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Results: 1-25 | 26-46
Results: 1-25/46
Pharmacogenetics of the human drug-transporter gene MDR1: impact of polymorphisms on pharmacotherapy
Authors: Brinkmann, U Roots, I Eichelbaum, M
Citation: U. Brinkmann et al., Pharmacogenetics of the human drug-transporter gene MDR1: impact of polymorphisms on pharmacotherapy, DRUG DISC T, 6(16), 2001, pp. 835-839
CYP3A genetics in drug metabolism
Authors: Eichelbaum, M Burk, O
Citation: M. Eichelbaum et O. Burk, CYP3A genetics in drug metabolism, NAT MED, 7(3), 2001, pp. 285-287
Comprehensive analysis of the genetic factors determining expression and function of hepatic CYP2D6
Authors: Zanger, UM Fischer, J Raimundo, S Stuven, T Evert, BO Schwab, M Eichelbaum, M
Citation: Um. Zanger et al., Comprehensive analysis of the genetic factors determining expression and function of hepatic CYP2D6, PHARMACOGEN, 11(7), 2001, pp. 573-585
Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver (vol 11, pg 399, 2001)
Authors: Long, T Klein, K Fischer, J Nussler, AK Neuhaus, P Hofmann, U Eichelbaum, M Schwab, M Zanger, UM
Citation: T. Long et al., Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver (vol 11, pg 399, 2001), PHARMACOGEN, 11(7), 2001, pp. 643-643
A tribute to Frank Gonzalez
Authors: Eichelbaum, M Evans, W Yamazoe, Y
Citation: M. Eichelbaum et al., A tribute to Frank Gonzalez, PHARMACOGEN, 11(5), 2001, pp. 371-371
Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver
Authors: Lang, T Klein, K Fischer, J Nussler, AK Neuhaus, P Hofmann, U Eichelbaum, M Schwab, M Zanger, UM
Citation: T. Lang et al., Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver, PHARMACOGEN, 11(5), 2001, pp. 399-415
The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56(+) natural killer cells
Authors: Hitzl, M Drescher, S van der Kuip, H Schaffeler, E Fischer, J Schwab, M Eichelbaum, M Fromm, MF
Citation: M. Hitzl et al., The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56(+) natural killer cells, PHARMACOGEN, 11(4), 2001, pp. 293-298
Cellular localization and regional distribution of CYP2D6 mRNA and proteinexpression in human brain
Authors: Siegle, I Fritz, P Eckhardt, K Zanger, UM Eichelbaum, M
Citation: I. Siegle et al., Cellular localization and regional distribution of CYP2D6 mRNA and proteinexpression in human brain, PHARMACOGEN, 11(3), 2001, pp. 237-245
Allele and genotype frequencies of polymorphic cytochromes P4502D6, 2C19 and 2E1 in Aborigines from Western Australia
Authors: Griese, EU Ilett, KF Kitteringham, NR Eichelbaum, M Powell, H Spargo, RM LeSouef, PN Musk, AW Minchin, RF
Citation: Eu. Griese et al., Allele and genotype frequencies of polymorphic cytochromes P4502D6, 2C19 and 2E1 in Aborigines from Western Australia, PHARMACOGEN, 11(1), 2001, pp. 69-76
Microsomal epoxide hydrolase expression as a predictor of tamoxifen response in primary breast cancer: A retrospective exploratory study with long-term follow-up
Authors: Fritz, P Murdter, TE Eichelbaum, M Siegle, I Weissert, M Zanger, UM
Citation: P. Fritz et al., Microsomal epoxide hydrolase expression as a predictor of tamoxifen response in primary breast cancer: A retrospective exploratory study with long-term follow-up, J CL ONCOL, 19(1), 2001, pp. 3-9
Frequency of C3435T polymorphism of MDR1 gene in African people
Authors: Schaeffeler, E Eichelbaum, M Brinkmann, U Penger, A Asante-Poku, S Zanger, UM Schwab, M
Citation: E. Schaeffeler et al., Frequency of C3435T polymorphism of MDR1 gene in African people, LANCET, 358(9279), 2001, pp. 383-384
Natural protein variants of pregnane X receptor with altered transactivation activity toward CYP3A4
Authors: Hustert, E Zibat, A Presecan-Siedel, E Eiselt, R Mueller, R Fuss, C Brehm, I Brinkmann, U Eichelbaum, M Wojnowski, L Burk, O
Citation: E. Hustert et al., Natural protein variants of pregnane X receptor with altered transactivation activity toward CYP3A4, DRUG META D, 29(11), 2001, pp. 1454-1459
P-glycoprotein-mediated transport of digitoxin, alpha-methyldigoxin and beta-acetyldigoxin
Authors: Pauli-Magnus, C Murdter, T Godel, A Mettang, T Eichelbaum, M Klotz, U Fromm, MF
Citation: C. Pauli-magnus et al., P-glycoprotein-mediated transport of digitoxin, alpha-methyldigoxin and beta-acetyldigoxin, N-S ARCH PH, 363(3), 2001, pp. 337-343
Nuclear receptor response elements mediate induction of intestinal MDR1 byrifampin
Authors: Geick, A Eichelbaum, M Burk, O
Citation: A. Geick et al., Nuclear receptor response elements mediate induction of intestinal MDR1 byrifampin, J BIOL CHEM, 276(18), 2001, pp. 14581-14587
Distribution of microsomal epoxide hydrolase in humans: An immunohistochemical study in normal tissues, and benign and malignant tumours
Authors: Coller, JK Fritz, P Zanger, UM Siegle, I Eichelbaum, M Kroemer, HK Murdter, TE
Citation: Jk. Coller et al., Distribution of microsomal epoxide hydrolase in humans: An immunohistochemical study in normal tissues, and benign and malignant tumours, HISTOCHEM J, 33(6), 2001, pp. 329-336
Shortcoming in the diagnosis of TPMT deficiency in a patient with Crohn's disease using phenotyping only
Authors: Schwab, M Schaeffeler, E Marx, C Zanger, U Aulitzky, W Eichelbaum, M
Citation: M. Schwab et al., Shortcoming in the diagnosis of TPMT deficiency in a patient with Crohn's disease using phenotyping only, GASTROENTY, 121(2), 2001, pp. 500-501
Determination of in vivo absorption, metabolism, and transport of drugs bythe human intestinal wall and liver with a novel perfusion technique
Authors: von Richter, O Greiner, B Fromm, MF Fraser, R Omari, T Barclay, ML Dent, J Somogyi, AA Eichelbaum, M
Citation: O. Von Richter et al., Determination of in vivo absorption, metabolism, and transport of drugs bythe human intestinal wall and liver with a novel perfusion technique, CLIN PHARM, 70(3), 2001, pp. 217-227
Disposition and pharmacologic effects of R/S-verapamil in patients with chronic atrial fibrillation: An investigation comparing single and multiple dosing
Authors: Busse, D Fromm, MF Morike, K Drescher, S Kuhlkamp, V Eichelbaum, M
Citation: D. Busse et al., Disposition and pharmacologic effects of R/S-verapamil in patients with chronic atrial fibrillation: An investigation comparing single and multiple dosing, CLIN PHARM, 69(5), 2001, pp. 324-332
Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects
Authors: Cascorbi, I Gerloff, T Johne, A Meisel, C Hoffmeyer, S Schwab, M Schaeffeler, E Eichelbaum, M Brinkmann, U Roots, I
Citation: I. Cascorbi et al., Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects, CLIN PHARM, 69(3), 2001, pp. 169-174
High-throughput genotyping of thiopurine S-methyltransferase by denaturingHPLC
Authors: Schaeffeler, E Lang, T Zanger, UM Eichelbaum, M Schwab, M
Citation: E. Schaeffeler et al., High-throughput genotyping of thiopurine S-methyltransferase by denaturingHPLC, CLIN CHEM, 47(3), 2001, pp. 548-555
Determination of propafenone and its phase I and phase II metabolites in plasma and urine by high-performance liquid chromatography-electrospray ionization mass spectrometry
Authors: Hofmann, U Pecia, M Heinkele, G Dilger, K Kroemer, HK Eichelbaum, M
Citation: U. Hofmann et al., Determination of propafenone and its phase I and phase II metabolites in plasma and urine by high-performance liquid chromatography-electrospray ionization mass spectrometry, J CHROMAT B, 748(1), 2000, pp. 113-123
Rapid and highly sensitive method for the determination of verapamil, [H-2(7)]verapamil and metabolites in biological fluids by liquid chromatography-mass spectrometry
Authors: von Richter, O Eichelbaum, M Schonberger, F Hofmann, U
Citation: O. Von Richter et al., Rapid and highly sensitive method for the determination of verapamil, [H-2(7)]verapamil and metabolites in biological fluids by liquid chromatography-mass spectrometry, J CHROMAT B, 738(1), 2000, pp. 137-147
Elucidation of the genetic basis of the common 'intermediate metabolizer' phenotype for drug oxidation by CYP2D6
Authors: Raimundo, S Fischer, R Eichelbaum, M Griese, EU Schwab, M Zanger, UM
Citation: S. Raimundo et al., Elucidation of the genetic basis of the common 'intermediate metabolizer' phenotype for drug oxidation by CYP2D6, PHARMACOGEN, 10(7), 2000, pp. 577-581
Psychotropic drug use, falls and hip fracture in the elderly
Authors: Schwab, M Roder, F Aleker, T Ammon, S Thon, KP Eichelbaum, M Klotz, U
Citation: M. Schwab et al., Psychotropic drug use, falls and hip fracture in the elderly, AGING-CLIN, 12(3), 2000, pp. 234-239
Variability of cyclophosphamide uptake into human bronchial carcinoma: consequences for local bioactivation
Authors: Bohnenstengel, F Friedel, G Ritter, CA McClellan, M Fritz, P Eichelbaum, M Linder, A Toomes, H Dierkesmann, R Kroemer, HK
Citation: F. Bohnenstengel et al., Variability of cyclophosphamide uptake into human bronchial carcinoma: consequences for local bioactivation, CANC CHEMOT, 45(1), 2000, pp. 63-68
Risultati: 1-25 | 26-46