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Results: 1-25/26
Authors:
Patel, L
Pass, I
Coxon, P
Downes, CP
Smith, SA
Macphee, CH
Citation: L. Patel et al., Tumor suppressor and anti-inflammatory actions of PPAR gamma agonists are mediated via upregulation of PTEN, CURR BIOL, 11(10), 2001, pp. 764-768
Authors:
Downes, CP
Bennett, D
McConnachie, G
Leslie, NR
Pass, I
MacPhee, C
Patel, L
Gray, A
Citation: Cp. Downes et al., Antagonism of PI 3-kinase-dependent signalling pathways by the tumour suppressor protein, PTEN, BIOCH SOC T, 29, 2001, pp. 846-851
Authors:
Hill, E
Olusanya, O
van der Kaay, J
Downes, CP
Andrews, PD
Swedlow, JR
Smythe, E
Citation: E. Hill et al., Regulation of clathrin-coated vesicle formation, BIOCH SOC T, 29, 2001, pp. 375-377
Authors:
Leslie, NR
Bennett, D
Gray, A
Pass, I
Hoang-Xuan, K
Downes, CP
Citation: Nr. Leslie et al., Targeting mutants of PTEN reveal distinct subsets of tumour suppressor functions, BIOCHEM J, 357, 2001, pp. 427-435
Authors:
Hill, E
van der Kaay, J
Downes, CP
Smythe, E
Citation: E. Hill et al., The role of dynamin and its binding partners in coated pit invagination and scission, J CELL BIOL, 152(2), 2001, pp. 309-323
Authors:
Hajduch, E
Balendran, A
Batty, IH
Litherland, GJ
Blair, AS
Downes, CP
Hundal, HS
Citation: E. Hajduch et al., Ceramide impairs the insulin-dependent membrane recruitment of Protein Kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells, DIABETOLOG, 44(2), 2001, pp. 173-183
Authors:
Parekh, DB
Katso, RMT
Leslie, NR
Downes, CP
Procyk, KJ
Waterfield, MD
Parker, PJ
Citation: Db. Parekh et al., beta 1-Integrin and PTEN control the phosphorylation of protein kinase C, BIOCHEM J, 352, 2000, pp. 425-433
Authors:
Dowler, S
Currie, RA
Campbell, DG
Deak, M
Kular, G
Downes, CP
Alessi, DR
Citation: S. Dowler et al., Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities, BIOCHEM J, 351, 2000, pp. 19-31
Authors:
Fleming, IN
Gray, A
Downes, CP
Citation: In. Fleming et al., Regulation of the Rac1-specific exchange factor Tiam1 involves both phosphoinositide 3-kinase-dependent and -independent components, BIOCHEM J, 351, 2000, pp. 173-182
Authors:
Leslie, NR
Gray, A
Pass, I
Orchiston, EA
Downes, CP
Citation: Nr. Leslie et al., Analysis of the cellular functions of PTEN using catalytic domain and C-terminal mutations: differential effects of C-terminal deletion on signallingpathways downstream of phosphoinositide 3-kinase, BIOCHEM J, 346, 2000, pp. 827-833
Authors:
Harvey, J
McKay, NG
Walker, KS
Van der Kaay, J
Downes, CP
Ashford, MLJ
Citation: J. Harvey et al., Essential role of phosphoinositide 3-kinase in leptin-induced K-ATP channel activation in the rat CRI-G1 insulinoma cell line, J BIOL CHEM, 275(7), 2000, pp. 4660-4669
Authors:
Tang, XW
Downes, CP
Whetton, AD
Owen-Lynch, PJ
Citation: Xw. Tang et al., Role of phosphatidylinositol 3-kinase and specific protein kinase B isoforms in the suppression of apoptosis mediated by the Abelson protein-tyrosinekinase, J BIOL CHEM, 275(17), 2000, pp. 13142-13148
Authors:
Shinomura, T
del Rio, E
Breen, KC
Downes, CP
McLaughlin, M
Citation: T. Shinomura et al., Activation of phospholipase D by metabotropic glutamate receptor agonists in rat cerebrocortical synaptosomes, BR J PHARM, 131(5), 2000, pp. 1011-1018
Authors:
Balendran, A
Casamayor, A
Deak, M
Paterson, A
Gaffney, P
Currie, R
Downes, CP
Alessi, DR
Citation: A. Balendran et al., PDK1 acquires PDK2 activity in the presence of a synthetic peptide derivedfrom the carboxyl terminus of PRK2, CURR BIOL, 9(8), 1999, pp. 393-404
Authors:
del Rio, E
Mclaughlin, M
Downes, CP
Nicholls, DG
Citation: E. Del Rio et al., Differential coupling of G-protein-linked receptors to Ca2+ mobilization through inositol(1,4,5)trisphosphate or ryanodine receptors in cerebellar granule cells in primary culture, EUR J NEURO, 11(9), 1999, pp. 3015-3022
Authors:
Ponnambalam, S
Clough, S
Downes, CP
Lucocq, JM
McLauchlan, HJ
Towler, MC
Citation: S. Ponnambalam et al., Lipid kinases and trans-Golgi network membrane dynamics, BIOCH SOC T, 27(4), 1999, pp. 670-673
Authors:
Gray, A
Van der Kaay, J
Downes, CP
Citation: A. Gray et al., The pleckstrin homology domains of protein kinase B and GRP1 (general receptor for phosphoinositides-1) are sensitive and selective probes for the cellular detection of phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 3,4,5-trisphosphate in vivo, BIOCHEM J, 344, 1999, pp. 929-936
Authors:
Dowler, S
Currie, RA
Downes, CP
Alessi, DR
Citation: S. Dowler et al., DAPP1: a dual adaptor for phosphotyrosine and 3-phosphoinositides, BIOCHEM J, 342, 1999, pp. 7-12
Authors:
Currie, RA
Walker, KS
Gray, A
Deak, M
Casamayor, A
Downes, CP
Cohen, P
Alessi, DR
Lucocq, J
Citation: Ra. Currie et al., Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1, BIOCHEM J, 337, 1999, pp. 575-583
Authors:
Van der Kaay, J
Beck, M
Gray, A
Downes, CP
Citation: J. Van Der Kaay et al., Distinct phosphatidylinositol 3-kinase lipid products accumulate upon oxidative and osmotic stress and lead to different cellular responses, J BIOL CHEM, 274(50), 1999, pp. 35963-35968
Authors:
Hajduch, E
Rencurel, F
Balendran, A
Batty, IH
Downes, CP
Hundal, HS
Citation: E. Hajduch et al., Serotonin (5-hydroxytryptamine), a novel regulator of glucose transport inrat skeletal muscle, J BIOL CHEM, 274(19), 1999, pp. 13563-13568
Authors:
Fleming, IN
Elliott, CM
Buchanan, FG
Downes, CP
Exton, JH
Citation: In. Fleming et al., Ca2+/calmodulin-dependent protein kinase II regulates Tiam1 by reversible protein phosphorylation, J BIOL CHEM, 274(18), 1999, pp. 12753-12758
Authors:
Deak, M
Casamayor, A
Currie, RA
Downes, CP
Alessi, DR
Citation: M. Deak et al., Characterisation of a plant 3-phosphoinositide-dependent protein kinase-1 homologue which contains a pleckstrin homology domain, FEBS LETTER, 451(3), 1999, pp. 220-226
Authors:
Downes, CP
Citation: Cp. Downes, Subsection - Lipids in signalling and recognition - Foreword, BBA-MOL C B, 1436(1-2), 1998, pp. 1-3
Authors:
Alessi, DR
Downes, CP
Citation: Dr. Alessi et Cp. Downes, The role of PI 3-kinase in insulin action, BBA-MOL C B, 1436(1-2), 1998, pp. 151-164