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Results: 1-25 | 26-26
Results: 1-25/26
MOLECULAR BIOLOGICAL METHODS FOR CHARACTERIZING DRUG-METABOLIZING-ENZYMES IN HEPATIC AND EXTRAHEPATIC TISSUES
Authors: FRIEDBERG T
Citation: T. Friedberg, MOLECULAR BIOLOGICAL METHODS FOR CHARACTERIZING DRUG-METABOLIZING-ENZYMES IN HEPATIC AND EXTRAHEPATIC TISSUES, SKIN PHARMACOLOGY AND APPLIED SKIN PHYSIOLOGY, 11(2), 1998, pp. 61-69
EFFECT OF PHENYTOIN ON CYTOCHROME-P450 2B MESSENGER-RNA EXPRESSION INPRIMARY RAT ASTROCYTE CULTURES
Authors: IBACH B APPEL K GEBICKEHAERTER P MEYER RP FRIEDBERG T KNOTH R VOLK B
Citation: B. Ibach et al., EFFECT OF PHENYTOIN ON CYTOCHROME-P450 2B MESSENGER-RNA EXPRESSION INPRIMARY RAT ASTROCYTE CULTURES, Journal of neuroscience research, 54(3), 1998, pp. 402-411
DETERMINANTS OF THE SUBSTRATE-SPECIFICITY OF HUMAN CYTOCHROME-P-450 CYP2D6 - DESIGN AND CONSTRUCTION OF A MUTANT WITH TESTOSTERONE HYDROXYLASE-ACTIVITY
Authors: SMITH G MODI S PILLAI I LIAN LY SUTCLIFFE MJ PRITCHARD MP FRIEDBERG T ROBERTS GCK WOLF CR
Citation: G. Smith et al., DETERMINANTS OF THE SUBSTRATE-SPECIFICITY OF HUMAN CYTOCHROME-P-450 CYP2D6 - DESIGN AND CONSTRUCTION OF A MUTANT WITH TESTOSTERONE HYDROXYLASE-ACTIVITY, Biochemical journal, 331, 1998, pp. 783-792
DETOXIFICATION OF OPTICALLY-ACTIVE BAY-REGION AND FJORD-REGION POLYCYCLIC AROMATIC HYDROCARBON DIHYDRODIOL EPOXIDES BY HUMAN GLUTATHIONE TRANSFERASE P1-1 EXPRESSED IN CHINESE-HAMSTER V79 CELLS
Authors: SEIDEL A FRIEDBERG T LOLLMANN B SCHWIERZOK A FUNK M FRANK H HOLLER R OESCH F GLATT H
Citation: A. Seidel et al., DETOXIFICATION OF OPTICALLY-ACTIVE BAY-REGION AND FJORD-REGION POLYCYCLIC AROMATIC HYDROCARBON DIHYDRODIOL EPOXIDES BY HUMAN GLUTATHIONE TRANSFERASE P1-1 EXPRESSED IN CHINESE-HAMSTER V79 CELLS, Carcinogenesis (New York. Print), 19(11), 1998, pp. 1975-1981
CYTOCHROME P450S MEDIATE A NOVEL PATHWAY OF DRUG-RESISTANCE TO CYTOSTATIC COMPOUNDS
Authors: FRIEDBERG T DING SH BURCHELL B WOLF CR YAO DG
Citation: T. Friedberg et al., CYTOCHROME P450S MEDIATE A NOVEL PATHWAY OF DRUG-RESISTANCE TO CYTOSTATIC COMPOUNDS, Naunyn-Schmiedeberg's archives of pharmacology, 357(4), 1998, pp. 509-509
MAMMALIAN AND INVERTEBRATE MICROSOMAL EPOXIDE HYDROLASES DISPLAY OPPOSITE MEMBRANE ORIENTATION
Authors: MECKY A ARAND M HOLLER R FRIEDBERG T OESCH F
Citation: A. Mecky et al., MAMMALIAN AND INVERTEBRATE MICROSOMAL EPOXIDE HYDROLASES DISPLAY OPPOSITE MEMBRANE ORIENTATION, Naunyn-Schmiedeberg's archives of pharmacology, 357(4), 1998, pp. 515-515
A KERATINOCYTE-SPECIFIC EPOXYGENASE, CYP2B12, METABOLIZES ARACHIDONIC-ACID WITH UNUSUAL SELECTIVITY, PRODUCING A SINGLE MAJOR EPOXYEICOSATRIENOIC ACID
Authors: KEENEY DS SKINNER C WEI SZ FRIEDBERG T WATERMAN MR
Citation: Ds. Keeney et al., A KERATINOCYTE-SPECIFIC EPOXYGENASE, CYP2B12, METABOLIZES ARACHIDONIC-ACID WITH UNUSUAL SELECTIVITY, PRODUCING A SINGLE MAJOR EPOXYEICOSATRIENOIC ACID, The Journal of biological chemistry, 273(15), 1998, pp. 9279-9284
THE ROLE OF THE HYDROPHOBIC DOMAIN IN ORIENTING NATURAL SIGNAL SEQUENCES WITHIN THE ER MEMBRANE
Authors: EUSEBIO A FRIEDBERG T SPIESS M
Citation: A. Eusebio et al., THE ROLE OF THE HYDROPHOBIC DOMAIN IN ORIENTING NATURAL SIGNAL SEQUENCES WITHIN THE ER MEMBRANE, Experimental cell research, 241(1), 1998, pp. 181-185
BACTERIAL EXPRESSION OF FUNCTIONAL HUMAN P450 MONOOXYGENASE SYSTEMS FOR DRUG DEVELOPMENT
Authors: PRITCHARD M KUSIAK M HANLON S VOICE M ROBERTS J BURCHELL B WOLF CR FRIEDBERG T
Citation: M. Pritchard et al., BACTERIAL EXPRESSION OF FUNCTIONAL HUMAN P450 MONOOXYGENASE SYSTEMS FOR DRUG DEVELOPMENT, Naunyn-Schmiedeberg's archives of pharmacology, 355(4), 1997, pp. 503-503
INFLUENCE OF TRANS-N-6-DEOXYADENOSINE ADDUCTS OF VARIOUS POLYCYCLIC AROMATIC HYDROCARBON ANTI-DIOL EPOXIDES PLACED AT CODON-61 OF PARTIAL HUMAN HA-RAS PROTOONCOGENE SEQUENCES ON THE ACTION OF ESCHERICHIA-COLI POL-I, HIV-1 RT AND CALF THYMUS POL-BETA
Authors: KROTH H HORLACHER J AMACKER M MAGA G HUBSCHER U FRIEDBERG T OESCH F SEIDEL A
Citation: H. Kroth et al., INFLUENCE OF TRANS-N-6-DEOXYADENOSINE ADDUCTS OF VARIOUS POLYCYCLIC AROMATIC HYDROCARBON ANTI-DIOL EPOXIDES PLACED AT CODON-61 OF PARTIAL HUMAN HA-RAS PROTOONCOGENE SEQUENCES ON THE ACTION OF ESCHERICHIA-COLI POL-I, HIV-1 RT AND CALF THYMUS POL-BETA, Naunyn-Schmiedeberg's archives of pharmacology, 355(4), 1997, pp. 632-632
THE MEMBRANE ANCHOR OF MICROSOMAL EPOXIDE HYDROLASE FROM HUMAN, RAT AND RABBIT DISPLAYS AN UNEXPECTED MEMBRANE TOPOLOGY
Authors: HOLLER R ARAND M MECKEY A OESCH F FRIEDBERG T
Citation: R. Holler et al., THE MEMBRANE ANCHOR OF MICROSOMAL EPOXIDE HYDROLASE FROM HUMAN, RAT AND RABBIT DISPLAYS AN UNEXPECTED MEMBRANE TOPOLOGY, Biochemical and biophysical research communications, 236(3), 1997, pp. 754-759
HIGH-LEVELS OF RECOMBINANT CYP3A4 EXPRESSION IN CHINESE-HAMSTER OVARYCELLS ARE MODULATED BY COEXPRESSED HUMAN P450 REDUCTASE AND HEMIN SUPPLEMENTATION
Authors: DING SH YAO DG BURCHELL B WOLF CR FRIEDBERG T
Citation: Sh. Ding et al., HIGH-LEVELS OF RECOMBINANT CYP3A4 EXPRESSION IN CHINESE-HAMSTER OVARYCELLS ARE MODULATED BY COEXPRESSED HUMAN P450 REDUCTASE AND HEMIN SUPPLEMENTATION, Archives of biochemistry and biophysics, 348(2), 1997, pp. 403-410
A GENERAL STRATEGY FOR THE EXPRESSION OF RECOMBINANT HUMAN CYTOCHROMEP450S IN ESCHERICHIA-COLI USING BACTERIAL SIGNAL PEPTIDES - EXPRESSION OF CYP3A4, CYP2A6, AND CYP2E1
Authors: PRITCHARD MP OSSETIAN R LI DN HENDERSON CJ BURCHELL B WOLF CR FRIEDBERG T
Citation: Mp. Pritchard et al., A GENERAL STRATEGY FOR THE EXPRESSION OF RECOMBINANT HUMAN CYTOCHROMEP450S IN ESCHERICHIA-COLI USING BACTERIAL SIGNAL PEPTIDES - EXPRESSION OF CYP3A4, CYP2A6, AND CYP2E1, Archives of biochemistry and biophysics, 345(2), 1997, pp. 342-354
THE CATALYTIC ACTIVITY OF THE ENDOPLASMIC RETICULUM-RESIDENT PROTEIN MICROSOMAL EPOXIDE HYDROLASE TOWARDS CARCINOGENS IS RETAINED ON INVERSION OF ITS MEMBRANE TOPOLOGY
Authors: FRIEDBERG T HOLLER R LOLLMANN B ARAND M OESCH F
Citation: T. Friedberg et al., THE CATALYTIC ACTIVITY OF THE ENDOPLASMIC RETICULUM-RESIDENT PROTEIN MICROSOMAL EPOXIDE HYDROLASE TOWARDS CARCINOGENS IS RETAINED ON INVERSION OF ITS MEMBRANE TOPOLOGY, Biochemical journal, 319, 1996, pp. 131-136
RECOMBINANT-DNA TECHNOLOGY AS AN INVESTIGATIVE TOOL IN DRUG-METABOLISM RESEARCH
Authors: FRIEDBERG T WOLF CR
Citation: T. Friedberg et Cr. Wolf, RECOMBINANT-DNA TECHNOLOGY AS AN INVESTIGATIVE TOOL IN DRUG-METABOLISM RESEARCH, Advanced drug delivery reviews, 22(1-2), 1996, pp. 187-213
IDENTIFICATION OF 2 MONOOXYGENASES, CYP2B15 AND CYP2B12, HIGHLY EXPRESSED IN RAT SKIN
Authors: KEENEY DS SKINNER C FRIEDBERG T
Citation: Ds. Keeney et al., IDENTIFICATION OF 2 MONOOXYGENASES, CYP2B15 AND CYP2B12, HIGHLY EXPRESSED IN RAT SKIN, Journal of investigative dermatology, 106(4), 1996, pp. 576-576
COEXPRESSION OF A HUMAN P450 (CYP3A4) AND P450 REDUCTASE GENERATES A HIGHLY FUNCTIONAL MONOOXYGENASE SYSTEM IN ESCHERICHIA-COLI
Authors: BLAKE JAR PRITCHARD M DING SH SMITH GCM BURCHELL B WOLF CR FRIEDBERG T
Citation: Jar. Blake et al., COEXPRESSION OF A HUMAN P450 (CYP3A4) AND P450 REDUCTASE GENERATES A HIGHLY FUNCTIONAL MONOOXYGENASE SYSTEM IN ESCHERICHIA-COLI, FEBS letters, 397(2-3), 1996, pp. 210-214
FUNCTIONAL COEXPRESSION OF CYP2D6 AND CYP3A4 WITH RAT NADPH-CYTOCHROME P450 REDUCTASE IN SACCHAROMYCES-CEREVISIAE
Authors: BANDERA M WOLF CR BURCHELL B FRIEDBERG T
Citation: M. Bandera et al., FUNCTIONAL COEXPRESSION OF CYP2D6 AND CYP3A4 WITH RAT NADPH-CYTOCHROME P450 REDUCTASE IN SACCHAROMYCES-CEREVISIAE, British Journal of Pharmacology, 119, 1996, pp. 335-335
RELATIONSHIP BETWEEN THE MICROSOMAL EPOXIDE HYDROLASE AND THE HEPATOCELLULAR TRANSPORT OF BILE-ACIDS AND XENOBIOTICS
Authors: HONSCHA W PLATTE HD OESCH F FRIEDBERG T
Citation: W. Honscha et al., RELATIONSHIP BETWEEN THE MICROSOMAL EPOXIDE HYDROLASE AND THE HEPATOCELLULAR TRANSPORT OF BILE-ACIDS AND XENOBIOTICS, Biochemical journal, 311, 1995, pp. 975-979
EXPRESSION AND ALTERNATIVE SPLICING OF THE CYTOCHROME-P-450 CYP2A7
Authors: DING SH LAKE BG FRIEDBERG T WOLF CR
Citation: Sh. Ding et al., EXPRESSION AND ALTERNATIVE SPLICING OF THE CYTOCHROME-P-450 CYP2A7, Biochemical journal, 306, 1995, pp. 161-166
ONCOGENE OVEREXPRESSION IN NON-SMALL-CELL LUNG-CANCER TISSUE - PREVALENCE AND CLINICOPATHOLOGICAL SIGNIFICANCE
Authors: LORENZ J FRIEDBERG T PAULUS R OESCH F FERLINZ R
Citation: J. Lorenz et al., ONCOGENE OVEREXPRESSION IN NON-SMALL-CELL LUNG-CANCER TISSUE - PREVALENCE AND CLINICOPATHOLOGICAL SIGNIFICANCE, The Clinical investigator, 72(2), 1994, pp. 156-163
THE MICROSOMAL EPOXIDE HYDROLASE HAS A SINGLE MEMBRANE SIGNAL ANCHOR SEQUENCE WHICH IS DISPENSABLE FOR THE CATALYTIC ACTIVITY OF THIS PROTEIN
Authors: FRIEDBERG T LOLLMANN B BECKER R HOLLER R OESCH F
Citation: T. Friedberg et al., THE MICROSOMAL EPOXIDE HYDROLASE HAS A SINGLE MEMBRANE SIGNAL ANCHOR SEQUENCE WHICH IS DISPENSABLE FOR THE CATALYTIC ACTIVITY OF THIS PROTEIN, Biochemical journal, 303, 1994, pp. 967-972
STUDIES ON THE IMPORTANCE OF MICROSOMAL EPOXIDE HYDROLASE IN THE DETOXIFICATION OF ARENE OXIDES USING THE HETEROLOGOUS EXPRESSION OF THE ENZYME IN MAMMALIAN-CELLS
Authors: FRIEDBERG T BECKER R OESCH F GLATT H
Citation: T. Friedberg et al., STUDIES ON THE IMPORTANCE OF MICROSOMAL EPOXIDE HYDROLASE IN THE DETOXIFICATION OF ARENE OXIDES USING THE HETEROLOGOUS EXPRESSION OF THE ENZYME IN MAMMALIAN-CELLS, Carcinogenesis, 15(2), 1994, pp. 171-175
MECHANISM-BASED PREDICTIONS OF INTERACTIONS
Authors: OESCH F OESCHBARTLOMOWICZ B ARENS J FANDRICH F VOGEL E FRIEDBERG T GLATT H
Citation: F. Oesch et al., MECHANISM-BASED PREDICTIONS OF INTERACTIONS, Environmental health perspectives, 102, 1994, pp. 5-9
SEQUENCE SIMILARITY OF MAMMALIAN EPOXIDE HYDROLASES TO THE BACTERIAL HALOALKANE DEHALOGENASE AND OTHER RELATED PROTEINS - IMPLICATION FOR THE POTENTIAL CATALYTIC MECHANISM OF ENZYMATIC EPOXIDE HYDROLYSIS
Authors: ARAND M GRANT DF BEETHAM JK FRIEDBERG T OESCH F HAMMOCK BD
Citation: M. Arand et al., SEQUENCE SIMILARITY OF MAMMALIAN EPOXIDE HYDROLASES TO THE BACTERIAL HALOALKANE DEHALOGENASE AND OTHER RELATED PROTEINS - IMPLICATION FOR THE POTENTIAL CATALYTIC MECHANISM OF ENZYMATIC EPOXIDE HYDROLYSIS, FEBS letters, 338(3), 1994, pp. 251-256
Risultati: 1-25 | 26-26