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Results: 1-9 |
Results: 9
Using GSTP1-1 to generate mechanism-based competitive inhibitors of the anticancer target enzyme glyoxalase I
Authors: Hamilton, DS Creighton, DJ
Citation: Ds. Hamilton et Dj. Creighton, Using GSTP1-1 to generate mechanism-based competitive inhibitors of the anticancer target enzyme glyoxalase I, CHEM-BIO IN, 133(1-3), 2001, pp. 355-359
Brief history of glyoxalase I and what we have learned about metal ion-dependent, enzyme-catalyzed isomerizations
Authors: Creighton, DJ Hamilton, DS
Citation: Dj. Creighton et Ds. Hamilton, Brief history of glyoxalase I and what we have learned about metal ion-dependent, enzyme-catalyzed isomerizations, ARCH BIOCH, 387(1), 2001, pp. 1-10
Reaction of COTC with glutathione: structure of the putative glyoxalase I inhibitor
Authors: Huntley, CFM Hamilton, DS Creighton, DJ Ganem, B
Citation: Cfm. Huntley et al., Reaction of COTC with glutathione: structure of the putative glyoxalase I inhibitor, ORG LETT, 2(20), 2000, pp. 3143-3144
Pharmacokinetics and antitumor properties in tumor-bearing mice of an enediol analogue inhibitor of glyoxalase I
Authors: Sharkey, EM O'Neill, HB Kavarana, MJ Wang, HB Creighton, DJ Sentz, DL Eiseman, JL
Citation: Em. Sharkey et al., Pharmacokinetics and antitumor properties in tumor-bearing mice of an enediol analogue inhibitor of glyoxalase I, CANC CHEMOT, 46(2), 2000, pp. 156-166
Role of hydrophobic interactions in binding S-(N-aryl/alkyl-N-hydroxycarbamoyl)glutathiones to the active site of the antitumor target enzyme glyoxalase I
Authors: Kalsi, A Kavarana, MJ Lu, TF Whalen, DL Hamilton, DS Creighton, DJ
Citation: A. Kalsi et al., Role of hydrophobic interactions in binding S-(N-aryl/alkyl-N-hydroxycarbamoyl)glutathiones to the active site of the antitumor target enzyme glyoxalase I, J MED CHEM, 43(21), 2000, pp. 3981-3986
Lentivirus-derived antimicrobial peptides: increased potency by sequence engineering and dimerization
Authors: Tencza, SB Creighton, DJ Yuan, T Vogel, HJ Montelaro, RC Mietzner, TA
Citation: Sb. Tencza et al., Lentivirus-derived antimicrobial peptides: increased potency by sequence engineering and dimerization, J ANTIMICRO, 44(1), 1999, pp. 33-41
Mechanism-based competitive inhibitors of glyoxalase I: Intracellular delivery, in vitro antitumor activities, and stabilities in human serum and mouse serum
Authors: Kavarana, MJ Kovaleva, EG Creighton, DJ Wollman, MB Eiseman, JL
Citation: Mj. Kavarana et al., Mechanism-based competitive inhibitors of glyoxalase I: Intracellular delivery, in vitro antitumor activities, and stabilities in human serum and mouse serum, J MED CHEM, 42(2), 1999, pp. 221-228
A new method for rapidly generating inhibitors of glyoxalase I inside tumor using S(N-aryl-N-hydroxycarbamoyl)ethylsulfoxides
Authors: Hamilton, DS Kavarana, MJ Sharkey, EM Eiseman, JL Creighton, DJ
Citation: Ds. Hamilton et al., A new method for rapidly generating inhibitors of glyoxalase I inside tumor using S(N-aryl-N-hydroxycarbamoyl)ethylsulfoxides, J MED CHEM, 42(10), 1999, pp. 1823-1827
Reaction mechanism of glyoxalase I explored by an X-ray crystallographic analysis of the human enzyme in complex with a transition state analogue
Authors: Cameron, AD Ridderstrom, M Olin, B Kavarana, MJ Creighton, DJ Mannervik, B
Citation: Ad. Cameron et al., Reaction mechanism of glyoxalase I explored by an X-ray crystallographic analysis of the human enzyme in complex with a transition state analogue, BIOCHEM, 38(41), 1999, pp. 13480-13490
Risultati: 1-9 |