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Results: 1-23 |
Results: 23
Structural, signalling and regulatory properties of the group I metabotropic glutamate receptors: prototypic family C G-protein-coupled receptors
Authors: Hermans, E Challiss, RAJ
Citation: E. Hermans et Raj. Challiss, Structural, signalling and regulatory properties of the group I metabotropic glutamate receptors: prototypic family C G-protein-coupled receptors, BIOCHEM J, 359, 2001, pp. 465-484
Single-cell imaging of graded Ins(1,4,5)P-3 production following G-protein-coupled-receptor activation
Authors: Nash, MS Young, KW Willars, GB Challiss, RAJ Nahorski, SR
Citation: Ms. Nash et al., Single-cell imaging of graded Ins(1,4,5)P-3 production following G-protein-coupled-receptor activation, BIOCHEM J, 356, 2001, pp. 137-142
Cell type-specific differences in the coupling of recombinant mGlu1 alpha receptors to endogenous G protein sub-populations
Authors: Selkirk, JV Price, GW Nahorski, SR Challiss, RAJ
Citation: Jv. Selkirk et al., Cell type-specific differences in the coupling of recombinant mGlu1 alpha receptors to endogenous G protein sub-populations, NEUROPHARM, 40(5), 2001, pp. 645-656
Intracellular signalling - Receptor-specific messenger oscillations
Authors: Nash, MS Young, KW Challiss, RAJ Nahorski, SR
Citation: Ms. Nash et al., Intracellular signalling - Receptor-specific messenger oscillations, NATURE, 413(6854), 2001, pp. 381-382
G protein-coupled receptor kinases 3 and 6 use different pathways to desensitize the endogenous M-3 muscarinic acetylcholine receptor in human SH-SY5Y cells
Authors: Willets, JM Challiss, RAJ Kelly, E Nahorski, SR
Citation: Jm. Willets et al., G protein-coupled receptor kinases 3 and 6 use different pathways to desensitize the endogenous M-3 muscarinic acetylcholine receptor in human SH-SY5Y cells, MOLEC PHARM, 60(2), 2001, pp. 321-330
Enhanced inducible mGlu1 alpha receptor expression in Chinese hamster ovary cells
Authors: Nash, MS Selkirk, JV Gaymer, CE Challiss, RAJ Nahorski, SR
Citation: Ms. Nash et al., Enhanced inducible mGlu1 alpha receptor expression in Chinese hamster ovary cells, J NEUROCHEM, 77(6), 2001, pp. 1664-1667
Reassessment of the Ca2+ sensing property of a type I metabotropic glutamate receptor by simultaneous measurement of inositol 1,4,5-trisphosphate andCa2+ in single cells
Authors: Nash, MS Saunders, R Young, KW Challiss, RAJ Nahorski, SR
Citation: Ms. Nash et al., Reassessment of the Ca2+ sensing property of a type I metabotropic glutamate receptor by simultaneous measurement of inositol 1,4,5-trisphosphate andCa2+ in single cells, J BIOL CHEM, 276(22), 2001, pp. 19286-19293
G(q/11) and G(i/o) activation profiles in CHO cells expressing human muscarinic acetylcholine receptors: dependence on agonist as well as receptor-subtype
Authors: Akam, EC Challiss, RAJ Nahorski, SR
Citation: Ec. Akam et al., G(q/11) and G(i/o) activation profiles in CHO cells expressing human muscarinic acetylcholine receptors: dependence on agonist as well as receptor-subtype, BR J PHARM, 132(4), 2001, pp. 950-958
Spirophostins: Conformationally restricted analogues of adenophostin A
Authors: de Kort, M Regenbogen, AD Valentijn, ARPM Challiss, RAJ Iwata, Y Miyamoto, S van der Marcel, GA van Boom, JH
Citation: M. De Kort et al., Spirophostins: Conformationally restricted analogues of adenophostin A, CHEM-EUR J, 6(15), 2000, pp. 2696-2704
Synthesis and biological evaluation of cyclophostin: A 5 ',6 ''-tethered analog of adenophostin A
Authors: de Kort, M Regenbogen, AD Overkleeft, HS Challiss, RAJ Iwata, Y Miyamoto, S van der Marel, GA van Boom, JH
Citation: M. De Kort et al., Synthesis and biological evaluation of cyclophostin: A 5 ',6 ''-tethered analog of adenophostin A, TETRAHEDRON, 56(32), 2000, pp. 5915-5928
Complex involvement of pertussis toxin-sensitive G proteins in the regulation of type 1 alpha metabotropic glutamate receptor signaling in baby hamster kidney cells
Authors: Hermans, E Saunders, R Selkirk, JV Mistry, R Nahorski, SR Challiss, RAJ
Citation: E. Hermans et al., Complex involvement of pertussis toxin-sensitive G proteins in the regulation of type 1 alpha metabotropic glutamate receptor signaling in baby hamster kidney cells, MOLEC PHARM, 58(2), 2000, pp. 352-360
Lysophosphatidic acid-induced Ca2+ mobilization requires intracellular sphingosine 1-phosphate production - Potential involvement of endogenous Edg-4receptors
Authors: Young, KW Bootman, MD Channing, DR Lipp, P Maycox, PR Meakin, J Challiss, RAJ Nahorski, SR
Citation: Kw. Young et al., Lysophosphatidic acid-induced Ca2+ mobilization requires intracellular sphingosine 1-phosphate production - Potential involvement of endogenous Edg-4receptors, J BIOL CHEM, 275(49), 2000, pp. 38532-38539
Heterologous mammalian expression systems for investigating the propertiesof metabotropic glutamate receptors
Authors: Hermans, E Nahorski, SR Challiss, RAJ
Citation: E. Hermans et al., Heterologous mammalian expression systems for investigating the propertiesof metabotropic glutamate receptors, BIOCH SOC T, 27(2), 1999, pp. 164-170
Lysophosphatidic acid-mediated Ca2+ mobilization in human SH-SY5Y neuroblastoma cells is independent of phosphoinositide signalling, but dependent onsphingosine kinase activation
Authors: Young, KW Challiss, RAJ Nahorski, SR Mackrill, JJ
Citation: Kw. Young et al., Lysophosphatidic acid-mediated Ca2+ mobilization in human SH-SY5Y neuroblastoma cells is independent of phosphoinositide signalling, but dependent onsphingosine kinase activation, BIOCHEM J, 343, 1999, pp. 45-52
Enhanced purinoceptor-mediated Ca2+ signalling in L-fibroblasts overexpressing type 1 inositol 1,4,5-trisphosphate receptors
Authors: Davis, RJ Challiss, RAJ Nahorski, SR
Citation: Rj. Davis et al., Enhanced purinoceptor-mediated Ca2+ signalling in L-fibroblasts overexpressing type 1 inositol 1,4,5-trisphosphate receptors, BIOCHEM J, 341, 1999, pp. 813-820
Regulation of extracellular-signal regulated kinase and c-Jun N-terminal kinase by G-protein-linked muscarinic acetylcholine receptors
Authors: Wylie, PG Challiss, RAJ Blank, JL
Citation: Pg. Wylie et al., Regulation of extracellular-signal regulated kinase and c-Jun N-terminal kinase by G-protein-linked muscarinic acetylcholine receptors, BIOCHEM J, 338, 1999, pp. 619-628
Agonist-induced desensitization and phosphorylation of m1-muscarinic receptors
Authors: Waugh, MG Challiss, RAJ Berstein, G Nahorski, SR Tobin, AB
Citation: Mg. Waugh et al., Agonist-induced desensitization and phosphorylation of m1-muscarinic receptors, BIOCHEM J, 338, 1999, pp. 175-183
Inhibition of N-linked glycosylation of the human type 1 alpha metabotropic glutamate receptor by tunicamycin: effects on cell-surface receptor expression and function
Authors: Mody, N Hermans, E Nahorski, SR Challiss, RAJ
Citation: N. Mody et al., Inhibition of N-linked glycosylation of the human type 1 alpha metabotropic glutamate receptor by tunicamycin: effects on cell-surface receptor expression and function, NEUROPHARM, 38(10), 1999, pp. 1485-1492
Cross talk between m3-muscarinic and beta(2)-adrenergic receptors at the level of receptor phosphorylation and desensitization
Authors: Budd, DC Challiss, RAJ Young, KW Tobin, AB
Citation: Dc. Budd et al., Cross talk between m3-muscarinic and beta(2)-adrenergic receptors at the level of receptor phosphorylation and desensitization, MOLEC PHARM, 56(4), 1999, pp. 813-823
Cannabinoid CB1 receptors fail to cause relaxation, but couple via G(i)/G(o) to the inhibition of adenylyl cyclase in carotid artery smooth muscle
Authors: Holland, M Challiss, RAJ Standen, NB Boyle, JP
Citation: M. Holland et al., Cannabinoid CB1 receptors fail to cause relaxation, but couple via G(i)/G(o) to the inhibition of adenylyl cyclase in carotid artery smooth muscle, BR J PHARM, 128(3), 1999, pp. 597-604
Effects of varying the expression level of recombinant human mGlu1 alpha receptors on the pharmacological properties of agonists and antagonists
Authors: Hermans, E Challiss, RAJ Nahorski, SR
Citation: E. Hermans et al., Effects of varying the expression level of recombinant human mGlu1 alpha receptors on the pharmacological properties of agonists and antagonists, BR J PHARM, 126(4), 1999, pp. 873-882
New developments in the molecular pharmacology of the myo-inositol 1,4,5-trisphosphate receptor (vol 19, pg 467, 1998)
Authors: Wilcox, RA Primrose, WU Nahorski, SR Challiss, RAJ
Citation: Ra. Wilcox et al., New developments in the molecular pharmacology of the myo-inositol 1,4,5-trisphosphate receptor (vol 19, pg 467, 1998), TRENDS PHAR, 19(12), 1998, pp. 486-486
Reversible and non-competitive antagonist profile of CPCCOEt at the human type 1 alpha metabotropic glutamate receptor
Authors: Hermans, E Nahorski, SR Challiss, RAJ
Citation: E. Hermans et al., Reversible and non-competitive antagonist profile of CPCCOEt at the human type 1 alpha metabotropic glutamate receptor, NEUROPHARM, 37(12), 1998, pp. 1645-1647
Risultati: 1-23 |