Authors:
Ferorelli, S
Franchini, C
Loiodice, F
Perrone, MG
Scilimati, A
Sinicropi, MS
Tortorella, P
Citation: S. Ferorelli et al., Lipase-mediated kinetic resolution of rigid clofibrate analogues with lipid-modifying activity, TETRAHEDR-A, 12(6), 2001, pp. 853-862
Authors:
Talon, S
De Luca, A
De Bellis, M
Desaphy, JF
Lentini, G
Scilimati, A
Corbo, F
Franchini, C
Tortorella, P
Jockusch, H
Camerino, DC
Citation: S. Talon et al., Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+ channels enhancing the antimyotonic activity in vivo, BR J PHARM, 134(7), 2001, pp. 1523-1531
Authors:
Di Nunno, L
Franchini, C
Scilimati, A
Sinicropi, MS
Tortorella, P
Citation: L. Di Nunno et al., Chemical and chemoenzymatic routes to 1-(benzothiazol-2-ylsulfanyl)-3-chloropropan-2-ol, a precursor of drugs with potential beta-blocker activity, TETRAHEDR-A, 11(7), 2000, pp. 1571-1583
Authors:
Carocci, A
Catalano, A
Corbo, F
Duranti, A
Amoroso, R
Franchini, C
Lentini, G
Tortorella, V
Citation: A. Carocci et al., Stereospecific synthesis of mexiletine and related compounds: Mitsunobu versus Williamson reaction, TETRAHEDR-A, 11(17), 2000, pp. 3619-3634
Authors:
Duranti, A
Franchini, C
Lentini, G
Loiodice, F
Tortorella, V
De Luca, A
Pierno, S
Camerino, DC
Citation: A. Duranti et al., Homologation of mexiletine alkyl chain and stereoselective blockade of skeletal muscle sodium channels, EUR J MED C, 35(1), 2000, pp. 147-156
Authors:
De Luca, A
Natuzzi, F
Desaphy, JF
Loni, G
Lentini, G
Franchini, C
Tortorella, V
Camerino, DC
Citation: A. De Luca et al., Molecular determinants of mexiletine structure for potent and use-dependent block of skeletal muscle sodium channels, MOLEC PHARM, 57(2), 2000, pp. 268-277
Authors:
Franchini, C
Corbo, F
Lentini, G
Bruno, G
Scilimati, A
Tortorella, V
Camerino, DC
De Luca, A
Citation: C. Franchini et al., Synthesis of new 2,6-prolylxylidide analogues of tocainide as stereoselective blockers of voltage-gated Na+ channels with increased potency and improved use-dependent activity, J MED CHEM, 43(20), 2000, pp. 3792-3798
Authors:
Di Nunno, L
Franchini, C
Nacci, A
Scilimati, A
Sinicropi, MS
Citation: L. Di Nunno et al., Baker's yeast-induced asymmetric reduction of alpha-ketosulfides: synthesis of optically active 1-(benzothiazol-2-ylsulfanyl)-2-alkanols, 2-alkanols,and thiiranes, TETRAHEDR-A, 10(10), 1999, pp. 1913-1926
Authors:
Desaphy, JF
Camerino, DC
Franchini, C
Lentini, G
Tortorella, V
De Luca, A
Citation: Jf. Desaphy et al., Increased hindrance on the chiral carbon atom of mexiletine enhances the block of rat skeletal muscle Na+ channels in a model of myotonia induced by ATX, BR J PHARM, 128(6), 1999, pp. 1165-1174