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Results: 1-16 |
Results: 16
Antibody response to DT-GM, a novel fusion toxin consisting of a truncateddiphtheria toxin (DT) linked to human granulocyte-macrophage colony stimulating factor (GM), during a phase I trial of patients with relapsed or refractory acute myeloid leukemia
Authors: Hall, PD Virella, G Willoughby, T Atchley, DH Kreitman, RJ Frankel, AE
Citation: Pd. Hall et al., Antibody response to DT-GM, a novel fusion toxin consisting of a truncateddiphtheria toxin (DT) linked to human granulocyte-macrophage colony stimulating factor (GM), during a phase I trial of patients with relapsed or refractory acute myeloid leukemia, CLIN IMMUNO, 100(2), 2001, pp. 191-197
Novel therapeutics for chemotherapy-resistant acute myeloid leukaemia
Authors: Frankel, AE Schuster, MW Jurcic, JG
Citation: Ae. Frankel et al., Novel therapeutics for chemotherapy-resistant acute myeloid leukaemia, BIODRUGS, 15(1), 2001, pp. 55-71
Oncogene-dependent engraftment of human myeloid leukemia cells in immunosuppressed mice
Authors: Kiser, M McCubrey, JA Steelman, LS Shelton, JG Ramage, J Alexander, RL Kucera, GL Pettenati, M Willingham, MC Miller, MS Frankel, AE
Citation: M. Kiser et al., Oncogene-dependent engraftment of human myeloid leukemia cells in immunosuppressed mice, LEUKEMIA, 15(5), 2001, pp. 814-818
High affinity interleukin-3 receptor expression on blasts from patients with acute myelogenous leukemia correlates with cytotoxicity of a diphtheria toxin/IL-3 fusion protein
Authors: Alexander, RL Ramage, J Kucera, GL Caligiuri, MA Frankel, AE
Citation: Rl. Alexander et al., High affinity interleukin-3 receptor expression on blasts from patients with acute myelogenous leukemia correlates with cytotoxicity of a diphtheria toxin/IL-3 fusion protein, LEUK RES, 25(10), 2001, pp. 875-881
Enhanced ceramide generation and induction of apoptosis in human leukemia cells exposed to DT388-granulocyte-macrophage colony-stimulating factor (GM-CSF), a truncated diphtheria toxin fused to human GM-CSF
Authors: Senchenkov, A Han, TY Wang, HT Frankel, AE Kottke, TJ Kaufmann, SH Cabot, MC
Citation: A. Senchenkov et al., Enhanced ceramide generation and induction of apoptosis in human leukemia cells exposed to DT388-granulocyte-macrophage colony-stimulating factor (GM-CSF), a truncated diphtheria toxin fused to human GM-CSF, BLOOD, 98(6), 2001, pp. 1927-1934
Distinct domains of the human granulocyte-macrophage colony-stimulating factor receptor alpha subunit mediate activation of Jak/Stat signaling and differentiation
Authors: Lilly, MB Zemskova, M Frankel, AE Salo, J Kraft, AS
Citation: Mb. Lilly et al., Distinct domains of the human granulocyte-macrophage colony-stimulating factor receptor alpha subunit mediate activation of Jak/Stat signaling and differentiation, BLOOD, 97(6), 2001, pp. 1662-1670
Cell surface receptor-targeted therapy of acute myeloid leukemia: A review
Authors: Frankel, AE Sievers, EL Scheinberg, DA
Citation: Ae. Frankel et al., Cell surface receptor-targeted therapy of acute myeloid leukemia: A review, CANC BIO R, 15(5), 2000, pp. 459-476
Targeted toxins
Authors: Frankel, AE Kreitman, RJ Sausville, EA
Citation: Ae. Frankel et al., Targeted toxins, CLIN CANC R, 6(2), 2000, pp. 326-334
In vitro interleukin-3 binding to leukemia cells predicts cytotoxicity of a diphtheria toxin/IL-3 fusion protein
Authors: Alexander, RL Kucera, GL Klein, B Frankel, AE
Citation: Rl. Alexander et al., In vitro interleukin-3 binding to leukemia cells predicts cytotoxicity of a diphtheria toxin/IL-3 fusion protein, BIOCONJ CHE, 11(4), 2000, pp. 564-568
Diphtheria toxin fused to human interleukin-3 is toxic to blasts from patients with myeloid leukemias
Authors: Frankel, AE McCubrey, JA Miller, MS Delatte, S Ramage, J Kiser, M Kucera, GL Alexander, RL Beran, M Tagge, EP Kreitman, RJ Hogge, DE
Citation: Ae. Frankel et al., Diphtheria toxin fused to human interleukin-3 is toxic to blasts from patients with myeloid leukemias, LEUKEMIA, 14(4), 2000, pp. 576-585
Characterization of diphtheria fusion proteins targeted to the human interleukin-3 receptor
Authors: Frankel, AE Ramage, J Kiser, M Alexander, R Kucera, G Miller, MS
Citation: Ae. Frankel et al., Characterization of diphtheria fusion proteins targeted to the human interleukin-3 receptor, PROTEIN ENG, 13(8), 2000, pp. 575-581
High-level expression and purification of the recombinant diphtheria fusion toxin DTGM for PHASE I clinical trials
Authors: Frankel, AE Ramage, J Latimer, A Feely, T Delatte, S Hall, P Tagge, E Kreitman, R Willingham, M
Citation: Ae. Frankel et al., High-level expression and purification of the recombinant diphtheria fusion toxin DTGM for PHASE I clinical trials, PROT EX PUR, 16(1), 1999, pp. 190-201
DT388-GM-CSF, a novel fusion toxin consisting of a truncated diphtheria toxin fused to human granulocyte-macrophage colony-stimulating factor, prolongs host survival in a SCID mouse model of acute myeloid leukemia
Authors: Hall, PD Willingham, MC Kreitman, RJ Frankel, AE
Citation: Pd. Hall et al., DT388-GM-CSF, a novel fusion toxin consisting of a truncated diphtheria toxin fused to human granulocyte-macrophage colony-stimulating factor, prolongs host survival in a SCID mouse model of acute myeloid leukemia, LEUKEMIA, 13(4), 1999, pp. 629-633
Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factorand Ara-C exert synergistic toxicity against human AML HL-60 cells
Authors: Kim, CN Bhalla, K Kreitman, RJ Willingham, MC Hall, P Tagge, EP Jia, T Frankel, AE
Citation: Cn. Kim et al., Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factorand Ara-C exert synergistic toxicity against human AML HL-60 cells, LEUK RES, 23(6), 1999, pp. 527-538
Toxicology and pharmacokinetics of DTGM, a fusion toxin consisting of a truncated diphtheria toxin (DT388) linked to human granulocyte-macrophage colony-stimulating factor, in cynomolgus monkeys
Authors: Hotchkiss, CE Hall, PD Cline, JM Willingham, MC Kreitman, RJ Gardin, J Latimer, A Ramage, J Feely, T DeLatte, S Tagge, EP Frankel, AE
Citation: Ce. Hotchkiss et al., Toxicology and pharmacokinetics of DTGM, a fusion toxin consisting of a truncated diphtheria toxin (DT388) linked to human granulocyte-macrophage colony-stimulating factor, in cynomolgus monkeys, TOX APPL PH, 158(2), 1999, pp. 152-160
Clinical applications of immunotoxins - Conclusions
Authors: Frankel, AE Willingham, MC
Citation: Ae. Frankel et Mc. Willingham, Clinical applications of immunotoxins - Conclusions, CURR T MICR, 234, 1998, pp. 115-120
Risultati: 1-16 |