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Results: 1-21 |
Results: 21
Mutation of Tec family kinase alters T helper cell differentiation
Authors: Schaeffer, EM Yap, GS Lewis, CM Czar, MJ McVicar, DW Cheever, AW Sher, A Schwartzberg, PL
Citation: Em. Schaeffer et al., Mutation of Tec family kinase alters T helper cell differentiation, NAT IMMUNOL, 2(12), 2001, pp. 1183-1188
Disease fingerprinting with cDNA microarrays reveals distinct gene expression profiles in lethal type-1 and type-2 cytokine-mediated inflammatory reactions
Authors: Hoffmann, KF McCarty, TC Segal, DH Chiaramonte, M Hesse, M Davis, EM Cheever, AW Meltzer, PS Morse, HC Wynn, TA
Citation: Kf. Hoffmann et al., Disease fingerprinting with cDNA microarrays reveals distinct gene expression profiles in lethal type-1 and type-2 cytokine-mediated inflammatory reactions, FASEB J, 15(11), 2001, pp. NIL_233-NIL_255
Studies of murine schistosomiasis reveal interleukin-13 blockade as a treatment for established and progressive liver fibrosis
Authors: Chiaramonte, MG Cheever, AW Malley, JD Donaldson, DD Wynn, TA
Citation: Mg. Chiaramonte et al., Studies of murine schistosomiasis reveal interleukin-13 blockade as a treatment for established and progressive liver fibrosis, HEPATOLOGY, 34(2), 2001, pp. 273-282
Regulation of hepatic fibrosis and extracellular matrix genes by the Th response: New insight into the role of tissue inhibitors of matrix metalloproteinases
Authors: Vaillant, B Chiaramonte, MG Cheever, AW Soloway, PD Wynn, TA
Citation: B. Vaillant et al., Regulation of hepatic fibrosis and extracellular matrix genes by the Th response: New insight into the role of tissue inhibitors of matrix metalloproteinases, J IMMUNOL, 167(12), 2001, pp. 7017-7026
Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: Granulomatous pathology is shaped by the pattern of L-arginine metabolism
Authors: Hesse, M Modolell, M La Flamme, AC Schito, M Fuentes, JM Cheever, AW Pearce, EJ Wynn, TA
Citation: M. Hesse et al., Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: Granulomatous pathology is shaped by the pattern of L-arginine metabolism, J IMMUNOL, 167(11), 2001, pp. 6533-6544
Testing time-, ignorance-, and danger-based models of tolerance
Authors: Anderson, CC Carroll, JM Gallucci, S Ridge, JP Cheever, AW Matzinger, P
Citation: Cc. Anderson et al., Testing time-, ignorance-, and danger-based models of tolerance, J IMMUNOL, 166(6), 2001, pp. 3663-3671
Helicobacter hepaticus-induced colitis in interleukin-10-deficient mice: Cytokine requirements for the induction and maintenance of intestinal inflammation
Authors: Kullberg, MC Rothfuchs, AG Jankovic, D Caspar, P Wynn, TA Gorelick, PL Cheever, AW Sher, A
Citation: Mc. Kullberg et al., Helicobacter hepaticus-induced colitis in interleukin-10-deficient mice: Cytokine requirements for the induction and maintenance of intestinal inflammation, INFEC IMMUN, 69(7), 2001, pp. 4232-4241
Patterns of chemokine expression in models of Schistosoma mansoni inflammation and infection reveal relationships between type 1 and type 2 responsesand chemokines in vivo
Authors: Park, MK Hoffmann, KF Cheever, AW Amichay, D Wynn, TA Farber, JM
Citation: Mk. Park et al., Patterns of chemokine expression in models of Schistosoma mansoni inflammation and infection reveal relationships between type 1 and type 2 responsesand chemokines in vivo, INFEC IMMUN, 69(11), 2001, pp. 6755-6768
Immunopathology of schistosomiasis mansoni in mice and men
Authors: Cheever, AW Hoffmann, KF Wynn, TA
Citation: Aw. Cheever et al., Immunopathology of schistosomiasis mansoni in mice and men, IMMUNOL TOD, 21(9), 2000, pp. 465-466
CpG oligonucleotides can prophylactically immunize against Th2-mediated schistosome egg-induced pathology by an IL-12-independent mechanism
Authors: Chiaramonte, MG Hesse, M Cheever, AW Wynn, TA
Citation: Mg. Chiaramonte et al., CpG oligonucleotides can prophylactically immunize against Th2-mediated schistosome egg-induced pathology by an IL-12-independent mechanism, J IMMUNOL, 164(2), 2000, pp. 973-985
IL-10 and the dangers of immune polarization: Excessive type 1 and type 2 cytokine responses induce distinct forms of lethal immunopathology in murine schistosomiasis
Authors: Hoffmann, KF Cheever, AW Wynn, TA
Citation: Kf. Hoffmann et al., IL-10 and the dangers of immune polarization: Excessive type 1 and type 2 cytokine responses induce distinct forms of lethal immunopathology in murine schistosomiasis, J IMMUNOL, 164(12), 2000, pp. 6406-6416
NOS-2 mediates the protective anti-inflammatory and antifibrotic effects of the Th1-inducing adjuvant, IL-12, in a Th2 model of granulomatous disease
Authors: Hesse, M Cheever, AW Jankovic, D Wynn, TA
Citation: M. Hesse et al., NOS-2 mediates the protective anti-inflammatory and antifibrotic effects of the Th1-inducing adjuvant, IL-12, in a Th2 model of granulomatous disease, AM J PATH, 157(3), 2000, pp. 945-955
Studies with double cytokine-deficient mice reveal that highly polarized Th1-and Th2-type cytokine and antibody responses contribute equally to vaccine-induced immunity to Schistosoma mansoni
Authors: Hoffmann, KF James, SL Cheever, AW Wynn, TA
Citation: Kf. Hoffmann et al., Studies with double cytokine-deficient mice reveal that highly polarized Th1-and Th2-type cytokine and antibody responses contribute equally to vaccine-induced immunity to Schistosoma mansoni, J IMMUNOL, 163(2), 1999, pp. 927-938
Schistosome-infected IL-4 receptor knockout (KO) mice, in contrast to IL-4KO mice, fail to develop granulomatous pathology while maintaining the same lymphokine expression profile
Authors: Jankovic, D Kullberg, MC Noben-Trauth, N Caspar, P Ward, JM Cheever, AW Paul, WE Sher, A
Citation: D. Jankovic et al., Schistosome-infected IL-4 receptor knockout (KO) mice, in contrast to IL-4KO mice, fail to develop granulomatous pathology while maintaining the same lymphokine expression profile, J IMMUNOL, 163(1), 1999, pp. 337-342
IL-13 is a key regulatory cytokine for Th2 cell-mediated pulmonary granuloma formation and IgE responses induced by Schistosoma mansoni eggs
Authors: Chiaramonte, MG Schopf, LR Neben, TY Cheever, AW Donaldson, DD Wynn, TA
Citation: Mg. Chiaramonte et al., IL-13 is a key regulatory cytokine for Th2 cell-mediated pulmonary granuloma formation and IgE responses induced by Schistosoma mansoni eggs, J IMMUNOL, 162(2), 1999, pp. 920-930
Optimal vaccination against Schistosoma mansoni requires the induction of both B cell- and IFN-gamma-dependent effector mechanisms
Authors: Jankovic, D Wynn, TA Kullberg, MC Hieny, S Caspar, P James, S Cheever, AW Sher, A
Citation: D. Jankovic et al., Optimal vaccination against Schistosoma mansoni requires the induction of both B cell- and IFN-gamma-dependent effector mechanisms, J IMMUNOL, 162(1), 1999, pp. 345-351
An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response
Authors: Chiaramonte, MG Donaldson, DD Cheever, AW Wynn, TA
Citation: Mg. Chiaramonte et al., An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response, J CLIN INV, 104(6), 1999, pp. 777-785
Interleukin 5 (IL-5) is not required for expression of a Th2 response or host resistance mechanisms during murine schistosomiasis mansoni but does play a role in development of IL-4-producing non-T, non-B cells
Authors: Brunet, LR Sabin, EA Cheever, AW Kopf, MA Pearce, EJ
Citation: Lr. Brunet et al., Interleukin 5 (IL-5) is not required for expression of a Th2 response or host resistance mechanisms during murine schistosomiasis mansoni but does play a role in development of IL-4-producing non-T, non-B cells, INFEC IMMUN, 67(6), 1999, pp. 3014-3018
Egg laying is delayed but worm fecundity is normal in SCID mice infected with Schistosoma japonicum and S-mansoni with or without recombinant tumor necrosis factor alpha treatment
Authors: Cheever, AW Poindexter, RW Wynn, TA
Citation: Aw. Cheever et al., Egg laying is delayed but worm fecundity is normal in SCID mice infected with Schistosoma japonicum and S-mansoni with or without recombinant tumor necrosis factor alpha treatment, INFEC IMMUN, 67(5), 1999, pp. 2201-2208
The p47(phox-/-) mouse model of chronic granulomatous disease has normal granuloma formation and cytokine responses to Mycobacterium avium and Schistosoma mansoni eggs
Authors: Segal, BH Doherty, TM Wynn, TA Cheever, AW Sher, A Holland, SM
Citation: Bh. Segal et al., The p47(phox-/-) mouse model of chronic granulomatous disease has normal granuloma formation and cytokine responses to Mycobacterium avium and Schistosoma mansoni eggs, INFEC IMMUN, 67(4), 1999, pp. 1659-1665
Interleukin-12 can directly induce T-helper 1 responses in interferon-gamma (IFN-gamma) receptor-deficient mice, but requires IFN-gamma signalling todownregulate T-helper 2 responses
Authors: Mountford, AP Coulson, PS Cheever, AW Sher, A Wilson, RA Wynn, TA
Citation: Ap. Mountford et al., Interleukin-12 can directly induce T-helper 1 responses in interferon-gamma (IFN-gamma) receptor-deficient mice, but requires IFN-gamma signalling todownregulate T-helper 2 responses, IMMUNOLOGY, 97(4), 1999, pp. 588-594
Risultati: 1-21 |