber, HA
Koblan, KS
Buser, CA
Kohl, NE
Lobell, RB
Chen, IW
McLoughlin, DA
Olah, TV
Graham, SL
Hartman, GD
Williams, TM
Citation: Dc. Beshore et al., Evaluation of amino acid-based linkers in potent macrocyclic inhibitors offarnesyl-protein transferase, BIOORG MED, 11(14), 2001, pp. 1817-1821
Authors:
Bergman, JM
Abrams, MT
Davide, JP
Greenberg, IB
Robinson, RG
Buser, CA
Huber, HE
Koblan, KS
Kohl, NE
Lobell, RB
Graham, SL
Hartman, GD
Williams, TM
Dinsmore, CJ
Citation: Jm. Bergman et al., Aryloxy substituted N-arylpiperazinones as dual inhibitors of farnesyltransferase and geranylgeranyltransferase-I, BIOORG MED, 11(11), 2001, pp. 1411-1415
Authors:
Bell, IM
Gallicchio, SN
Abrams, M
Beshore, DC
Buser, CA
Culberson, JC
Davide, J
Ellis-Hutchings, M
Fernandes, C
Gibbs, JB
Graham, SL
Hartman, GD
Heimbrook, DC
Homnick, CF
Huff, JR
Kassahun, K
Koblan, KS
Kohl, NE
Lobell, RB
Lynch, JJ
Miller, PA
Omer, CA
Rodrigues, AD
Walsh, ES
Williams, TM
Citation: Im. Bell et al., Design and biological activity of (S)-4-(5-{[1-(3-chlorobenzyl)-2-oxopyrrolidin-3-ylamino]methyl}imidazol-1-ylmethyl)benzonitrile, a 3-aminopyrrolidinone farnesyltransferase inhibitor with excellent cell potency, J MED CHEM, 44(18), 2001, pp. 2933-2949
Authors:
Huber, HE
Robinson, RG
Watkins, A
Nahas, DD
Abrams, MT
Buser, CA
Lobell, RB
Patrick, D
Anthony, NJ
Dinsmore, CJ
Graham, SL
Hartman, GD
Lumma, WC
Williams, TM
Heimbrook, DC
Citation: He. Huber et al., Anions modulate the potency of geranylgeranyl-protein transferase I inhibitors, J BIOL CHEM, 276(27), 2001, pp. 24457-24465
Authors:
Buser, CA
Dinsmore, CJ
Fernandes, C
Greenberg, I
Hamilton, K
Mosser, SD
Walsh, ES
Williams, TM
Koblan, KS
Citation: Ca. Buser et al., High-performance liquid chromatography/mass spectrometry characterization of Ki4B-Ras in PSN-1 cells treated with the prenyltransferase inhibitor L-778,123, ANALYT BIOC, 290(1), 2001, pp. 126-137