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Results: 1-12 |
Results: 12
HUMAN SERUM ATTENUATES THE ACTIVITY OF PROTEASE INHIBITORS TOWARD WILD-TYPE AND MUTANT HUMAN-IMMUNODEFICIENCY-VIRUS
Authors: MOLLA A VASAVANONDA S KUMAR G SHAM HL JOHNSON M GRABOWSKI B DENISSEN JF KOHLBRENNER W PLATTNER JJ LEONARD JM NORBECK DW KEMPF DJ
Citation: A. Molla et al., HUMAN SERUM ATTENUATES THE ACTIVITY OF PROTEASE INHIBITORS TOWARD WILD-TYPE AND MUTANT HUMAN-IMMUNODEFICIENCY-VIRUS, Virology (New York, N.Y. Print), 250(2), 1998, pp. 255-262
DISCOVERY AND EVALUATION OF A SERIES OF 3-ACYLINDOLE IMIDAZOPYRIDINE PLATELET-ACTIVATING-FACTOR ANTAGONISTS
Authors: CURTIN ML DAVIDSEN SK HEYMAN HR GARLAND RB SHEPPARD GS FLORJANCIC AS XU LH CARRERA GM STEINMAN DH TRAUTMANN JA ALBERT DH MAGOC TJ TAPANG P RHEIN DA CONWAY RG LUO GJ DENISSEN JF MARSH KC MORGAN DW SUMMERS JB
Citation: Ml. Curtin et al., DISCOVERY AND EVALUATION OF A SERIES OF 3-ACYLINDOLE IMIDAZOPYRIDINE PLATELET-ACTIVATING-FACTOR ANTAGONISTS, Journal of medicinal chemistry, 41(1), 1998, pp. 74-95
DISPOSITION AND EXCRETION OF [H-3] 19-NOR-1-ALPHA,25-DIHYDROXYVITAMIND-2 IN HUMANS
Authors: LEE RD GRABOWSKI B JOHNSON MK DENISSEN JF
Citation: Rd. Lee et al., DISPOSITION AND EXCRETION OF [H-3] 19-NOR-1-ALPHA,25-DIHYDROXYVITAMIND-2 IN HUMANS, Journal of bone and mineral research, 12, 1997, pp. 402-402
METABOLISM AND DISPOSITION OF THE HIV-1 PROTEASE INHIBITOR RITONAVIR (ABT-538) IN RATS, DOGS, AND HUMANS
Authors: DENISSEN JF GRABOWSKI BA JOHNSON MK BUKO AM KEMPF DJ THOMAS SB SURBER BW
Citation: Jf. Denissen et al., METABOLISM AND DISPOSITION OF THE HIV-1 PROTEASE INHIBITOR RITONAVIR (ABT-538) IN RATS, DOGS, AND HUMANS, Drug metabolism and disposition, 25(4), 1997, pp. 489-501
PHARMACOKINETIC ENHANCEMENT OF INHIBITORS OF THE HUMAN-IMMUNODEFICIENCY-VIRUS PROTEASE BY COADMINISTRATION WITH RITONAVIR
Authors: KEMPF DJ MARSH KC KUMAR G RODRIGUES AD DENISSEN JF MCDONALD E KUKULKA MJ HSU A GRANNEMAN GR BAROLDI PA SUN E PIZZUTI D PLATTNER JJ NORBECK DW LEONARD JM
Citation: Dj. Kempf et al., PHARMACOKINETIC ENHANCEMENT OF INHIBITORS OF THE HUMAN-IMMUNODEFICIENCY-VIRUS PROTEASE BY COADMINISTRATION WITH RITONAVIR, Antimicrobial agents and chemotherapy, 41(3), 1997, pp. 654-660
CYTOCHROME P450-MEDIATED METABOLISM OF THE HIV-1 PROTEASE INHIBITOR RITONAVIR (ABT-538) IN HUMAN LIVER-MICROSOMES (VOL 277, PG 423, 1996)
Authors: KUMAR GN RODRIGUES AD BUKO AM DENISSEN JF
Citation: Gn. Kumar et al., CYTOCHROME P450-MEDIATED METABOLISM OF THE HIV-1 PROTEASE INHIBITOR RITONAVIR (ABT-538) IN HUMAN LIVER-MICROSOMES (VOL 277, PG 423, 1996), The Journal of pharmacology and experimental therapeutics, 281(3), 1997, pp. 1506-1506
HEPATIC DRUG-METABOLIZING ACTIVITIES IN RATS AFTER 14 DAYS OF ORAL-ADMINISTRATION OF THE HUMAN IMMUNODEFICIENCY VIRUS-TYPE-1 PROTEASE INHIBITOR RITONAVIR (ABT-538)
Authors: KUMAR GN GRABOWSKI B LEE R DENISSEN JF
Citation: Gn. Kumar et al., HEPATIC DRUG-METABOLIZING ACTIVITIES IN RATS AFTER 14 DAYS OF ORAL-ADMINISTRATION OF THE HUMAN IMMUNODEFICIENCY VIRUS-TYPE-1 PROTEASE INHIBITOR RITONAVIR (ABT-538), Drug metabolism and disposition, 24(5), 1996, pp. 615-617
CYTOCHROME P450-MEDIATED METABOLISM OF THE HIV-1 PROTEASE INHIBITOR RITONAVIR (ABT-538) IN HUMAN LIVER-MICROSOMES
Authors: KUMAR GN RODRIGUES AD BUKO AM DENISSEN JF
Citation: Gn. Kumar et al., CYTOCHROME P450-MEDIATED METABOLISM OF THE HIV-1 PROTEASE INHIBITOR RITONAVIR (ABT-538) IN HUMAN LIVER-MICROSOMES, The Journal of pharmacology and experimental therapeutics, 277(1), 1996, pp. 423-431
A NOVEL, PICOMOLAR INHIBITOR OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 PROTEASES
Authors: SHAM HL ZHAO C STEWART KD BETEBENNER DA LIN SQ PARK CH KONG XP ROSENBROOK W HERRIN T MADIGAN D VASAVANONDA S LYONS N MOLLA A SALDIVAR A MARSH KC MCDONALD E WIDEBURG NE DENISSEN JF ROBINS T KEMPF DJ PLATTNER JJ NORBECK DW
Citation: Hl. Sham et al., A NOVEL, PICOMOLAR INHIBITOR OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 PROTEASES, Journal of medicinal chemistry, 39(2), 1996, pp. 392-397
ABT-538 IS A POTENT INHIBITOR OF HUMAN-IMMUNODEFICIENCY-VIRUS PROTEASE AND HAS HIGH ORAL BIOAVAILABILITY IN HUMANS
Authors: KEMPF DJ MARSH KC DENISSEN JF MCDONALD E VASAVANONDA S FLENTGE CA GREEN BE FINO L PARK CH KONG XP WIDEBURG NE SALDIVAR A RUIZ L KATI WM SHAM HL ROBINS T STEWART KD HSU A PLATTNER JJ LEONARD JM NORBECK DW
Citation: Dj. Kempf et al., ABT-538 IS A POTENT INHIBITOR OF HUMAN-IMMUNODEFICIENCY-VIRUS PROTEASE AND HAS HIGH ORAL BIOAVAILABILITY IN HUMANS, Proceedings of the National Academy of Sciences of the United Statesof America, 92(7), 1995, pp. 2484-2488
THE ORALLY-ACTIVE RENIN INHIBITOR A-74273 - IN-VIVO AND IN-VITRO MORPHOLINE RING METABOLISM IN RATS, DOGS, AND HUMANS
Authors: DENISSEN JF GRABOWSKI BA JOHNSON MK BOYD SA UCHIC JT STEIN H CEPA S HILL P
Citation: Jf. Denissen et al., THE ORALLY-ACTIVE RENIN INHIBITOR A-74273 - IN-VIVO AND IN-VITRO MORPHOLINE RING METABOLISM IN RATS, DOGS, AND HUMANS, Drug metabolism and disposition, 22(6), 1994, pp. 880-888
NONPEPTIDE RENIN INHIBITORS WITH GOOD INTRADUODENAL BIOAVAILABILITY AND EFFICACY IN DOG
Authors: BOYD SA FUNG AKL BAKER WR MANTEI RA STEIN HH COHEN J BARLOW JL KLINGHOFER V WESSALE JL VERBURG KM POLAKOWSKI JS ADLER AL CALZADILLA SV KOVAR P YAO ZL HUTCHINS CW DENISSEN JF GRABOWSKI BA CEPA S HOFFMAN DJ GARREN KW KLEINERT HD
Citation: Sa. Boyd et al., NONPEPTIDE RENIN INHIBITORS WITH GOOD INTRADUODENAL BIOAVAILABILITY AND EFFICACY IN DOG, Journal of medicinal chemistry, 37(19), 1994, pp. 2991-3007
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