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Results: 1-23 |
Results: 23
BIFUNCTIONAL PEPTIDE BORONATE INHIBITORS OF THROMBIN - CRYSTALLOGRAPHIC ANALYSIS OF INHIBITION ENHANCED BY LINKAGE TO AN EXOSITE-1 BINDING PEPTIDE
Authors: SKORDALAKES E ELGENDY S GOODWIN CA GREEN D SCULLY MF KAKKAR VV FREYSSINET JM DODSON G DEADMAN JJ
Citation: E. Skordalakes et al., BIFUNCTIONAL PEPTIDE BORONATE INHIBITORS OF THROMBIN - CRYSTALLOGRAPHIC ANALYSIS OF INHIBITION ENHANCED BY LINKAGE TO AN EXOSITE-1 BINDING PEPTIDE, Biochemistry (Easton), 37(41), 1998, pp. 14420-14427
ELUCIDATION OF THE THROMBIN INHIBITORY MECHANISM OF TRIPEPTIDE BORONATES WITH NEUTRAL P1 SIDE-CHAINS
Authors: DEADMAN JJ SKORDALAKES E ELGENDY S GREEN D GOODWIN CA CLAESON G SCULLY MF KAKKAR VV GAMBLIN S DODSON G
Citation: Jj. Deadman et al., ELUCIDATION OF THE THROMBIN INHIBITORY MECHANISM OF TRIPEPTIDE BORONATES WITH NEUTRAL P1 SIDE-CHAINS, Thrombosis and haemostasis, 1997, pp. 2024-2024
Z-D-PHE-PRO-BORO ETHYL ISOTHIOURONIUM - A SLOW BINDING, ESSENTIALLY IRREVERSIBLE, INHIBITOR OF COAGULATION PROTEASES
Authors: GOODWIN CA ELGENDY S CHINO N GREEN D SCULLY MF CLAESON G DEADMAN JJ
Citation: Ca. Goodwin et al., Z-D-PHE-PRO-BORO ETHYL ISOTHIOURONIUM - A SLOW BINDING, ESSENTIALLY IRREVERSIBLE, INHIBITOR OF COAGULATION PROTEASES, Thrombosis and haemostasis, 1997, pp. 2036-2036
CRYSTALLOGRAPHIC ANALYSIS OF THE BINDING MECHANISM OF BIFUNCTIONAL PEPTIDE BORONATE TO HUMAN ALPHA-THROMBIN AND THEIR INHIBITORY ACTIVITY
Authors: SKORDALAKES E ELGENDY S GREEN D GOODWIN CA SCULLY MF CLAESON G KAKKAR VV GAMBLIN S DODSON G DEADMAN JJ
Citation: E. Skordalakes et al., CRYSTALLOGRAPHIC ANALYSIS OF THE BINDING MECHANISM OF BIFUNCTIONAL PEPTIDE BORONATE TO HUMAN ALPHA-THROMBIN AND THEIR INHIBITORY ACTIVITY, Thrombosis and haemostasis, 1997, pp. 2387-2387
DESIGN OF A NOVEL CLASS OF BIFUNCTIONAL THROMBIN INHIBITORS, SYNTHESIZED BY THE FIRST APPLICATION OF PEPTIDE BORONATES IN SOLID-PHASE CHEMISTRY
Authors: ELGENDY S PATEL G GREEN D GOODWIN CA SCULLY MF HUSMAN W SKORDALAKES E KAKKAR VV DEADMAN JJ
Citation: S. Elgendy et al., DESIGN OF A NOVEL CLASS OF BIFUNCTIONAL THROMBIN INHIBITORS, SYNTHESIZED BY THE FIRST APPLICATION OF PEPTIDE BORONATES IN SOLID-PHASE CHEMISTRY, Tetrahedron letters, 38(18), 1997, pp. 3305-3308
CRYSTALLOGRAPHIC STRUCTURES OF HUMAN ALPHA-THROMBIN COMPLEXED TO PEPTIDE BORONIC ACIDS LACKING A POSITIVE CHARGE AT P1 - EVIDENCE OF NOVEL INTERACTIONS
Authors: SKORDALAKES E TYRELL R ELGENDY S GOODWIN CA GREEN D DODSON G SCULLY MF FREYSSINET JMH KAKKAR VV DEADMAN JJ
Citation: E. Skordalakes et al., CRYSTALLOGRAPHIC STRUCTURES OF HUMAN ALPHA-THROMBIN COMPLEXED TO PEPTIDE BORONIC ACIDS LACKING A POSITIVE CHARGE AT P1 - EVIDENCE OF NOVEL INTERACTIONS, Journal of the American Chemical Society, 119(41), 1997, pp. 9935-9936
THE SYNTHESIS AND FAB MASS ANALYSIS OF O,O-DIALKYL 1-BENZYLAMINOBENZYLPHOSPHONATES, PRECURSORS OF IMPORTANT STRUCTURAL UNITS IN ANTITHROMBOTIC TRIPEPTIDES
Authors: GREEN D ELGENDY S PATEL G SKORDALAKES E HUSMAN W KAKKAR VV DEADMAN J
Citation: D. Green et al., THE SYNTHESIS AND FAB MASS ANALYSIS OF O,O-DIALKYL 1-BENZYLAMINOBENZYLPHOSPHONATES, PRECURSORS OF IMPORTANT STRUCTURAL UNITS IN ANTITHROMBOTIC TRIPEPTIDES, Phosphorus, sulfur and silicon and the related elements, 118, 1996, pp. 271-291
THE FACILE SYNTHESIS OF 1-AMINOPHOSPHONATES FROM 1-NITROPHOSPHONATE PRECURSORS
Authors: GREEN D ELGENDY S PATEL G BABAN JA SKORDALAKES E HUSMAN W KAKKAR VV DEADMAN J
Citation: D. Green et al., THE FACILE SYNTHESIS OF 1-AMINOPHOSPHONATES FROM 1-NITROPHOSPHONATE PRECURSORS, Phosphorus, sulfur and silicon and the related elements, 113(1-4), 1996, pp. 303-306
HEPARIN ENHANCES THE CATALYTIC ACTIVITY OF DES-ETW-THROMBIN
Authors: GOODWIN CA DEADMAN JJ LEBONNIEC BF ELGENDY S KAKKAR VV SCULLY MF
Citation: Ca. Goodwin et al., HEPARIN ENHANCES THE CATALYTIC ACTIVITY OF DES-ETW-THROMBIN, Biochemical journal, 315, 1996, pp. 77-83
THE FACILE SYNTHESIS OF O,O-DIALKYL ALPHA-HALOBENZYLPHOSPHONATES FROMO,O-DIALKYL ALPHA-HYDROXYBENZYLPHOSPHONATES
Authors: GREEN D ELGENDY S PATEL G BABAN JA SKORDALAKES E HUSMAN W KAKKAR VV DEADMAN J
Citation: D. Green et al., THE FACILE SYNTHESIS OF O,O-DIALKYL ALPHA-HALOBENZYLPHOSPHONATES FROMO,O-DIALKYL ALPHA-HYDROXYBENZYLPHOSPHONATES, Tetrahedron, 52(30), 1996, pp. 10215-10224
CHARACTERIZATION OF A CLASS OF PEPTIDE BORONATES WITH NEUTRAL P1 SIDE-CHAINS AS HIGHLY SELECTIVE PRODRUG INHIBITORS OF THROMBIN
Authors: DEADMAN J ELGENDY S GOODWIN C GREEN D BABAN J PATEL G SKORDALAKES E CHINO N CLAESON G
Citation: J. Deadman et al., CHARACTERIZATION OF A CLASS OF PEPTIDE BORONATES WITH NEUTRAL P1 SIDE-CHAINS AS HIGHLY SELECTIVE PRODRUG INHIBITORS OF THROMBIN, Thrombosis and haemostasis, 73(6), 1995, pp. 924-924
ENHANCEMENT OF THE SPECIFICITY OF PEPTIDE BOROISOTHIOURONIUM INHIBITOR OF THROMBIN
Authors: DEADMAN J GOODWIN C ELGENDY S CHINO N SCULLY M KAKKAR V
Citation: J. Deadman et al., ENHANCEMENT OF THE SPECIFICITY OF PEPTIDE BOROISOTHIOURONIUM INHIBITOR OF THROMBIN, Thrombosis and haemostasis, 73(6), 1995, pp. 925-925
ANTITHROMBOTIC AND ANTICOAGULANT PROPERTIES OF NOVEL PEPTIDE BORONIC ACID THROMBIN INHIBITORS - COMPARISON WITH HEPARIN AND HIRUDIN
Authors: ESMAIL AF DUPE RJ GODDARD M BRIGGS IM BABBAN JA ELGENDY S GREEN D DEADMAN J SCULLY MF KAKKAR VV
Citation: Af. Esmail et al., ANTITHROMBOTIC AND ANTICOAGULANT PROPERTIES OF NOVEL PEPTIDE BORONIC ACID THROMBIN INHIBITORS - COMPARISON WITH HEPARIN AND HIRUDIN, Thrombosis and haemostasis, 73(6), 1995, pp. 1318-1318
CHARACTERIZATION OF A CLASS OF PEPTIDE BORONATES WITH NEUTRAL P1 SIDE-CHAINS AS HIGHLY SELECTIVE INHIBITORS OF THROMBIN
Authors: DEADMAN JJ ELGENDY S GOODWIN CA GREEN D BABAN JA PATEL G SKORDALAKES E CHINO N CLAESON G KAKKAR VV SCULLY MF
Citation: Jj. Deadman et al., CHARACTERIZATION OF A CLASS OF PEPTIDE BORONATES WITH NEUTRAL P1 SIDE-CHAINS AS HIGHLY SELECTIVE INHIBITORS OF THROMBIN, Journal of medicinal chemistry, 38(9), 1995, pp. 1511-1522
RHODIUM(I)-CATALYZED HYDROBORATION OF 1-HALO-1-ALKENES
Authors: ELGENDY S PATEL G KAKKAR VV CLAESON G GREEN D SKORDALAKES E BABAN JA DEADMAN J
Citation: S. Elgendy et al., RHODIUM(I)-CATALYZED HYDROBORATION OF 1-HALO-1-ALKENES, Tetrahedron letters, 35(15), 1994, pp. 2435-2436
THE SYNTHESIS OF 1-AMINOBENZYLPHOSPHONIC ACIDS FROM BENZYLIDENEDIPHENYLMETHYLAMINES, FOR USE AS STRUCTURAL UNITS IN ANTITHROMBOTIC TRIPEPTIDES
Authors: GREEN D PATEL G ELGENDY S BABAN JA CLAESON G KAKKAR VV DEADMAN J
Citation: D. Green et al., THE SYNTHESIS OF 1-AMINOBENZYLPHOSPHONIC ACIDS FROM BENZYLIDENEDIPHENYLMETHYLAMINES, FOR USE AS STRUCTURAL UNITS IN ANTITHROMBOTIC TRIPEPTIDES, Tetrahedron, 50(17), 1994, pp. 5099-5108
FACILE ROUTES TO 1-HALO-1-ALKYL BORONIC ESTERS AS PRECURSORS FOR NOVEL THROMBIN INHIBITORS
Authors: ELGENDY S CLAESON G KAKKAR VV GREEN D PATEL G GOODWIN CA BABAN JA SCULLY MF DEADMAN J
Citation: S. Elgendy et al., FACILE ROUTES TO 1-HALO-1-ALKYL BORONIC ESTERS AS PRECURSORS FOR NOVEL THROMBIN INHIBITORS, Tetrahedron, 50(12), 1994, pp. 3803-3812
PEPTIDE BOROISOTHIOURONIUM COMPOUNDS AS INHIBITORS OF THROMBIN - A SPECIFICITY STUDY ACCORDING TO THE P3 RESIDUE
Authors: GOODWIN C SCULLY MF DEADMAN J CHINO N ELGENDY S KAKKAR VV CLAESON G
Citation: C. Goodwin et al., PEPTIDE BOROISOTHIOURONIUM COMPOUNDS AS INHIBITORS OF THROMBIN - A SPECIFICITY STUDY ACCORDING TO THE P3 RESIDUE, Thrombosis and haemostasis, 69(6), 1993, pp. 667-667
IN-VITRO AND IN-VIVO EVALUATION OF PEPTIDE ISOSTERE THROMBIN INHIBITORS
Authors: DEADMAN J SCULLY MF CHENG I CLAESON G PATEL G ELGENDY S KAKKAR VV
Citation: J. Deadman et al., IN-VITRO AND IN-VIVO EVALUATION OF PEPTIDE ISOSTERE THROMBIN INHIBITORS, Thrombosis and haemostasis, 69(6), 1993, pp. 669-669
BORO-PEPTIDOMIMETIC CONTAINING A NEUTRAL SIDE-CHAIN AT THE PI POSITION AS SELECTIVE INHIBITORS OF THROMBIN STRUCTURE-FUNCTION-RELATIONSHIPS
Authors: GOODWIN C DEADMAN J SCULLY MF ELGENDY S KAKKAR VV CLAESON G
Citation: C. Goodwin et al., BORO-PEPTIDOMIMETIC CONTAINING A NEUTRAL SIDE-CHAIN AT THE PI POSITION AS SELECTIVE INHIBITORS OF THROMBIN STRUCTURE-FUNCTION-RELATIONSHIPS, Thrombosis and haemostasis, 69(6), 1993, pp. 886-886
HIGHLY SPECIFIC, BOROPEPTIDOMIMETIC INHIBITORS OF THROMBIN - IN-VIVO CHARACTERIZATION
Authors: DEADMAN J ELGENDY S CLAESON G BABAN J SCULLY MF GOODWIN C EDMONDSON RA PHILLIPS M KAKKAR VV
Citation: J. Deadman et al., HIGHLY SPECIFIC, BOROPEPTIDOMIMETIC INHIBITORS OF THROMBIN - IN-VIVO CHARACTERIZATION, Thrombosis and haemostasis, 69(6), 1993, pp. 887-887
BORO-PEPTIDOMIMETIC INHIBITORS OF THROMBIN WITH POSITIVE OR NEUTRAL CHARGE AT PI SITE - DIFFERENCES IN AQUEOUS STABILITY
Authors: SCULLY MF GOODWIN C DEADMAN J ELGENDY S KAKKAR VV CLAESON G
Citation: Mf. Scully et al., BORO-PEPTIDOMIMETIC INHIBITORS OF THROMBIN WITH POSITIVE OR NEUTRAL CHARGE AT PI SITE - DIFFERENCES IN AQUEOUS STABILITY, Thrombosis and haemostasis, 69(6), 1993, pp. 887-887
THE FACILE SYNTHESIS OF O,O-DIALKYL 1-AMINOALKANEPHOSPHONATES
Authors: GREEN D PATEL G ELGENDY S BABAN JA CLAESON G KAKKAR VV DEADMAN J
Citation: D. Green et al., THE FACILE SYNTHESIS OF O,O-DIALKYL 1-AMINOALKANEPHOSPHONATES, Tetrahedron letters, 34(43), 1993, pp. 6917-6920
Risultati: 1-23 |