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Results: 1-15 |

Results: 15

N-ARYLALKYL PSEUDOPEPTIDE INHIBITORS OF FARNESYLTRANSFERASE

Authors: DESOLMS SJ GIULIANI EA GRAHAM SL KOBLAN KS KOHL NE MOSSER SD OLIFF AI POMPLIANO DL RANDS E SCHOLZ TH WISCOUNT CM GIBBS JB SMITH RL

Citation: Sj. Desolms et al., N-ARYLALKYL PSEUDOPEPTIDE INHIBITORS OF FARNESYLTRANSFERASE, Journal of medicinal chemistry, 41(14), 1998, pp. 2651-2656

ANTITUMOR ACTIVITIES OF FARNESYLTRANSFERASE INHIBITORS

Authors: KOHL NE ANTHONY NJ CONNER MW DESOLMS SJ GIBBS JB GRAHAM L HARTMAN GD KOBLAN KS OMER CA PELLICER A WILLIAMS TM WINDLE JJ OLIFF A

Citation: Ne. Kohl et al., ANTITUMOR ACTIVITIES OF FARNESYLTRANSFERASE INHIBITORS, The FASEB journal, 11(9), 1997, pp. 797-797

MUTATIONAL ANALYSIS OF CONSERVED RESIDUES OF THE BETA-SUBUNIT OF HUMAN FARNESYL-PROTEIN TRANSFERASE

Authors: KRAL AM DIEHL RE DESOLMS SJ WILLIAMS TM KOHL NE OMER CA

Citation: Am. Kral et al., MUTATIONAL ANALYSIS OF CONSERVED RESIDUES OF THE BETA-SUBUNIT OF HUMAN FARNESYL-PROTEIN TRANSFERASE, The Journal of biological chemistry, 272(43), 1997, pp. 27319-27323

FARNESYLTRANSFERASE INHIBITORS - A NEW CLASS OF CANCER CHEMOTHERAPEUTICS

Authors: KOBLAN KS KOHL NE OMER CA ANTHONY NJ CONNER MW DESOLMS SJ WILLIAMS TM GRAHAM SL HARTMAN GD OLIFF A GIBBS JB

Citation: Ks. Koblan et al., FARNESYLTRANSFERASE INHIBITORS - A NEW CLASS OF CANCER CHEMOTHERAPEUTICS, Biochemical Society transactions, 24(3), 1996, pp. 688-692

FARNESYLTRANSFERASE INHIBITORS AND ANTI-RAS THERAPY

Authors: GIBBS JB KOHL NE KOBLAN KS OMER CA SEPPLORENZINO L ROSEN N ANTHONY NJ CONNER MW DESOLMS SJ WILLIAMS TM GRAHAM SL HARTMAN GD OLIFF A

Citation: Jb. Gibbs et al., FARNESYLTRANSFERASE INHIBITORS AND ANTI-RAS THERAPY, Breast cancer research and treatment, 38(1), 1996, pp. 75-83

A-PRIORI PREDICTION OF ACTIVITY FOR HIV-1 PROTEASE INHIBITORS EMPLOYING ENERGY MINIMIZATION IN THE ACTIVE-SITE (VOL 38, PG 308, 1995)

Authors: HOLLOWAY MK WAI JM HALGREN TA FITZGERALD PMD VACCA JP DORSEY BD LEVIN RB THOMPSON WJ CHEN LJ DESOLMS SJ GAFFIN N GHOSH AK GIULIANI EA GRAHAM SL GUARE JP HUNGATE RW LYLE TA SANDERS WM TUCKER TJ WIGGINS M WISCOUNT CM WOLTERSDORF OW YOUNG SD DARKE PL ZUGAY JA

Citation: Mk. Holloway et al., A-PRIORI PREDICTION OF ACTIVITY FOR HIV-1 PROTEASE INHIBITORS EMPLOYING ENERGY MINIMIZATION IN THE ACTIVE-SITE (VOL 38, PG 308, 1995), Journal of medicinal chemistry, 39(11), 1996, pp. 2280-2280

INHIBITION OF FARNESYLTRANSFERASE INDUCES REGRESSION OF MAMMARY AND SALIVARY CARCINOMAS IN RAS TRANSGENIC MICE

Authors: KOHL NE OMER CA CONNER MW ANTHONY NJ DAVIDE JP DESOLMS SJ GIULIANI EA GOMEZ RP GRAHAM SL HAMILTON K HANDT LK HARTMAN GD KOBLAN KS KRAL AM MILLER PJ MOSSER SD ONEILL TJ RANDS E SCHABER MD GIBBS JB OLIFF A

Citation: Ne. Kohl et al., INHIBITION OF FARNESYLTRANSFERASE INDUCES REGRESSION OF MAMMARY AND SALIVARY CARCINOMAS IN RAS TRANSGENIC MICE, Nature medicine, 1(8), 1995, pp. 792-797

NMR-STUDIES OF NOVEL INHIBITORS BOUND TO FARNESYL-PROTEIN TRANSFERASE

Authors: KOBLAN KS CULBERSON JC DESOLMS SJ GIULIANI EA MOSSER SD OMER CA PITZENBERGER SM BOGUSKY MJ

Citation: Ks. Koblan et al., NMR-STUDIES OF NOVEL INHIBITORS BOUND TO FARNESYL-PROTEIN TRANSFERASE, Protein science, 4(4), 1995, pp. 681-688

PSEUDODIPEPTIDE INHIBITORS OF PROTEIN FARNESYLTRANSFERASE

Authors: DESOLMS SJ DEANA AA GIULIANI EA GRAHAM SL KOHL NE MOSSER SD OLIFF AI POMPLIANO DL RANDS E SCHOLZ TH WIGGINS JM GIBBS JB SMITH RL

Citation: Sj. Desolms et al., PSEUDODIPEPTIDE INHIBITORS OF PROTEIN FARNESYLTRANSFERASE, Journal of medicinal chemistry, 38(20), 1995, pp. 3967-3971

A-PRIORI PREDICTION OF ACTIVITY FOR HIV-1 PROTEASE INHIBITORS EMPLOYING ENERGY MINIMIZATION IN THE ACTIVE-SITE

Citation: Mk. Holloway et al., A-PRIORI PREDICTION OF ACTIVITY FOR HIV-1 PROTEASE INHIBITORS EMPLOYING ENERGY MINIMIZATION IN THE ACTIVE-SITE, Journal of medicinal chemistry, 38(2), 1995, pp. 305-317

FARNESYLTRANSFERASE INHIBITION CAUSES MORPHOLOGICAL REVERSION OF RAS-TRANSFORMED CELLS BY A COMPLEX MECHANISM THAT INVOLVES REGULATION OF THE ACTIN CYTOSKELETON

Authors: PRENDERGAST GC DAVIDE JP DESOLMS SJ GIULIANI EA GRAHAM SL GIBBS JB OLIFF A KOHL NE

Citation: Gc. Prendergast et al., FARNESYLTRANSFERASE INHIBITION CAUSES MORPHOLOGICAL REVERSION OF RAS-TRANSFORMED CELLS BY A COMPLEX MECHANISM THAT INVOLVES REGULATION OF THE ACTIN CYTOSKELETON, Molecular and cellular biology, 14(6), 1994, pp. 4193-4202

PROTEIN FARNESYLTRANSFERASE INHIBITORS BLOCK THE GROWTH OF RAS-DEPENDENT TUMORS IN NUDE-MICE

Authors: KOHL NE WILSON FR MOSSER SD GIULIANI E DESOLMS SJ CONNER MW ANTHONY NJ HOLTZ WJ GOMEZ RP LEE TJ SMITH RL GRAHAM SL HARTMAN GD GIBBS JB OLIFF A

Citation: Ne. Kohl et al., PROTEIN FARNESYLTRANSFERASE INHIBITORS BLOCK THE GROWTH OF RAS-DEPENDENT TUMORS IN NUDE-MICE, Proceedings of the National Academy of Sciences of the United Statesof America, 91(19), 1994, pp. 9141-9145

PSEUDOPEPTIDE INHIBITORS OF RAS FARNESYL-PROTEIN TRANSFERASE

Authors: GRAHAM SL DESOLMS SJ GIULIANI EA KOHL NE MOSSER SD OLIFF AI POMPLIANO DL RANDS E BRESLIN MJ DEANA AA GARSKY VM SCHOLZ TH GIBBS JB SMITH RL

Citation: Sl. Graham et al., PSEUDOPEPTIDE INHIBITORS OF RAS FARNESYL-PROTEIN TRANSFERASE, Journal of medicinal chemistry, 37(6), 1994, pp. 725-732

SELECTIVE-INHIBITION OF RAS-DEPENDENT CELL-TRANSFORMATION BY A FARNESYL-PROTEIN TRANSFERASE INHIBITOR

Authors: GIBBS JB KOHL NE POMPLIANO DL MOSSER SD SINGH SB ANTHONY NJ GOMEZ RP DESOLMS SJ GIULIANI E GRAHAM SL SMITH RL OLIFF A

Citation: Jb. Gibbs et al., SELECTIVE-INHIBITION OF RAS-DEPENDENT CELL-TRANSFORMATION BY A FARNESYL-PROTEIN TRANSFERASE INHIBITOR, The FASEB journal, 7(7), 1993, pp. 1048-1048

SELECTIVE-INHIBITION OF RAS-DEPENDENT TRANSFORMATION BY A FARNESYLTRANSFERASE INHIBITOR

Authors: KOHL NE MOSSER SD DESOLMS SJ GIULIANI EA POMPLIANO DL GRAHAM SL SMITH RL SCOLNICK EM OLIFF A GIBBS JB

Citation: Ne. Kohl et al., SELECTIVE-INHIBITION OF RAS-DEPENDENT TRANSFORMATION BY A FARNESYLTRANSFERASE INHIBITOR, Science, 260(5116), 1993, pp. 1934-1937

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