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Results: 1-23 |
Results: 23
pH-Induced conformational transitions of a molten-globule-like state of the inhibitory prodomain of furin: Implications for zymogen activation
Authors: Bhattacharjya, S Xu, P Xiang, H Chretien, M Seidah, NG Ni, F
Citation: S. Bhattacharjya et al., pH-Induced conformational transitions of a molten-globule-like state of the inhibitory prodomain of furin: Implications for zymogen activation, PROTEIN SCI, 10(5), 2001, pp. 934-942
Elevated expression of proprotein convertases alters breast cancer cell growth in response to estrogen and tamoxifen
Authors: Cheng, M Xu, N Iwasiow, B Seidah, N Chretien, M Shiu, RPC
Citation: M. Cheng et al., Elevated expression of proprotein convertases alters breast cancer cell growth in response to estrogen and tamoxifen, J MOL ENDOC, 26(2), 2001, pp. 95-105
Neuroendocrine secretory protein 7B2: structure, expression and functions
Authors: Mbikay, M Seidah, NG Chretien, M
Citation: M. Mbikay et al., Neuroendocrine secretory protein 7B2: structure, expression and functions, BIOCHEM J, 357, 2001, pp. 329-342
Implication of the proprotein convertases furin, PC5 and PC7 in the cleavage of surface glycoproteins of Hong Kong, Ebola and respiratory syncytial viruses: a comparative analysis with fluorogenic peptides
Authors: Basak, A Zhong, M Munzer, JS Chretien, M Seidah, NG
Citation: A. Basak et al., Implication of the proprotein convertases furin, PC5 and PC7 in the cleavage of surface glycoproteins of Hong Kong, Ebola and respiratory syncytial viruses: a comparative analysis with fluorogenic peptides, BIOCHEM J, 353, 2001, pp. 537-545
The testicular germ-cell protease PC4 is also expressed in macrophage-likecells of the ovary
Authors: Tadros, H Chretien, M Mbikay, M
Citation: H. Tadros et al., The testicular germ-cell protease PC4 is also expressed in macrophage-likecells of the ovary, J REPRO IMM, 49(2), 2001, pp. 133-152
Selective expression of the proprotein convertases furin, PC5, and PC7 in proliferating vascular smooth muscle cells of the rat aorta in vitro
Authors: Stawowy, P Marcinkiewicz, J Graf, K Seidah, NG Chretien, M Fleck, E Marcinkiewicz, M
Citation: P. Stawowy et al., Selective expression of the proprotein convertases furin, PC5, and PC7 in proliferating vascular smooth muscle cells of the rat aorta in vitro, J HIST CYTO, 49(3), 2001, pp. 323-331
Inhibitory specificity and potency of proSAAS-derived peptides toward proprotein convertase 1
Authors: Basak, A Koch, P Dupelle, M Fricker, LD Devi, LA Chretien, M Seidah, NG
Citation: A. Basak et al., Inhibitory specificity and potency of proSAAS-derived peptides toward proprotein convertase 1, J BIOL CHEM, 276(35), 2001, pp. 32720-32728
Inhibition of proprotein convertases is associated with loss of growth andtumorigenicity of HT-29 human colon carcinoma cells - Importance of insulin-like growth factor-1 (IGF-1) receptor processing in IGF-1-mediated functions
Authors: Khatib, AM Siegfried, G Prat, A Luis, J Chretien, M Metrakos, P Seidah, NG
Citation: Am. Khatib et al., Inhibition of proprotein convertases is associated with loss of growth andtumorigenicity of HT-29 human colon carcinoma cells - Importance of insulin-like growth factor-1 (IGF-1) receptor processing in IGF-1-mediated functions, J BIOL CHEM, 276(33), 2001, pp. 30686-30693
Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding - The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production
Authors: Benjannet, S Elagoz, A Wickham, L Mamarbachi, M Munzer, JS Basak, A Lazure, C Cromlish, JA Sisodia, S Checler, F Chretien, M Seidah, NG
Citation: S. Benjannet et al., Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding - The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production, J BIOL CHEM, 276(14), 2001, pp. 10879-10887
Endoproteolytic processing of integrin pro-alpha subunits involves the redundant function of furin and proprotein convertase (PC) 5A, but not paired basic amino acid converting enzyme (PACE) 4, PC5B or PC7
Authors: Lissitzky, JC Luis, J Munzer, JS Benjannet, S Parat, F Chretien, M Marvaldi, J Seidah, NG
Citation: Jc. Lissitzky et al., Endoproteolytic processing of integrin pro-alpha subunits involves the redundant function of furin and proprotein convertase (PC) 5A, but not paired basic amino acid converting enzyme (PACE) 4, PC5B or PC7, BIOCHEM J, 346, 2000, pp. 133-138
A variable speed translating couch technique for total body irradiation
Authors: Chretien, M Cote, C Blais, R Brouard, L Roy-Lacroix, L Larochelle, M Roy, R Pouliot, J
Citation: M. Chretien et al., A variable speed translating couch technique for total body irradiation, MED PHYS, 27(5), 2000, pp. 1127-1130
Biosynthesis and enzymatic characterization of human SKI-1/S1P and the processing of its inhibitory prosegment
Authors: Toure, BB Munzer, JS Basak, A Benjannet, S Rochemont, J Lazure, C Chretien, M Seidah, NG
Citation: Bb. Toure et al., Biosynthesis and enzymatic characterization of human SKI-1/S1P and the processing of its inhibitory prosegment, J BIOL CHEM, 275(4), 2000, pp. 2349-2358
Inhibitory activity and structural characterization of a C-terminal peptide fragment derived from the prosegment of the proprotein convertase PC7
Authors: Bhattacharjya, S Xu, P Zhong, M Chretien, M Seidah, NG Ni, F
Citation: S. Bhattacharjya et al., Inhibitory activity and structural characterization of a C-terminal peptide fragment derived from the prosegment of the proprotein convertase PC7, BIOCHEM, 39(11), 2000, pp. 2868-2877
Cathepsin-B fusion proteins misroute secretory protein partners such as the proprotein convertase PC2-7B2 complex toward the lysosomal degradation pathways
Authors: Rovere, C Mort, JS Chretien, M Seidah, NG
Citation: C. Rovere et al., Cathepsin-B fusion proteins misroute secretory protein partners such as the proprotein convertase PC2-7B2 complex toward the lysosomal degradation pathways, BIOC BIOP R, 276(2), 2000, pp. 594-599
Enzymic characterization in vitro of recombinant proprotein convertase PC4
Authors: Basak, A Toure, BB Lazure, C Mbikay, M Chretien, M Seidah, NG
Citation: A. Basak et al., Enzymic characterization in vitro of recombinant proprotein convertase PC4, BIOCHEM J, 343, 1999, pp. 29-37
Inhibition of proprotein convertases-1, -7 and furin by diterpines of Andrographis paniculata and their succinoyl esters
Authors: Basak, A Cooper, S Roberge, AG Banik, UK Chretien, M Seidah, NG
Citation: A. Basak et al., Inhibition of proprotein convertases-1, -7 and furin by diterpines of Andrographis paniculata and their succinoyl esters, BIOCHEM J, 338, 1999, pp. 107-113
Clinical relevance of convertases: atherosclerosis, Alzheimer's disease, obesity, diabetes and HIV
Authors: Chretien, M
Citation: M. Chretien, Clinical relevance of convertases: atherosclerosis, Alzheimer's disease, obesity, diabetes and HIV, CLIN INV M, 22(5), 1999, pp. 207-211
Mammalian subtilisin kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization
Authors: Seidah, NG Mowla, SJ Hamelin, J Mamarbachi, AM Benjannet, S Toure, BB Basak, A Munzer, JS Marcinkiewicz, J Zhong, M Barale, JC Lazure, C Murphy, RA Chretien, M Marcinkiewicz, M
Citation: Ng. Seidah et al., Mammalian subtilisin kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization, P NAS US, 96(4), 1999, pp. 1321-1326
Nerve growth factor and proprotein convertases furin and PC7 in transectedsciatic nerves and in nerve segments cultured in conditioned media: Their presence in Schwann cells, macrophages, and smooth muscle cells
Authors: Marcinkiewicz, M Marcinkiewicz, J Chen, A Leclaire, F Chretien, M Richardson, P
Citation: M. Marcinkiewicz et al., Nerve growth factor and proprotein convertases furin and PC7 in transectedsciatic nerves and in nerve segments cultured in conditioned media: Their presence in Schwann cells, macrophages, and smooth muscle cells, J COMP NEUR, 403(4), 1999, pp. 471-485
The prosegments of furin and PC7 as potent inhibitors of proprotein convertases - In vitro and ex vivo assessment of their efficacy and selectivity
Authors: Zhong, M Munzer, JS Basak, A Benjannet, S Mowla, SJ Decroly, E Chretien, M Seidah, NG
Citation: M. Zhong et al., The prosegments of furin and PC7 as potent inhibitors of proprotein convertases - In vitro and ex vivo assessment of their efficacy and selectivity, J BIOL CHEM, 274(48), 1999, pp. 33913-33920
The RGD motif and the C-terminal segment of proprotein convertase 1 are critical for its cellular trafficking but not for its intracellular binding to integrin alpha(5)beta(1)
Authors: Rovere, C Luis, J Lissitzky, JC Basak, A Marvaldi, J Chretien, M Seidah, NG
Citation: C. Rovere et al., The RGD motif and the C-terminal segment of proprotein convertase 1 are critical for its cellular trafficking but not for its intracellular binding to integrin alpha(5)beta(1), J BIOL CHEM, 274(18), 1999, pp. 12461-12467
Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides
Authors: Seidah, NG Chretien, M
Citation: Ng. Seidah et M. Chretien, Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides, BRAIN RES, 848(1-2), 1999, pp. 45-62
Molecular characterization, enzymatic analysis, and purification of murineproprotein convertase-1/3 (PC1/PC3) secreted from recombinant baculovirus-infected insect cells
Authors: Boudreault, A Gauthier, D Rondeau, N Savaria, D Seidah, NG Chretien, M Lazure, C
Citation: A. Boudreault et al., Molecular characterization, enzymatic analysis, and purification of murineproprotein convertase-1/3 (PC1/PC3) secreted from recombinant baculovirus-infected insect cells, PROT EX PUR, 14(3), 1998, pp. 353-366
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