Authors:
Annaert, WG
Esselens, C
Baert, V
Boeve, C
Snellings, G
Cupers, P
Craessaerts, K
De Strooper, B
Citation: Wg. Annaert et al., Interaction with telencephalin and the amyloid precursor protein predicts a ring structure for presenilins, NEURON, 32(4), 2001, pp. 579-589
Authors:
Cupers, P
Orlans, I
Craessaerts, K
Annaert, W
De Strooper, B
Citation: P. Cupers et al., The amyloid precursor protein (APP)-cytoplasmic fragment generated by gamma-secretase is rapidly degraded but distributes partially in a nuclear fraction of neurones in culture, J NEUROCHEM, 78(5), 2001, pp. 1168-1178
Authors:
Cupers, P
Bentahir, M
Craessaerts, K
Orlans, I
Vanderstichele, H
Saftig, P
De Strooper, B
Annaert, W
Citation: P. Cupers et al., The discrepancy between presenilin subcellular localization and gamma-secretase processing of amyloid precursor protein, J CELL BIOL, 154(4), 2001, pp. 731-740
Authors:
Wiltfang, J
Esselmann, H
Cupers, P
Neumann, M
Kretzschmar, H
Beyermann, M
Schleuder, D
Jahn, H
Ruther, E
Kornhuber, J
Annaert, W
De Strooper, B
Saftig, P
Citation: J. Wiltfang et al., Elevation of beta-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PS1 knockout cells, J BIOL CHEM, 276(46), 2001, pp. 42645-42657
Authors:
Boeve, CMA
Cupers, P
Van Leuven, F
Annaert, W
De Strooper, B
Citation: Cma. Boeve et al., Membrane orientation of the Alzheimer's disease - Associated presenilins, MEMBRANE STRUCTURE IN DISEASE AND DRUG THERAPY, 2000, pp. 353-368
Authors:
De Strooper, B
Annaert, W
Cupers, P
Saftig, P
Craessaerts, K
Mumm, JS
Schroeter, EH
Schrijvers, V
Wolfe, MS
Ray, WJ
Goate, A
Kopan, R
Citation: B. De Strooper et al., A presenilin-1-dependent gamma-secretase-like protease mediates release ofNotch intracellular domain, NATURE, 398(6727), 1999, pp. 518-522
Authors:
Herreman, A
Hartmann, D
Annaert, W
Saftig, P
Craessaerts, K
Serneels, L
Umans, L
Schrijvers, V
Checler, F
Vanderstichele, H
Baekelandt, V
Dressel, R
Cupers, P
Huylebroeck, D
Zwijsen, A
Van Leuven, F
De Strooper, B
Citation: A. Herreman et al., Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency, P NAS US, 96(21), 1999, pp. 11872-11877