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Results: 26-50/124
POINT MUTATIONS IN HUMAN BETA CARDIAC MYOSIN HEAVY-CHAIN HAVE DIFFERENTIAL-EFFECTS ON SARCOMERIC STRUCTURE AND ASSEMBLY - AN ATP BINDING-SITE CHANGE DISRUPTS BOTH THICK AND THIN-FILAMENTS, WHEREAS HYPERTROPHICCARDIOMYOPATHY MUTATIONS DISPLAY NORMAL ASSEMBLY
Authors: BECKER KD GOTTSHALL KR HICKEY R PERRIARD JC CHIEN KR
Citation: Kd. Becker et al., POINT MUTATIONS IN HUMAN BETA CARDIAC MYOSIN HEAVY-CHAIN HAVE DIFFERENTIAL-EFFECTS ON SARCOMERIC STRUCTURE AND ASSEMBLY - AN ATP BINDING-SITE CHANGE DISRUPTS BOTH THICK AND THIN-FILAMENTS, WHEREAS HYPERTROPHICCARDIOMYOPATHY MUTATIONS DISPLAY NORMAL ASSEMBLY, The Journal of cell biology, 137(1), 1997, pp. 131-140
CARDIOTROPHIN 1 (CT-1) INHIBITION OF CARDIAC MYOCYTE APOPTOSIS VIA A MITOGEN-ACTIVATED PROTEIN KINASE-DEPENDENT PATHWAY - DIVERGENCE FROM DOWNSTREAM CT-1 SIGNALS FOR MYOCARDIAL-CELL HYPERTROPHY
Authors: SHENG ZL KNOWLTON K CHEN J HOSHIJIMA M BROWN JH CHIEN KR
Citation: Zl. Sheng et al., CARDIOTROPHIN 1 (CT-1) INHIBITION OF CARDIAC MYOCYTE APOPTOSIS VIA A MITOGEN-ACTIVATED PROTEIN KINASE-DEPENDENT PATHWAY - DIVERGENCE FROM DOWNSTREAM CT-1 SIGNALS FOR MYOCARDIAL-CELL HYPERTROPHY, The Journal of biological chemistry, 272(9), 1997, pp. 5783-5791
THE MEKK-JNK PATHWAY IS STIMULATED BY ALPHA(1)-ADRENERGIC RECEPTOR AND RAS ACTIVATION AND IS ASSOCIATED WITH IN-VITRO AND IN-VIVO CARDIAC-HYPERTROPHY
Authors: RAMIREZ MT SAH VP ZHAO XL HUNTER JJ CHIEN KR BROWN JH
Citation: Mt. Ramirez et al., THE MEKK-JNK PATHWAY IS STIMULATED BY ALPHA(1)-ADRENERGIC RECEPTOR AND RAS ACTIVATION AND IS ASSOCIATED WITH IN-VITRO AND IN-VIVO CARDIAC-HYPERTROPHY, The Journal of biological chemistry, 272(22), 1997, pp. 14057-14061
HF1-B IS REQUIRED FOR NORMAL PITUITARY DEVELOPMENT AND MARKS THE MATURATION OF CARDIAC VENTRICULAR LINEAGES IN TO PURKINJE-CELLS
Authors: NGUYENTRAN VTB KUBALAK SW MCEVILLY RJ WOLLERT KC BROWN AB CHIEN KR
Citation: Vtb. Nguyentran et al., HF1-B IS REQUIRED FOR NORMAL PITUITARY DEVELOPMENT AND MARKS THE MATURATION OF CARDIAC VENTRICULAR LINEAGES IN TO PURKINJE-CELLS, Circulation, 96(8), 1997, pp. 1317-1317
MYOSIN LIGHT CHAIN-2V IS ESSENTIAL FOR THE MAINTENANCE OF EMBRYONIC CARDIAC-FUNCTION
Authors: CHEN J KUBALAK SW HICKEY R ROSS J CHIEN KR
Citation: J. Chen et al., MYOSIN LIGHT CHAIN-2V IS ESSENTIAL FOR THE MAINTENANCE OF EMBRYONIC CARDIAC-FUNCTION, Circulation, 96(8), 1997, pp. 1318-1318
RXR HOMODIMER AND RXR PPAR HETERODIMER PATHWAYS NEGATIVELY REGULATE AN ATRIAL MARKER, MLC-2A, AT THE TRANSCRIPTIONAL LEVEL IN VENTRICULAR MUSCLE-CELLS/
Authors: RUIZLOZANO P MERKI EE DOEVENDANS PA ZHOU MD CHIEN KR
Citation: P. Ruizlozano et al., RXR HOMODIMER AND RXR PPAR HETERODIMER PATHWAYS NEGATIVELY REGULATE AN ATRIAL MARKER, MLC-2A, AT THE TRANSCRIPTIONAL LEVEL IN VENTRICULAR MUSCLE-CELLS/, Circulation, 96(8), 1997, pp. 1327-1327
LONG-TERM, STABLE, COTRANSFECTION OF THE NEONATAL MOUSE MYOCARDIUM VIA INTRACARDIAC DELIVERY OF RECOMBINANT ADENOVIRAL CONSTRUCTS
Authors: CHRISTENSEN G WANG YB CHIEN KR
Citation: G. Christensen et al., LONG-TERM, STABLE, COTRANSFECTION OF THE NEONATAL MOUSE MYOCARDIUM VIA INTRACARDIAC DELIVERY OF RECOMBINANT ADENOVIRAL CONSTRUCTS, Circulation, 96(8), 1997, pp. 2700-2700
CARDIAC RESTRICTED GENE TARGETING OF THE RXR-ALPHA GENE REVEALS AN ESSENTIAL, NON-CELL AUTONOMOUS REQUIREMENT OF RETINOID SIGNALS IN VENTRICULAR CHAMBER MORPHOGENESIS
Authors: CHEN J CHIEN KR
Citation: J. Chen et Kr. Chien, CARDIAC RESTRICTED GENE TARGETING OF THE RXR-ALPHA GENE REVEALS AN ESSENTIAL, NON-CELL AUTONOMOUS REQUIREMENT OF RETINOID SIGNALS IN VENTRICULAR CHAMBER MORPHOGENESIS, Circulation, 96(8), 1997, pp. 2805-2805
MOLECULAR DISSECTION OF RAS SIGNAL-TRANSDUCTION PATHWAYS FOR CARDIAC-MUSCLE CELL HYPERTROPHY WITH RECOMBINANT ADENOVIRAL VECTORS - A CENTRAL ROLE FOR STRESS ACTIVATED P38 KINASES
Authors: WANG YB HUANG S SAH VP BROWN JH HAN J CHIEN KR
Citation: Yb. Wang et al., MOLECULAR DISSECTION OF RAS SIGNAL-TRANSDUCTION PATHWAYS FOR CARDIAC-MUSCLE CELL HYPERTROPHY WITH RECOMBINANT ADENOVIRAL VECTORS - A CENTRAL ROLE FOR STRESS ACTIVATED P38 KINASES, Circulation, 96(8), 1997, pp. 3106-3106
EXCITATION-CONTRACTION COUPLING IN VENTRICULAR MYOCYTES ISOLATED FROMFAILING MURINE HEARTS WITH DELETION OF MUSCLE LIM PROTEIN
Authors: YAO A SU Z HUNTER JJ CHIEN KR BARRY WH
Citation: A. Yao et al., EXCITATION-CONTRACTION COUPLING IN VENTRICULAR MYOCYTES ISOLATED FROMFAILING MURINE HEARTS WITH DELETION OF MUSCLE LIM PROTEIN, Circulation, 96(8), 1997, pp. 3192-3192
ANGIOTENSIN-II BLOCKADE FOLLOWED BY GROWTH-HORMONE AFTER MYOCARDIAL-INFARCTION IN RATS
Authors: HONGO M SENTIANIN EM TANAKA N MAO L WONG W MCKIRNAN MD CLARK RG CHIEN KR ROSS J
Citation: M. Hongo et al., ANGIOTENSIN-II BLOCKADE FOLLOWED BY GROWTH-HORMONE AFTER MYOCARDIAL-INFARCTION IN RATS, Circulation, 96(8), 1997, pp. 3518-3518
TANGLED UP IN BLUE - MOLECULAR CARDIOLOGY IN THE POSTMOLECULAR ERA
Authors: PASHMFOROUSH M CHIEN KR
Citation: M. Pashmforoush et Kr. Chien, TANGLED UP IN BLUE - MOLECULAR CARDIOLOGY IN THE POSTMOLECULAR ERA, Circulation, 96(12), 1997, pp. 4126-4130
REPORT OF THE NATIONAL-HEART-LUNG-AND-BLOOD-INSTITUTE SPECIAL EMPHASIS PANEL ON HEART-FAILURE RESEARCH
Authors: COHN JN BRISTOW MR CHIEN KR COLUCCI WS FRAZIER H LEINWAND LA LORELL BH MOSS AJ SONNENBLICK EH WALSH RA MOCKRIN SC REINLIB L
Citation: Jn. Cohn et al., REPORT OF THE NATIONAL-HEART-LUNG-AND-BLOOD-INSTITUTE SPECIAL EMPHASIS PANEL ON HEART-FAILURE RESEARCH, Circulation, 95(4), 1997, pp. 766-770
MOLECULAR CARDIOLOGY IN THE POSTMOLECULAR ERA - TURNING TOWARD COMPLEXITY
Authors: CHIEN KR
Citation: Kr. Chien, MOLECULAR CARDIOLOGY IN THE POSTMOLECULAR ERA - TURNING TOWARD COMPLEXITY, Trends in cardiovascular medicine, 6(1), 1996, pp. 1-3
AN HF-1A HF-1B/MEF-2 COMBINATORIAL ELEMENT CONFERS CARDIAC VENTRICULAR SPECIFICITY AND ESTABLISHES AN ANTERIOR-POSTERIOR GRADIENT OF EXPRESSION/
Authors: ROSS RS NAVANKASATTUSAS S HARVEY RP CHIEN KR
Citation: Rs. Ross et al., AN HF-1A HF-1B/MEF-2 COMBINATORIAL ELEMENT CONFERS CARDIAC VENTRICULAR SPECIFICITY AND ESTABLISHES AN ANTERIOR-POSTERIOR GRADIENT OF EXPRESSION/, Development, 122(6), 1996, pp. 1799-1809
CARDIOTROPHIN-1 DISPLAYS EARLY EXPRESSION IN THE MURINE HEART TUBE AND PROMOTES CARDIAC MYOCYTE SURVIVAL
Authors: SHENG ZL PENNICA D WOOD WI CHIEN KR
Citation: Zl. Sheng et al., CARDIOTROPHIN-1 DISPLAYS EARLY EXPRESSION IN THE MURINE HEART TUBE AND PROMOTES CARDIAC MYOCYTE SURVIVAL, Development, 122(2), 1996, pp. 419-428
EXPRESSION OF CARDIAC-MUSCLE MARKERS IN RAT MYOCYTE CELL-LINES
Authors: ENGELMANN GL WORRELL RA DUFF RA GRUTKOSKI PS CHIEN KR HARVEY RP
Citation: Gl. Engelmann et al., EXPRESSION OF CARDIAC-MUSCLE MARKERS IN RAT MYOCYTE CELL-LINES, Molecular and cellular biochemistry, 157(1-2), 1996, pp. 87-91
STRATEGIES FOR STUDYING CARDIOVASCULAR PHENOTYPES IN GENETICALLY MANIPULATED MICE
Authors: BECKER KD GOTTSHALL KR CHIEN KR
Citation: Kd. Becker et al., STRATEGIES FOR STUDYING CARDIOVASCULAR PHENOTYPES IN GENETICALLY MANIPULATED MICE, Hypertension, 27(3), 1996, pp. 495-501
NEUROFILAMENT-M MESSENGER-RNA IS EXPRESSED IN CONDUCTION SYSTEM MYOCYTES OF THE DEVELOPING AND ADULT-RABBIT HEART
Authors: VITADELLO M VETTORE S LAMAR E CHIEN KR GORZA L
Citation: M. Vitadello et al., NEUROFILAMENT-M MESSENGER-RNA IS EXPRESSED IN CONDUCTION SYSTEM MYOCYTES OF THE DEVELOPING AND ADULT-RABBIT HEART, Journal of Molecular and Cellular Cardiology, 28(9), 1996, pp. 1833-1844
RXR-ALPHA DEFICIENCY CONFERS GENETIC SUSCEPTIBILITY FOR AORTIC SAC, CONOTRUNCAL, ATRIOVENTRICULAR CUSHION, AND VENTRICULAR MUSCLE DEFECTS IN MICE
Authors: GRUBER PJ KUBALAK SW PEXIEDER T SUCOV HM EVANS RM CHIEN KR
Citation: Pj. Gruber et al., RXR-ALPHA DEFICIENCY CONFERS GENETIC SUSCEPTIBILITY FOR AORTIC SAC, CONOTRUNCAL, ATRIOVENTRICULAR CUSHION, AND VENTRICULAR MUSCLE DEFECTS IN MICE, The Journal of clinical investigation, 98(6), 1996, pp. 1332-1343
MOLECULAR MEDICINE IN GENETICALLY-ENGINEERED ANIMALS - SERIES INTRODUCTION
Authors: CHIEN KR
Citation: Kr. Chien, MOLECULAR MEDICINE IN GENETICALLY-ENGINEERED ANIMALS - SERIES INTRODUCTION, The Journal of clinical investigation, 98(11), 1996, pp. 1-1
GENES AND PHYSIOLOGY - MOLECULAR PHYSIOLOGY IN GENETICALLY-ENGINEEREDANIMALS
Authors: CHIEN KR
Citation: Kr. Chien, GENES AND PHYSIOLOGY - MOLECULAR PHYSIOLOGY IN GENETICALLY-ENGINEEREDANIMALS, The Journal of clinical investigation, 98(11), 1996, pp. 19-26
ELEVATED BLOOD-PRESSURE AND ENHANCED MYOCARDIAL-CONTRACTILITY IN MICEWITH SEVERE IGF-1 DEFICIENCY
Authors: LEMBO G ROCKMAN HA HUNTER JJ STEINMETZ H KOCH WJ MA L PRINZ MP ROSS J CHIEN KR POWELLBRAXTON L
Citation: G. Lembo et al., ELEVATED BLOOD-PRESSURE AND ENHANCED MYOCARDIAL-CONTRACTILITY IN MICEWITH SEVERE IGF-1 DEFICIENCY, The Journal of clinical investigation, 98(11), 1996, pp. 2648-2655
GENES AND PHYSIOLOGY - MOLECULAR PHYSIOLOGY IN GENETICALLY-ENGINEEREDANIMALS
Authors: CHIEN KR
Citation: Kr. Chien, GENES AND PHYSIOLOGY - MOLECULAR PHYSIOLOGY IN GENETICALLY-ENGINEEREDANIMALS, The Journal of clinical investigation, 97(4), 1996, pp. 901-909
MOLECULAR MEDICINE IN GENETICALLY-ENGINEERED ANIMALS - SERIES INTRODUCTION
Authors: CHIEN KR
Citation: Kr. Chien, MOLECULAR MEDICINE IN GENETICALLY-ENGINEERED ANIMALS - SERIES INTRODUCTION, The Journal of clinical investigation, 97(1), 1996, pp. 2-2
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