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Results: 1-25 | 26-28
Results: 1-25/28
Comparison of five retrovirus vectors containing the human IL-2 receptor gamma chain gene for their ability to restore T and B lymphocytes in the X-linked severe combined immunodeficiency mouse model
Authors: Mendoza, GJA Seidel, NE Otsu, M Anderson, SM Simon-Stoos, K Herrera, A Hoogstraten-Miller, S Malech, HL Candotti, F Puck, JM Bodine, DM
Citation: Gja. Mendoza et al., Comparison of five retrovirus vectors containing the human IL-2 receptor gamma chain gene for their ability to restore T and B lymphocytes in the X-linked severe combined immunodeficiency mouse model, MOL THER, 3(4), 2001, pp. 565-573
Unexpected effects of FERM domain mutations on catalytic activity of Jak3:Structural implication for Janus kinases
Authors: Zhou, YJ Chen, M Cusack, NA Kimmel, LH Magnuson, KS Boyd, JG Lin, W Roberts, JL Lengi, A Buckley, RH Geahlen, RL Candotti, F Gadina, M Changelian, PS O'Shea, JJ
Citation: Yj. Zhou et al., Unexpected effects of FERM domain mutations on catalytic activity of Jak3:Structural implication for Janus kinases, MOL CELL, 8(5), 2001, pp. 959-969
Expansion of hepatic and hematopoietic stem cells utilizing mouse embryonic liver explants
Authors: Monga, SPS Tang, Y Candotti, F Rashid, A Wildner, O Mishra, B Iqbal, S Mishra, L
Citation: Sps. Monga et al., Expansion of hepatic and hematopoietic stem cells utilizing mouse embryonic liver explants, CELL TRANSP, 10(1), 2001, pp. 81-89
Somatic mosaicism in Wiskott-Aldrich syndrome suggests in vivo reversion by a DNA slippage mechanism
Authors: Wada, T Schurman, SH Otsu, M Garabedian, EK Ochs, HD Nelson, DL Candotti, F
Citation: T. Wada et al., Somatic mosaicism in Wiskott-Aldrich syndrome suggests in vivo reversion by a DNA slippage mechanism, P NAS US, 98(15), 2001, pp. 8697-8702
Lack of dominant-negative effects of a truncated gamma c on retroviral-mediated gene correction of immunodeficient mice
Authors: Otsu, M Sugamura, K Candotti, F
Citation: M. Otsu et al., Lack of dominant-negative effects of a truncated gamma c on retroviral-mediated gene correction of immunodeficient mice, BLOOD, 97(6), 2001, pp. 1618-1624
Biosynthetic ganciclovir triphosphate: Its isolation and characterization from ganciclovir-treated herpes simplex thymidine kinase-transduced murine cells
Authors: Agbaria, R Candotti, F Kelley, JA Hao, Z Johns, DG Cooney, DA Blaese, RM Ford, H
Citation: R. Agbaria et al., Biosynthetic ganciclovir triphosphate: Its isolation and characterization from ganciclovir-treated herpes simplex thymidine kinase-transduced murine cells, BIOC BIOP R, 289(2), 2001, pp. 525-530
Gene therapy for inherited immunodeficiencies
Authors: Candotti, F Blaese, RM
Citation: F. Candotti et Rm. Blaese, Gene therapy for inherited immunodeficiencies, THERAPEUTIC IMMUNOLOGY, SECOND EDITION, 2001, pp. 580-596
Lymphoid development and function in X-linked severe combined immunodeficiency mice after stem cell gene therapy
Authors: Otsu, M Anderson, SM Bodine, DM Puck, JM O'Shea, JJ Candotti, F
Citation: M. Otsu et al., Lymphoid development and function in X-linked severe combined immunodeficiency mice after stem cell gene therapy, MOL THER, 1(2), 2000, pp. 145-153
Molecular modeling of the Jak3 kinase domains and structural basis for severe combined immunodeficiency
Authors: Vihinen, M Villa, A Mella, P Schumacher, RF Savoldi, G O'Shea, JJ Candotti, F Notarangelo, LD
Citation: M. Vihinen et al., Molecular modeling of the Jak3 kinase domains and structural basis for severe combined immunodeficiency, CLIN IMMUNO, 96(2), 2000, pp. 108-118
Development of autologous T lymphocytes in two males with X-linked severe combined immune deficiency: Molecular and cellular characterization
Authors: Mella, P Imberti, L Brugnoni, D Pirovano, S Candotti, F Mazzolari, E Bettinardi, A Fiorini, M De Mattia, D Martire, B Plebani, A Notarangelo, LD Giliani, S
Citation: P. Mella et al., Development of autologous T lymphocytes in two males with X-linked severe combined immune deficiency: Molecular and cellular characterization, CLIN IMMUNO, 95(1), 2000, pp. 39-50
In vivo competitive studies between normal and common gamma chain-defective bone marrow cells: Implications for gene therapy
Authors: Otsu, M Sugamura, K Candotti, F
Citation: M. Otsu et al., In vivo competitive studies between normal and common gamma chain-defective bone marrow cells: Implications for gene therapy, HUM GENE TH, 11(14), 2000, pp. 2051-2056
Efficient gene transfer to human peripheral blood monocyte-derived dendritic cells using human immunodeficiency virus type 1-based lentiviral vectors
Authors: Chinnasamy, N Chinnasamy, D Toso, JF Lapointe, R Candotti, F Morgan, RA Hwu, P
Citation: N. Chinnasamy et al., Efficient gene transfer to human peripheral blood monocyte-derived dendritic cells using human immunodeficiency virus type 1-based lentiviral vectors, HUM GENE TH, 11(13), 2000, pp. 1901-1909
Use of a herpes thymidine kinase/neomycin phosphotransferase chimeric genefor metabolic suicide gene transfer
Authors: Candotti, F Agbaria, R Mullen, CA Touraine, R Balzarini, J Johns, DG Blaese, RM
Citation: F. Candotti et al., Use of a herpes thymidine kinase/neomycin phosphotransferase chimeric genefor metabolic suicide gene transfer, CANC GENE T, 7(4), 2000, pp. 574-580
JAK3-deficient severe combined immunodeficiency
Authors: Notarangelo, LD Candotti, F
Citation: Ld. Notarangelo et F. Candotti, JAK3-deficient severe combined immunodeficiency, IMMUNOL ALL, 20(1), 2000, pp. 97
Complete genomic organization of the human JAK3 gene and mutation analysisin severe combined immunodeficiency by single-strand conformation polymorphism
Authors: Schumacher, RF Mella, P Badolato, R Fiorini, M Savoldi, G Giliani, S Villa, A Candotti, F Tampalini, A O'Shea, JJ Notarangelo, LD
Citation: Rf. Schumacher et al., Complete genomic organization of the human JAK3 gene and mutation analysisin severe combined immunodeficiency by single-strand conformation polymorphism, HUM GENET, 106(1), 2000, pp. 73-79
Complex effects of naturally occurring mutations in the JAK3 pseudokinase domain: Evidence for interactions between the kinase and pseudokinase domains
Authors: Chen, M Cheng, A Candotti, F Zhou, YJ Hymel, A Fasth, A Notarangelo, LD O'Shea, JJ
Citation: M. Chen et al., Complex effects of naturally occurring mutations in the JAK3 pseudokinase domain: Evidence for interactions between the kinase and pseudokinase domains, MOL CELL B, 20(3), 2000, pp. 947-956
Hierarchy of protein tyrosine kinases in interleukin-2 (IL2) signaling: Activation of Syk depends on Jak3; However, neither Syk nor Lck is required for IL-2-mediated STAT activation
Authors: Zhou, YJ Magnuson, KS Cheng, TP Gadina, M Frucht, DM Galon, J Candotti, F Geahlen, RL Changelian, PS O'Shea, JJ
Citation: Yj. Zhou et al., Hierarchy of protein tyrosine kinases in interleukin-2 (IL2) signaling: Activation of Syk depends on Jak3; However, neither Syk nor Lck is required for IL-2-mediated STAT activation, MOL CELL B, 20(12), 2000, pp. 4371-4380
Combined immunodeficiencies due to defects in signal transduction: Defectsof the gamma(c)-JAK3 signaling pathway as a model
Authors: Notarangelo, LD Giliani, S Mella, P Schumacher, RF Mazza, C Savoldi, G Rodriguez-Perez, C Badolato, R Mazzolari, E Porta, F Candotti, F Ugazio, AG
Citation: Ld. Notarangelo et al., Combined immunodeficiencies due to defects in signal transduction: Defectsof the gamma(c)-JAK3 signaling pathway as a model, IMMUNOBIOL, 202(2), 2000, pp. 106-119
Of genes and phenotypes: the immunological and molecular spectrum of combined immune deficiency. Defects of the gamma(c)-JAK3 signaling pathway as a model
Authors: Notarangelo, LD Giliani, S Mazza, C Mella, P Savoldi, G Rodriguez-Perez, C Mazzolari, E Fiorini, M Duse, M Plebani, A Ugazio, AG Vihinen, M Candotti, F Schumacher, RF
Citation: Ld. Notarangelo et al., Of genes and phenotypes: the immunological and molecular spectrum of combined immune deficiency. Defects of the gamma(c)-JAK3 signaling pathway as a model, IMMUNOL REV, 178, 2000, pp. 39-48
The potential for therapy of immune disorders with gene therapy
Authors: Candotti, F
Citation: F. Candotti, The potential for therapy of immune disorders with gene therapy, PED CLIN NA, 47(6), 2000, pp. 1389-1407
Lentiviral-mediated gene transfer into human lymphocytes: role of HIV-1 accessory proteins
Authors: Chinnasamy, D Chinnasamy, N Enriquez, MJ Otsu, M Morgan, RA Candotti, F
Citation: D. Chinnasamy et al., Lentiviral-mediated gene transfer into human lymphocytes: role of HIV-1 accessory proteins, BLOOD, 96(4), 2000, pp. 1309-1316
Retrovirus-mediated WASP gene transfer corrects defective actin polymerization in B cell lines from Wiskott-Aldrich syndrome patients carrying 'null'mutations
Authors: Candotti, F Facchetti, F Blanzuoli, L Stewart, DM Nelson, DL Blaese, RM
Citation: F. Candotti et al., Retrovirus-mediated WASP gene transfer corrects defective actin polymerization in B cell lines from Wiskott-Aldrich syndrome patients carrying 'null'mutations, GENE THER, 6(6), 1999, pp. 1170-1174
Autosomal SCID caused by a point mutation in the N-terminus of Jak3: mapping of the Jak3-receptor interaction domain
Authors: Cacalano, NA Migone, TS Bazan, F Hanson, EP Chen, M Candotti, F O'Shea, JJ Johnston, JA
Citation: Na. Cacalano et al., Autosomal SCID caused by a point mutation in the N-terminus of Jak3: mapping of the Jak3-receptor interaction domain, EMBO J, 18(6), 1999, pp. 1549-1558
Prenatal diagnosis of JAK3 deficient SCID
Authors: Schumacher, RF Mella, P Lalatta, F Fiorini, M Giliani, S Villa, A Candotti, F Notarangelo, LD
Citation: Rf. Schumacher et al., Prenatal diagnosis of JAK3 deficient SCID, PRENAT DIAG, 19(7), 1999, pp. 653-656
Prenatal molecular diagnosis of Wiskott-Aldrich syndrome by direct mutation analysis
Authors: Giliani, S Fiorini, J Mella, P Candotti, F Schumacher, RF Wengler, GS Lalatta, F Fasth, A Badolato, R Ugazio, AG Albertini, A Notarangelo, LD
Citation: S. Giliani et al., Prenatal molecular diagnosis of Wiskott-Aldrich syndrome by direct mutation analysis, PRENAT DIAG, 19(1), 1999, pp. 36-40
Risultati: 1-25 | 26-28