Authors:
Elholm, M
Hollas, H
Issalene, C
Barroso, JFV
Berge, RK
Flatmark, T
Citation: M. Elholm et al., Transient up-regulation of liver mitochondrial thymidine kinase activity in proliferating mitochondria, IUBMB LIFE, 51(2), 2001, pp. 99-104
Citation: Ap. Doskeland et T. Flatmark, Conjugation of phenylalanine hydroxylase with polyubiquitin chains catalysed by rat liver enzymes, BBA-PROT ST, 1547(2), 2001, pp. 379-386
Citation: Oa. Andersen et al., High resolution crystal structures of the catalytic domain of human phenylalanine hydroxylase in its catalytically active Fe(II) form and binary complex with tetrahydrobiopterin, J MOL BIOL, 314(2), 2001, pp. 279-291
Authors:
Hagedoorn, PL
Schmidt, PP
Andersson, KK
Hagen, WR
Flatmark, T
Martinez, A
Citation: Pl. Hagedoorn et al., The effect of substrate, dihydrobiopterin, and dopamine on the EPR spectroscopic properties and the midpoint potential of the catalytic iron in recombinant human phenylalanine hydroxylase, J BIOL CHEM, 276(25), 2001, pp. 22850-22856
Authors:
Elholm, R
Dam, I
Jorgensen, C
Krogsdam, AM
Holst, D
Kratchmarova, I
Gottlicher, M
Gustafsson, JA
Berge, R
Flatmark, T
Knudsen, J
Mandrup, S
Kristiansen, K
Citation: R. Elholm et al., Acyl-CoA esters antagonize the effects of ligands on peroxisome proliferator-activated receptor alpha conformation, DNA binding, and interaction withco-factors, J BIOL CHEM, 276(24), 2001, pp. 21410-21416
Citation: E. Bjorgo et al., A comparison of kinetic and regulatory properties of the tetrameric and dimeric forms of wild-type and Thr427 -> Pro mutant human phenylalanine hydroxylase - Contribution of the flexible hinge region Asp425-Gln429 to the tetramerization and cooperative substrate binding, EUR J BIOCH, 268(4), 2001, pp. 997-1005
Citation: T. Flatmark et al., Use of surface plasmon resonance for real-time measurements of the global conformational transition in human phenylalanine hydroxylase in response tosubstrate binding and catalytic activation, ANALYT BIOC, 294(2), 2001, pp. 95-101
Authors:
Elholm, M
Garras, A
Neve, S
Tornehave, D
Lund, TB
Skorve, J
Flatmark, T
Kristiansen, K
Berge, RK
Citation: M. Elholm et al., Long-chain acyl-CoA esters and acyl-CoA binding protein are present in thenucleus of rat liver cells, J LIPID RES, 41(4), 2000, pp. 538-545
Citation: M. Ying et al., The p58-positive pre-Golgi intermediates consist of distinct subpopulations of particles that show differential binding of COPI and COPII coats and contain vacuolar H+-ATPase, J CELL SCI, 113(20), 2000, pp. 3623-3638
Citation: T. Solstad et T. Flatmark, Microheterogeneity of recombinant human phenylalanine hydroxylase as a result of nonenzymatic deamidations of labile amide containing amino acids - Effects on catalytic and stability properties, EUR J BIOCH, 267(20), 2000, pp. 6302-6310
Authors:
Husebye, ES
Boe, AS
Rorsman, F
Kampe, O
Aakvaag, A
Rygh, T
Flatmark, T
Haavik, J
Citation: Es. Husebye et al., Inhibition of aromatic L-amino acid decarboxylase activity by human autoantibodies, CLIN EXP IM, 120(3), 2000, pp. 420-423
Authors:
Erlandsen, H
Bjorgo, E
Flatmark, T
Stevens, RC
Citation: H. Erlandsen et al., Crystal structure and site-specific mutagenesis of pterin-bound human phenylalanine hydroxylase, BIOCHEM, 39(9), 2000, pp. 2208-2217
Authors:
Almas, B
Toska, K
Teigen, K
Groehn, V
Pfleiderer, W
Martinez, A
Flatmark, T
Haavik, J
Citation: B. Almas et al., A kinetic and conformational study on the interaction of tetrahydropteridines with tyrosine hydroxylase, BIOCHEM, 39(45), 2000, pp. 13676-13686
Citation: O. Terland et T. Flatmark, Energy-dependent accumulation of calcium antagonists in catecholamine storage vesicles, BIOCH PHARM, 59(2), 2000, pp. 123-129
Citation: O. Terland et T. Flatmark, Drug-induced parkinsonism: cinnarizine and flunarizine are potent uncouplers of the vacuolar H+-ATPase in catecholamine storage vesicles, NEUROPHARM, 38(6), 1999, pp. 879-882
Authors:
Flatmark, T
Almas, B
Knappskog, PM
Berge, SV
Svebak, RM
Chehin, R
Muga, A
Martinez, A
Citation: T. Flatmark et al., Tyrosine hydroxylase binds tetrahydrobiopterin cofactor with negative cooperativity, as shown by kinetic analyses and surface plasmon resonance detection, EUR J BIOCH, 262(3), 1999, pp. 840-849
Citation: T. Flatmark et Rc. Stevens, Structural insight into the aromatic amino acid hydroxylases and their disease-related mutant forms, CHEM REV, 99(8), 1999, pp. 2137-2160