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Results: 1-18 |
Results: 18
Positioning of the carboxamide side chain in 11-oxo-11H-indeno[1,2-b]quinolinecarboxamide anticancer agents: Effects on cytotoxicity
Authors: Deady, LW Desneves, J Kaye, AJ Finlay, GJ Baguley, BC Denny, WA
Citation: Lw. Deady et al., Positioning of the carboxamide side chain in 11-oxo-11H-indeno[1,2-b]quinolinecarboxamide anticancer agents: Effects on cytotoxicity, BIO MED CH, 9(2), 2001, pp. 445-452
Dicationic bis(9-methylphenazine-1-carboxamides): Relationships between biological activity and linker chain structure for a series of potent topoisomerase targeted anticancer drugs
Authors: Gamage, SA Spicer, JA Finlay, GJ Stewart, AJ Charlton, P Baguley, BC Denny, WA
Citation: Sa. Gamage et al., Dicationic bis(9-methylphenazine-1-carboxamides): Relationships between biological activity and linker chain structure for a series of potent topoisomerase targeted anticancer drugs, J MED CHEM, 44(9), 2001, pp. 1407-1415
Synthesis and cytotoxic activity of 7-Oxo-7H-dibenz[f,ij]isoquinoline and 7-oxo-7H-benzo[e]perimidine derivatives
Authors: Bu, XY Deady, LW Finlay, GJ Baguley, BC Denny, WA
Citation: Xy. Bu et al., Synthesis and cytotoxic activity of 7-Oxo-7H-dibenz[f,ij]isoquinoline and 7-oxo-7H-benzo[e]perimidine derivatives, J MED CHEM, 44(12), 2001, pp. 2004-2014
Synthesis and antitumor activity of some indeno[1,2-b]quinoline-based bis carboxamides
Authors: Deady, LW Desneves, J Kaye, AJ Finlay, GJ Baguley, BC Denny, WA
Citation: Lw. Deady et al., Synthesis and antitumor activity of some indeno[1,2-b]quinoline-based bis carboxamides, BIO MED CH, 8(5), 2000, pp. 977-984
Synthesis of substituted indeno[1,2-b]quinoline-6-carboxamides, [1]benzothieno[3,2-b]quinoline-4-carboxamides and 10H-quindoline-4-carboxamides: Evaluation of structure-activity relationships for cytotoxicity
Authors: Chen, JJ Deady, LW Desneves, J Kaye, AJ Finlay, GJ Baguley, BC Denny, WA
Citation: Jj. Chen et al., Synthesis of substituted indeno[1,2-b]quinoline-6-carboxamides, [1]benzothieno[3,2-b]quinoline-4-carboxamides and 10H-quindoline-4-carboxamides: Evaluation of structure-activity relationships for cytotoxicity, BIO MED CH, 8(10), 2000, pp. 2461-2466
Effects of protein binding on the in vitro activity of antitumour acridinederivatives and related anticancer drugs
Authors: Finlay, GJ Baguley, BC
Citation: Gj. Finlay et Bc. Baguley, Effects of protein binding on the in vitro activity of antitumour acridinederivatives and related anticancer drugs, CANC CHEMOT, 45(5), 2000, pp. 417-422
Synthesis and cytotoxic activity of carboxamide derivatives of benzimidazo[2,1-a]isoquinoline and pyrido[3 ',2 ': 4,5]imidazo[2,1-a]isoquinoline
Authors: Deady, LW Rodemann, T Finlay, GJ Baguley, BC Denny, WA
Citation: Lw. Deady et al., Synthesis and cytotoxic activity of carboxamide derivatives of benzimidazo[2,1-a]isoquinoline and pyrido[3 ',2 ': 4,5]imidazo[2,1-a]isoquinoline, ANTI-CAN DR, 15(5), 2000, pp. 339-346
Bis(phenazine-1-carboxamides): Structure-activity relationships for a new class of dual topoisomerase I/II-directed anticancer drugs
Authors: Spicer, JA Gamage, SA Rewcastle, GW Finlay, GJ Bridewell, DJA Baguley, BC Denny, WA
Citation: Ja. Spicer et al., Bis(phenazine-1-carboxamides): Structure-activity relationships for a new class of dual topoisomerase I/II-directed anticancer drugs, J MED CHEM, 43(7), 2000, pp. 1350-1358
Ring-substituted 11-oxo-11H-indeno[1,2-b]quinoline-6-carboxamides with similar patterns of cytotoxicity to the dual topo I/II inhibitor DACA
Authors: Deady, LW Desneves, J Kaye, AJ Thompson, M Finlay, GJ Baguley, BC Denny, WA
Citation: Lw. Deady et al., Ring-substituted 11-oxo-11H-indeno[1,2-b]quinoline-6-carboxamides with similar patterns of cytotoxicity to the dual topo I/II inhibitor DACA, BIO MED CH, 7(12), 1999, pp. 2801-2809
Inhibition of the action of the topoisomerase II poison amsacrine by simple aniline derivatives: Evidence for drug-protein interactions
Authors: Finlay, GJ Atwell, GJ Baguley, BC
Citation: Gj. Finlay et al., Inhibition of the action of the topoisomerase II poison amsacrine by simple aniline derivatives: Evidence for drug-protein interactions, ONCOL RES, 11(6), 1999, pp. 249-254
Short-term cultures of clinical tumor material: Potential contributions tooncology research
Authors: Baguley, BC Marshall, ES Finlay, GJ
Citation: Bc. Baguley et al., Short-term cultures of clinical tumor material: Potential contributions tooncology research, ONCOL RES, 11(3), 1999, pp. 115-124
Carbamate analogues of amsacrine active against non-cycling cells: relative activity against topoisomerases II alpha and beta
Authors: Turnbull, RM Meczes, EL Rogers, MP Lock, RB Sullivan, DM Finlay, GJ Baguley, BC Austin, CA
Citation: Rm. Turnbull et al., Carbamate analogues of amsacrine active against non-cycling cells: relative activity against topoisomerases II alpha and beta, CANC CHEMOT, 44(4), 1999, pp. 275-282
Mechanism of cytotoxicity of N-[2-(dimethylamino)ethyl] acridine-4-cariboxamide and of its 7-chloro derivative: the roles of topoisomerases I and II
Authors: Bridewell, DJA Finlay, GJ Baguley, BC
Citation: Dja. Bridewell et al., Mechanism of cytotoxicity of N-[2-(dimethylamino)ethyl] acridine-4-cariboxamide and of its 7-chloro derivative: the roles of topoisomerases I and II, CANC CHEMOT, 43(4), 1999, pp. 302-308
Cellular uptake of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA)
Authors: Haldane, A Finlay, GJ Hay, MP Denny, WA Baguley, BC
Citation: A. Haldane et al., Cellular uptake of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA), ANTI-CAN DR, 14(3), 1999, pp. 275-280
Dimeric analogues of non-cationic tricyclic aromatic carboxamides are a new class of cytotoxic agents
Authors: Spicer, JA Gamage, SA Atwell, GJ Finlay, GJ Baguley, BC Denny, WA
Citation: Ja. Spicer et al., Dimeric analogues of non-cationic tricyclic aromatic carboxamides are a new class of cytotoxic agents, ANTI-CAN DR, 14(3), 1999, pp. 281-289
5,7-disubstituted analogues of the mixed topoisomerase I/II poison N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA): DNA binding and patterns of cytotoxicity
Authors: Spicer, JA Finlay, GJ Baguley, BC Velea, L Graves, DE Denny, WA
Citation: Ja. Spicer et al., 5,7-disubstituted analogues of the mixed topoisomerase I/II poison N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA): DNA binding and patterns of cytotoxicity, ANTI-CAN DR, 14(1), 1999, pp. 37-45
Cytotoxicity of salicylaldehyde benzoylhydrazone analogs and their transition metal complexes: quantitative structure-activity relationships
Authors: Ainscough, EW Brodie, AM Denny, WA Finlay, GJ Gothe, SA Ranford, JD
Citation: Ew. Ainscough et al., Cytotoxicity of salicylaldehyde benzoylhydrazone analogs and their transition metal complexes: quantitative structure-activity relationships, J INORG BIO, 77(3-4), 1999, pp. 125-133
Structure-activity relationships for substituted bis(acridine-4-calrboxamides): A new class of anticancer agents
Authors: Gamage, SA Spicer, JA Atwell, GJ Finlay, GJ Baguley, BC Denny, WA
Citation: Sa. Gamage et al., Structure-activity relationships for substituted bis(acridine-4-calrboxamides): A new class of anticancer agents, J MED CHEM, 42(13), 1999, pp. 2383-2393
Risultati: 1-18 |