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Results: 1-20 |
Results: 20
Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation
Authors: Luo, Y Bolon, B Kahn, S Bennett, BD Babu-Khan, S Denis, P Fan, W Kha, H Zhang, JH Gong, YH Martin, L Louis, JC Yan, Q Richards, WG Citron, M Vassar, R
Citation: Y. Luo et al., Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation, NAT NEUROSC, 4(3), 2001, pp. 231-232
Caucasian family with two independent mutations: 2594delC in BRCA1 and 5392delAG in BRCA2 gene
Authors: Ganguly, A Citron, M Godmilow, L Ahrens, M Ganguly, T
Citation: A. Ganguly et al., Caucasian family with two independent mutations: 2594delC in BRCA1 and 5392delAG in BRCA2 gene, AM J MED G, 101(2), 2001, pp. 146-152
A furin-like convertase mediates propeptide cleavage of BACE, the Alzheimer's beta-secretase (vol 275, pg 37712, 2000)
Authors: Bennett, BD Denis, P Haniu, M Teplow, DB Kahn, S Louis, JC Citron, M Vassar, R
Citation: Bd. Bennett et al., A furin-like convertase mediates propeptide cleavage of BACE, the Alzheimer's beta-secretase (vol 275, pg 37712, 2000), J BIOL CHEM, 276(18), 2001, pp. 15561-15561
Characterization of Alzheimer's beta-secretase protein BACE: Processing and other post-translational modifications
Authors: Haniu, M Bennett, BD Denis, P Young, Y Mendiaz, EA Fuller, J Hui, JO Kahn, S Babu-Khan, S Ross, S Burgess, T Katta, V Nicolson, M Lull, J Wang, SY Rogers, G Vassar, R Citron, M
Citation: M. Haniu et al., Characterization of Alzheimer's beta-secretase protein BACE: Processing and other post-translational modifications, ALZHEIMER'S DISEASE, 2001, pp. 739-745
Secretases as targets for the treatment of Alzheimer's disease
Authors: Citron, M
Citation: M. Citron, Secretases as targets for the treatment of Alzheimer's disease, MOL MED TOD, 6(10), 2000, pp. 392-397
A beta-generating enzymes: Recent advances in beta- and gamma-secretase research
Authors: Vassar, R Citron, M
Citation: R. Vassar et M. Citron, A beta-generating enzymes: Recent advances in beta- and gamma-secretase research, NEURON, 27(3), 2000, pp. 419-422
Fenchylamine sulfonamide inhibitors of amyloid beta peptide production by the gamma-secretase proteolytic pathway: Potential small-molecule therapeutic agents for the treatment of Alzheimer's disease
Authors: Rishton, GM Retz, DM Tempest, PA Novotny, J Kahn, S Treanor, JJS Lile, JD Citron, M
Citation: Gm. Rishton et al., Fenchylamine sulfonamide inhibitors of amyloid beta peptide production by the gamma-secretase proteolytic pathway: Potential small-molecule therapeutic agents for the treatment of Alzheimer's disease, J MED CHEM, 43(12), 2000, pp. 2297-2299
A furin-like convertase mediates propeptide cleavage of BACE, the Alzheimer's beta-secretase
Authors: Bennett, BD Denis, P Haniu, M Teplow, DB Kahn, S Louis, JC Citron, M Vassar, R
Citation: Bd. Bennett et al., A furin-like convertase mediates propeptide cleavage of BACE, the Alzheimer's beta-secretase, J BIOL CHEM, 275(48), 2000, pp. 37712-37717
Parkinson's disease-associated alpha-sylnuclein is more fibrillogenic thanbeta- and gamma-synuclein and cannot cross-seed its homologs
Authors: Biere, AL Wood, SJ Wypych, J Steavenson, S Jiang, YJ Anafi, D Jacobsen, FW Jarosinski, MA Wu, GM Louis, JC Martin, F Narhi, LO Citron, M
Citation: Al. Biere et al., Parkinson's disease-associated alpha-sylnuclein is more fibrillogenic thanbeta- and gamma-synuclein and cannot cross-seed its homologs, J BIOL CHEM, 275(44), 2000, pp. 34574-34579
Characterization of Alzheimer's beta-secretase protein BACE - A pepsin family member with unusual properties
Authors: Haniu, M Denis, P Young, Y Mendiaz, EA Fuller, J Hui, JO Bennett, BD Kahn, S Ross, S Burgess, T Katta, V Rogers, G Vassar, R Citron, M
Citation: M. Haniu et al., Characterization of Alzheimer's beta-secretase protein BACE - A pepsin family member with unusual properties, J BIOL CHEM, 275(28), 2000, pp. 21099-21106
Expression analysis of BACE2 in brain and peripheral tissues
Authors: Bennett, BD Babu-Khan, S Loeloff, R Louis, JC Curran, E Citron, M Vassar, R
Citation: Bd. Bennett et al., Expression analysis of BACE2 in brain and peripheral tissues, J BIOL CHEM, 275(27), 2000, pp. 20647-20651
beta-secretase - Tissue culture studies of sequence specificity, inhibitors, and candidate enzymes
Authors: Citron, M
Citation: M. Citron, beta-secretase - Tissue culture studies of sequence specificity, inhibitors, and candidate enzymes, METH MOL M, 32, 2000, pp. 229-238
beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
Authors: Vassar, R Bennett, BD Babu-Khan, S Kahn, S Mendiaz, EA Denis, P Teplow, DB Ross, S Amarante, P Loeloff, R Luo, Y Fisher, S Fuller, L Edenson, S Lile, J Jarosinski, MA Biere, AL Curran, E Burgess, T Louis, JC Collins, F Treanor, J Rogers, G Citron, M
Citation: R. Vassar et al., beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE, SCIENCE, 286(5440), 1999, pp. 735-741
A loss of function mutation of presenilin-2 interferes with amyloid beta-peptide production and notch signaling
Authors: Steiner, H Duff, K Capell, A Romig, H Grim, MG Lincoln, S Hardy, J Yu, X Picciano, M Fechteler, K Citron, M Kopan, R Pesold, B Keck, S Baader, M Tomita, T Iwatsubo, T Baumeister, R Haass, C
Citation: H. Steiner et al., A loss of function mutation of presenilin-2 interferes with amyloid beta-peptide production and notch signaling, J BIOL CHEM, 274(40), 1999, pp. 28669-28673
alpha-synuclein fibrillogenesis is nucleation-dependent - Implications forthe pathogenesis of Parkinson's disease
Authors: Wood, SJ Wypych, J Steavenson, S Louis, JC Citron, M Biere, AL
Citation: Sj. Wood et al., alpha-synuclein fibrillogenesis is nucleation-dependent - Implications forthe pathogenesis of Parkinson's disease, J BIOL CHEM, 274(28), 1999, pp. 19509-19512
Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation (vol 274, pg 9843, 1999)
Authors: Narhi, L Wood, SJ Steavenson, S Jiang, YJ Wu, GM Anafi, D Kaufman, SA Martin, F Sitney, K Denis, P Louis, JC Wypych, J Biere, AL Citron, M
Citation: L. Narhi et al., Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation (vol 274, pg 9843, 1999), J BIOL CHEM, 274(19), 1999, pp. 13728-13728
Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation
Authors: Narhi, L Wood, SJ Steavenson, S Jiang, YJ Wu, GM Anafi, D Kaufman, SA Martin, F Sitney, K Denis, P Louis, JC Wypych, J Biere, AL Citron, M
Citation: L. Narhi et al., Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation, J BIOL CHEM, 274(14), 1999, pp. 9843-9846
The biological and pathological function of the presenilin-1 Delta exon 9 mutation is independent of its defect to undergo proteolytic processing
Authors: Steiner, H Romig, H Grim, MG Philipp, U Pesold, B Citron, M Baumeister, R Haass, C
Citation: H. Steiner et al., The biological and pathological function of the presenilin-1 Delta exon 9 mutation is independent of its defect to undergo proteolytic processing, J BIOL CHEM, 274(12), 1999, pp. 7615-7618
Self-help groups for families of persons with mental illness: Perceived benefits of helpfulness
Authors: Citron, M Solomon, P Draine, J
Citation: M. Citron et al., Self-help groups for families of persons with mental illness: Perceived benefits of helpfulness, COMM MENT H, 35(1), 1999, pp. 15-30
Amyloidogenic function of the Alzheimer's disease-associated presenilin 1 in the absence of endoproteolysis
Authors: Steiner, H Romig, H Pesold, B Philipp, U Baader, M Citron, M Loetscher, H Jacobsen, H Haass, C
Citation: H. Steiner et al., Amyloidogenic function of the Alzheimer's disease-associated presenilin 1 in the absence of endoproteolysis, BIOCHEM, 38(44), 1999, pp. 14600-14605
Risultati: 1-20 |