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Results: 1-21 |
Results: 21
A NEW SYNTHETIC APPROACH TO THE CLINICALLY USEFUL, ANTI-HIV-ACTIVE NUCLEOSIDE, DEOXY-2-FLUORO-BETA-D-THREO-PENTOFURANOSYL)ADENINE (BETA-FDDA) - INTRODUCTION OF A 2'-BETA-FLUORO SUBSTITUENT VIA INVERSION OF A READILY OBTAINABLE 2'-ALPHA-FLUORO ISOMER
Authors: SIDDIQUI MA DRISCOLL JS MARQUEZ VE
Citation: Ma. Siddiqui et al., A NEW SYNTHETIC APPROACH TO THE CLINICALLY USEFUL, ANTI-HIV-ACTIVE NUCLEOSIDE, DEOXY-2-FLUORO-BETA-D-THREO-PENTOFURANOSYL)ADENINE (BETA-FDDA) - INTRODUCTION OF A 2'-BETA-FLUORO SUBSTITUENT VIA INVERSION OF A READILY OBTAINABLE 2'-ALPHA-FLUORO ISOMER, Tetrahedron letters, 39(13), 1998, pp. 1657-1660
2'-FLUORO-2',3'-DIDEOXYARABINOSYLADENINE (F-DDA) - ACTIVITY AGAINST DRUG-RESISTANT HUMAN-IMMUNODEFICIENCY-VIRUS STRAINS AND CLADES A-E
Authors: DRISCOLL JS MAYERS DL BADER JP WEISLOW OS JOHNS DG BUCKHEIT RW
Citation: Js. Driscoll et al., 2'-FLUORO-2',3'-DIDEOXYARABINOSYLADENINE (F-DDA) - ACTIVITY AGAINST DRUG-RESISTANT HUMAN-IMMUNODEFICIENCY-VIRUS STRAINS AND CLADES A-E, Antiviral chemistry & chemotherapy, 8(2), 1997, pp. 107-111
DECAY-RATES OF ANTI-HIV DIDEOXYNUCLEOTIDES IN TISSUE-CULTURE SYSTEMS - A SIMPLE CORRECTION FOR THE EFFECT OF CELL REPLICATION
Authors: AHLUWALIA GS DEDRICK RL DRISCOLL JS MORRISON PF GAO WY JOHNS DG
Citation: Gs. Ahluwalia et al., DECAY-RATES OF ANTI-HIV DIDEOXYNUCLEOTIDES IN TISSUE-CULTURE SYSTEMS - A SIMPLE CORRECTION FOR THE EFFECT OF CELL REPLICATION, Drug metabolism and disposition, 25(7), 1997, pp. 893-896
IN-VITRO INDUCTION OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 VARIANTS RESISTANT TO 2'-BETA-FLUORO-2',3'-DIDEOXYADENOSINE
Authors: TANAKA M SRINIVAS RV UENO T KAVLICK MF HUI FK FRIDLAND A DRISCOLL JS MITSUYA H
Citation: M. Tanaka et al., IN-VITRO INDUCTION OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 VARIANTS RESISTANT TO 2'-BETA-FLUORO-2',3'-DIDEOXYADENOSINE, Antimicrobial agents and chemotherapy, 41(6), 1997, pp. 1313-1318
POTENT ACTIVITY OF 2'-BETA-FLUORO-2',3'-DIDEOXYADENOSINE AGAINST HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 INFECTION IN HU-PBL-SCID MICE
Authors: RUXRUNGTHAM K BOONE E FORD H DRISCOLL JS DAVEY RT LANE HC
Citation: K. Ruxrungtham et al., POTENT ACTIVITY OF 2'-BETA-FLUORO-2',3'-DIDEOXYADENOSINE AGAINST HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 INFECTION IN HU-PBL-SCID MICE, Antimicrobial agents and chemotherapy, 40(10), 1996, pp. 2369-2374
COMPARISON OF THE DNA INCORPORATION IN HUMAN MOLT-4 CELLS OF 2 2'-BETA-FLUORONUCLEOSIDES, 2'-BETA-FLUORO-2',3'-DIDEOXYADENOSINE AND FIALURIDINE
Authors: AHLUWALIA GS DRISCOLL JS FORD H JOHNS DG
Citation: Gs. Ahluwalia et al., COMPARISON OF THE DNA INCORPORATION IN HUMAN MOLT-4 CELLS OF 2 2'-BETA-FLUORONUCLEOSIDES, 2'-BETA-FLUORO-2',3'-DIDEOXYADENOSINE AND FIALURIDINE, Journal of pharmaceutical sciences, 85(4), 1996, pp. 454-455
LIPOPHILIC, ACID-STABLE, ADENOSINE DEAMINASE-ACTIVATED ANTI-HIV PRODRUGS FOR CENTRAL-NERVOUS-SYSTEM DELIVERY .3. 6-AMINO PRODRUGS OF 2'-BETA-FLUORO-2',3'-DIDEOXYINOSINE
Authors: DRISCOLL JS SIDDIQUI MA FORD H KELLEY JA ROTH JS MITSUYA H TANAKA M MARQUEZ VE
Citation: Js. Driscoll et al., LIPOPHILIC, ACID-STABLE, ADENOSINE DEAMINASE-ACTIVATED ANTI-HIV PRODRUGS FOR CENTRAL-NERVOUS-SYSTEM DELIVERY .3. 6-AMINO PRODRUGS OF 2'-BETA-FLUORO-2',3'-DIDEOXYINOSINE, Journal of medicinal chemistry, 39(8), 1996, pp. 1619-1625
ACUTE CARDIOTOXICITY OF THE ANTI-HIV DIDEOXYNUCLEOSIDE, F-DDA, IN THERAT
Authors: DONZANTI BA KELLEY JA TOMASZEWSKI JE ROTH JS TOSCA P PLACKE M SINGER A YARRINGTON JT DRISCOLL JS
Citation: Ba. Donzanti et al., ACUTE CARDIOTOXICITY OF THE ANTI-HIV DIDEOXYNUCLEOSIDE, F-DDA, IN THERAT, Fundamental and applied toxicology, 27(2), 1995, pp. 167-176
LIPOPHILIC, ACID-STABLE, ADENOSINE DEAMINASE-ACTIVATED ANTI-HIV PRODRUGS FOR CENTRAL-NERVOUS-SYSTEM DELIVERY .2. 6-HALO AND 6-ALKOXY PRODRUGS OF 2'-BETA-FLUORO-2',3'-DIDEOXYINOSINE
Authors: FORD H SIDDIQUI MA DRISCOLL JS MARQUEZ VE KELLEY JA MITSUYA H SHIRASAKA T
Citation: H. Ford et al., LIPOPHILIC, ACID-STABLE, ADENOSINE DEAMINASE-ACTIVATED ANTI-HIV PRODRUGS FOR CENTRAL-NERVOUS-SYSTEM DELIVERY .2. 6-HALO AND 6-ALKOXY PRODRUGS OF 2'-BETA-FLUORO-2',3'-DIDEOXYINOSINE, Journal of medicinal chemistry, 38(7), 1995, pp. 1189-1195
ENHANCEMENT BY HYDROXYUREA OF THE ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 POTENCY OF 2'-BETA-FLUORO-2',3'-DIDEOXYADENOSINE IN PERIPHERAL-BLOOD MONONUCLEAR CELLS
Authors: GAO WY MITSUYA H DRISCOLL JS JOHNS DG
Citation: Wy. Gao et al., ENHANCEMENT BY HYDROXYUREA OF THE ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 POTENCY OF 2'-BETA-FLUORO-2',3'-DIDEOXYADENOSINE IN PERIPHERAL-BLOOD MONONUCLEAR CELLS, Biochemical pharmacology, 50(2), 1995, pp. 274-276
REVERSAL BY CYTIDINE OF CYCLOPENTENYL CYTOSINE-INDUCED TOXICITY IN MICE WITHOUT COMPROMISE OF ANTITUMOR-ACTIVITY
Authors: FORD H DRISCOLL JS HAO Z DOBYNS KA ROMMEL ME STOWE E ANDERSON JO PLOWMAN J WAUD WR JOHNS DG COONEY DA
Citation: H. Ford et al., REVERSAL BY CYTIDINE OF CYCLOPENTENYL CYTOSINE-INDUCED TOXICITY IN MICE WITHOUT COMPROMISE OF ANTITUMOR-ACTIVITY, Biochemical pharmacology, 49(2), 1995, pp. 173-180
THE DESIGN AND SYNTHESIS OF A NEW ANTICANCER DRUG BASED ON A NATURAL PRODUCT LEAD COMPOUND - FROM NEPLANOCIN-A TO CYCLOPENTENYL CYTOSINE (CPE-C)
Authors: DRISCOLL JS MARQUEZ VE
Citation: Js. Driscoll et Ve. Marquez, THE DESIGN AND SYNTHESIS OF A NEW ANTICANCER DRUG BASED ON A NATURAL PRODUCT LEAD COMPOUND - FROM NEPLANOCIN-A TO CYCLOPENTENYL CYTOSINE (CPE-C), Stem cells, 12(1), 1994, pp. 7-12
CHEMISTRY AND ANTI-HIV ACTIVITY OF 2'-BETA-FLUORO-2',3'-DIDEOXYGUANOSINE
Authors: FORD H DRISCOLL JS SIDDIQUI M KELLEY JA MITSUYA H SHIRASAKA T JOHNS DG MARQUEZ VE
Citation: H. Ford et al., CHEMISTRY AND ANTI-HIV ACTIVITY OF 2'-BETA-FLUORO-2',3'-DIDEOXYGUANOSINE, Nucleosides & nucleotides, 13(1-3), 1994, pp. 213-234
NATIONAL-CANCER-INSTITUTE DRUG INFORMATION-SYSTEM 3D DATABASE
Authors: MILNE GWA NICKLAUS MC DRISCOLL JS WANG SM ZAHAREVITZ D
Citation: Gwa. Milne et al., NATIONAL-CANCER-INSTITUTE DRUG INFORMATION-SYSTEM 3D DATABASE, Journal of chemical information and computer sciences, 34(5), 1994, pp. 1219-1224
A DIASTEREOSELECTIVE SYNTHESIS OF LPHA-FLUORO-2,2-DIMETHYL-1,3-DIOXOLANE-4-PROPANOIC ACID METHYL-ESTER, A KEY INTERMEDIATE FOR THE PREPARATION OF ANTI-HIV EFFECTIVE FLUORODIDEOXYNUCLEOSIDES
Authors: SIDDIQUI MA MARQUEZ VE DRISCOLL JS BARCHI JJ
Citation: Ma. Siddiqui et al., A DIASTEREOSELECTIVE SYNTHESIS OF LPHA-FLUORO-2,2-DIMETHYL-1,3-DIOXOLANE-4-PROPANOIC ACID METHYL-ESTER, A KEY INTERMEDIATE FOR THE PREPARATION OF ANTI-HIV EFFECTIVE FLUORODIDEOXYNUCLEOSIDES, Tetrahedron letters, 35(20), 1994, pp. 3263-3266
ENHANCEMENT BY 2'-DEOXYCOFORMYCIN OF THE 5'-PHOSPHORYLATION AND ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS ACTIVITY OF 2',3'-DIDEOXYADENOSINE AND 2'-BETA-FLUORO-2',3'-DIDEOXYADENOSINE
Authors: AHLUWALIA GS COONEY DA SHIRASAKA T MITSUYA H DRISCOLL JS JOHNS DG
Citation: Gs. Ahluwalia et al., ENHANCEMENT BY 2'-DEOXYCOFORMYCIN OF THE 5'-PHOSPHORYLATION AND ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS ACTIVITY OF 2',3'-DIDEOXYADENOSINE AND 2'-BETA-FLUORO-2',3'-DIDEOXYADENOSINE, Molecular pharmacology, 46(5), 1994, pp. 1002-1008
DIVERGENT ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS ACTIVITY AND ANABOLIC PHOSPHORYLATION OF 2',3'-DIDEOXYNUCLEOSIDE ANALOGS IN RESTING AND ACTIVATED HUMAN-CELLS
Authors: GAO WY AGBARIA R DRISCOLL JS MITSUYA H
Citation: Wy. Gao et al., DIVERGENT ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS ACTIVITY AND ANABOLIC PHOSPHORYLATION OF 2',3'-DIDEOXYNUCLEOSIDE ANALOGS IN RESTING AND ACTIVATED HUMAN-CELLS, The Journal of biological chemistry, 269(17), 1994, pp. 12633-12638
EFFECT OF ANTI-HIV 2'-BETA-FLUORO-2',3'-DIDEOXYNUCLEOSIDE ANALOGS ON THE CELLULAR CONTENT OF MITOCHONDRIAL-DNA AND ON LACTATE PRODUCTION
Authors: TSAI CH DOONG SL JOHNS DG DRISCOLL JS CHENG YC
Citation: Ch. Tsai et al., EFFECT OF ANTI-HIV 2'-BETA-FLUORO-2',3'-DIDEOXYNUCLEOSIDE ANALOGS ON THE CELLULAR CONTENT OF MITOCHONDRIAL-DNA AND ON LACTATE PRODUCTION, Biochemical pharmacology, 48(7), 1994, pp. 1477-1481
ENHANCED STIMULATION BY RIBAVIRIN OF THE 5'-PHOSPHORYLATION AND ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS ACTIVITY OF PURINE 2'-BETA-FLUORO-2',3'-DIDEOXYNUCLEOSIDES
Authors: JOHNS DG AHLUWALIA GS COONEY DA MITSUYA H DRISCOLL JS
Citation: Dg. Johns et al., ENHANCED STIMULATION BY RIBAVIRIN OF THE 5'-PHOSPHORYLATION AND ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS ACTIVITY OF PURINE 2'-BETA-FLUORO-2',3'-DIDEOXYNUCLEOSIDES, Molecular pharmacology, 44(3), 1993, pp. 519-523
SYNTHESIS OF CARBOCYCLIC ANALOGS OF 1-BETA-D-PSICOFURANOSYL NUCLEOSIDES - PSICO-CYCLOPENTENYLADENOSINE (PSICOPLANOCIN-A) AND PSICO-CYCLOPENTENYLCYTOSINE
Authors: BODENTEICH M MARQUEZ VE BARCHI JJ HALLOWS WH GOLDSTEIN BM DRISCOLL JS
Citation: M. Bodenteich et al., SYNTHESIS OF CARBOCYCLIC ANALOGS OF 1-BETA-D-PSICOFURANOSYL NUCLEOSIDES - PSICO-CYCLOPENTENYLADENOSINE (PSICOPLANOCIN-A) AND PSICO-CYCLOPENTENYLCYTOSINE, Journal of organic chemistry, 58(22), 1993, pp. 6009-6015
CYCLOPENTENE CARBOCYCLIC NUCLEOSIDES RELATED TO THE ANTITUMOR NUCLEOSIDE CLITOCINE AND THEIR CONVERSION TO 8-AZA-NEPLANOCIN ANALOGS - SYNTHESIS AND ANTIVIRAL ACTIVITY
Authors: MARQUEZ VE LIM BB DRISCOLL JS SNOEK R BALZARINI J IKEDA S ANDREI G DECLERCQ E
Citation: Ve. Marquez et al., CYCLOPENTENE CARBOCYCLIC NUCLEOSIDES RELATED TO THE ANTITUMOR NUCLEOSIDE CLITOCINE AND THEIR CONVERSION TO 8-AZA-NEPLANOCIN ANALOGS - SYNTHESIS AND ANTIVIRAL ACTIVITY, Journal of heterocyclic chemistry, 30(5), 1993, pp. 1393-1398
Risultati: 1-21 |