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Results: 1-25 | 26-35
Results: 1-25/35
THE DESIGN, SYNTHESIS, AND INITIAL EVALUATION OF BENZOPHENONE-CONTAINING PEPTIDES AS POTENTIAL PHOTOAFFINITY LABELS OF OLIGOSACCHARYLTRANSFERASE
Authors: XU T KHANNA H COWARD JK
Citation: T. Xu et al., THE DESIGN, SYNTHESIS, AND INITIAL EVALUATION OF BENZOPHENONE-CONTAINING PEPTIDES AS POTENTIAL PHOTOAFFINITY LABELS OF OLIGOSACCHARYLTRANSFERASE, Bioorganic & medicinal chemistry, 6(10), 1998, pp. 1821-1834
A CELL-CYCLE-REGULATED ADENINE DNA METHYLTRANSFERASE FROM CAULOBACTER-CRESCENTUS PROCESSIVELY METHYLATES GANTC SITES ON HEMIMETHYLATED DNA
Authors: BERDIS AJ LEE I COWARD JK STEPHENS C WRIGHT R SHAPIRO L BENKOVIC SJ
Citation: Aj. Berdis et al., A CELL-CYCLE-REGULATED ADENINE DNA METHYLTRANSFERASE FROM CAULOBACTER-CRESCENTUS PROCESSIVELY METHYLATES GANTC SITES ON HEMIMETHYLATED DNA, Proceedings of the National Academy of Sciences of the United Statesof America, 95(6), 1998, pp. 2874-2879
INVESTIGATIONS ON NEW STRATEGIES FOR THE FACILE SYNTHESIS OF POLYFUNCTIONALIZED PHOSPHINATES - PHOSPHINOPEPTIDE ANALOGS OF GLUTATHIONYLSPERMIDINE
Authors: CHEN SJ COWARD JK
Citation: Sj. Chen et Jk. Coward, INVESTIGATIONS ON NEW STRATEGIES FOR THE FACILE SYNTHESIS OF POLYFUNCTIONALIZED PHOSPHINATES - PHOSPHINOPEPTIDE ANALOGS OF GLUTATHIONYLSPERMIDINE, Journal of organic chemistry, 63(3), 1998, pp. 502-509
SYNTHESIS AND EVALUATION OF TRIPEPTIDES CONTAINING ASPARAGINE ANALOGSAS POTENTIAL SUBSTRATES OR INHIBITORS OF OLIGOSACCHARYLTRANSFERASE
Authors: XU T WERNER RM LEE KC FETTINGER JC DAVIS JT COWARD JK
Citation: T. Xu et al., SYNTHESIS AND EVALUATION OF TRIPEPTIDES CONTAINING ASPARAGINE ANALOGSAS POTENTIAL SUBSTRATES OR INHIBITORS OF OLIGOSACCHARYLTRANSFERASE, Journal of organic chemistry, 63(14), 1998, pp. 4767-4778
MECHANISM-BASED INHIBITION OF HUMAN FOLYLPOLYGLUTAMATE SYNTHETASE - DESIGN, SYNTHESIS, AND BIOCHEMICAL-CHARACTERIZATION OF A PHOSPHAPEPTIDEMIMIC OF THE TETRAHEDRAL INTERMEDIATE
Authors: TSUKAMOTO T HAILE WH MCGUIRE JJ COWARD JK
Citation: T. Tsukamoto et al., MECHANISM-BASED INHIBITION OF HUMAN FOLYLPOLYGLUTAMATE SYNTHETASE - DESIGN, SYNTHESIS, AND BIOCHEMICAL-CHARACTERIZATION OF A PHOSPHAPEPTIDEMIMIC OF THE TETRAHEDRAL INTERMEDIATE, Archives of biochemistry and biophysics (Print), 355(1), 1998, pp. 109-118
ALDEHYDE AND PHOSPHINATE ANALOGS OF GLUTATHIONE AND GLUTATHIONYLSPERMIDINE - POTENT, SELECTIVE BINDING INHIBITORS OF THE ESCHERICHIA-COLI BIFUNCTIONAL GLUTATHIONYLSPERMIDINE SYNTHETASE AMIDASE/
Authors: LIN CH CHEN SJ KWON DS COWARD JK WALSH CT
Citation: Ch. Lin et al., ALDEHYDE AND PHOSPHINATE ANALOGS OF GLUTATHIONE AND GLUTATHIONYLSPERMIDINE - POTENT, SELECTIVE BINDING INHIBITORS OF THE ESCHERICHIA-COLI BIFUNCTIONAL GLUTATHIONYLSPERMIDINE SYNTHETASE AMIDASE/, Chemistry & biology, 4(11), 1997, pp. 859-866
NOVEL INHIBITORS OF TRYPANOTHIONE BIOSYNTHESIS - SYNTHESIS AND EVALUATION OF A PHOSPHINATE ANALOG OF GLUTATHIONYL SPERMIDINE (GSP), A POTENT, SLOW-BINDING INHIBITOR OF GSP SYNTHETASE
Authors: CHEN SJ LIN CH WALSH CT COWARD JK
Citation: Sj. Chen et al., NOVEL INHIBITORS OF TRYPANOTHIONE BIOSYNTHESIS - SYNTHESIS AND EVALUATION OF A PHOSPHINATE ANALOG OF GLUTATHIONYL SPERMIDINE (GSP), A POTENT, SLOW-BINDING INHIBITOR OF GSP SYNTHETASE, Bioorganic & medicinal chemistry letters, 7(5), 1997, pp. 505-510
NOVEL INHIBITORS OF TRYPANOTHIONE BIOSYNTHESIS - SYNTHESIS AND EVALUATION OF A PHOSPHINATE ANALOG OF GLUTATHIONYL SPERMIDINE (GSP), A POTENT, SLOW-BINDING INHIBITOR OF GSP SYNTHETASE (VOL 7, PG 505, 1997)
Authors: CHEN S LIN CH WALSH CT COWARD JK
Citation: S. Chen et al., NOVEL INHIBITORS OF TRYPANOTHIONE BIOSYNTHESIS - SYNTHESIS AND EVALUATION OF A PHOSPHINATE ANALOG OF GLUTATHIONYL SPERMIDINE (GSP), A POTENT, SLOW-BINDING INHIBITOR OF GSP SYNTHETASE (VOL 7, PG 505, 1997), Bioorganic & medicinal chemistry letters, 7(19), 1997, pp. 2557-2557
DESIGN, SYNTHESIS, AND BIOCHEMICAL EVALUATION OF PHOSPHONATE AND PHOSPHONAMIDATE ANALOGS OF GLUTATHIONYLSPERMIDINE AS INHIBITORS OF GLUTATHIONYLSPERMIDINE SYNTHETASE AMIDASE FROM ESCHERICHIA-COLI/
Authors: CHEN SJ LIN CH KWON DS WALSH CT COWARD JK
Citation: Sj. Chen et al., DESIGN, SYNTHESIS, AND BIOCHEMICAL EVALUATION OF PHOSPHONATE AND PHOSPHONAMIDATE ANALOGS OF GLUTATHIONYLSPERMIDINE AS INHIBITORS OF GLUTATHIONYLSPERMIDINE SYNTHETASE AMIDASE FROM ESCHERICHIA-COLI/, Journal of medicinal chemistry, 40(23), 1997, pp. 3842-3850
DISSECTION OF GLUTATHIONYLSPERMIDINE SYNTHETASE AMIDASE FROM ESCHERICHIA-COLI INTO AUTONOMOUSLY FOLDING AND FUNCTIONAL SYNTHETASE AND AMIDASE DOMAINS/
Authors: KWON DS LIN CH CHEN SJ COWARD JK WALSH CT BOLLINGER JM
Citation: Ds. Kwon et al., DISSECTION OF GLUTATHIONYLSPERMIDINE SYNTHETASE AMIDASE FROM ESCHERICHIA-COLI INTO AUTONOMOUSLY FOLDING AND FUNCTIONAL SYNTHETASE AND AMIDASE DOMAINS/, The Journal of biological chemistry, 272(4), 1997, pp. 2429-2436
C-13-LABELED AND N-15-LABELED PEPTIDE-SUBSTRATES AS MECHANISTIC PROBES OF OLIGOSACCHARYLTRANSFERASE
Authors: XU T COWARD JK
Citation: T. Xu et Jk. Coward, C-13-LABELED AND N-15-LABELED PEPTIDE-SUBSTRATES AS MECHANISTIC PROBES OF OLIGOSACCHARYLTRANSFERASE, Biochemistry, 36(48), 1997, pp. 14683-14689
EXPLOITATION OF FOLATE AND ANTIFOLATE POLYGLUTAMYLATION TO ACHIEVE SELECTIVE ANTICANCER CHEMOTHERAPY
Authors: MCGUIRE JJ TSUKAMOTO T HART BP COWARD JK KALMAN TI GALIVAN J
Citation: Jj. Mcguire et al., EXPLOITATION OF FOLATE AND ANTIFOLATE POLYGLUTAMYLATION TO ACHIEVE SELECTIVE ANTICANCER CHEMOTHERAPY, Investigational new drugs, 14(3), 1996, pp. 317-323
A GENERAL-METHOD FOR THE SYNTHESIS OF N-PROTECTED ALPHA-AMINOALKYLPHOSPHINIC ACIDS
Authors: CHEN SJ COWARD JK
Citation: Sj. Chen et Jk. Coward, A GENERAL-METHOD FOR THE SYNTHESIS OF N-PROTECTED ALPHA-AMINOALKYLPHOSPHINIC ACIDS, Tetrahedron letters, 37(25), 1996, pp. 4335-4338
FACILE SYNTHESIS OF DL-4,4-DIFLUOROORNITHINE, DL-4,4-DIFLUOROGLUTAMINE, AND GAMMA-DL-4,4-DIFLUOROGLUTAMYL-CONTAINING PEPTIDES - REGIOSPECIFIC ADDITION OF NUCLEOPHILES TO N-CBZ-DI-TERT-BUTYL-DL-4,4-DIFLUOROGLUTAMATE
Authors: TSUKAMOTO T COWARD JK
Citation: T. Tsukamoto et Jk. Coward, FACILE SYNTHESIS OF DL-4,4-DIFLUOROORNITHINE, DL-4,4-DIFLUOROGLUTAMINE, AND GAMMA-DL-4,4-DIFLUOROGLUTAMYL-CONTAINING PEPTIDES - REGIOSPECIFIC ADDITION OF NUCLEOPHILES TO N-CBZ-DI-TERT-BUTYL-DL-4,4-DIFLUOROGLUTAMATE, Journal of organic chemistry, 61(7), 1996, pp. 2497-2500
SYNTHESIS AND BIOLOGICAL-ACTIVITY OF FOLIC-ACID AND METHOTREXATE ANALOGS CONTAINING L-THREO-(2S,4S)-4-FLUOROGLUTAMIC ACID AND DL-3,3-DIFLUOROGLUTAMIC ACID (VOL 39, PG 59, 1996)
Authors: HART BP HAILE WH LICATO NJ BOLANOWSKA WE MCGUIRE JJ COWARD JK
Citation: Bp. Hart et al., SYNTHESIS AND BIOLOGICAL-ACTIVITY OF FOLIC-ACID AND METHOTREXATE ANALOGS CONTAINING L-THREO-(2S,4S)-4-FLUOROGLUTAMIC ACID AND DL-3,3-DIFLUOROGLUTAMIC ACID (VOL 39, PG 59, 1996), Journal of medicinal chemistry, 39(20), 1996, pp. 4134-4134
SYNTHESIS AND BIOLOGICAL EVALUATION OF DL-4,4-DIFLUOROGLUTAMIC ACID AND DL-GAMMA,GAMMA-DIFLUOROMETHOTREXATE (VOL 39, PG 68, 1996)
Authors: TSUKAMOTO T KITAZUME T MCGUIRE JJ COWARD JK
Citation: T. Tsukamoto et al., SYNTHESIS AND BIOLOGICAL EVALUATION OF DL-4,4-DIFLUOROGLUTAMIC ACID AND DL-GAMMA,GAMMA-DIFLUOROMETHOTREXATE (VOL 39, PG 68, 1996), Journal of medicinal chemistry, 39(20), 1996, pp. 4134-4134
SYNTHESIS AND BIOLOGICAL EVALUATION OF 4-DEOXY-10-METHYLPTEROYL)-DL-4,4-DIFLUOROORNITHINE
Authors: TSUKAMOTO T HAILE WH MCGUIRE JJ COWARD JK
Citation: T. Tsukamoto et al., SYNTHESIS AND BIOLOGICAL EVALUATION OF 4-DEOXY-10-METHYLPTEROYL)-DL-4,4-DIFLUOROORNITHINE, Journal of medicinal chemistry, 39(13), 1996, pp. 2536-2540
SYNTHESIS AND BIOLOGICAL-ACTIVITY OF FOLIC-ACID AND METHOTREXATE ANALOGS CONTAINING L-THREO-(2S,4S)-4-FLUOROGLUTAMIC ACID AND DL-3,3-DIFLUOROGLUTAMIC ACID
Authors: HART BP HAILE WH LICATO NJ BOLANOWSKA WE MCGUIRE JJ COWARD JK
Citation: Bp. Hart et al., SYNTHESIS AND BIOLOGICAL-ACTIVITY OF FOLIC-ACID AND METHOTREXATE ANALOGS CONTAINING L-THREO-(2S,4S)-4-FLUOROGLUTAMIC ACID AND DL-3,3-DIFLUOROGLUTAMIC ACID, Journal of medicinal chemistry, 39(1), 1996, pp. 56-65
SYNTHESIS AND BIOLOGICAL EVALUATION OF DL-4,4-DIFLUOROGLUTAMIC ACID AND DL-GAMMA,GAMMA-DIFLUOROMETHOTREXATE
Authors: TSUKAMOTO T KITAZUME T MCGUIRE JJ COWARD JK
Citation: T. Tsukamoto et al., SYNTHESIS AND BIOLOGICAL EVALUATION OF DL-4,4-DIFLUOROGLUTAMIC ACID AND DL-GAMMA,GAMMA-DIFLUOROMETHOTREXATE, Journal of medicinal chemistry, 39(1), 1996, pp. 66-72
KINETIC-STUDIES OF OLIGOSACCHARYLTRANSFERASE-CATALYZED GLYCOSYLATION - STRUCTURAL MODIFICATION OF THE CARBOHYDRATE DONOR AND PEPTIDE ACCEPTOR SUBSTRATES
Authors: COWARD JK GIBBS BS LIU YL FANG X
Citation: Jk. Coward et al., KINETIC-STUDIES OF OLIGOSACCHARYLTRANSFERASE-CATALYZED GLYCOSYLATION - STRUCTURAL MODIFICATION OF THE CARBOHYDRATE DONOR AND PEPTIDE ACCEPTOR SUBSTRATES, Biochemistry, 35(28), 1996, pp. 86-86
BIOLOGICAL PROPERTIES OF FLUOROGLUTAMATE-CONTAINING ANALOGS OF FOLATES AND METHOTREXATE WITH ALTERED CAPACITIES TO FORM POLY (GAMMA-GLUTAMATE) METABOLITES
Authors: MCGUIRE JJ HART BP HAILE WH MAGEE KJ RHEE M BOLANOWSKA WE RUSSELL C GALIVAN J PAUL B COWARD JK
Citation: Jj. Mcguire et al., BIOLOGICAL PROPERTIES OF FLUOROGLUTAMATE-CONTAINING ANALOGS OF FOLATES AND METHOTREXATE WITH ALTERED CAPACITIES TO FORM POLY (GAMMA-GLUTAMATE) METABOLITES, Biochemical pharmacology, 52(8), 1996, pp. 1295-1303
USE OF AMINOPROPYLTRANSFERASE INHIBITORS AND OF NONMETABOLIZABLE ANALOGS TO STUDY POLYAMINE REGULATION AND FUNCTION
Authors: PEGG AE POULIN R COWARD JK
Citation: Ae. Pegg et al., USE OF AMINOPROPYLTRANSFERASE INHIBITORS AND OF NONMETABOLIZABLE ANALOGS TO STUDY POLYAMINE REGULATION AND FUNCTION, International journal of biochemistry & cell biology, 27(5), 1995, pp. 425-442
SYNTHESIS AND EVALUATION OF SYNTHETIC ANALOGS OF DOLICHYL-P-P-CHITOBIOSE AS OLIGOSACCHARYLTRANSFERASE SUBSTRATES
Authors: FANG XG GIBBS BS COWARD JK
Citation: Xg. Fang et al., SYNTHESIS AND EVALUATION OF SYNTHETIC ANALOGS OF DOLICHYL-P-P-CHITOBIOSE AS OLIGOSACCHARYLTRANSFERASE SUBSTRATES, Bioorganic & medicinal chemistry letters, 5(22), 1995, pp. 2701-2706
POSITION-DEPENDENT ENHANCEMENT OR TERMINATION OF FOLATE POLYGLUTAMYLATION BY DL-3,3-DIFLUOROGLUTAMIC ACID
Authors: COWARD JK HART BP MCGUIRE JJ HAILE WH
Citation: Jk. Coward et al., POSITION-DEPENDENT ENHANCEMENT OR TERMINATION OF FOLATE POLYGLUTAMYLATION BY DL-3,3-DIFLUOROGLUTAMIC ACID, The FASEB journal, 9(6), 1995, pp. 1296-1296
RECOGNITION OF PEPTIDE-SUBSTRATES BY YEAST OLIGOSACCHARYLTRANSFERASE
Authors: GIBBS BS LIU YL COWARD JK
Citation: Bs. Gibbs et al., RECOGNITION OF PEPTIDE-SUBSTRATES BY YEAST OLIGOSACCHARYLTRANSFERASE, The FASEB journal, 9(6), 1995, pp. 1360-1360
Risultati: 1-25 | 26-35