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Citation: Kp. Zuideveld et al., A set-point model with oscillatory behavior predicts the time course of 8-OH-DPAT-induced hypothermia, AM J P-REG, 281(6), 2001, pp. R2059-R2071
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Citation: P. Vis et al., Population pharmacokinetic-pharmacodynamic modelling of S 15535, a 5-MT1A receptor agonist, using a behavioural model in rats, EUR J PHARM, 414(2-3), 2001, pp. 233-243
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Citation: Tj. Parker et al., Pharmacokinetic-pharmacodynamic modelling in the early development phase of anti-psychotics: A comparison of the effects of clozapine, S 16924 and S 18327 in the EEG model in rats, BR J PHARM, 132(1), 2001, pp. 151-158
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Citation: Sag. Visser et al., High-performance liquid chromatography of the neuroactive steroids alphaxalone and pregnanolone in plasma using dansyl hydrazine as fluorescent label: application to a pharmacokinetic-pharmacodynamic study in rats, J CHROMAT B, 745(2), 2000, pp. 357-363
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Citation: Kp. Zuideveld et al., Enantioselective high-performance liquid chromatographic analysis of the 5-HT1A receptor agonist 8-hydroxy-2(di-n-propylamino)tetralin - Application to a pharmacokinetic-pharmacodynamic study in rats, J CHROMAT B, 738(1), 2000, pp. 67-73
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Citation: A. Cleton et al., Pharmacokinetic-pharmacodynamic modelling of tiagabine CNS effects upon chronic treatment in rats: lack of change in concentration-EEG effect relationship, EUR J PH SC, 12(2), 2000, pp. 141-150
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Citation: Oe. Della Paschoa et al., Pharmacokinetic-pharmacodynamic correlation of lamotrigine, flunarizine, loreclezole, CGP40116 and CGP39551 in the cortical stimulation model, EPILEPSY R, 40(1), 2000, pp. 41-52
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Citation: M. Garrido et al., Pharmacokinetic-pharmacodynamic analysis of the EEG effect of alfentanil in rats following beta-funaltrexamine-induced mu-opioid receptor "knockdown"in vivo, PHARM RES, 17(6), 2000, pp. 653-659
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Citation: A. Cleton et al., Mechanism-based modeling of functional adaptation upon chronic treatment with midazolam, PHARM RES, 17(3), 2000, pp. 321-327
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Citation: Sr. Santos et al., A simple HPLC-fluorescence method for the measurement of R,S-sotalol in the plasma of patients with life-threatening cardiac arrhythmias, BRAZ J MED, 33(2), 2000, pp. 199-204
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Citation: Caj. Knibbe et al., Pharmacokinetics and pharmacodynamics of propofol 6% SAZN versus propofol 1% SAZN and Diprivan-10 for short-term sedation following coronary artery bypass surgery, EUR J CL PH, 56(1), 2000, pp. 89-95
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Citation: A. Cleton et al., Effect of amygdala kindling on the central nervous system effects of tiagabine: EEG effects versus brain GABA levels, BR J PHARM, 130(5), 2000, pp. 1037-1044
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Citation: A. Cleton et al., Mechanism-based modeling of adaptive changes in the pharmacodynamics of midazolam in the kindling model of epilepsy, PHARM RES, 16(11), 1999, pp. 1702-1709
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Citation: Caj. Knibbe et al., Pharmacokinetics, induction of anaesthesia and safety characteristics of propofol 6% SAZN vs propofol 1% SAZN and Diprivan (R)-10 after bolus injection, BR J CL PH, 47(6), 1999, pp. 653-660
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Citation: E. Snoeck et al., A combined specific target site binding and pharmacokinetic model to explore the non-linear disposition of draflazine, J PHAR BIOP, 27(3), 1999, pp. 257-281
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Citation: A. Cleton et al., Application of a combined "effect compartment/indirect response model" to the central nervous system effects of tiagabine in the rat, J PHAR BIOP, 27(3), 1999, pp. 301-323
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Citation: Ph. Van Der Graaf et al., Mechanism-based pharmacokinetic-pharmacodynamic modeling of antilipolytic effects of adenosine A(1) receptor agonists in rats: Prediction of tissue-dependent efficacy in vivo, J PHARM EXP, 290(2), 1999, pp. 702-709
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Citation: B. Tuk et al., Characterization of the pharmacodynamic interaction between parent drug and active metabolite in vivo: Midazolam and alpha-OH-midazolam, J PHARM EXP, 289(2), 1999, pp. 1067-1074
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Citation: Ph. Van Der Graaf et al., Multivariate quantitative structure-pharmacokinetic relationships (QSPKR) analysis of adenosine A(1) receptor agonists in rat, J PHARM SCI, 88(3), 1999, pp. 306-312
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Citation: A. Cleton et al., Stereoselective central nervous system effects of the R- and S-isomers of the GABA uptake blocker N-(4,4-di-(3-methylthien-2-yl)but-3-enyl) nipecoticacid in the rat, BR J PHARM, 128(8), 1999, pp. 1651-1658