Authors:
Szczepankiewicz, BG
Liu, G
Jae, HS
Tasker, AS
Gunawardana, IW
von Geldern, TW
Gwaltney, SL
Wu-Wong, JR
Gehrke, L
Chiou, WJ
Credo, RB
Alder, JD
Nukkala, MA
Zielinski, NA
Jarvis, K
Mollison, KW
Frost, DJ
Bauch, JL
Hui, YH
Claiborne, AK
Li, Q
Rosenberg, SH
Citation: Bg. Szczepankiewicz et al., New antimitotic agents with activity in multi-drug-resistant cell lines and in vivo efficacy in murine tumor models, J MED CHEM, 44(25), 2001, pp. 4416-4430
Authors:
Jae, HS
Winn, M
von Geldern, TW
Sorensen, BK
Chiou, WJ
Nguyen, B
Marsh, KC
Opgenorth, TJ
Citation: Hs. Jae et al., Pyrrolidine-3-carboxylic acids as endothelin antagonists. 5. Highly selective, potent, and orally active ETA antagonists, J MED CHEM, 44(23), 2001, pp. 3978-3984
Authors:
Chiou, WJ
Wessale, JL
von Geldern, T
Opgenorth, TJ
Wu-Wong, JR
Citation: Wj. Chiou et al., 'Irreversible' endothelin-1 binding does not prohibit ABT-627 from reversing endothelin-1-induced effects, J CARDIO PH, 36, 2000, pp. S48-S52
Authors:
Dayton, BD
Chiou, WJ
Opgenorth, TJ
Wu-Wong, JR
Citation: Bd. Dayton et al., Direct determination of endothelin receptor antagonist levels in plasma using a scintillation proximity assay, LIFE SCI, 66(10), 2000, pp. 937-945
Authors:
Boyd, SA
Mantei, RA
Tasker, AS
Liu, G
Sorensen, BK
Henry, KJ
von Geldern, TW
Winn, M
Wu-Wong, JSR
Chiou, WJ
Dixon, DB
Hutchins, CW
Marsh, KC
Nguyen, E
Opgenorth, TJ
Citation: Sa. Boyd et al., Discovery of a series of pyrrolidine-based endothelin receptor antagonistswith enhanced ETA receptor selectivity, BIO MED CH, 7(6), 1999, pp. 991-1002
Authors:
von Geldern, TW
Tasker, AS
Sorensen, BK
Winn, M
Szczepankiewicz, BG
Dixon, DB
Chiou, WJ
Wang, LM
Wessale, JL
Adler, A
Marsh, KC
Nguyen, E
Opgenorth, TJ
Citation: Tw. Von Geldern et al., Pyrrolidine-3-carboxylic acids as endothelin antagonists. 4. Side chain conformational restriction leads to ETB selectivity, J MED CHEM, 42(18), 1999, pp. 3668-3678
Authors:
Liu, G
Kozmina, NS
Winn, M
von Geldern, TW
Chiou, WJ
Dixon, DB
Nguyen, E
Marsh, KC
Opgenorth, TJ
Citation: G. Liu et al., Design, synthesis, and activity of a series of pyrrolidine-3-carboxylic acid-based, highly specific, orally active ETB antagonists containing a diphenylmethylamine acetamide side chain, J MED CHEM, 42(18), 1999, pp. 3679-3689
Authors:
Wu-Wong, JSR
Berg, CE
Wang, JH
Chiou, WJ
Fissel, B
Citation: Jsr. Wu-wong et al., Endothelin stimulates glucose uptake and GLUT4 translocation via activation of endothelin ETA receptor in 3T3-L1 adipocytes, J BIOL CHEM, 274(12), 1999, pp. 8103-8110
Authors:
Wu-Wong, JSR
Dixon, DB
Chiou, WJ
Dayton, BD
Novosad, EI
Adler, AL
Wessale, JL
Calzadilla, SV
Hernandez, L
Marsh, KC
Liu, G
Szczepankiewicz, B
von Geldern, TW
Opgenorth, TJ
Citation: Jsr. Wu-wong et al., Pharmacology of A-216546: a highly selective antagonist for endothelin ETAreceptor, EUR J PHARM, 366(2-3), 1999, pp. 189-201