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Results: 1-10 |
Results: 10

Authors: Etievant, C Kruczynski, A Barret, JM Tait, AS Kavallaris, M Hill, BT
Citation: C. Etievant et al., Markedly diminished drug resistance-inducing properties of vinflunine (20 ',20 '-difluoro-3 ',4 '-dihydrovinorelbine) relative to vinorelbine, identified in murine and human tumour cells in vivo and in vitro, CANC CHEMOT, 48(1), 2001, pp. 62-70

Authors: Hill, BT Moran, E Etievant, C Perrin, D Masterson, A Larkin, A Whelan, RDH
Citation: Bt. Hill et al., Low-dose twice-daily fractionated X-irradiation of ovarian tumor cells in vitro generates drug-resistant cells overexpressing two multidrug resistance-associated proteins, P-glycoprotein and MRP1, ANTI-CANC D, 11(3), 2000, pp. 193-200

Authors: van Hille, B Etievant, C Barret, JM Kruczynski, A Hill, BT
Citation: B. Van Hille et al., Characterization of the biological and biochemical activities of F 11782 and the bisdioxopiperazines, ICRF-187 and ICRF-193, two types of topoisomerase II catalytic inhibitors with distinctive mechanisms of action, ANTI-CANC D, 11(10), 2000, pp. 829-841

Authors: Etievant, C Kruczynski, A Barret, JM Perrin, D van Hille, B Guminski, Y Hill, BT
Citation: C. Etievant et al., F 11782, a dual inhibitor of topoisomerases I and II with an original mechanism of action in vitro, and markedly superior in vivo antitumour activity, relative to three other dual topoisomerase inhibitors, intoplicin, aclarubicin and TAS-103, CANC CHEMOT, 46(2), 2000, pp. 101-113

Authors: Barret, JM Etievant, C Hill, BT
Citation: Jm. Barret et al., In vitro synergistic effects of vinflunine, a novel fluorinated vinca alkaloid, in combination with other anticancer drugs, CANC CHEMOT, 45(6), 2000, pp. 471-476

Authors: Barret, JM Montaudon, D Etievant, C Perrin, D Kruczynski, A Robert, J Hill, BT
Citation: Jm. Barret et al., Detection of DNA-strand breaks in cells treated with F 11782, a catalytic inhibitor of topoisomerases I and II, ANTICANC R, 20(6B), 2000, pp. 4557-4562

Authors: Kruczynski, A Etievant, C Perrin, D Imbert, T Colpaert, F Hill, BT
Citation: A. Kruczynski et al., Preclinical antitumour activity of F 11782, a novel dual catalytic inhibitor of topoisomerases, BR J CANC, 83(11), 2000, pp. 1516-1524

Authors: Lobert, S Fahy, J Hill, BT Duflos, A Etievant, C Correia, JJ
Citation: S. Lobert et al., Vinca alkaloid-induced tubulin spiral formation correlates with cytotoxicity in the leukemic L1210 cell line, BIOCHEM, 39(39), 2000, pp. 12053-12062

Authors: Perrin, D van Hille, B Barret, JM Kruczynski, A Etievant, C Imbert, T Hill, BT
Citation: D. Perrin et al., F 11782, a novel epipodophylloid non-intercalating dual catalytic inhibitor of topoisomerases I and II with an original mechanism of action, BIOCH PHARM, 59(7), 2000, pp. 807-819

Authors: Barret, JM Etievant, C Fahy, J Lhomme, J Hill, BT
Citation: Jm. Barret et al., Novel artificial endonucleases inhibit base excision repair and potentiatethe cytotoxicity of DNA-damaging agents on L1210 cells, ANTI-CANC D, 10(1), 1999, pp. 55-65
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