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Results: 1-9 |
Results: 9
INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE - 4-AMIDO, 4-CARBAMOYL, AND 4-CARBOXAMIDO DERIVATIVES OF ENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YL)PIPERAZINE AND ENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YL)PIPERAZINE
Authors: MALLAMS AK ROSSMAN RR DOLL RJ GIRIJAVALLABHAN VM GANGULY AK PETRIN J WANG L PATTON R BISHOP WR CARR DM KIRSCHMEIER P CATINO JJ BRYANT MS CHEN KJ KORFMACHER WA NARDO C WANG SY NOMEIR AA LIN CC LI ZJ CHEN JP LEE S DELL J LIPARI P MALKOWSKI M YAREMKO B KING I LIU M
Citation: Ak. Mallams et al., INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE - 4-AMIDO, 4-CARBAMOYL, AND 4-CARBOXAMIDO DERIVATIVES OF ENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YL)PIPERAZINE AND ENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YL)PIPERAZINE, Journal of medicinal chemistry, 41(6), 1998, pp. 877-893
-PIPERIDINYL]-2-OXO-ETHYL]-1-PIPERIDINECARBOXAMIDE (SCH-66336) - A VERY POTENT FARNESYL-PROTEIN TRANSFERASE INHIBITOR AS A NOVEL ANTITUMOR AGENT())
Authors: NJOROGE FG TAVERAS AG KELLY J REMISZEWSKI S MALLAMS AK WOLIN R AFONSO A COOPER AB RANE DF LIU YT WONG J VIBULBHAN B PINTO P DESKUS J ALVAREZ CS DELROSARIO J CONNOLLY M WANG J DESAI J ROSSMAN RR BISHOP WR PATTON R WANG L KIRSCHMEIER P BRYANT MS NOMEIR AA LIN CC LIU M MCPHAIL AT DOLL RJ GIRIJAVALLABHAN VM GANGULY AK
Citation: Fg. Njoroge et al., -PIPERIDINYL]-2-OXO-ETHYL]-1-PIPERIDINECARBOXAMIDE (SCH-66336) - A VERY POTENT FARNESYL-PROTEIN TRANSFERASE INHIBITOR AS A NOVEL ANTITUMOR AGENT()), Journal of medicinal chemistry, 41(24), 1998, pp. 4890-4902
POTENT, SELECTIVE, AND ORALLY BIOAVAILABLE TRICYCLIC PYRIDYL ACETAMIDE N-OXIDE INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE WITH ENHANCED IN-VIVO ANTITUMOR-ACTIVITY
Authors: NJOROGE FG VIBULBHAN B PINTO P BISHOP WR BRYANT MS NOMEIR AA LIN CC LIU M DOLL RJ GIRIJAVALLABHAN V GANGULY AK
Citation: Fg. Njoroge et al., POTENT, SELECTIVE, AND ORALLY BIOAVAILABLE TRICYCLIC PYRIDYL ACETAMIDE N-OXIDE INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE WITH ENHANCED IN-VIVO ANTITUMOR-ACTIVITY, Journal of medicinal chemistry, 41(10), 1998, pp. 1561-1567
ANTITUMOR-ACTIVITY OF SCH-66336, AN ORALLY BIOAVAILABLE TRICYCLIC INHIBITOR OF FARNESYL-PROTEIN TRANSFERASE, IN HUMAN TUMOR XENOGRAFT MODELS AND WAP-RAS TRANSGENIC MICE
Authors: LIU M BRYANT MS CHEN JP LEE SN YAREMKO B LIPARI P MALKOWSKI M FERRARI E NIELSEN L PRIOLI N DELL J SINHA D SYED J KORFMACHER WA NOMEIR AA LIN CC WANG L TAVERAS AG DOLL RJ NJOROGE FG MALLAMS AK REMISZEWSKI S CATINO JJ GIRIJAVALLABHAN VM KIRSCHMEIER P BISHOP WR
Citation: M. Liu et al., ANTITUMOR-ACTIVITY OF SCH-66336, AN ORALLY BIOAVAILABLE TRICYCLIC INHIBITOR OF FARNESYL-PROTEIN TRANSFERASE, IN HUMAN TUMOR XENOGRAFT MODELS AND WAP-RAS TRANSGENIC MICE, Cancer research, 58(21), 1998, pp. 4947-4956
INTERACTION OF A NOVEL GDP EXCHANGE INHIBITOR WITH THE RAS PROTEIN
Authors: GANGULY AK WANG YS PRAMANIK BN DOLL RJ SNOW ME TAVERAS AG REMISZEWSKI S CESARZ D DELROSARIO J VIBULBHAN B BROWN JE KIRSCHMEIER P HUANG EC HEIMARK L TSARBOPOULOS A GIRIJAVALLABHAN VM AUST RM BROWN EL DELISLE DM FUHRMAN SA HENDRICKSON TF KISSINGER CR LOVE RA SISSON WA VILLAFRANCA JE WEBBER SE
Citation: Ak. Ganguly et al., INTERACTION OF A NOVEL GDP EXCHANGE INHIBITOR WITH THE RAS PROTEIN, Biochemistry (Easton), 37(45), 1998, pp. 15631-15637
DETECTION AND STRUCTURAL CHARACTERIZATION OF RAS ONCOPROTEIN-INHIBITORS COMPLEXES BY ELECTROSPRAY MASS-SPECTROMETRY
Authors: GANGULY AK PRAMANIK BN HUANG EC LIBERLES S HEIMARK L LIU YH TSARBOPOULOS A DOLL RJ TAVERAS AG REMISZEWSKI S SNOW ME WANG YS VIBULBHAN B CESARZ D BROWN JE DELROSARIO J KIRSCHMEIER P GIRIJAVALLABHAN V
Citation: Ak. Ganguly et al., DETECTION AND STRUCTURAL CHARACTERIZATION OF RAS ONCOPROTEIN-INHIBITORS COMPLEXES BY ELECTROSPRAY MASS-SPECTROMETRY, Bioorganic & medicinal chemistry, 5(5), 1997, pp. 817-820
STRUCTURE-ACTIVITY RELATIONSHIP OF 3-SUBSTITUTED ,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YLIDENE)-PIPERIDINE INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE - DESIGN AND SYNTHESIS OF IN-VIVO ACTIVE ANTITUMOR COMPOUNDS
Authors: NJOROGE FG VIBULBHAN B RANE DF BISHOP WR PETRIN J PATTON R BRYANT MS CHEN KJ NOMEIR AA LIN CC LIU M KING I CHEN JP LEE SN YAREMKO B DELL J LIPARI P MALKOWSKI M LI ZJ CATINO J DOLL RJ GIRIJAVALLABHAN V GANGULY AK
Citation: Fg. Njoroge et al., STRUCTURE-ACTIVITY RELATIONSHIP OF 3-SUBSTITUTED ,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YLIDENE)-PIPERIDINE INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE - DESIGN AND SYNTHESIS OF IN-VIVO ACTIVE ANTITUMOR COMPOUNDS, Journal of medicinal chemistry, 40(26), 1997, pp. 4290-4301
NOVEL TRICYCLIC AMINOACETYL AND SULFONAMIDE INHIBITORS OF RAS FARNESYL-PROTEIN TRANSFERASE
Authors: NJOROGE FG VIBULBHAN B ALVAREZ CS BISHOP WR PETRIN J DOLL RJ GIRIJAVALLABHAN V GANGULY AK
Citation: Fg. Njoroge et al., NOVEL TRICYCLIC AMINOACETYL AND SULFONAMIDE INHIBITORS OF RAS FARNESYL-PROTEIN TRANSFERASE, Bioorganic & medicinal chemistry letters, 6(24), 1996, pp. 2977-2982
SYNTHESIS AND PHOSPHODIESTERASE ACTIVITY OF CARBOXYLIC-ACID MIMETICS OF CYCLIC GUANOSINE 3',5'-MONOPHOSPHATE
Authors: TUSHIAN D CZARNIECKI M DOLL RJ AHN HS
Citation: D. Tushian et al., SYNTHESIS AND PHOSPHODIESTERASE ACTIVITY OF CARBOXYLIC-ACID MIMETICS OF CYCLIC GUANOSINE 3',5'-MONOPHOSPHATE, Journal of medicinal chemistry, 36(9), 1993, pp. 1210-1220
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