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Results: 1-25 | 26-50 | 51-53
Results: 1-25/53
A PHASE-I AND PHARMACOKINETIC STUDY OF LY231514, THE MULTITARGETED ANTIFOLATE
Authors: MCDONALD AC VASEY PA ADAMS L WALLING J WOODWORTH JR ABRAHAMS T MCCARTHY S BAILEY NP SIDDIQUI N LIND MJ CALVERT AH TWELVES CJ CASSIDY J KAYE SB
Citation: Ac. Mcdonald et al., A PHASE-I AND PHARMACOKINETIC STUDY OF LY231514, THE MULTITARGETED ANTIFOLATE, Clinical cancer research, 4(3), 1998, pp. 605-610
A PHASE-I AND PHARMACOKINETIC STUDY OF LY231514, THE MULTITARGETED ANTIFOLATE
Authors: MCDONALD AC VASEY PA ADAMS L WALLING J WOODWORTH JR ABRAHAMS T MCCARTHY S BAILEY NP SIDDIQUI N LIND MJ CALVERT AH TWELVES CJ CASSIDY J KAYE SB
Citation: Ac. Mcdonald et al., A PHASE-I AND PHARMACOKINETIC STUDY OF LY231514, THE MULTITARGETED ANTIFOLATE, Clinical cancer research, 4(3), 1998, pp. 605-610
DIPYRIDAMOLE POTENTIATES ANTIPURINE ANTIFOLATE ACTIVITY IN THE PRESENCE OF HYPOXANTHINE IN TUMOR-CELLS BUT NOT IN NORMAL-TISSUES IN-VITRO
Authors: MARSHMAN E NEWELL DR CALVERT AH DICKINSON AM PATEL HRH CAMPBELL FC CURTIN NJ
Citation: E. Marshman et al., DIPYRIDAMOLE POTENTIATES ANTIPURINE ANTIFOLATE ACTIVITY IN THE PRESENCE OF HYPOXANTHINE IN TUMOR-CELLS BUT NOT IN NORMAL-TISSUES IN-VITRO, Clinical cancer research, 4(11), 1998, pp. 2895-2902
EVIDENCE FOR THE DURATION OF THE ANTIFOLATE ACTION OF THE THYMIDYLATESYNTHASE (TS) INHIBITOR ZD9331 USING PLASMA DURD AS A SURROGATE MARKER OF ENZYME-INHIBITION
Authors: JACKMAN AL MITCHELL F LYNN S AHERNE GW REES C CALVERT AH JUDSON IR DIAB S MAYNE K SMITH M
Citation: Al. Jackman et al., EVIDENCE FOR THE DURATION OF THE ANTIFOLATE ACTION OF THE THYMIDYLATESYNTHASE (TS) INHIBITOR ZD9331 USING PLASMA DURD AS A SURROGATE MARKER OF ENZYME-INHIBITION, Annals of oncology, 9, 1998, pp. 604-604
PHASE-I TRIAL OF ZD9331 GIVEN AS A 30 MINUTE INFUSION ON DAYS 1 AND 8WITH CYCLES REPEATED EVERY 3 WEEKS
Authors: REES C BEALE P PLUMMER R HIGHLEY M CALVERT AH JUDSON I SMITH R HUTCHISON M AVERBUCH S MAYNE K
Citation: C. Rees et al., PHASE-I TRIAL OF ZD9331 GIVEN AS A 30 MINUTE INFUSION ON DAYS 1 AND 8WITH CYCLES REPEATED EVERY 3 WEEKS, Annals of oncology, 9, 1998, pp. 628-628
2-PHENYLBENZIMIDAZOLE-4-CARBOXAMIDES ARE POTENT INHIBITORS OF THE DNA-REPAIR ENZYME POLY(ADP-RIBOSE)-POLYMERASE (PARP)
Authors: ALMASSY R BOWMAN K CALVERT AH CURTIN NJ GOLDING BT HOSTOMSKA Z HOSTOMSKY Z GRIFFIN RJ MAEGLEY K NEWELL DR SRINIVASAN S WHITE AW WEBBER S
Citation: R. Almassy et al., 2-PHENYLBENZIMIDAZOLE-4-CARBOXAMIDES ARE POTENT INHIBITORS OF THE DNA-REPAIR ENZYME POLY(ADP-RIBOSE)-POLYMERASE (PARP), Annals of oncology, 9, 1998, pp. 116-116
PHARMACOKINETIC INTERACTIONS IN A PHASE-I STUDY OF NOLATREXED (AG337,THYMITAQ(TM)) AND PACLITAXEL IN PATIENTS WITH ADVANCED SOLID TUMORS
Authors: HUGHES AN GRIFFIN MJ CALVERT AH JOHNSTON A KERR B LEE C NEWELL DR BODDY AV
Citation: An. Hughes et al., PHARMACOKINETIC INTERACTIONS IN A PHASE-I STUDY OF NOLATREXED (AG337,THYMITAQ(TM)) AND PACLITAXEL IN PATIENTS WITH ADVANCED SOLID TUMORS, Annals of oncology, 9, 1998, pp. 463-463
O-6-ALKYLGUANINES AS SELECTIVE INHIBITORS OF CYCLIN-DEPENDENT KINASES
Authors: GRANT S BOYLE F CALVERT AH CURTIN NJ ENDICOTT J GOLDING BT GRIFFIN RJ JOHNSON LN NEWELL DR NOBLE MEM ROBSON C
Citation: S. Grant et al., O-6-ALKYLGUANINES AS SELECTIVE INHIBITORS OF CYCLIN-DEPENDENT KINASES, Annals of oncology, 9, 1998, pp. 523-523
POTENTIATION OF THE IN-VITRO ACTIVITY OF THE MULTITARGETED ANTIFOLATEMTA (LY231514) BY DIPYRIDAMOLE
Authors: SMITH PG NEWELL DR BARNES MJ CALVERT AH CURTIN NJ
Citation: Pg. Smith et al., POTENTIATION OF THE IN-VITRO ACTIVITY OF THE MULTITARGETED ANTIFOLATEMTA (LY231514) BY DIPYRIDAMOLE, Annals of oncology, 9, 1998, pp. 588-588
DIPYRIDAMOLE SELECTIVELY POTENTIATES ANTIPURINE ANTIFOLATES IN HUMAN TUMOR-CELL LINES BUT NOT NORMAL TISSUE TARGETS OF DOSE-LIMITING TOXICITY
Authors: MARSHMAN E CALVERT AH NEWELL DR CURTIN NJ
Citation: E. Marshman et al., DIPYRIDAMOLE SELECTIVELY POTENTIATES ANTIPURINE ANTIFOLATES IN HUMAN TUMOR-CELL LINES BUT NOT NORMAL TISSUE TARGETS OF DOSE-LIMITING TOXICITY, Annals of oncology, 9, 1998, pp. 589-589
PLASMA 2'-DEOXYURIDINE (DURD) AS A SURROGATE MARKER OF THYMIDYLATE SYNTHASE (TS) INHIBITION IN PATIENTS IN PHASE-I CLINICAL-TRIALS OF THE TS INHIBITOR ZD9331
Authors: MITCHELL F LYNN S REES C JUDSON I CALVERT AH RATAIN M DIAB S ROWINSKY E MAYNE K JACKMAN AL
Citation: F. Mitchell et al., PLASMA 2'-DEOXYURIDINE (DURD) AS A SURROGATE MARKER OF THYMIDYLATE SYNTHASE (TS) INHIBITION IN PATIENTS IN PHASE-I CLINICAL-TRIALS OF THE TS INHIBITOR ZD9331, Annals of oncology, 9, 1998, pp. 614-614
PHASE-I TRIAL OF ZD9331 GIVEN AS A 30 MINUTE INFUSION ON DAYS 1 AND 8WITH CYCLES REPEATED EVERY 3 WEEKS
Authors: PLUMMER R CALVERT AH JUDSON I BEALE P REES C GOKAL S HIGHLEY M LIND M SMITH R HUTCHISON M MAYNE K
Citation: R. Plummer et al., PHASE-I TRIAL OF ZD9331 GIVEN AS A 30 MINUTE INFUSION ON DAYS 1 AND 8WITH CYCLES REPEATED EVERY 3 WEEKS, Annals of oncology, 9, 1998, pp. 617-617
PRECLINICAL AND PHASE-I CLINICAL-STUDIES WITH THE NONCLASSICAL ANTIFOLATE THYMIDYLATE SYNTHASE INHIBITOR NOLATREXED DIHYDROCHLORIDE GIVEN BY PROLONGED ADMINISTRATION IN PATIENTS WITH SOLID TUMORS
Authors: RAFI I BODDY AV CALVETE JA TAYLOR GA NEWELL DR BAILEY NP LIND MJ GREEN M HINES J JOHNSTONE A CLENDENINN N CALVERT AH
Citation: I. Rafi et al., PRECLINICAL AND PHASE-I CLINICAL-STUDIES WITH THE NONCLASSICAL ANTIFOLATE THYMIDYLATE SYNTHASE INHIBITOR NOLATREXED DIHYDROCHLORIDE GIVEN BY PROLONGED ADMINISTRATION IN PATIENTS WITH SOLID TUMORS, Journal of clinical oncology, 16(3), 1998, pp. 1131-1141
O-6-METHYLGUANINE-DNA METHYLTRANSFERASE IN PRETREATMENT TUMOR-BIOPSIES AS A PREDICTOR OF RESPONSE TO TEMOZOLOMIDE IN MELANOMA
Authors: MIDDLETON MR LUNN JM MORRIS C RUSTIN G WEDGE SR BRAMPTON MH LIND MJ LEE SM NEWELL DR BLEEHEN NM NEWLANDS ES CALVERT AH MARGISON GP THATCHER N
Citation: Mr. Middleton et al., O-6-METHYLGUANINE-DNA METHYLTRANSFERASE IN PRETREATMENT TUMOR-BIOPSIES AS A PREDICTOR OF RESPONSE TO TEMOZOLOMIDE IN MELANOMA, British Journal of Cancer, 78(9), 1998, pp. 1199-1202
CLINICAL-STUDIES WITH MTA
Authors: CALVERT AH WALLING JM
Citation: Ah. Calvert et Jm. Walling, CLINICAL-STUDIES WITH MTA, British Journal of Cancer, 78, 1998, pp. 35-40
CHEMOTHERAPY FOR OVARIAN-CANCER - A CONSENSUS STATEMENT ON STANDARD PRACTICE
Authors: ADAMS M CALVERT AH CARMICHAEL J CLARK PI COLEMAN RE EARL HM GALLAGHER CJ GANESAN TS GORE ME GRAHAM JD HARPER PG JAYSON GC KAYE SB LEDERMANN JA OSBORNE RJ PERREN TJ POOLE CJ RADFORD JA RUSTIN GJS SLEVIN ML SMYTH JF THOMAS H WILKINSON PM
Citation: M. Adams et al., CHEMOTHERAPY FOR OVARIAN-CANCER - A CONSENSUS STATEMENT ON STANDARD PRACTICE, British Journal of Cancer, 78(11), 1998, pp. 1404-1406
THE USE OF PHARMACOKINETICS TO IMPROVE THE TREATMENT OF OVARIAN-CANCER - COMBINATION PACLITAXEL (TAXOL(R))CARBOPLATIN
Authors: CALVERT AH
Citation: Ah. Calvert, THE USE OF PHARMACOKINETICS TO IMPROVE THE TREATMENT OF OVARIAN-CANCER - COMBINATION PACLITAXEL (TAXOL(R))CARBOPLATIN, International journal of gynecological cancer, 7, 1997, pp. 14-17
A PHASE-II STUDY WITH GI147211 IN OVARIAN-CANCER
Authors: WANDERS J VANOOSTEROM AT GORE M CALVERT AH HUININK WWT HANSEN HH WISSEL P HANAUSKE AR
Citation: J. Wanders et al., A PHASE-II STUDY WITH GI147211 IN OVARIAN-CANCER, European journal of cancer, 33, 1997, pp. 528-528
A REVIEW OF THE PHARMACOKINETICS AND PHARMACODYNAMICS OF COMBINATION CARBOPLATIN PACLITAXEL/
Authors: CALVERT AH
Citation: Ah. Calvert, A REVIEW OF THE PHARMACOKINETICS AND PHARMACODYNAMICS OF COMBINATION CARBOPLATIN PACLITAXEL/, Seminars in oncology, 24(1), 1997, pp. 85-90
THE RELATIONSHIP BETWEEN INTRINSIC THYMIDYLATE SYNTHASE EXPRESSION AND SENSITIVITY TO THYMITAQ(TM) IN HUMAN LEUKEMIA AND COLORECTAL-CARCINOMA CELL-LINES
Authors: ESTLIN EJ BALMANNO K CALVERT AH HALL AG LUNEC J NEWELL DR PEARSON ADJ TAYLOR GA
Citation: Ej. Estlin et al., THE RELATIONSHIP BETWEEN INTRINSIC THYMIDYLATE SYNTHASE EXPRESSION AND SENSITIVITY TO THYMITAQ(TM) IN HUMAN LEUKEMIA AND COLORECTAL-CARCINOMA CELL-LINES, British Journal of Cancer, 76(12), 1997, pp. 1579-1585
A CLINICAL AND PHARMACOKINETIC STUDY OF THE COMBINATION OF CARBOPLATIN AND PACLITAXEL FOR EPITHELIAL OVARIAN-CANCER
Authors: SIDDIQUI N BODDY AV THOMAS HD BAILEY NP ROBSON L LIND MJ CALVERT AH
Citation: N. Siddiqui et al., A CLINICAL AND PHARMACOKINETIC STUDY OF THE COMBINATION OF CARBOPLATIN AND PACLITAXEL FOR EPITHELIAL OVARIAN-CANCER, British Journal of Cancer, 75(2), 1997, pp. 287-294
ALTERNATIVELY SPLICED MDM2 TRANSCRIPTS WITH LOSS OF P53 BINDING DOMAIN SEQUENCES - TRANSFORMING ABILITY AND FREQUENT DETECTION IN HUMAN CANCER
Authors: SIGALAS I CALVERT AH ANDERSON JJ NEAL DE LUNEC J
Citation: I. Sigalas et al., ALTERNATIVELY SPLICED MDM2 TRANSCRIPTS WITH LOSS OF P53 BINDING DOMAIN SEQUENCES - TRANSFORMING ABILITY AND FREQUENT DETECTION IN HUMAN CANCER, Nature medicine, 2(8), 1996, pp. 912-917
PHASE-I STUDY OF PHARMACOLOGICALLY BASED DOSING OF CARBOPLATIN WITH FILGRASTIM SUPPORT IN WOMEN WITH EPITHELIAL OVARIAN-CANCER
Authors: LIND MJ GHAZALASWAD S GUMBRELL L FISHWICK K CRAIGS D MILLWARD MJ BAILEY NP DOREGREEN F CHAPMAN F SIMMONS D PROCTOR M OAKEY A ROBSON L MIDDLETON I MCCANN E SINHA D CALVERT AH
Citation: Mj. Lind et al., PHASE-I STUDY OF PHARMACOLOGICALLY BASED DOSING OF CARBOPLATIN WITH FILGRASTIM SUPPORT IN WOMEN WITH EPITHELIAL OVARIAN-CANCER, Journal of clinical oncology, 14(3), 1996, pp. 800-805
A SINGLE-SAMPLE ASSAY FOR THE ESTIMATION OF THE AREA UNDER THE FREE CARBOPLATIN PLASMA-CONCENTRATION VERSUS TIME CURVE
Authors: GHAZALASWAD S CALVERT AH NEWELL DR
Citation: S. Ghazalaswad et al., A SINGLE-SAMPLE ASSAY FOR THE ESTIMATION OF THE AREA UNDER THE FREE CARBOPLATIN PLASMA-CONCENTRATION VERSUS TIME CURVE, Cancer chemotherapy and pharmacology, 37(5), 1996, pp. 429-434
A PHASE-I CLINICAL-STUDY OF THE ANTIPURINE ANTIFOLATE LOMETREXOL (DDATHF) GIVEN WITH ORAL FOLIC-ACID
Authors: LAOHAVINIJ S WEDGE SR LIND MJ BAILEY N HUMPHREY A PROCTOR M CHAPMAN F SIMMONS D OAKLEY A ROBSON L GUMBRELL L TAYLOR GA THOMAS HD BODDY AV NEWELL DR CALVERT AH
Citation: S. Laohavinij et al., A PHASE-I CLINICAL-STUDY OF THE ANTIPURINE ANTIFOLATE LOMETREXOL (DDATHF) GIVEN WITH ORAL FOLIC-ACID, Investigational new drugs, 14(3), 1996, pp. 325-335
Risultati: 1-25 | 26-50 | 51-53