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Results: 1-16 |
Results: 16
Modification of the Fc region of a primatized IgG antibody to human CD4 retains its ability to modulate CD4 receptors but does not deplete CD4(+) T cells in chimpanzees
Authors: Newman, R Hariharan, K Reff, M Anderson, DR Braslawsky, G Santoro, D Hanna, N Bugelski, PJ Brigham-Burke, M Crysler, C Gagnon, RC Dal Monte, P Doyle, ML Hensley, PC Reddy, MP Sweet, RW Truneh, A
Citation: R. Newman et al., Modification of the Fc region of a primatized IgG antibody to human CD4 retains its ability to modulate CD4 receptors but does not deplete CD4(+) T cells in chimpanzees, CLIN IMMUNO, 98(2), 2001, pp. 164-174
Identification, substrate specificity, and inhibition of the Streptococcuspneumoniae beta-ketoacyl-acyl carrier protein synthase III (FabH)
Authors: Khandekar, SS Gentry, DR Van Aller, GS Warren, P Xiang, H Silverman, C Doyle, ML Chambers, PA Konstantinidis, AK Brandt, M Daines, RA Lonsdale, JT
Citation: Ss. Khandekar et al., Identification, substrate specificity, and inhibition of the Streptococcuspneumoniae beta-ketoacyl-acyl carrier protein synthase III (FabH), J BIOL CHEM, 276(32), 2001, pp. 30024-30030
Subunit-subunit interactions in trimeric arginase - Generation of active monomers by mutation of a single amino acid
Authors: Lavulo, LT Sossong, TM Brigham-Burke, MR Doyle, ML Cox, JD Christianson, DW Ash, DE
Citation: Lt. Lavulo et al., Subunit-subunit interactions in trimeric arginase - Generation of active monomers by mutation of a single amino acid, J BIOL CHEM, 276(17), 2001, pp. 14242-14248
Steady-state kinetic characterization of substrates and metal-ion specificities of the full-length and N-terminally truncated recombinant human methionine aminopeptidases (type 2)
Authors: Yang, G Kirkpatrick, RB Ho, T Zhang, GF Liang, PH Johanson, KO Casper, DJ Doyle, ML Marino, JP Thompson, SK Chen, WF Tew, DG Meek, TD
Citation: G. Yang et al., Steady-state kinetic characterization of substrates and metal-ion specificities of the full-length and N-terminally truncated recombinant human methionine aminopeptidases (type 2), BIOCHEM, 40(35), 2001, pp. 10645-10654
Evaluating energetics of erythropoietin ligand binding to homodimerized receptor extracellular domains
Authors: Hensley, P Doyle, ML Myszka, DG Woody, RW Brigham-Burke, MR Erickson-Miller, CL Griffin, CA Jones, CS McNulty, DE O'Brien, SP Amegadzie, BY MacKenzie, L Ryan, MD Young, PR
Citation: P. Hensley et al., Evaluating energetics of erythropoietin ligand binding to homodimerized receptor extracellular domains, METH ENZYM, 323, 2000, pp. 177-207
Measurement of protein interaction bioenergetics: Application to structural variants of anti-sCD4 antibody
Authors: Doyle, ML Brigham-Burke, M Blackburn, MN Brooks, IS Smith, TM Newman, R Reff, M Stafford, WF Sweet, RW Truneh, A Hensley, P O'Shannessy, DJ
Citation: Ml. Doyle et al., Measurement of protein interaction bioenergetics: Application to structural variants of anti-sCD4 antibody, METH ENZYM, 323, 2000, pp. 207-230
Energetics of the HIV gp120-CD4 binding reaction
Authors: Myszka, DG Sweet, RW Hensley, P Brigham-Burke, M Kwong, PD Hendrickson, WA Wyatt, R Sodroski, J Doyle, ML
Citation: Dg. Myszka et al., Energetics of the HIV gp120-CD4 binding reaction, P NAS US, 97(16), 2000, pp. 9026-9031
Elimination of Fc receptor-dependent effector functions of a modified IgG4monoclonal antibody to human CD4
Authors: Reddy, MP Kinney, CAS Chaikin, MA Payne, A Fishman-Lobell, J Tsui, P Dal Monte, PR Doyle, ML Brigham-Burke, MR Anderson, D Reff, M Newman, R Hanna, N Sweet, RW Truneh, A
Citation: Mp. Reddy et al., Elimination of Fc receptor-dependent effector functions of a modified IgG4monoclonal antibody to human CD4, J IMMUNOL, 164(4), 2000, pp. 1925-1933
Temperature-sensitive differential affinity of TRAIL for its receptors - DR5 is the highest affinity receptor
Authors: Truneh, A Sharma, S Silverman, C Khandekar, S Reddy, MP Deen, KC Mclaughlin, MM Srinivasula, SM Livi, GP Marshall, LA Alnemri, ES Williams, WV Doyle, ML
Citation: A. Truneh et al., Temperature-sensitive differential affinity of TRAIL for its receptors - DR5 is the highest affinity receptor, J BIOL CHEM, 275(30), 2000, pp. 23319-23325
Identification and initial characterization of four novel members of the interleukin-1 family
Authors: Kumar, S McDonnell, PC Lehr, R Tierney, L Tzimas, MN Griswold, DE Capper, EA Tal-Singer, R Wells, GI Doyle, ML Young, PR
Citation: S. Kumar et al., Identification and initial characterization of four novel members of the interleukin-1 family, J BIOL CHEM, 275(14), 2000, pp. 10308-10314
Synergistic inhibitor binding to Streptococcus pneumoniae 5-enolpyruvylshikimate-3-phosphate synthase with both monovalent cations and substrate
Authors: Du, WS Liu, WS Payne, DJ Doyle, ML
Citation: Ws. Du et al., Synergistic inhibitor binding to Streptococcus pneumoniae 5-enolpyruvylshikimate-3-phosphate synthase with both monovalent cations and substrate, BIOCHEM, 39(33), 2000, pp. 10140-10146
Rational design of femtomolar inhibitors of isoleucyl tRNA synthetase froma binding model for pseudomonic acid-A
Authors: Brown, MJB Mensah, LM Doyle, ML Broom, NJP Osbourne, N Forrest, AK Richardson, CM O'Hanlon, PJ Pope, AJ
Citation: Mjb. Brown et al., Rational design of femtomolar inhibitors of isoleucyl tRNA synthetase froma binding model for pseudomonic acid-A, BIOCHEM, 39(20), 2000, pp. 6003-6011
Expression, purification, and crystallization of the Escherichia coli selenomethionyl beta-ketoacyl-acyl carrier protein synthase III
Authors: Khandekar, SS Konstantinidis, AK Silverman, C Janson, CA McNulty, DE Nwagwu, S Van Aller, GS Doyle, ML Kane, JF Qiu, XY Lonsdale, J
Citation: Ss. Khandekar et al., Expression, purification, and crystallization of the Escherichia coli selenomethionyl beta-ketoacyl-acyl carrier protein synthase III, BIOC BIOP R, 270(1), 2000, pp. 100-107
A direct comparison of the activities of two humanized respiratory syncytial virus monoclonal antibodies: MEDI-493 and RSHZ19
Authors: Johnson, S Griego, SD Pfarr, DS Doyle, ML Woods, R Carlin, D Prince, GA Koenig, S Young, JF Dillon, SB
Citation: S. Johnson et al., A direct comparison of the activities of two humanized respiratory syncytial virus monoclonal antibodies: MEDI-493 and RSHZ19, J INFEC DIS, 180(1), 1999, pp. 35-40
Structural and functional properties of human hemoglobins reassembled after synthesis in Escherichia coli
Authors: Hui, HL Kavanaugh, JS Doyle, ML Wierzba, A Rogers, PH Arnone, A Holt, JM Ackers, GK Noble, RW
Citation: Hl. Hui et al., Structural and functional properties of human hemoglobins reassembled after synthesis in Escherichia coli, BIOCHEM, 38(3), 1999, pp. 1040-1049
Dissection of the nucleotide and metal-phosphate binding sites in cAMP-dependent protein kinase
Authors: Herberg, FW Doyle, ML Cox, S Taylor, SS
Citation: Fw. Herberg et al., Dissection of the nucleotide and metal-phosphate binding sites in cAMP-dependent protein kinase, BIOCHEM, 38(19), 1999, pp. 6352-6360
Risultati: 1-16 |