Authors:
De Jonghe, C
Esselens, C
Kumar-Singh, S
Craessaerts, K
Serneels, S
Checler, F
Annaert, W
Van Broeckhoven, C
De Strooper, B
Citation: C. De Jonghe et al., Pathogenic APP mutations near the gamma-secretase cleavage site differentially affect A beta secretion and APP C-terminal fragment stability, HUM MOL GEN, 10(16), 2001, pp. 1665-1671
Authors:
Roymans, D
Vissenberg, K
De Jonghe, C
Grobben, B
Claes, P
Verbelen, JP
Van Broeckhoven, C
Slegers, H
Citation: D. Roymans et al., Phosphatidylinositol 3-kinase activity is required for the expression of glial fibrillary acidic protein upon cAMP-dependent induction of differentiation in rat C6 glioma, J NEUROCHEM, 76(2), 2001, pp. 610-618
Authors:
Roymans, D
Vissenberg, K
De Jonghe, C
Willems, R
Engler, G
Kimura, N
Grobben, B
Claes, P
Verbelen, JP
Van Broeckhoven, C
Slegers, H
Citation: D. Roymans et al., Identification of the tumor metastasis suppressor Nm23-H1/Nm23-R1 as a constituent of the centrosome, EXP CELL RE, 262(2), 2001, pp. 145-153
Authors:
Van Gassen, G
De Jonghe, C
Nishimura, M
Yu, G
Kuhn, S
St George-Hyslop, PS
Van Broeckhoven, C
Citation: G. Van Gassen et al., Evidence that the beta-catenin nuclear translocation assay allows for measuring presenilin 1 dysfunction, MOL MED, 6(7), 2000, pp. 570-580
Authors:
Kumar-Singh, S
Dewachter, I
Moechars, D
Lubke, U
De Jonghe, C
Ceuterick, C
Checler, F
Naidu, A
Cordell, B
Cras, P
Van Broeckhoven, C
Van Leuven, F
Citation: S. Kumar-singh et al., Behavioral disturbances without amyloid deposits in mice overexpressing human amyloid precursor protein with Flemish (A692G) or Dutch (E693Q) mutation, NEUROBIOL D, 7(1), 2000, pp. 9-22
Authors:
Kumar-Singh, S
De Jonghe, C
Cruts, M
Kleinert, R
Wang, R
Mercken, M
De Strooper, B
Vanderstichele, H
Lofgren, A
Vanderhoeven, I
Backhovens, H
Vanmechelen, E
Kroisel, PM
Van Broeckhoven, C
Citation: S. Kumar-singh et al., Nonfibrillar diffuse amyloid deposition due to a gamma(42)-secretase site mutation points to an essential role for N-truncated A beta(42) in Alzheimer's disease, HUM MOL GEN, 9(18), 2000, pp. 2589-2598
Authors:
Roymans, D
Willems, R
Vissenberg, K
De Jonghe, C
Grobben, B
Claes, P
Lascu, I
Van Bockstaele, D
Verbelen, JP
Van Broeckhoven, C
Slegers, H
Citation: D. Roymans et al., Nucleoside diphosphate kinase beta (Nm23-R1/NDPK beta) is associated with intermediate filaments and becomes upregulated upon cAMP-induced differentiation of rat C6 glioma, EXP CELL RE, 261(1), 2000, pp. 127-138
Authors:
Singleton, AB
Hall, R
Ballard, CG
Perry, RH
Xuereb, JH
Rubinsztein, DC
Tysoe, C
Matthews, P
Cordell, B
Kumar-Singh, S
De Jonghe, C
Cruts, M
van Broeckhoven, C
Morris, CM
Citation: Ab. Singleton et al., Pathology of early-onset Alzheimer's disease cases bearing the Thr113-114ins presenilin-1 mutation, BRAIN, 123, 2000, pp. 2467-2474
Authors:
Roks, G
Van Harskamp, F
De Koning, I
Cruts, M
De Jonghe, C
Kumar-Singh, S
Tibben, A
Tanghe, H
Niermeijer, MF
Hofman, A
Van Swieten, JC
Van Broeckhoven, C
Van Duijn, CM
Citation: G. Roks et al., Presentation of amyloidosis in carriers of the codon 692 mutation in the amyloid precursor protein gene (APP692), BRAIN, 123, 2000, pp. 2130-2140
Authors:
Van Gassen, G
De Jonghe, C
Pype, S
Van Criekinge, W
Julliams, A
Vanderhoeven, I
Woodrow, S
Beyaert, R
Huylebroeck, D
Van Broeckhoven, C
Citation: G. Van Gassen et al., Alzheimer's disease associated presenilin 1 interacts with HC5 and ZETA, subunits of the catalytic 20S proteasome, NEUROBIOL D, 6(5), 1999, pp. 376-391
Authors:
De Jonghe, C
Cras, P
Vanderstichele, H
Cruts, M
Vanderhoeven, I
Smouts, I
Vanmechelen, E
Martin, JJ
Hendriks, L
Van Broeckhoven, C
Citation: C. De Jonghe et al., Evidence that A beta 42 plasma levels in presenilin-1 mutation carriers donot allow for prediction of their clinical phenotype, NEUROBIOL D, 6(4), 1999, pp. 280-287
Authors:
De Jonghe, C
Cruts, M
Rogaeva, EA
Tysoe, C
Singleton, A
Vanderstichele, H
Meschino, W
Dermaut, D
Vanderhoeven, I
Backhovens, H
Vanmechelen, E
Morris, CM
Hardy, J
Rubinsztein, DC
St George-Hyslop, PH
Van Broeckhoven, C
Citation: C. De Jonghe et al., Aberrant splicing in the presenilin-1 intron 4 mutation causes presenile Alzheimer's disease by increased A beta 42 secretion, HUM MOL GEN, 8(8), 1999, pp. 1529-1540
Authors:
Vanderhoeven, I
Cras, P
Martin, JJ
Van Broeckhoven, C
De Jonghe, C
Citation: I. Vanderhoeven et al., Proteolytic processing of presenilin-1 in human lymphoblasts is not affected by the presence of the I143Tand G384A mutations, NEUROSCI L, 274(3), 1999, pp. 183-186
Authors:
Julliams, A
Vanderhoeven, I
Kuhn, S
Van Broeckhoven, C
De Jonghe, C
Citation: A. Julliams et al., No influence of presenilin 1 I143Tand G384A mutations on endogenous tau phosphorylation in human and mouse neuroblastoma cells, NEUROSCI L, 269(2), 1999, pp. 83-86
Authors:
Dermaut, B
Cruts, M
Slooter, AJC
Van Gestel, S
De Jonghe, C
Vanderstichele, H
Vanmechelen, E
Breteler, MM
Hofman, A
van Duijn, CM
Van Broeckhoven, C
Citation: B. Dermaut et al., The Glu318Gly substitution in presenilin 1 is not causally related to Alzheimer disease, AM J HU GEN, 64(1), 1999, pp. 290-292
Authors:
De Jonghe, C
Tysoe, C
Cruts, M
Vanderhoeven, I
Vanderstichele, H
Vanmechelen, E
Van Broeckhoven, C
Rubinsztein, DC
Hendriks, L
Citation: C. De Jonghe et al., A presenilin-1 truncating mutation causing Alzheimer's disease, ALZHEIMER'S DISEASE AND RELATED DISORDERS, 1999, pp. 81-86
Authors:
Dermaut, B
Cruts, M
Slooter, AJC
Van Gestel, S
De Jonghe, C
Backhovens, H
Vanderstichele, H
Vanmechelen, E
Breteler, MMB
Hofman, A
Hendriks, L
Van Duijn, CM
Van Broeckhoven, C
Citation: B. Dermaut et al., Glu318Gly in presenilin-1 is a neutral mutation in relation to dementia: The Rotterdam study, ALZHEIMER'S DISEASE AND RELATED DISORDERS, 1999, pp. 87-92