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Results:
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Results: 24
Authors:
Muller, S
Coombs, GH
Walter, RD
Citation: S. Muller et al., Targeting polyamines of parasitic protozoa in chemotherapy, TRENDS PARA, 17(5), 2001, pp. 242-249
Authors:
Coombs, GH
Goldberg, DE
Klemba, M
Berry, C
Kay, J
Mottram, JC
Citation: Gh. Coombs et al., Aspartic proteases of Plasmodium falciparum and other parasitic protozoa as drug targets, TRENDS PARA, 17(11), 2001, pp. 532-537
Authors:
Stentiford, GD
Neil, DM
Coombs, GH
Citation: Gd. Stentiford et al., Development and application of an immunoassay diagnostic technique for studying Hematodinium infections in Nephrops norvegicus populations, DIS AQU ORG, 46(3), 2001, pp. 223-229
Authors:
Alves, LC
Melo, RL
Cezari, MHS
Sanderson, SJ
Mottram, JC
Coombs, GH
Juliano, L
Juliano, MA
Citation: Lc. Alves et al., Analysis of the S-2 subsite specificities of the recombinant cysteine proteinases CPB of Leishmania mexicana, and cruzain of Trypanosoma cruzi, usingfluorescent substrates containing non-natural basic amino acids, MOL BIOCH P, 117(2), 2001, pp. 137-143
Authors:
Alves, LC
Judice, WAS
St Hilaire, PM
Meldal, M
Sanderson, SJ
Mottram, JC
Coombs, GH
Juliano, L
Juliano, MA
Citation: Lc. Alves et al., Substrate specificity of recombinant cysteine proteinase, CPB, of Leishmania mexicana, MOL BIOCH P, 116(1), 2001, pp. 1-9
Authors:
Alves, LC
St Hilaire, PM
Meldal, M
Sanderson, SJ
Mottram, JC
Coombs, GH
Juliano, L
Juliano, MA
Citation: Lc. Alves et al., Identification of peptides inhibitory to recombinant cysteine proteinase, CPB, of Leishmania mexicana, MOL BIOCH P, 114(1), 2001, pp. 81-88
Authors:
Coombs, GH
Mottram, JC
Citation: Gh. Coombs et Jc. Mottram, Trifluoromethionine, a prodrug designed against methionine gamma-lyase-containing pathogens, has efficacy in vitro and in vivo against Trichomonas vaginalis, ANTIM AG CH, 45(6), 2001, pp. 1743-1745
Authors:
Alves, LC
Melo, RL
Sanderson, SJ
Mottram, JC
Coombs, GH
Caliendo, G
Santagada, V
Juliano, L
Juliano, MA
Citation: Lc. Alves et al., S-1 subsite specificity of a recombinant cysteine proteinase, CPB, of Leishmania mexicana compared with cruzain, human cathepsin L and papain using substrates containing non-natural basic amino acids, EUR J BIOCH, 268(5), 2001, pp. 1206-1212
Authors:
St Hilaire, PM
Alves, LC
Sanderson, SJ
Mottram, JC
Juliano, MA
Juliano, L
Coombs, GH
Meldal, M
Citation: Pm. St Hilaire et al., The substrate specificity of a recombinant cysteine protease from Leishmania mexicana: Application of a combinatorial peptide library approach, CHEMBIOCHEM, 1(2), 2000, pp. 115-122
Authors:
Hilley, JD
Zawadzki, JL
McConville, MJ
Coombs, GH
Mottram, JC
Citation: Jd. Hilley et al., Leishmania mexicana mutants lacking glycosylphosphatidylinositol (GPI): Protein transamidase provide insights into the biosynthesis and functions of GPI-anchored proteins, MOL BIOL CE, 11(4), 2000, pp. 1183-1195
Authors:
Brooks, DR
McCulloch, R
Coombs, GH
Mottram, JC
Citation: Dr. Brooks et al., Stable transformation of trypanosomatids through targeted chromosomal integration of the selectable marker gene encoding blasticidin S deaminase, FEMS MICROB, 186(2), 2000, pp. 287-291
Authors:
Sharma, DK
Hilley, JD
Bangs, JD
Coombs, GH
Mottram, JC
Menon, AK
Citation: Dk. Sharma et al., Soluble GP18 restores glycosylphosphatidylinositol anchoring in a trypanosome cell-free system depleted of lumenal endoplasmic reticulum proteins, BIOCHEM J, 351, 2000, pp. 717-722
Authors:
Sanderson, SJ
Pollock, KGJ
Hilley, JD
Meldal, M
St Hilaire, P
Juliano, MA
Juliano, L
Mottram, JC
Coombs, GH
Citation: Sj. Sanderson et al., Expression and characterization of a recombinant cysteine proteinase of Leishmania mexicana, BIOCHEM J, 347, 2000, pp. 383-388
Authors:
Stentiford, GD
Neil, DM
Coombs, GH
Citation: Gd. Stentiford et al., Alterations in the biochemistry and ultrastructure of the deep abdominal flexor muscle of the Norway lobster Nephrops norvegicus during infection by a parasitic dinoflagellate of the genus Hematodinium, DIS AQU ORG, 42(2), 2000, pp. 133-141
Authors:
Basselin, M
Coombs, GH
Barrett, MP
Citation: M. Basselin et al., Putrescine and spermidine transport in Leishmania, MOL BIOCH P, 109(1), 2000, pp. 37-46
Authors:
Frame, MJ
Mottram, JC
Coombs, GH
Citation: Mj. Frame et al., Analysis of the roles of cysteine proteinases of Leishmania mexicana in the host-parasite interaction, PARASITOL, 121, 2000, pp. 367-377
Authors:
Brooks, DR
Tetley, L
Coombs, GH
Mottram, JC
Citation: Dr. Brooks et al., Processing and trafficking of cysteine proteases in Leishmania mexicana, J CELL SCI, 113(22), 2000, pp. 4035-4041
Authors:
Stentiford, GD
Neil, DM
Coombs, GH
Citation: Gd. Stentiford et al., Changes in the plasma free amino acid profile of the Norway lobster Nephrops norvegicus at different stages of infection by a parasitic dinoflagellate (genus Hematodinium), DIS AQU ORG, 38(2), 1999, pp. 151-157
Authors:
Coombs, GH
Citation: Gh. Coombs, Biochemical peculiarities and drug targets in Cryptosporidium parvum: Lessons from other coccidian parasites, PARASIT TOD, 15(8), 1999, pp. 333-338
Authors:
Krauth-Siegel, RL
Coombs, GH
Citation: Rl. Krauth-siegel et Gh. Coombs, Enzymes of parasite thiol metabolism as drug targets, PARASIT TOD, 15(10), 1999, pp. 404-409
Authors:
Roberts, CW
Finnerty, J
Johnson, JJ
Roberts, F
Kyle, DE
Krell, T
Coggins, JR
Coombs, GH
Milhous, WK
Tzipori, S
Ferguson, DJP
Chakrabarti, D
McLeod, R
Citation: Cw. Roberts et al., Shikimate pathway in apicomplexan parasites - Reply, NATURE, 397(6716), 1999, pp. 220-220
Authors:
Vickerman, K
Coombs, GH
Citation: K. Vickerman et Gh. Coombs, Protozoan paradigms for cell biology, J CELL SCI, 112(17), 1999, pp. 2797-2798
Authors:
Tetley, L
Brown, SMA
McDonald, V
Coombs, GH
Citation: L. Tetley et al., Ultrastructural analysis of the sporozoite of Cryptosporidium parvum, MICROBIO-UK, 144, 1998, pp. 3249-3255
Authors:
Alexander, J
Coombs, GH
Mottram, JC
Citation: J. Alexander et al., Leishmania mexicana cysteine proteinase-deficient mutants have attenuated virulence for mice and potentiate a TH1 response, J IMMUNOL, 161(12), 1998, pp. 6794-6801
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